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基于物理信息神经网络的盾构隧道诱发地表沉降预测

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工程力学 2024年第4期41卷 161-173页

作者：张子龙潘秋景仉文岗黄阜中南大学土木工程学院湖南长沙410075 中南大学隧地工程研究中心湖南长沙410075 重庆大学土木工程学院重庆400045 长沙理工大学土木工程学院湖南长沙410004

地表沉降是城市复杂环境下盾构隧道施工重点关注的问题。传统机器学习方法在预测隧道施工诱发地表沉降时忽略了其内在的物理机理,存在对训练样本需求量较大的弊端。基于深度神经网络(deep neural networks, DNN)对Verruijt-Booker解的... 详细信息

地表沉降是城市复杂环境下盾构隧道施工重点关注的问题。传统机器学习方法在预测隧道施工诱发地表沉降时忽略了其内在的物理机理,存在对训练样本需求量较大的弊端。基于深度神经网络(deep neural networks, DNN)对Verruijt-Booker解的围岩位移因子进行修正,构建地表沉降与隧道开挖面空间位置的关联。将修正后的Verruijt-Booker解的物理方程耦合至另一并行的DNN框架中,构建数据-物理双驱动的物理信息神经网络模型(physics-informed neural networks, PINN),从而约束神经网络在满足物理机制的空间中进行训练。算例分析的结果表明:在同等配置的条件下,提出的PINN模型的预测效果显著优于单一数据驱动的传统DNN模型,其外推泛化性能得到显著提升。工程应用的结果表明:PINN模型可以利用施工前期的实测数据,准确预测后续施工过程中开挖面在不同位置时监测断面的地表沉降值。提出的方法有助于提高盾构隧道施工过程中地表沉降控制的智慧化程度,可为工程的潜在风险及施工决策提供预警和指导。

关键词：盾构隧道地表沉降物理信息神经网络物理机理数据物理双驱动

Effectiveness and Safety of Qishen Yiqi Dripping Pill in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention:3-Year Results from a Multicentre Cohort Study

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Chinese Journal of Integrative Medicine 2024年第10期30卷 877-885页

作者： BAI Rui-na GU Feng CHE Qian-zi ZHANG Xuan CAI Ya-jie XI Rui-xi ZHAO Yang GUO Ming DONG Guo-ju GAO Zhu-ye fu Chang-geng WANG Pei-li DU Jian-peng ZHANG Da-wu DUAN wen-hui LI Li-zhi YANG Qiao-ning SHI Da-zhuo Department of Cardiovascular Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China National Clinical Research Center for Chinese Medicine Cardiology Beijing100091China Department of Evidence-Based Medicine Basic Research Laboratory Institute of Basic Research in Clinical MedicineChina Academy of Chinese Medical SciencesBeijing100700China Department of Traditional Chinese Medicine Beijing Shangdi HospitalBeijing100193China National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Traditional Chinese MedicineBeijing100091China

Objectives:To evaluate the effectiveness and safety of Qishen Yiqi Dripping Pill(QSYQ)in patients with acute coronary syndrome(ACS)after percutaneous coronary intervention(PCI).Methods:This multicentre prospective cohort study was conducted at 40 centers in *** with ACS after PCI entered either the QSYQ or Western medicine(WM)groups naturally based on whether they had received QSYQ before *** group received QSYQ(0.52.g,3 times a day for 12.months)in addition to *** primary endpoint included cardiac death,non-fatal myocardial infarction,and urgent *** secondary endpoint included rehospitalization due to ACS,heart failure,stroke,and other thrombotic *** of life was assessed by the Seattle Angina Questionnaire(SAQ).Results:A total of 936 patients completed follow-up of the primary endpoint from February 2.12.to December ***,487 patients received QSYQ and *** a median follow-up of 566 days(inter quartile range,IQR,517–602.,the primary endpoint occurred in 46(9.45%)and 65(14.48%)patients in QSYQ and WM groups respectively[adjusted hazard ratio(HR)0.60,95%confidence interval(CI)0.41–0.90;P=0.013].The secondary endpoint occurred in 61(12.53%)and 74(16.48%)patients in QSYQ and WM groups,respectively(adjusted HR 0.76,95%CI 0.53–1.09;P=0.136).In sensitivity analysis,the results still demonstrated that WM combined with QSYQ reduced the risk of the primary endpoint(HR 0.67,95%CI 0.46–0.98;P=0.039).Moreover,QSYQ improved the disease perception domain of the SAQ(P2..

关键词： Qishen Yiqi Dripping Pill acute coronary syndrome percutaneous coronary intervention primary and secondary endpoint

Review of the potential value of serum interleukin levels as prognostic biomarkers of liver failure

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World Journal of Clinical Cases 2024年第27期12卷 6045-6056页

作者： Yong Lin Geng-Jie Yan Mei-Yan Liu Yin Cao Kan Zhang Na Wang fu-Li Long De-wen Mao Graduate School Guangxi University of Chinese MedicineNanning 530200Guangxi Zhuang Autonomous RegionChina Guangxi School of Chinese Medicine Guangxi University of Traditional Chinese MedicineNanning 530022Guangxi Zhuang Autonomous RegionChina Department of Hepatology The First Affiliated Hospital of Guangxi University of Chinese MedicineNanning 530023Guangxi Zhuang Autonomous RegionChina Department of Administration The First Affiliated Hospital of Guangxi University of Chinese MedicineNanning 530023Guangxi Zhuang Autonomous RegionChina

Liver failure(LF)is prevalent in China and is characterized by complex path-ogenesis,challenging clinical management,poor prognosis,and rising incidence and mortality *** immune status is an important factor affecting LF ***(Ils)are a type of cytokine that act and interact with multiple cells,including immune *** signaling molecules play important roles in intercellular information transmission,including the regulation of immune cells;mediation of the activation,proliferation,and differentiation of T and B cells;and orchestration of the inflammatory *** date,many studies have explored the correlation between IL expression and liver disease prognosis,but few studies have evaluated Ils as the prognostic biomarkers of *** article reviews the potential use of Ils as the prognostic biomarkers of ***,it evaluates the predictive values of IL-2.,IL-2.,and IL-31,the three often overlooked yet promising prognostic biomarkers,in predicting suscept-ibility to *** biomarkers for early prognostic insights can facilitate tailored treatment strategies and enhance patient ***,this article focuses on the identification of IL-2.,IL-2.,and IL-33 as biomarkers in preclinical and clinical studies on LF and reviews their role as biomarkers in the pathogenesis and diagnosis of LF.

关键词： Interleukin-2. Interleukin-2. Interleukin-31 Liver failure Biological markers Potential value

Naoxueshu Oral Liquid Accelerates Post-Craniotomy Hematoma Absorption in Patients:An Open-Label,Multicenter,and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第8期30卷 675-683页

作者： HE Qiu LIN fu-xin SU Jin-ye ZHUO Ling-yun ZHU Qing SUN Xiao-chuan JIANG Rong-cai YAO Zhi-gang WANG Lei DANG Yan-wei LIU De-zhong LIU Yang FANG wen-hua WANG Fang-yu LIN Yuan-xiang WANG An-xin WANG Deng-liang KANG De-zhi Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou350209China Clinical Research and Translation Center The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China fujian Clinical Research Center for Neurological Diseases The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China fujian Provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Department of Neurosurgery The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu Province215000China Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing400000China Department of Neurosurgery Tianjin Medical University General HospitalTianjin300000China Department of Neurosurgery The Third Hospital of ShijiazhuangShijiazhuang050000China Department of Neurosurgery The First College of Clinical Medical ScienceChina Three Gorges UniversityYichangHubei Province443000China Department of Neurosurgery Yichang Central People’s HospitalYichangHubei Province443000China Department of Neurosurgery Xiangyang No.1 People’s Hospital Affiliated to Hubei University of MedicineXiangfanHubei Province441100China Department of Neurosurgery Zhoukou Central HospitalZhoukouHenan Province466000China Department of Neurosurgery The Third Hospital of MianyangMianyangSichuan Province621000China Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing100000China China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijing100000China Department of Clinical Epidemiology and Clinical Trial Capital Medical UniversityBeijing100000China Beijing Municipal Key Laboratory of Clinical

Objective: To investigate whether Naoxueshu Oral Liquid(NXS) could promote hematoma absorption in post-craniotomy hematoma(PCH) patients. Methods: This is an open-label, multicenter, and randomized controlled trial conducted at 9 hospitals in China. Patients aged 18–80 years with post-craniotomy supratentorial hematoma volume ranging from 10 to 30 mL or post-craniotomy infratentorial hematoma volume less than 10 mL, or intraventricular hemorrhage following cranial surgery were enrolled. They were randomly assigned at a 1:1 ratio to the NXS(10 m L thrice daily for 15 days) or control groups using a randomization code table. Standard medical care was administered in both groups. The primary outcome was the percentage reduction in hematoma volume from day 1 to day 15. The secondary outcomes included the percentage reduction in hematoma volume from day 1 to day 7, the absolute reduction in hematoma volume from day 1 to day 7 and 15, and the change in neurological function from day 1 to day 7 and 15. The safety was closely monitored throughout the study. Moreover, subgroup analysis was performed based on age, gender, history of diabetes, and etiology of intracerebral hemorrhage(ICH). Results: A total of 12. patients were enrolled and randomly assigned between March 30, 2.18 and April 15, 2.2.. One patient was lost to follow-up in the control group. Finally, there were 119 patients(60 in the NXS group and 59 in the control group) included in the analysis. In the full analysis set(FAS) analysis, the NXS group had a greater percentage reduction in hematoma volume from day 1 to day 15 than the control group [median(Q1, Q3): 85%(71%, 97%) vs. 76%(53%, 93%), P0.05). furthermore, no adverse events were reported during the study. In the FAS analysis, the NXS group exhibited a higher percentage reduction in hematoma volume on day 15 in the following subgroups:

关键词： post-craniotomy hematoma Naoxueshu Oral Liquid hematoma absorption randomized controlled trial Chinese medicine

Atom-referenced and stabilized soliton microcomb

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 2-8页

作者： Rui Niu Shuai Wan Tian-Peng Hua Wei-Qiang Wang Zheng-Yu Wang Jin Li Zhu-Bo Wang Ming Li Zhen Shen Yu Robert Sun Shui-Ming Hu Brent ELittle Sai Tak Chu Wei Zhao Guang-Can Guo Chang-Ling Zou Yun-Feng Xiao wen-fu Zhang Chun-Hua Dong State Key Laboratory of Transient Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China University of Chinese Academy of Sciences Beijing 100049China Department of Chemical Physics University of Science and Technology of ChinaHefei 230026China Department of Physics and Materials Science City University of Hong KongHong Kong 999077China State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China

For the applications of the frequency comb in microresonators,it is essential to obtain a fully frequency-stabilized microcomb laser *** this study,we present a system for generating a fully atom-referenced stabilized soliton *** pump light around 1560.48 nm is locked to an ultra-low-expansion(ULE)*** pump light is then frequency-doubled and referenced to the atomic transition *** repetition rate of the soliton microcomb is injection-locked to an atomic-clockstabilized radio frequency(RF)source,leading to mHz stabilization at 1 *** a result,all comb lines have been frequencystabilized based on the atomic reference and the ULE cavity,achieving a very high precision of approximately 18 Hz at 1 s,corresponding to the frequency stability of 9.5×10^(-14).Our approach provides a fully stabilized microcomb experiment scheme with no requirement of f-2. technique,which could be easily implemented and generalized to various photonic platforms,thus paving the way towards the ultraprecise optical sources for high precision spectroscopy.

关键词： microcavity frequency comb dissipative Kerr solitons fully stabilized microcomb

Sinonasal teratocarcinosarcoma involving the nasal cavity,unilateral paranasal sinuses,and intracranial invasion:A case report

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World Journal of Clinical Cases 2024年第25期12卷 5784-5790页

作者： Li-Yuan fu Mi-Yang Yang Pei-Yun Ye Zhao-Chu Wang Chu-Jie Chen Hui Li Shang-wen Xu Department of Radiology 900th Hospital of Joint Logistics Support ForceFuzhou 350025Fujian ProvinceChina The First Clinical Medical College Fuzong Teaching HospitalFujian University of Traditional Chinese MedicineFuzhou 350122Fujian ProvinceChina

BACKGROUND Sinonasal teratocarcinosarcoma(SNTCS)is a rare and highly invasive neoplasm originating from the nasal cavity and ***,it exhibits an invasive behavior towards adjacent structures;however,in exceptional instances,it may infiltrate the intracranial *** to the tumor's rarity and lack of distinctive features on computed tomography(CT)and magnetic resonance imaging(MRI)images,SNTCS is often *** SUMMARY In this study,we present a case of SNTCS in a 56-year-old patient who exhibited unexplained cognitive impairment before *** and MRI scans revealed the presence of a mass in the right nasal cavity,with lesions extending to the right ethmoid sinus and right frontal ***,the patient underwent pathological examination for confirmation and received surgical intervention to excise the *** future advancement in our understanding of this disease will significantly contribute to the precise diagnosis and treatment of *** SNTCS is an exceptionally rare malignant tumor that originates from the nasal cavity and paranasal sinuses,presenting a diagnostic challenge due to its nonspecific imaging *** accurately delineates the location,morphological characteristics,size,internal structure,extent of surrounding involvement,and metabolic information of the *** aspects play a pivotal role in the precise localization and qualitative assessment of ***,a definitive diagnosis still requires a pathological biopsy.

关键词： Paranasal sinus Malignant tumor Sinonasal teratocarcinosarcoma Brain invasion Case report

网络使用非适应性认知对大学生抑郁的影响:网络风险行为和网络受欺负的链式中介作用

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中国临床心理学杂志 2024年第4期32卷 831-836页

作者：丘文福叶一舵福建师范大学心理学院福州350117 福建师范大学心理健康指导中心福州350117

目的:探究网络使用非适应性认知对大学生抑郁的影响,以及网络风险行为和网络受欺负在二者之间的中介作用。方法:采用网络使用非适应性认知问卷、网络风险行为量表、网络受欺负问卷和抑郁量表对1076名大学生进行调查。结果:(1)网络使用... 详细信息

目的:探究网络使用非适应性认知对大学生抑郁的影响,以及网络风险行为和网络受欺负在二者之间的中介作用。方法:采用网络使用非适应性认知问卷、网络风险行为量表、网络受欺负问卷和抑郁量表对1076名大学生进行调查。结果:(1)网络使用非适应性认知显著正向预测大学生的抑郁;(2.网络风险行为和网络受欺负在大学生的网络使用非适应性认知与抑郁之间均起部分中介作用;(3)网络风险行为和网络受欺负在大学生的网络使用非适应性认知与抑郁之间起链式中介作用。结论:网络使用非适应性认知可通过网络风险行为和网络受欺负显著正向预测大学生的抑郁。

关键词：网络使用非适应性认知网络风险行为网络受欺负抑郁

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基于多引导结构感知网络的深度补全

控制与决策 2024年第2期39卷 401-410页

作者：孙虎金宇强张文安付明磊浙江工业大学信息工程学院杭州310023 浙江省嵌入式系统联合重点实验室杭州310023

针对三维场景深度信息观测稀疏问题,提出一种融合彩色图像的多引导结构感知网络模型以补全稀疏深度.首先,利用三维平面法向量与场景梯度信息之间的映射关系,设计一种两分支主干网络框架,结合图像特征和几何特征进行深度预测,以充分提取... 详细信息

针对三维场景深度信息观测稀疏问题,提出一种融合彩色图像的多引导结构感知网络模型以补全稀疏深度.首先,利用三维平面法向量与场景梯度信息之间的映射关系,设计一种两分支主干网络框架,结合图像特征和几何特征进行深度预测,以充分提取空间位置信息的特征表示;然后,考虑到大范围场景下不同物体的结构差异性,基于网络通道注意力机制设计一种自适应感受野的结构感知模块,以对不同尺度的信息进行表征;最后,在网络采样的过程中,以不同尺寸图像为指导对预测子深度图进行滤波并修复物体的边缘细节.公开数据集上的实验结果表明,所设计的深度补全算法可以获得准确的稠密深度,同时通过两个下游感知任务进行深入评估,表明利用所提出方法能够有效提升其他感知任务的效果.

关键词：稀疏场景深度补全结构感知多传感器融合图像引导滤波自适应感受野

结合全局信息增强的医学领域命名实体识别研究

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电子科技大学学报 2024年第3期53卷 431-439页

作者：要媛媛付潇杨东瑛王洁宁郑文太原理工大学计算机科学与技术学院(大数据学院) 晋中030600 中国船舶集团有限公司综合技术经济研究院北京100081 长治医学院山西省智能数据辅助诊疗工程研究中心长治046000

中文医疗问诊文本中,由于口语化的不规则表达和专业术语的频繁出现,药物名称等实体难以被精准地识别出来。为了充分利用中文句子词间关系的重要作用,提出了一种用于增强全局信息的医学命名实体识别模型。模型利用注意力机制增强了词嵌... 详细信息

中文医疗问诊文本中,由于口语化的不规则表达和专业术语的频繁出现,药物名称等实体难以被精准地识别出来。为了充分利用中文句子词间关系的重要作用,提出了一种用于增强全局信息的医学命名实体识别模型。模型利用注意力机制增强了词嵌入表征,并在使用双向长短时记忆网络的序列处理能力获取上下文信息的基础上,同时从两个方面丰富了句子的全局信息表示。其一是根据句法关系获取词语之间额外依赖关系构建了图卷积网络层用于丰富词间的依赖;其二是构建了辅助任务用于预测词间句法依赖关系的类别。在中文医疗问诊数据集上的实验结果表明,模型具有很好的竞争力,F1值达到94.54%。与其他模型相比,在药物和症状等实体类别的识别上取得了明显提高。在微博公开数据集上的实验也表明,模型具有通用领域的应用价值。

关键词：注意力机制双向长短时记忆网络图卷积网络医疗问诊命名实体识别