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Science China Chemistry 2022年第10期65卷 1945-1952页

作者： Kun Yao zheng Liu Hang Li Dan Xu wen-hua zheng Yi-Wu Quan Yi-Xiang Cheng Jiangsu Key Laboratory of Advanced Organic Materials School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Key Laboratory of High Performance Polymer Material and Technology of Ministry of Education Department of Polymer Science and EngineeringSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

We report the rational design of a dual stimulus-activated quaternary chiral emission nematic liquid crystals(Q-N*-LCs)containing light-driven chiral dopant R-S-R-1,a static chiral dopant S-2 and an achiral Nile Red(NR)in a nematic liquid crystal(SLC1717).The dopant R-S-R-1 acts as a dynamic chiral donor and an energy donor,and the achiral NR serves as a circularly polarized luminescence(CPL)emitter and energy acceptor.Interestingly,this kind of Q-N*-LCs appears reversal CPL emission direction(L-CPL)using 365 nm UV light irradiation compared with the initial state(R-CPL).Most importantly,the“On-Off”CPL switch behavior of Q-N*-LCs can be repeatedly driven by revoking or rearranging the applied direct current(DC)electric field.An OR chiral information logic gate demonstrates that this dual driven Q-N*-LCs can be potentially used for chiral information storage and coding.

关键词： chiral supramolecular liquid crystals circularly polarized luminescence light and electricity dual stimuli-activated Förster resonance energy transfer

Experimental observation of spontaneous symmetry breaking in a quantum phase transition

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 34-39页

作者： wen Ning Ri-hua zheng Jia-Hao Lu Fan Wu Zhen-Biao Yang Shi-Biao zheng Fujian Key Laboratory of Quantum Information and Quantum Optics College of Physics and Information EngineeringFuzhou UniversityFuzhou 350108China Hefei National Laboratory Hefei 230088China

Spontaneous symmetry breaking(SSB)plays a central role in understanding a large variety of phenomena associated with phase transitions,such as superfluid and superconductivity.So far,the transition from a symmetric vacuum to a macroscopically ordered phase has been substantially explored.The process bridging these two distinct phases is critical to understanding how a classical world emerges from a quantum phase transition,but so far remains unexplored in experiment.We here report an experimental demonstration of such a process with a quantum Rabi model engineered with a superconducting circuit.We move the system from the normal phase to the superradiant phase featuring two symmetry-breaking field components,one of which is observed to emerge as the classical reality.The results demonstrate that the environment-induced decoherence plays a critical role in the SSB.

关键词： quantum phase transition Rabi model spontaneous symmetry breaking superconducting circuit Schrodinger cat states

Goal-Oriented Control Systems(GOCS):From HOW to WHAT

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 816-819页

作者： wen-hua Chen the Department of Aeronautical and Automotive Engineering Loughborough UniversityLeicestershireLE113TUU.K.

Brief:New control theory is required to underpin safe design and deployment of future highly automated systems to deal with uncertain environments and complicated tasks,enabled by AI and other advanced technologies.Goal-Oriented Control Systems offer potential to transform the control system design from currently instructing a control system how to perform a task to specifying what is to be achieved.

关键词： automated instru system

Small nucleolar RNA and its potential role in the oncogenesis and development of colorectal cancer

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World Journal of Gastroenterology 2024年第2期30卷 115-127页

作者： Yang-zheng Lan zheng Wu wen-Jia Chen Ze-Xuan Fang Xin-Ning Yu hua-Tao Wu Jing Liu The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

Small nucleolar RNAs(snoRNAs)represent a class of non-coding RNAs that play pivotal roles in post-transcriptional RNA processing and modification,thereby contributing significantly to the maintenance of cellular functions related to protein synthesis.SnoRNAs have been discovered to possess the ability to influence cell fate and alter disease progression,holding immense potential in controlling human diseases.It is suggested that the dysregulation of snoRNAs in cancer exhibits differential expression across various cancer types,stages,metastasis,treatment response and/or prognosis in patients.On the other hand,colorectal cancer(CRC),a prevalent malignancy of the digestive system,is characterized by high incidence and mortality rates,ranking as the third most common cancer type.Recent research indicates that snoRNA dysregulation is associated with CRC,as snoRNA expression significantly differs between normal and cancerous conditions.Consequently,assessing snoRNA expression level and function holds promise for the prognosis and diagnosis of CRC.Nevertheless,current comprehension of the potential roles of snoRNAs in CRC remains limited.This review offers a comprehensive survey of the aberrant regulation of snoRNAs in CRC,providing valuable insights into the discovery of novel biomarkers,therapeutic targets,and potential tools for the diagnosis and treatment of CRC and furnishing critical cues for advancing research into CRC and the judicious selection of therapeutic targets.

关键词： Small nucleolar RNAs Colorectal cancer Dysregulation Biomarker

Desymmetrization of 2-substituted 1,3-diols via Bronsted Acid Mediated Oxidative Cleavage of Benzylidene Acetal

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Desymmetrization of 2-substituted 1,3-diols via Bronsted Aci...

Intermittent sliding-lock-knot suture for limbal conjunctival autograft fixation in pterygium surgery:a technique note

手性中国2014学术研讨会

作者： wen-hua zheng State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringNanjing University

＜正＞Enantioselective desymmetrization of meso or prochiral compounds is one of the most important strategies in asymmetric catalysis.In particular,the desymmetrization of diols has captured much attention for providing access to important chiral alcohols,as well as a wide variety of valuable building blocks.Desymmetrization of 2-substituted-1,3-diol remains a formidable challenge because of the long distance of pro-stereogenic center with

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来源： cnki会议评论

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 838-844页

作者： Ling Zhang Run-hua Lyu Jing-Ru Wang wen-Jian Shi Feng zheng Ying-Ying Gao Department of Ophthalmology the Second Affiliated HospitalFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Neurosurgery the Second Affiliated HospitalFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

AIM:To report a technique used with intermittent slidinglock-knot(ISLK)fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent(RI)fixation.METHODS:Consecutive patients with primary pterygium who had undergone pterygium excision combined with limbal conjunctival autograft transplantation between March 2021 and March 2022 at our institute were retrospectively analyzed.Primary outcome measures were mean duration of surgery and suture removal,degree of conjunctival hyperemia on postoperative day 1,pain score at suture removal,postoperative symptoms at 6mo,including conjunctival hyperemia,foreign body sensation,and graft stability.RESULTS:Ninety-eight patients underwent monocular surgery and were divided into ISLK(51 eyes)and RI(47 eyes)groups according to the type of conjunctiva autograft fixation method planned.There was no significant difference in mean duration of surgery between the two groups(18.59±2.39min vs 18.15±2.20min,P=0.417);however,compared to the RI group,shorter suture removal times were observed in the ISLK group[0.58min(0.42-0.87)vs 3.00min(2.21-4.15),P<0.001].The degree of conjunctival hyperemia on postoperative day 1 was milder in the ISLK group(P<0.001).Pain scores at suture removal were lower in the ISLK group than in RI group[1(0-3)vs 2(1-4),P<0.001].Postoperative symptoms at 6mo were comparable between the groups(P=0.487),with no recurrence.CONCLUSION:ISLK is an innovative method for limbal conjunctival autograft fixation after pterygium excision.Compared to RI fixation,ISLK facilitates suture removal and reduces discomfort,with comparable surgery duration and less conjunctival hyperemia.

关键词： intermittent sliding-lock-knot fixation pterygium suture removal

Black hole evaporation and its remnants with the generalized uncertainty principle including a linear term

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Communications in Theoretical Physics 2024年第2期76卷 125-136页

作者： Bo Yu zheng-wen Long College of Physics Guizhou UniversityGuiyang550025China

In recent years,researchers have investigated the evaporation of Schwarzschild black holes using various forms of the generalized uncertainty principle(GUP),metric quantum correction,and noncommutative geometry,respectively.However,there are differences between the GUP correction and the other two methods in terms of describing the later stages of black hole evaporation.Furthermore,some studies argue that the GUP with a negative parameter cannot effectively correct black hole evaporation,while others contend that the positivity or negativity of the GUP parameters should not affect the correction results.Taking the above into consideration,we reconsider black hole evaporation with the generalized uncertainty principle including a linear term(LGUP),and examine the case of negative parameters.The results indicate that the evaporation behavior of both Schwarzschild black holes and Reissner–Nordstr?m black holes,under LGUP correction,is consistent with the results of metric quantum correction and non-commutative geometry.Additionally,the negative parameter LGUP can also effectively correct for black hole evaporation.

关键词： black hole evaporation generalized uncertainty principle negative parameter

Effect of Pre-strain on Microstructure and Stamping Performance of High-strength Low-alloy Steel

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 774-780页

作者：刘坡 wen Zhicheng LIU zheng 许峰 School of Mechanical Engineering Guilin University of Aerospace TechnologyGuilin 541004China School of Automotive Engineer-ing Changshu Institute of TechnologyChangshu 215500China

In this study,pre-strain ranging from 0 to 0.12 was applied through uniaxial tension on high-strength low-alloy(HSLA)specimens with four kinds of grain size.Effect of pre-strain and grain size on me-chanical property was investigated through tensile tests.Microstructures of the pre-strained and tensile tested samples were analyzed,respectively.The 30.8°v-bending and following flattening,as well as Erichson cupping tests,were performed on the pre-strained samples.Results show the elongation ratio of grain and dislocation density increases with pre-strain.Yielding platform is removed when pre-strain is larger than 0.06 while yielding plateau period decreases with pre-strain less than 0.06 due to reduction of pinning effect.The 30.8°v-bending and the following flattening tests are successfully accomplished on all the pre-strained samples with different grain size.Decrease in grain size,along with increase in pre-strain,causes increase in strength and decrease in elongation rate as well as cupping value.Pre-strain causes very slight effect on bending ability,much less than that on mechanical property and cupping test value.Reciprocal impact of the pre-strain and grain size on HSLA steel deformability is inconspicuous.

关键词： strain hardening dislocation texture bending erichson cupping test

Advances of biomarkers in nasopharyngeal carcinoma’s early detection

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Science Bulletin 2024年第2期69卷 141-145页

作者： Xiao-Hui zheng Allan Hildesheim Wei-hua Jia State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510060China Costa Rican Agency for Biomedical Investigation INCIENSA FoundationSan Jose 10108Costa Rica

Nasopharyngeal carcinoma(NPC),a highly invasive and metastatic cancer,is widely prevalent in South China,Southeast Asia,and North Africa.NPC patients with stages I and II are often asymptomatic.Therefore,NPC patients are usually diagnosed with advanced-stage(stages III and IV)at their first visit.Detection of NPC at early stage is the key to improve the survival of patients.Epstein-Barr virus(EBV)plays an essential role in NPC occurrence in endemic areas.EBV-based biomarkers,including EBV antibody in serum and EBV DNA in plasma,have been specifically proposed for NPC early detection.Herein,we summarize recent advances in biomarkers for the early detection of NPC.

关键词： patients nasopharyngeal Nasopharyngeal

Exotic Localized Coherent Structures of New (2+1)-Dimensional Soliton Equation

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Communications in Theoretical Physics 2002年第11期38卷 517-522页

作者： ZHANG Jie-Fang huaNG wen-hua zheng Chun-Long Institute of Nonlinear Physics Zhejiang Normal University Jinhua 321004 China Institute of Nonlinear Physics Zhejiang Normal University Jinhua 321004 China Department of Physics Jiangxi Yichun University Yichun 336000 China Institute of Nonlinear Physics Zhejiang Normal University Jinhua 321004 China Department of Physics Zhejiang Lishui Normal College Lishui 323000 China

The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryfunctions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types ofsolutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functionsappropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the numberof the peaks.

关键词： variable separation approach, coherent structures, new (2+1)-dimensional soliton equation