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Dynamic response mechanism and precursor characteristics of gneiss rockburst under different initial burial depths

Journal of Mountain Science 2024年第3期21卷 1004-1018页

作者： LIU Dongqiao sun Jie MENG wen HE Manchao ZHANG Chongyuan LI Ran CAO Binghao State Key Laboratory for Tunnel Engineering China University of Mining and TechnologyBeijing 100083China Key Laboratory of Active Tectonics and Geological Safety Ministry of Natural ResourcesInstitute of GeomechanicsChinese Academy of Geological SciencesBeijing 100081China School of Mechanics and Civil Engineering China University of Mining and TechnologyBeijing 100083China

To investigate the influence mechanism of geostress on rockburst characteristics,three groups of gneiss rockburst experiments were conducted under different initial geostress conditions.A high-speed photography system and acoustic emission(AE)monitoring system were used to monitor the entire rockburst process in real *** experimental results show that when the initial burial depth increases from 928 m to 1320 m,the proportion of large fracture scale in rockburst increases by 154.54%,and the AE energy increases by 565.63%,reflecting that the degree and severity of rockburst increase with the increase of burial *** then,two mechanisms are proposed to explain this effect,including(i)the increase of initial geostress improves the energy storage capacity of gneiss,and then,the excess energy which can be converted into kinetic energy of debris ejection increases,consequently,a more pronounced violent ejection phenomenon is observed at rockburst;(ii)the increase of initial geostress causes more sufficient plate cracks of gneiss after unloading ofσh,which provides a basis for more severe ejection of ***’s more,a precursor with clear physical meaning for rockburst is proposed under the framework of dynamic response process of crack ***,potential value in long term rockburst warning of the precursor obtained in this study is shown via the comparison of conventional precursor.

关键词： Traffic Engineering Gneiss Rockburst Crack propagation Excess energy Precursor characteristic

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Climate-Vegetation Coverage Interactions in the Hengduan Mountains Area, Southeastern Tibetan Plateau, and Their Downstream Effects

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Advances in Atmospheric Sciences 2024年第4期41卷 701-716页

作者： Congxi FANG Jinlei CHEN Chaojun OUYANG Lu WANG Changfeng sun Quan ZHANG Jun wen Key Laboratory of Mountain Hazards and Earth Surface Processes Institute of Mountain Hazards and EnvironmentChinese Academy of SciencesChengdu 610299China State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China College of Urban and Environmental Sciences Peking UniversityBeijing 100871China Institute of Global Environmental Change Xi’an Jiaotong UniversityXi’an 710049China The State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China College of Atmospheric Sciences Chengdu University of Information TechnologyChengdu 610225China

Little is known about the mechanism of climate-vegetation coverage coupled changes in the Tibetan Plateau(TP)region,which is the most climatically sensitive and ecologically fragile region with the highest terrain in the *** study,using multisource datasets(including satellite data and meteorological observations and reanalysis data)revealed the mutual feedback mechanisms between changes in climate(temperature and precipitation)and vegetation coverage in recent decades in the Hengduan Mountains Area(HMA)of the southeastern TP and their influences on climate in the downstream region,the Sichuan Basin(SCB).There is mutual facilitation between rising air temperature and increasing vegetation coverage in the HMA,which is most significant during winter,and then during spring,but insignificant during summer and *** temperature significantly enhances local vegetation coverage,and vegetation greening in turn heats the atmosphere via enhancing net heat flux from the surface to the *** atmospheric heating anomaly over the HMA thickens the atmospheric column and increases upper air *** high pressure anomaly disperses downstream via the westerly flow,expands across the SCB,and eventually increases the SCB *** effect lasts from winter to the following spring,which may cause the maximum increasing trend of the SCB temperature and vegetation coverage in *** results are helpful for estimating future trends in climate and eco-environmental variations in the HMA and SCB under warming scenarios,as well as seasonal forecasting based on the connection between the HMA eco-environment and SCB climate.

关键词： Hengduan Mountains Area normalized difference vegetation index climate change net heat flux downstream effects

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Structure,bioavailability and physicochemical properties of icariin-soymilk nanoparticle

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Food Science and Human Wellness 2024年第2期13卷 972-981页

作者： Jinping Wang Lingrong wen Yueming Jiang Hong Zhu Weizheng sun Guangyi Dai Bao Yang Guangdong Provincial Key Laboratory of Applied Botany Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic ImprovementSouth China Botanical GardenChinese Academy of SciencesGuangzhou 510650China South China National Botanical Garden Guangzhou 510650China College of Food Science and Engineering Jilin Agricultural UniversityChangchun 130118China University of Chinese Academy of Sciences Beijing 100049China School of Food Sciences and Engineering South China University of TechnologyGuangzhou 510640China

Soymilk is a natural ***,the performance of flavonoid-soymilk nano-complex remains *** this work,icariin-soymilk nano-complexes(ISNCs)were successfully fabricated and *** effects of high-pressure homogenization(HPH)treatment on structure and physicochemical properties of soymilk and nano-complexes were *** treatment could significantly improve the surface hydrophobicity and interfacial activity of *** soymilk with HPH treatment could significantly improve the water solubility(20 folds),thermal stability and bioavailability of *** highest encapsulation efficiency(93.28%),loading capacity(39.09μg/mg),ζ-potentia(absolute value,31.20 mV)and bioavailability(72.14%)were observed in HSI-200(200 bar of homogenization pressure).While HSI-500(500 bar of homogenization pressure)showed the smallest particle size(183.73 nm).ISNCs showed a rougher surface and an irregular lamellar structure with large amount of fine particles by using Cryo-SEM,suggesting that icariin was encapsulated in *** data supplied a novel strategy to improve the performance of icariin in functional foods.

关键词： Encapsulation efficiency Flavonoid High pressure homogenization Loading capacity Nano-complex

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Genus-specific secondary metabolome in Allokutzneria and Kibdelosporangium

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Synthetic and Systems Biotechnology 2024年第3期9卷 381-390页

作者： Man-Jing Ma wen-Chao Yu huai-Ying sun Bing-Cheng Dong Gang-Ao Hu Zhen-Yi Zhou Yi hua Buddha Bahadur Basnet Yan-Lei Yu Hong Wang Bin Wei College of Pharmaceutical Science&Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals Zhejiang Key Laboratory of GreenLow-Carbonand Efficient Development of Marine Fishery ResourcesZhejiang University of TechnologyHangzhou 310014China Central Department of Biotechnology Trihuvan UniversityKathmanduNepal

Rare actinomycete genera are highly recognized as a promising source of structurally diverse and bioactive natural *** these genera,Allokutzneria and Kibdelosporangium are two phylogenetically closely related and have been reported to encode some valuable biosynthetic enzymes and secondary ***,there is currently no relevant systematic research available to outline the linkage of genomic and metabolomics for specific secondary metabolites in these two promising *** this study,we first investi-gated the genus-specific secondary metabolic potential in Allokutzneria and Kibdelosporangium by comparing the diversity and novelty of their secondary metabolite biosynthetic gene clusters(BGCs).The specific secondary metabolites produced by two representative strains of these genera were comprehensively investigated using untargeted metabolomics *** findings unveiled that the majority(95.4%)of the gene cluster families(GCFs)encoded by Allokutzneria and Kibdelosporangium were genus-specific,including NRPS GCFs encoding *** untargeted metabolomics analysis revealed that the metabolic profiles of two representative strains exhibit extensive specificity,with the culture medium having a big impact on the metabolic ***,an MS-cluster featuring a series of hydroxamate-type siderophores was identified from Allokutzneria albata JCM 9917,with two of them,including a novel one(N-deoxy arthrobactin A),being experimentally *** present study offers valuable insights for the targeted discovery of genus-specific natural products from microorganisms.

关键词： Genus-specific secondary metabolism Allokutzneria Kibdelosporangium Genome mining Untargeted metabolomics Siderophore

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Ingredients-based Methodology and Fuzzy Logic Combined Short-Duration Heavy Rainfall Short-Range Forecasting:An Improved Scheme

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Journal of Tropical Meteorology 2024年第3期30卷 241-256页

作者： TIAN Fu-you XIA Kun sun Jian-hua ZHENG Yong-guang hua Shan National Meteorological Center Beijing100081 China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of Sciences(IAP/CAS)Beijing 100029 China Key Laboratory of Cloud-Precipitation Physics and Severe Storms(LACS) Institute of Atmospheric PhysicsChinese Academy of Sciences(IAP/CAS)Beijing 100029 China

Short-duration heavy rainfall(SHR),as delineated by the National Meteorological Center of the China Me-teorological Administration,is characterized by hourly rainfall amounts no less than 20.0 *** is one of the most common convective weather phenomena that can cause severe ***-range forecasting of SHR is an important part of operational severe weather *** the present study,an improved objective SHR forecasting scheme was developed by adopting the ingredients-based methodology and using the fuzzy logic *** 1.0°×1.0°National Centers for Environmental Prediction(NCEP)final analysis data and the ordinary rainfall(0.1-19.9 mm h-1)and SHR observational data from 411 stations were used in the improved *** best lifted index,the total precipitable water,the 925 hPa specific humidity(Q 925),and the 925 hPa divergence(DIV 925)were selected as predictors based on objective *** distributed membership functions of predictors were obtained based on relative frequency *** weights of predictors were also objectively *** with a typhoon SHR case and a spring SHR case show that the main possible areas could be captured by the improved *** of SHR forecasts within 96 hours with NCEP global forecasts 1.0°×1.0°data initiated at 08:00 Beijing Time during the warm seasons in 2015 show the results were improved from both deterministic and probabilistic *** study provides an objectively feasible choice for short-range guidance forecasts of *** scheme can be applied to other convective phenomena.

关键词： ingredients-based methodology fuzzy logic approach probability of short-duration heavy rainfall(SHR) improved forecasting scheme objectively obtained membership functions

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Deep insight of unique phase transition behaviors and mechanism in Zr_(2)Co-H isotope system with ultra-low equilibrium pressure

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Rare Metals 2024年第1期43卷 212-224页

作者： Yang Liu Pan-Pan Zhou Xue-Zhang Xiao Jia-Cheng Qi Jia-Peng Bi Tiao Ying Xing-wen Feng Yan Shi wen-hua Luo Li-Xin Chen State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Institute of Materials China Academy of Engineering PhysicsMianyang 621907China Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang Province Hangzhou 310013China

Efficient capture,safe storage and release of tritium from the international thermonuclear experimental reactor(ITER) reaction exhaust gas is a perplexing problem,and the development of an efficient tritium-getter material with ultra-low hydrogenation equilibrium pressure is considered as a reliable *** this work,Zr_(2)Co alloy was selected as a tritium-getter material and prepared through induction levitation *** performance test results show that Zr_(2)Co exhibits an ultra-low hydrogenation equilibrium pressure of 3.22 × 10^(-6) Pa at 25℃ and excellent hydriding kinetics under a low hydrogen pressure of 0.005 ***,unique phase transition behaviors were presented in Zr_(2)Co-H ***,Zr_(2)CoH_(5) formed by Zr_(2)Co hydrogenated at room temperature is initially decomposed into ZrH_(2) and ZrCoH_(3) at200 ℃.With the temperature increasing to 350 ℃,ZrCoH_(3)is dehydrogenated to ZrCo,and then ZrCo further reacts with ZrH_(2) at 650 ℃ to reform Zr_(2)Co and *** the staged phase transition pathways during dehydrogenation,the decomposition of Zr_(2)CoH_(5) occurs preferentially,which is well accordance with both the smallest reaction energy barrier and the maximum reaction spontaneity that are determined respectively from kinetics activation energy and thermodynamics Gibbs free ***,first principles calculation results indicate that the stronger binding of hydrogen in interstitial environments of ZrCoH_(3)and ZrH_(2) triggers the hydrogen-stabilized phase transformation of Zr_(2)CoH_(5).The unique phase transition mechanisms in Zr_(2)Co-H system can shed light on the further exploration and regulation of analogous staged phase transition of hydrogen storage materials.

关键词： Zr_(2)Co alloy Tritium-getter materials Ultralow equilibrium hydrogen pressure Phase transition mechanism

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Vibration-Based Fault Diagnosis for Railway Point Machines Using VMD and Multiscale Fluctuation-Based Dispersion Entropy

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Chinese Journal of Electronics 2024年第3期33卷 803-813页

作者： Yongkui sun Yuan CAO Peng LI Guo XIE Tao wen Shuai SU National Engineering Research Center of Rail Transportation Operation and Control System Beijing Jiaotong University School of Electronic and Information Engineering Beijing Jiaotong University Shaanxi Key Laboratory of Complex System Control and Intelligent Information Processing Xi'an University of Technology Frontiers Science Center for Smart High-speed Railway System Beijing Jiaotong University

As one of the most important railway signaling equipment,railway point machines undertake the major task of ensuring train operation *** fault diagnosis for railway point machines becomes a hot *** the advantage of the anti-interference characteristics of vibration signals,this paper proposes an novel intelligent fault diagnosis method for railway point machines based on vibration signals.A feature extraction method combining variational mode decomposition(VMD) and multiscale fluctuation-based dispersion entropy is developed,which is verified a more effective tool for feature ***,a two-stage feature selection method based on Fisher discrimination and ReliefF is proposed,which is validated more powerful than single feature selection ***,support vector machine is utilized for fault *** comparisons show that the proposed method performs *** diagnosis accuracies of normal-reverse and reverse-normal switching processes reach 100% and 96.57% ***,it is a try to use new means for fault diagnosis on railway point machines,which can also provide references for similar fields.

关键词： Fault diagnosis Vibrations Support vector machines Diversity reception Switches Feature extraction Rail transportation

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Loss of heterozygosity for chromosomes 16q in Wilms tumors predicts outcomes:A meta-analysis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2159-2167页

作者： Yuan-hua Song wen-Ling Li Zhen Yang Yan Gao Zhi-Ping Feng Department of Oncology Kunming Children's HospitalKunming 650103Yunnan ProvinceChina Department of Nuclear Medicine The Third Affiliated Hospital of Kunming Medical University(Yunnan Cancer Hospital)Kunming 650118Yunnan ProvinceChina

BACKGROUND The research findings suggest that the prognosis of children with Wilms tumor(WT)is affected by various *** scholars have indicated that loss of heterozygosity(LOH)on chromosome 16q is associated with a poor prognosis in patients with *** To further elucidate this relationship,we conducted a *** This meta-analysis was registered in INPLASY(INPLASY2023100060).We systematically searched databases including Embase,PubMed,Web of Science,Cochrane,and Google Scholar up to May 31,2020,for randomized trials reporting any intrapartum fetal surveillance *** meta-analysis was performed within a frequentist framework,and the quality and network inconsistency of trials were *** ratios and 95%CIs were calculated to report the relationship between event-free survival and 16q LOH in patients with *** Eleven cohort studies were included in this meta-analysis to estimate the relationship between event-free survival and 16q LOH in patients with WT(I^(2)=25%,P<0.001).As expected,16q LOH can serve as an effective predictor of eventfree survival in patients with WT(risk ratio=1.95,95%CI:1.52–2.49,P<0.001).CONCLUSION In pediatric patients with WT,there exists a partial correlation between 16q LOH and an unfavorable treatment *** detection of 16q chromosome LOH warrants increased attention to the patient’s prognosis.

关键词： Loss of heterozygosity Wilms tumor Survival time Chromosomes 16q

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ETHYLENE POLYMERIZATION PROMOTED WITH COMBINED CATALYSTS OF 8-AMINOQUINOLINE NICKEL DICHLORIDE AND Cp2ZrCl2

ETHYLENE POLYMERIZATION PROMOTED WITH COMBINED CATALYSTS OF ...

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International Symposium on Engineering Plastics EP’2001 Beijing

作者： Zilong Li Ning Zhu wen-hua sun Jiasong He Youliang Hu Xiuhua Li State Key Laboratory of Engineering Plastics and the Center for Molecular Science Institute of ChemistryThe Chinese Academy of Sciences

The synergic catalysis of oligomerization and polymerization catalysts in one catalytic system has become interesting topic for forming high-branched *** combination of early/late transition metal catalysts in ethylen...

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Shi-pi-xiao-ji formula suppresses hepatocellular carcinoma by reducing cellular stiffness through upregulation of acetyl-coA acetyltransferase 1

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2727-2741页

作者： Hui-Ying Jian Zi-Cheng Liang huan wen Zhen Zhang Pu-hua Zeng Graduate School Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Hunan Provincial Hospital of Integrated Traditional Chinese and Western Cancer Research Institute of Hunan Academy of Traditional Chinese MedicineHunan Academy of Chinese MedicineChangsha 410006Hunan ProvinceChina

BACKGROUND Previous studies have shown that the Shi-pi-xiao-ji(SPXJ)herbal decoction formula is effective in suppressing hepatocellular carcinoma(HCC),but the underlying mechanisms are not ***,this study investigated whether the antitumor effects of the SPXJ formula in treating HCC were mediated by acetyl-coA acetyltransferase 1(ACAT1)-regulated cellular *** a series of experiments,we concluded that SPXJ inhibits the progression of HCC by upregulating the expression level of ACAT1,lowering the level of cholesterol in the cell membrane,and altering the cellular stiffness,which provides a new idea for the research of traditional Chinese medicine against *** To investigate the anti-tumor effects of the SPXJ formula on the malignant progression of *** HCC cells were cultured in vitro with SPXJ-containing serum prepared by injecting SPXJ formula into wild-type *** apoptotic rate and proliferative,invasive,and migratory abilities of control and SPXJ-treated HCC cells were *** force microscopy was used to determine the cell surface morphology and the Young’s modulus values of the control and SPXJ-treated HCC *** membrane cholesterol levels in HCC cells were detected using the Amplex Red cholesterol detection ***1 protein levels were estimated using western *** Compared with the vehicle group,SPXJ serum considerably reduced proliferation of HCC cells,increased stiffness and apoptosis of HCC cells,inhibited migration and invasion of HCC cells,decreased plasma membrane cholesterol levels,and upregulated ACAT1 protein ***,treatment of HCC cells with the water-soluble cholesterol promoted proliferation,migration,and invasion of HCC cells as well as decreased cell stiffness and plasma membrane cholesterol levels,but did not alter the apoptotic rate and ACAT1 protein expression levels compared with the vehicle *** SPXJ formula inhibited proliferation,invasion,and migration

关键词： Shi-pi-xiao-ji formula Hepatocellular carcinoma Cellular stiffness Plasma membrane cholesterol level AcetylcoA acetyltransferase 1

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