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Corrugated Graphene Paper Reinforced Silicone Resin Composite for Efficient Interface Thermal Management

Chinese Journal of Polymer Science 2024年第7期42卷 1002-1014,I0010页

作者： bo-wen wang Heng Zhang Qing-Xia He Hui-Tao Yu Meng-Meng Qin Wei Feng Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin300350China International Engineering Institute Tianjin UniversityTianjin300350China

With the rapid development of high-power-density electronic devices,interface thermal resistance has become a critical barrier for effective heat management in high-performance electronic ***,there is an urgent demand for advanced thermal interface materials(TIMs)with high cross-plane thermal conductivity and excellent compressibility to withstand increasingly complex operating *** achieve this aim,a promising strategy involves vertically arranging highly thermoconductive graphene on ***,with the currently available methods,achieving a balance between low interfacial thermal resistance,bidirectional high thermal conductivity,and large-scale production is ***,we prepared a graphene framework with continuous filler structures in in-plane and cross-plane directions by bonding corrugated graphene to planar graphene *** interface interaction between the graphene paper framework and polymer matrix was enhanced via surface functionalization to reduce the interface thermal *** resulting three-dimensional thermal framework endows the polymer composite material with a cross-plane thermal conductivity of 14.4 W·m^(-1)·K^(-1)and in-plane thermal conductivity of 130W·m^(-1)·K^(-1)when the thermal filler loading is 10.1 wt%,with a thermal conductivity enhancement per 1 wt%filler loading of 831%,outperforming various graphene structures as *** its high thermal conductivity,low contact thermal resistance,and low compressive modulus,the developed highly thermoconductive composite material demonstrates superior performance in TIM testing compared with TFLEX-700,an advanced commercial TIM,effectively solving the interfacial heat transfer issues in electronic *** novel filler structure framework also provides a solution for achieving a balance between efficient thermal management and ease of processing.

关键词： Graphene paper Vertically aligned structure Cross-plane thermal conductivity Low compressive modulus Thermal interface material

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Visualization of ferromagnetic domains in vanadium-doped topological insulator thin films and heterostructures

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钨科技(英文) 2023年第3期5卷 288-299页

作者： Ying-Jie Ma Ti-Rui Xia wen-bo wang School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China ShanghaiTech Laboratory for Topological Physics ShanghaiTech UniversityShanghai 201210China

Magnetically doped topological insulator(TI) thin films and related heterostructures have been extensively studied for years due to their exotic quantum transport properties and potential applications in low-dissipation electronic devices and quantum *** selection of magnetic dopants is crucial to realize a high-quality magnetic TI with a robust ferromagnetic ordering and a preserved topological band *** this paper,we briefly review the recent magnetic domain imaging works in vanadium-doped magnetic topological insulator thin films and *** cryogenic magnetic force microscopy and in situ transport measurements,a ferromagnetic domain behavior has been demonstrated in V-doped Sb2Te3(ST) and Cr,V co-doped(Bi,Sb)2Te3(BST) thin *** direct visualization of long-range ferromagnetic ordering in a quantum anomalous Hall(QAH) system sheds light on enhancing the QAH temperature by improving the *** advantage of the different coercivity of Cr-and V-doped BST films,an axion insulating state has been observed in Cr-doped BST/BST/V-doped BST sandwich *** antiparallel magnetization alignment,which is the key ingredient for realization of axion insulating state,has been directly visualized via magnetic imaging at various magnetic *** V-doped ST/ST heterostructures also provide a platform for Berry phase engineering in momentum *** suppressing the anomalous Hall effect in such heterostructures,an intrinsic topological Hall effect can be revealed,which resolved the long-term puzzle of the origin of THE in the ultrathin ferromagnetic thin films and two-dimensional *** review of magnetic domain imaging in vanadium-doped topological insulators and heterostructures inspires further exploration of quantum transport properties in magnetic topological insulators and deepens the understanding of the interplay between the magnetic ordering and topological electronic band structures in magne

关键词： Vanadium-doped topological insulator Magnetic force microscopy Ferromagnetic domain Quantum anomalous Hall effect Topological Hall effect

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Effect of Physical Aging on Heterogeneity of Poly(ε-caprolactone)Toughening Poly(lactic acid)Probed by Nanomechanical Mapping

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高分子科学：英文版 2023年第1期41卷 143-152页

作者： bo-wen wang Hao Liu Jin Ying Chun-Tai Liu Chang-Yu Shen Ya-Ming wang Key Laboratory of Materials Processing&Mold(Zhengzhou University) Ministry of EducationNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou450002China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou450001China

Poly(lactic acid) (PLA) is a promising bio-based environmentally-friendly plastic. Nevertheless, the physical aging-induced brittleness of PLA limits its widespread applications. Blending with immiscible ductile polymer is an effective way to toughen PLA. However, the underlying details of the toughening mechanism and, in particular, the effect of physical aging are not well understood. Herein, atomic force microscopy (AFM) based nanomechanical mapping technology was utilized to visualize the differences in the deformation mechanisms between unaged and aged PLA/poly(ε-caprolactone) (PCL) blend upon uniaxial drawing. Results show that physical aging has a significant effect on the microscopic Young’s modulus and its distribution of PLA matrix, resulting in a highly heterogeneous response of the PLA/PCL blend to external stress and affecting the mechanical properties of the PLA phase under different extensions. This work provides a new experimental basis for understanding the effect of physical aging on the mechanical properties of PLA-based materials.

关键词： Poly(lactic acid) Blends Toughening Physical aging Nanomechanical mapping

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Model-based deep learning for fiber bundle infrared image restoration

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Defence Technology(防务技术) 2023年第9期27卷 38-45页

作者： bo-wen wang Le Li Hai-bo Yang Jia-xin Chen Yu-hai Li Qian Chen Chao Zuo Jiangsu Key Laboratory of Spectral Imaging and Intelligent Sense Nanjing University of Science and TechnologyNanjingJiangsu Province210094China Smart Computational Imaging(SCI)Laboratory Nanjing University of Science and TechnologyNanjingJiangsu Province210094China Science and Technology on Electro-Optical Information Security Control Lab Tianjin300308China

As the representative of flexibility in optical imaging media,in recent years,fiber bundles have emerged as a promising architecture in the development of compact visual *** to tackling the problems of universal honeycomb artifacts and low signal-to-noise ratio(SNR)imaging in fiber bundles,the iterative super-resolution reconstruction network based on a physical model is *** the constraint of solving the two subproblems of data fidelity and prior regularization term alternately,the network can efficiently“regenerate”the lost spatial resolution with deep *** building and calibrating a dual-path imaging system,the real-world dataset where paired low-resolution(LR)-high-resolution(HR)images on the same scene can be generated *** results on both the United States Air Force(USAF)resolution target and complex target objects demonstrate that the algorithm can restore high-contrast images without pixilated *** the basis of super-resolution reconstruction,compound eye image composition based on fiber bundle is also embedded in this paper for the actual imaging *** proposed work is the first to apply a physical model-based deep learning network to fiber bundle imaging in the infrared band,effectively promoting the engineering application of thermal radiation detection.

关键词： Fiber bundle Deep learning Infrared imaging Image restoration

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Immune checkpoint inhibitor therapy-induced autoimmune polyendocrine syndrome typeⅡand Crohn's disease:A case report

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World Journal of Clinical Cases 2023年第14期11卷 3267-3274页

作者： Mei-Juan Gao Yan Xu wen-bo wang Department of Endocrinology Peking University Shougang HospitalBeijing 100041China

BACKGROUND The development of immune checkpoint inhibitors(ICIs)has heralded a new era in cancer treatment,enabling the possibility of long-term survival in patients with metastatic ***,ICIs are increasingly implicated in the development of autoimmune *** SUMMARY We present a man with squamous cell carcinoma of the oropharynx on a combination of teriprizumab,docetaxel,and cisplatin therapy who developed autoimmune polyendocrine syndrome typeⅡ(APS-2)including thyroiditis and type 1 diabetes mellitus and Crohn’s disease(CD).He developed thirst,abdominal pain,and fatigue after two-week treatment with the protein 1 ligand inhibitor *** confirmed APS-2 and *** was commenced on an insulin ***,his abdominal pain ***-up surgery confirmed CD and his abdominal pain was relieved by *** was continued on insulin and mesalazine *** Immunotherapy can affect all kinds of *** clinical symptoms cannot be explained by a single disease,clinicians should consider the possibility of multisystem damage.

关键词： Immune checkpoint inhibitor Programmed cell death protein 1 ligand Autoimmune polyendocrine syndrome type II Type 1 diabetes mellitus Thyroiditis Crohn’s disease Case report

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Enrichment of anammox biomass during mainstream wastewater treatment driven by achievement of partial denitrification through the addition of bio-carriers

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Journal of Environmental Sciences 2024年第3期137卷 181-194页

作者： Yuqing Ma bo wang Xiaodi Li Shuo wang wen wang Yongzhen Peng National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology Engineering Research Center of BeijingBeijing University of TechnologyBeijing 100124China

Anammox is widely considered as the most cost-effective and sustainable process for nitrogen ***,how to achieve the enrichment of anammox biomass remains a challenge for its large-scale application,especially in mainstream wastewater *** this study,the feasibility of enrichment of anammox biomass was explored through the realization of partial denitrification and the addition of *** using ordinary activated sludge,a sequencing batch reactor(SBR)followed by an up-fow anaerobic sludge bed(UASB)was operated at 25±2℃ for 214 *** long-term operation was divided into five phases,in which SBR and UASB were started-up in Phases I and II,*** eliminating oxygen and adjusting the infow ratios in Phases III-V,advanced nitrogen removal was achieved with the effuent total nitrogen being 4.7 mg/L and the nitrogen removal efficiency being 90.5%in Phase *** in-situ and ex-situ activity tests demonstrated the occurrence of partial denitrification and ***,16S rRNA high-throughput sequencing analysis revealed that Candidatus Brocadia was enriched from below the detection limit to in biofilms(0.4%in SBR,2.2%in UASB)and the foc sludge(0.2%in SBR,1.3%in UASB),while Thauera was mainly detected in the foc sludge(8.1%in SBR,8.8%in UASB),which might play a key role in partial ***,this study provides a novel strategy to enrich anammox biomass driven by rapid achievement of partial denitrification through the addition of bio-carriers,which will improve large-scale application of anammox processes in mainstream wastewater treatment.

关键词： Enrichment Anammox biomass Bio-carriers Partial denitrification Mainstream wastewater

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Genome-wide analysis of the B3 transcription factors reveals that RcABI3/VP1 subfamily plays important roles in seed development and oil storage in castor bean(Ricinus communis)

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Plant Diversity 2022年第2期44卷 201-212页

作者： wen-bo wang Tao Ao Yan-Yu Zhang Di Wu Wei Xu Bing Han Ai-Zhong Liu Sino-Danish College University of Chinese Academy of SciencesBeijing100049China Northwest A&F University Yangling712100China Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China(Ministry of Education) Southwest Forestry UniversityKunming650224China Key Laboratory of Tropical Plant Resources and Sustainable Use Xishuangbanna Tropical Botanical GardenChinese Academy of ScienceMengla666303China Kunming Institute of botany Chinese Academy of Sciences132 Lanhei RoadKunming650204China University of Chinese Academy of Sciences Beijing100101China

The B3 transcription factors(TFs)in plants play vital roles in numerous biological *** B3 genes have been broadly identified in many plants,little is known about their potential functions in mediating seed development and material *** bean(Ricinus communis)is a non-edible oilseed crop considered an ideal model system for seed biology ***,we identified a total of 61 B3 genes in the castor bean genome,which can be classified into five subfamilies,including ABI3/VP1,HSI,ARF,RAV and *** expression profiles revealed that RcABI3/VP1 subfamily genes are significantly up-regulated in the middle and later stages of seed development,indicating that these genes may be associated with the accumulation of storage ***,through yeast one-hybrid and tobacco transient expression assays,we detected that ABI3/VP1 subfamily member RcLEC2 directly regulates the transcription of RcOleosin2,which encodes an oil-body structural *** finding suggests that RcLEC2,as a seed-specific TF,may be involved in the regulation of storage materials *** study provides novel insights into the potential roles and molecular basis of B3 family proteins in seed development and material accumulation.

关键词： B3 transcription factor Castor bean Gene expression ABI3/VP1 subfamily Seed development Seed oil

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BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF

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Nuclear Science and Techniques 2024年第7期35卷 68-78页

作者： Zhi-Jun wang Si-Sheng wang Zheng-Huang Su Li Yu Yu-Zhu wang bo Sun wen wen Xing-Yu Gao Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai201210China University of Chinese Academy of Science Beijing100049China

A Laue microdiffraction beamline(BL03HB) was constructed at the Shanghai Synchrotron Radiation Facility(SSRF).This beamline features two consecutive focusing points in two different sectors within its end station, the first dedicated to protein crystallography and the other tailored to materials science applications. Based on a superbend dipole magnet with a magnetic field of 2.29 T, a two-stage focusing design was implemented with two sets of Kirkpatrick-Baez mirrors to achieve a micro white beam as small as 4.2 μ m ×4.3 μ m at the first sector and 0.9 μ m ×1.3 μ m at the second sector in the standard beamline operation mode at SSRF. The X-ray microbeam in the two sectors can be easily switched between monochromatic and white beams by moving a four-bounce monochromator in or out of the light path, respectively. In the protein crystallography sector, white-beam Laue microdiffraction was demonstrated to successfully determine the structure of protein crystals from only a few images of diffraction data collected by a Pilatus 2 M area detector. In the materials science sector,the white-beam Laue diffraction was collected in a reflection geometry using another Pilatus 2 M area detector, which could map the microstructural distribution on the sample surface by scanning the samples. In general, the BL03HB beamline promotes the application of Laue microdiffraction in both protein crystallography and materials science. This paper presents a comprehensive overview of the BL03HB beamline, end station, and the first commission results.

关键词： Crystallography White-beam Laue microdiffraction Beamline Synchrotron

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Macrocyclic peptides:up-and-coming weapons to combat antimicrobial resistance

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1786-1787页

作者： wen-Jing wang Xiang-Min Dong Guo-bo L Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduSichuanChina Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education Department of Medicinal ChemistryWest China School of PharmacySichuan UniversityChengduSichuanChina

Recently,two companion papers published in Nature reported a first-in-class tethered macrocyclic peptide antibiotic targeting carbapenem-resistant ***(CRAB)and unveiled their unique antibacterial mechanism,which invol... 详细信息

关键词： outer macrocyclic Macrocyclic

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Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway

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Asian Journal of Andrology 2024年第1期26卷 57-66页

作者： Chang-bo Zhao Wei-bo Chen wen-Zhen wang Fang-Xin Gong Cui-Qin Fan Ye Li Tian Lan wen-Jing wang Ming-Zhen Yuan Department of Urology Shandong Provincial HospitalShandong UniversityJinan 250012China Department of Andrology Liaocheng People's HospitalShandong UniversityLiaocheng 252000China Department of Urology The Second Hospital of Shandong UniversityJinan 250012China Department of Physiology School of Basic Medical SciencesShandong UniversityJinan 250012China

The major vascular complications associated with diabetes make the management of diabetic mellitus erectile dysfunction(DMED)a challenging *** factors contributing to DMED include oxidative stress,nitric oxide(NO)/cyclic guanosine monophosphate(cGMP)pathway activation,and apoptosis,while nitro-oleic acid(NO,-OA)has been shown to be beneficial in treating these aspects of this ***,herein,investigated the effects and possible mechanisms of NO,-OA on erectile function as assessed in a streptozotocin-induced rat model of *** results revealed that the erectile function of DMED rats was significantly impaired compared with that of the control ***,in response to 4 weeks of NO,-OA treatment,there was an improvement in erectile *** expression of oxidative stress-related indicators was significantly increased and the NO/cGMP pathway was impaired in the DMED *** expression of proapoptotic factors was increased,while that of antiapoptotic factors was decreased in the DMED ***,the cell morphology in the cavernous tissue of the DMED group also changed ***,-OA treatment significantly reversed all these changes observed in the DMED *** conclusion,NO,-OA treatment partially improved erectile function in DMED rats through mechanisms that included inhibition of oxidative stress,activation of the NO/cGMP pathway,and a reduction in apoptosis.

关键词： apoptosis diabetic mellitus erectile dysfunction nitro-oleic acid NO/cGMP pathway oxidative stress

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