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Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-hui Jiang hui-Li Kang Yi Jiang Hua-Wei Zhang Xiao-Mei Song Yu-Ze Li wen-Li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Formation,evolution,reconstruction of black shales and their influence on shale oil and gas resource

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China Geology 2024年第3期7卷 551-585页

作者： Shi-zhen Li Qiu-chen Xu Mu Liu Guo-heng Liu Yi-fan Li wen-yang Wang Xiao-guang Yang Wei-bin Liu Yan-fei An Peng Sun Tao Liu Jiang-hui Ding Qian-chao Li Chao-gang Fang State Key Laboratory of Continental Shale Oil Beijing 100083China The Key Laboratory of Unconventional Oil and Gas Geology China Geological SurveyBeijing 100083China Oil and Gas Survey China Geological SurveyMinistry of Natural ResourcesBeijing 100083China State Key Laboratory of Lithospheric and Environmental Coevolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China School of Geosciences China University of Petroleum(East China)Qingdao 266580China School of Energy Resources China University of Geosciences(Beijing)Beijing 100083China Key Laboratory of Petroleum Resources Research Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China School of Resource and Environment Engineering Anhui UniversityHefei 230601China Yangtze University Wuhan 430100China Nanjing Center China Geological SurveyNanjing 210016China National Elite Institute of Engineering CNPCBeijing 100096China

Black shales are important products of material cycling and energy exchange among the lithosphere,atmosphere,hydrosphere,and *** are widely distributed throughout geological history and provide essential energy and mineral resources for the development of human *** also record the evolution process of the earth and improve the understanding of the *** review focuses on the diagenesis and formation mechanisms of black shales sedimentation,composition,evolution,and reconstruction,which have had a significant impact on the formation and enrichment of shale oil and *** terms of sedimentary environment,black shales can be classified into three types:Marine,terrestrial,and marine-terrestrial transitional *** formation processes include mechanisms such as eolian input,hypopycnal flow,gravity-driven and offshore bottom *** a geological perspective,the formation of black shales is often closely related to global or regional major geological *** enrichment of organic matter is generally the result of the interaction and coupling of several factors such as primary productivity,water redox condition,and sedimentation *** terms of evolution,black shales have undergone diagenetic evolution of inorganic minerals,thermal evolution of organic matter and hydrocarbon generation,interactions between organic matter and inorganic minerals,and pore *** terms of reconstruction,the effects of fold deformation,uplift and erosion,and fracturing have changed the stress state of black shale reservoirs,thereby having a significant impact on the pore *** activity promotes the formation of veins,and have changed the material composition,stress structure,and reservoir properties of black *** resource effects,the deposition of black shales is fundamental for shale oil and gas resources,the evolution of black shales promotes the shale oil and gas formation and storage,and the reconstruction of black shales wou

关键词： Black shales Shale oil and gas Resource effects Sedimentary environment Sedimentary process Organic matter accumulation Diagenetic evolution Thermal evolution Organic matter and inorganic minerals Tectonic reconstruction Oil and gas exploration engineering Veins Fluid activity

Recent Advances on Ruthenium-based Electrocatalysts for Lithium-oxygen Batteries

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电化学（中英文） 2024年第8期30卷 1-16页

作者： Yu-Zhe Wang Zhuo-Liang Jiang Bo wen Yao-hui Huang Fu-Jun Li Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) College of ChemistryNankai UniversityTianjin 300071China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China

Rechargeable lithium-oxygen(Li-O_(2))batteries have attracted wide attention due to their high energy ***,the sluggish cathode kinetics results in high overvoltage and poor cycling ***(Ru)-based electrocatalysts have been demonstrated to be promising cathode catalysts to promote oxygen evolution reaction(OER).It facilitates decomposition of lithium peroxide(Li_(2)O_(2))by adjusting Li_(2)O_(2) morphologies,which is due to the strong interaction between Ru-based catalyst and superoxide anion(O_(2))*** this review,the design strategies of Ru-based electrocatalysts are introduced to enhance their OER catalytic kinetics in Li-O_(2) *** configurations of Ru-based catalysts,including metal particles(Ru metal and alloys),single-atom catalysts,and Ru-loaded compounds with various substrates(carbon materials,metal oxides/sulfides),have been summarized to regulate the electronic structure and the matrix architecture of the Ru-based *** structure-property relationship of Ru-based catalysts is discussed for a better understanding of the Li_(2)O_(2) decomposition mechanism at the cathode ***,the challenges of Ru-based electrocatalysts are proposed for the future development of Li-O_(2) batteries.

关键词： Lithium-oxygen battery Ruthenium-based electrocatalyst Reaction mechanism Reaction kinetics Overvoltage

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城市小学课后服务优质供给的困境与突破

教学与管理 2024年第15期 35-39页

作者：惠文妮顾玉军宁夏大学教师教育学院银川750021

城市小学课后服务作为时代发展的必然产物,在我国社会主要矛盾的转化下势必走向高质量发展的阶段。马克思需要理论对人的需要的层次划分指明课后服务供给目标可分为“生存”、“享受”和“发展”三个层次,为实现城市小学课后服务优质供... 详细信息

城市小学课后服务作为时代发展的必然产物,在我国社会主要矛盾的转化下势必走向高质量发展的阶段。马克思需要理论对人的需要的层次划分指明课后服务供给目标可分为“生存”、“享受”和“发展”三个层次,为实现城市小学课后服务优质供给指引了方向。当下的城市小学课后服务供给体系已经实现了基本供给,但仍存在着供给主体责任不明、供给形式单一、供给质量参差不齐等问题,离优质供给尚有差距。因此,从明确课后服务供给主体责任、优化供给内容形式、提高供给质量三个方面提出课后服务优质供给保障的路径,实现城市小学课后服务优质供给。

关键词：城市小学课后服务课后服务优质供给马克思需要理论

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服务化与制造业全球价值链生产工序优化

国际贸易问题 2024年第3期 69-85页

作者：陈晓华杜文刘慧浙江理工大学经济管理学院

本文在科学测度服务化和制造业全球价值链生产工序偏优指数的基础上,从多维度剖析服务化对发展中国家制造业全球价值链生产工序优化的作用机理,并进一步从自身需求视角检验服务化的国际供应链风险效应。研究结果表明:服务化对制造业全... 详细信息

本文在科学测度服务化和制造业全球价值链生产工序偏优指数的基础上,从多维度剖析服务化对发展中国家制造业全球价值链生产工序优化的作用机理,并进一步从自身需求视角检验服务化的国际供应链风险效应。研究结果表明:服务化对制造业全球价值链生产工序具有动态持续优化功能。为此,服务化具有推进产业基础高级化和产业链现代化的“强链”效应,能推动制造业从全球价值链边缘工序走向核心工序。服务化不仅有助于提升人力资本和产品技术含量,还有助于提升政府的支持力度,这三个渠道也使服务化对制造业全球价值链生产工序优化表现出显著的正向效应。服务化会使一国制造业面临集中度更高的国际供应商,从而对本国制造业的国际供应链安全产生不利影响。因此,介入全球价值链高端工序的经济体既需大力提升核心中间品的自给能力,也需加强与国际供应商的合作关系。服务化程度偏低与制造业全球价值链生产工序偏优指数偏高共存的窘境表明,中国服务资源并未充分发挥其促进全球价值链生产工序优化的功能。这不仅造成了服务资源的低效配置与浪费,还导致制造业全球价值链生产工序攀升乏力。为此,中国加快服务化步伐的迫切性要远高于普通发展中国家。

关键词：服务化全球价值链生产工序发展中国家

Y元素对铸态 Mg-Al-Ca-Mn合金组织与耐腐蚀性能的影响

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热加工工艺 2024年第16期53卷 97-100页

作者：何卉温祥辉河南大学化学化工学院河南开封475001 郑州商业技师学院河南郑州450007 河南工业大学材料科学与工程学院河南郑州450001

采用金相显微镜、扫描电镜、XRD分析、腐蚀试验和电化学测试等研究了Mg-4Al-3Ca-0.7Mn-xY(x=0、0.8、1.5)铸态合金的微观组织与耐腐蚀性能。结果表明:未添加Y的Mg-4Al-3Ca-0.7Mn合金组织由α-Mg、Al2Ca相、Mg2Ca相组成。添加0.8wt%Y后,... 详细信息

采用金相显微镜、扫描电镜、XRD分析、腐蚀试验和电化学测试等研究了Mg-4Al-3Ca-0.7Mn-xY(x=0、0.8、1.5)铸态合金的微观组织与耐腐蚀性能。结果表明:未添加Y的Mg-4Al-3Ca-0.7Mn合金组织由α-Mg、Al2Ca相、Mg2Ca相组成。添加0.8wt%Y后,合金组织中晶粒得到明显细化,析出相变得细小,Al2Ca相、Mg2Ca相数量减少,并有Al2Y相生成。Y含量增加到1.5wt%时,合金晶粒细化效果不明显,大量Al2Y相聚集在晶界处呈网状分布。添加适量的Y可提高Mg-4Al-3Ca-0.7Mn-xY合金的耐腐蚀性,Y添加量为0.8wt%时,该合金的耐腐蚀性最佳。

关键词： Mg-Al-Ca-Mn-Y合金 Y元素微观组织耐腐蚀性

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角膜屈光术后白内障手术研究进展

眼科新进展 2024年第8期44卷 668-672页

作者：文子元张辉吉林大学第二医院眼科中心吉林省长春市130022

近些年,既往有角膜屈光手术史的白内障患者逐渐增多,为白内障手术带来诸多难点,如角膜内皮细胞密度降低、角膜完整性破坏、角膜曲率发生改变、人工晶状体(IOL)度数计算准确性降低等,增加了白内障手术的难度并影响术后满意度,是屈光白内... 详细信息

近些年,既往有角膜屈光手术史的白内障患者逐渐增多,为白内障手术带来诸多难点,如角膜内皮细胞密度降低、角膜完整性破坏、角膜曲率发生改变、人工晶状体(IOL)度数计算准确性降低等,增加了白内障手术的难度并影响术后满意度,是屈光白内障手术时代的重要挑战之一。现从角膜屈光术后行白内障手术难点、视力及视觉质量的影响因素以及屈光术后白内障患者术前准备、术中注意事项及术后处理方面进行阐述。为临床医师了解角膜屈光术后白内障手术的研究进展提供参考。

关键词：白内障角膜屈光术人工晶状体植入

Enhanced photothermal dehydration of methanol over W_(18)O_(49)/Au/SAPO-34 catalysts with broadened light absorption

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Rare Metals 2024年第3期43卷 1139-1152页

作者： Ya-Qin Tang Meng-Xia Yan Chang-Qian Lu Shao-Yuan Li Kui-Xian Wei Tao Qu wen-huiMa Yong-Nian Dai Kong-Zhai Li Da-Jun Luo Xue-Liang Zhang Yi-Ke Liu Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China School of Materials and Energy Engineering Guizhou Institute of TechnologyGuiyang550003China

Methanol-to-olefins(MTO)process is one of the most critical pathways to produce low carbon ***,the reaction is driven by thermal catalysis,which inevitably needs to consume large amounts of fossil *** a new technique to substitute for the fuel burning is urgent for MTO process to improve the industry prospects and ***,we report a novel W_(18)O_(49)/Au/SAPO-34(W/Au/S),a multifunctional photothermal catalyst for the MTO reaction.A high methanol conversion was achieved under xenonum(Xe)lamp irradiation,yielding methyl ether(ME)and ethylene as the main *** optimized W/Au/S catalysts showed ethylene yield as high as 250μmol in 60 min,which was 2.5 times higher than that of Au/*** physiochemical characterization revealed that the SAPO-34 molecular sieves were surrounded by Au and W_(18)O_(49)nanoparticles,which exhibited a strong localized surface plasmon resonance excitation around 540 nm and light absorption beyond 500 *** multifunctional catalysts showed a strong photothermal effect,arising from the broadened light absorption of Au and W_(18)O_(49)nanoparticles,leading to a temperature as high as 250℃on the surface of the *** study showed that the superior ethylene selectivity of W/Au/S catalysts was attributed to the moderating acidic sites of W_(18)O_(49)for methanol dehydration to *** research may provide new insight for designing heterostructures to improve photo-to-chemical conversion performance and is expected to accelerate progress toward the excellent multifunctional photothermal catalysts with broad light absorption for methanol activation and C-C bond formation.

关键词： Methanol conversion Ethylene Photothermal catalysis W_(18)O_(49) BrΦnsted-acid

Two stages power generation test of the hot dry rock exploration and production demonstration project in the Gonghe Basin,northeastern Qinghai-Tibet plateau,China

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China Geology 2024年第3期7卷 409-421页

作者： Er-yong Zhang Dong-guang wen Gui-ling Wang Xian-peng Jin Lin-you Zhang Hai-dong Wu wen-shi Wang Cheng-ming Ye Wei weng Kuan Li Jin-sheng Wu Xian-chun Tang Chong-yuan Zhang Qing-da Feng Sheng Lian Li-sha Hu Gui-lin Zhu Xing-long Xie Bin Wu Dan Wang Xue Niu Zhao-xuan Niu Dong-lin Liu hui Zhang wen-hao Xu Shu-qing Yao Li Yang Center for Hydrogeology and Environmental Geology Survey China Geological SurveyMinistry of Natural ResourcesTianjin 300304China Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesChina Geological SurveyShijiazhuang 050061China Institute of Exploration Techniques Chinese Academy of Geological SciencesChina Geological SurveyLangfang 065000China Institute of Exploration Engineering China Geological SurveyMinistry of Natural ResourcesBeijing 100083China Institute of Exploration Technology Chinese Academy of Geological SciencesChengdu 611734China Chinese Academy of Geological Sciences China Geological SurveyBeijing 100037China Institute of Geomechanics Chinese Academy of Geological SciencesChina Geological SurveyBeijing 100081China Geoscience Documentation Center China Geological SurveyMinistry of Natural ResourcesBeijing 100083China

The Hot Dry Rock(HDR)is considered as a clean and renewable energy,poised to significantly contribute to the global energy decarbonization *** HDR projects worldwide have accumulated valuable experience in efficient drilling and completion,reservoir construction,and fracture *** 2019,China Geological Survey(CGS)initiated a demonstration project of HDR exploration and production in the Gonghe Basin,aiming to overcome the setbacks faced by HDR *** the ensuing four years,the Gonghe HDR project achieved the first power generation in 2021,followed by the second power generation test in *** establishing the primary well group in the initial phase,two directional wells and one branch well were *** progress was made in successfully constructing the targeted reservoir,realizing inter-well connectivity,power generation and grid connection,implementing of the real-time micro-seismic monitoring.A closed-loop technical validation of the HDR exploration and production was ***,many technical challenges remain in the process of HDR industrialization,such as reservoir fracture network characterization,efficient drilling and completion,multiple fracturing treatment,continuous injection and production,as well as mitigation of induced seismicity and numerical simulation technology.

关键词： Power generation Hot dry rock(HDR) Enhanced geothermal system(EGS) Genesis mechanism Gonghe Basin Directional drilling Reservoir construction Circulation test Induced seismicity Clean energy exploration engineering