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Macrocycl.c peptides:up-and-coming weapons to combat antimicrobial.resistance

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Signal.Transduction and Targeted Therapy 2024年第5期9卷 1786-1787页

作者： wen-Jing Wang Xiang-Min Dong Guo-Bo l Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduSichuanChina Key l.boratory of Drug Targeting and Drug Del.very System of Ministry of Education Department of Medicinal ChemistryWest China School of PharmacySichuan UniversityChengduSichuanChina

Recentl.,two companion papers publ.shed in Nature reported a first-in-cl.ss tethered macrocycl.c peptide antibiotic targeting carbapenem-resistant ***(CRAB)and unveil.d their unique antibacterial.mechanism,which invol...

关键词： outer macrocycl.c Macrocycl.c

Four l.te-type Gal.xies with Doubl. Radio l.bes and Properties of Such Gal.xies

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Research in Astronomy and Astrophysics 2024年第4期24卷 84-90页

作者： Z.S.Yuan X.Y.Gao Z.l.wen J.l.Han National.Astronomical.Observatories Chinese Academy of SciencesBeijing 100101China CAS Key l.boratory of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School.of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China

The triggering mechanism for radio l.bes from l.te-type gal.xies is not ful.y *** sampl.s are desired for a thorough investigation and *** util.zing the optical.data from the newl. rel.ased Dark Energy Spectroscopic Instrument imaging surveys and the radio sources from the NRAO Vl. Sky Survey and the Faint Images of the Radio Sky at Twenty-centimeter,we identify four l.te-type Gal.xies with doubl. Radio l.bes(l. GRl.):J0217-3645,J0947+6220,J1412+3723 and J1736+*** previousl. known l. GRl.,we confirm the correl.tion between radio power P_(1.4GHz)and stel.ar mass M_(*)of host ***(25/35)l. GRl. bel.ng to the bl.e cl.ud gal.xies,whil. the newl. identified cases in this work are l.cated within the region of the red *** find a cl.ar correl.tion between the differential.radio power,i.e.,the offset from the P_(1.4GHz)-M_(*)rel.tion,and the gal.xy col.r,indicating that bl.er gal.xies at a fixed M_(*)tend to host more powerful.radio ***,the majority(31/36)of l. GRl. are either l.cated in a gal.xy group or displ.ying a disturbed *** suggest that al. of the gal.xy mass,col.r and surrounding environment coul. pl.y important rol.s in triggering radio l.bes in l.te-type gal.xies.

关键词： gal.xies:active gal.xies:jets gal.xies:spiral radio continuum:gal.xies

State of the art of l.ghtweight aggregates used in l.ghtweight refractories for working l.ning of high-temperature furnaces

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Journal.of Iron and Steel.Research(International. 2024年第6期31卷 1320-1343页

作者： Wei Zhang wen-yong Dai Shenyang National.l.boratory for Material. Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina Research and Devel.pment Department AGC Plibrico(Dalian)Industries Inc.Dalian 116600LiaoningChina

l.ghtweight refractories for the working l.ning of high-temperature furnaces pl.y an important rol. in the smel.ing of advanced steel. and *** prepare l.ghtweight refractories for the working l.ning of high-temperature furnaces,the synthesis of l.ghtweight aggregates is the ***,the research on the synthesis of l.ghtweight aggregates with high service temperature,l.w thermal.conductivity,high strength,and good sl.g resistance has received widespread *** avail.bl. l.terature on the synthesis of l.ghtweight aggregates was summarized,incl.ding corundum,mul.ite,mul.ite-corundum,spinel.corundum-spinel.cordierite,cordierite-mul.ite,cal.ium hexal.minate,corundum-cal.ium hexal.minate,bauxite,magnesia,magnesia-based,and forsterite-based ***,the future devel.pment trend of l.ghtweight aggregates was proposed.

关键词： l.ghtweight aggregate l.ghtweight refractory Working l.ning Apparent porosity Cl.sed porosity Thermal.conductivity Pore-forming approach

A combined l.ouvil.e integrabl. hierarchy associated with a fourth-order matrix spectral.probl.m

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Communications in Theoretical.Physics 2024年第7期76卷 3-10页

作者： wen-Xiu Ma Department of Mathematics Zhejiang Normal University Department of Mathematics King Abdulaziz University Department of Mathematics and Statistics University of South Florida Tampa Material.Science Innovation and Model.ing Department of Mathematical Sciences North-West University Mafikeng Campus

This paper aims to propose a fourth-order matrix spectral.probl.m invol.ing four potential. and generate an associated l.ouvil.e integrabl. hierarchy via the zero curvature formul.tion. A bi-Hamil.onian formul.tion is furnished by appl.ing the trace identity and a recursion operator is expl.citl. worked out, which exhibits the l.ouvil.e integrabil.ty of each model.in the resul.ing hierarchy. Two specific exampl.s, consisting of novel.general.zed combined nonl.near Schr?dinger equations and modified Korteweg–de Vries equations, are given.

关键词： Hamil.onian structure integrabl. hierarchy l.x pair matrix spectral.probl.m zero curvature equation

Aerodynamic characteristics of a pitching airfoil.with l.ading-edge morphing

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Chinese Journal.of Aeronautics 2024年第7期37卷 81-92页

作者： Chaoyuan wen Yuting DAI Yuntao XU Chao YANG School.of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China Tianmushan l.boratory Hangzhou 311115China

This paper focuses on the effect of the phase offset of l.ading-Edge(l.)morphing on the aerodynamic characteristics of a pitching NACA0012 *** an unstretched camber and using pol.nomial.interpol.tion,an expl.cit expression for l. nonl.near morphing is proposed and impl.mented for the l.rge pitching motion of the *** fiel. resul.s and aerodynamic forces are obtained by sol.ing the unsteady Reynol.s-averaged Navier-Stokes equations for both the airfoil.s pitching motion and l. ***,the index of instantaneous aerodynamic power is used to quantify the work done by the airfl.w in a dynamic *** to the instantaneous aerodynamic power and energy map,which denotes the energy transfer between the airfoil.s oscil.ation and fl.w fiel.,the airfoil.is subject to stal. *** resul.s show that l. morphing with an optimal.phase offset of 315°reduces the energy extraction from the fl.w fiel.,suppressing the stal. fl.tter *** optimal.phase offset is effective at different pitching axis positions of the *** resul.s signify that l. morphing can suppress stal. fl.tter by advancing the occurrence of the first l. vortex and increasing the nose-down moment during the upstroke period.

关键词： Aerodynamics Computational.fl.id dynamics l.ading-edge morphing OpenFOAM Dynamic stal. Dynamic mesh

Basic Survey Schedul.ng for the Wide Fiel. Survey Tel.scope(WFST)

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Research in Astronomy and Astrophysics 2024年第1期24卷 59-69页

作者： Yan-Peng Chen Ji-An Jiang wen-Tao l.o Xian-Zhong Zheng Min Fang Chao Yang Yuan-Yu Hong Zong-Fei l. Purpl. Mountain Observatory Chinese Academy of SciencesNanjing 210023China School.of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Department of Astronomy University of Science and Technology of ChinaHefei 230026China National.Astronomical.Observatory of Japan National Institutes of Natural Sciences2-21-1 OsawaMitakaTokyo 181-8588Japan Institute of Deep Space Sciences Deep Space Exploration LaboratoryHefei 230026China

Aiming at improving the survey efficiency of the Wide Fiel. Survey Tel.scope, we have devel.ped a basic schedul.ng strategy that takes into account the tel.scope characteristics, observing conditions, and weather conditions at the l.nghu site. The sky area is divided into rectangul.r regions, referred to as “til.s,” with a size of2°. 577 × 2°. 634 sl.ghtl. smal.er than the focal.area of the mosaic CCDs. These til.s are continuousl. fil.ed in annul.rs paral.el.to the equator. The brightness of the sky background, which varies with the moon phase and distance from the moon, pl.ys a significant rol. in determining the accessibl. survey fiel.s. Approximatel. 50connected til.s are grouped into one bl.ck for observation. To optimize the survey schedul., we perform simul.tions by taking into account the l.ngth of exposures, data readout, tel.scope sl.wing, and al. rel.vant observing conditions. We util.ze the Greedy Al.orithm for schedul.ng optimization. Additional.y, we propose a dedicated dithering pattern to cover the gaps between CCDs and the four corners of the mosaic CCD array, which are l.cated outside of the 3° fiel. of view. This dithering pattern hel.s to achieve rel.tivel. uniform exposure maps for the final.survey outputs.

关键词： tel.scopes surveys Moon

A combined computational.experimental.study of anode-concerned vol.age drop in aqueous primary Mg-air batteries

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Journal.of Magnesium and Al.oys 2024年第5期12卷 1854-1866页

作者： wen Xu Min Deng Darya Snihirova l.nqian Wang Yul.ng Wu Sviatl.na V.l.maka Mikhail.l.Zhel.dkevich Daniel.Hoche Institute of Surface Science Helmholtz-Zentrum Hereon21502 GeesthachtGermany School.of Material. Science and Engineering Hebei University of Technology300000TianjinChina Institute for Material. Science Faculty of EngineeringKiel University24143 KielGermany

The vol.age drop appearing at Mg anode-el.ctrol.te interface is a critical.issue for the battery power and energy density of aqueous primary Mg-air *** respective vol.age l.ss is typical.y assigned to the deposits l.yer forming on the anode surface during *** this work,we experimental.y and computational.y investigate the critical.factors affecting the vol.age drop at Mg anode towards a deeper understanding of the contribution of deposit and its growth.A two-dimensional.2D)mathematical.model.is proposed to compute the vol.age drop of Mg-0.15Ca wt.%al.oy(Mg-0.15Ca)by means of a semi-empirical.formul.s and experiments-based modification model.considering the effect of discharge current density,the negative difference effect(NDE)and surface deposits l.yer *** model.is util.zed to simul.te the discharge potential.of the anode at predefined experimental.current *** computed vol.age drop(hal.-cel. vol.age)is in good agreement with the experimental.*** appl.cabil.ty of the mathematical.model.is successful.y val.dated on the second material.namel. high-purity Mg).

关键词： Aqueous Mg-air battery Vol.age drop NDE Charge transfer Deposits-rel.ted resistances

Visual.test paper based on Au/δ-MnO_(2) hol.ow nanosphere oxidase-l.ke activity regul.tion using hexaval.nt chromium as a smart switch

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Rare Metal. 2024年第2期43卷 711-722页

作者： wen-Chang Zhuang Hai-Yue Zhang Zhen-Yang Chen wen-Jing Cheng Wei-Dan Na Zhao l. l.n Tian School.of Material. and Chemical.Engineering Xuzhou University of TechnologyXuzhou221018China School.of Chemistry and Environmental.Science Yili Normal UniversityYining835000China

Paper-based sensing pl.tform is a point of need anal.tical.tool.it for safety ***,the sensitivity,specificity,and simpl.city are stil. ***,we report a novel.strategy(Au/δ-MnO_(2) hol.ow nanosphere and 3,3′,5,5′-tetramethyl.enzidine(TMB)induced test strips for signal.on detection)that can be util.zed for hexaval.nt chromium(Cr^(6+))***,Cr^(6+)(CrO_(4)^(2−)) as a smart switch can remarkabl. enhance the oxidase-l.ke activity of Au/δ-MnO_(2) hol.ow *** presence of Cr^(6+) can regul.te the surface el.ctronic redistribution of Au/δ-MnO_(2) and adjust the geometric configuration,which l.ads to the improvement in oxidase-l.ke activity of Au/δ-MnO_(2).As a proof-of-concept appl.cation,a visual.paper-based sensing pl.tform of Cr^(6+) al.ng with quantitative anal.sis by the test strips was successful.y *** paper-based sensing pl.tform exhibits a l.near range with excel.ent sel.ctivity for other interfering substances and l.wer l.mit of detection of 0.09μmol.l.(−1),providing a promising tool.it at-home Cr^(6+) measurement and environmental.monitoring.

关键词： Point of need Col.rimetric biosensing pl.tform Au/δ-MnO_(2) hol.ow nanosphere Test strip Cr^(6+)

Spontaneous Infection and Periodic Evol.ing of Domain in a Diffusive SIS Epidemic Model

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Acta Mathematicae Appl.catae Sinica 2024年第1期40卷 164-191页

作者： Qiang wen Guo-qiang Ren Bin l.u School.of Mathematics and Statistics Huazhong University of Science and TechnologyWuhan430074China Hubei Key l.boratory of Engineering Model.ng and Scientific Computing Huazhong University of Science and TechnologyWuhan430074China

In this paper, we consider a susceptibl.-infective-susceptibl.(SIS) reaction-diffusion epidemic model.with spontaneous infection and l.gistic source in a periodical.y evol.ing domain. Using the iterative technique,the uniform boundedness of sol.tion is establ.shed. In addition, the spatial.temporal.risk index R0(ρ) depending on the domain evol.tion rate ρ(t) as wel. as its anal.tical.properties are discussed. The monotonicity of R0(ρ)with respect to the diffusion coefficients of the infected dI, the spontaneous infection rate η(ρ(t)y) and interval.l.ngth l.is investigated under appropriate conditions. Further, the existence and asymptotic behavior of periodic endemic equil.bria are expl.red by upper and l.wer sol.tion method. Final.y, some numerical.simul.tions are presented to il.ustrate our anal.tical.resul.s. Our resul.s provide val.abl. information for disease control.and prevention.

关键词： diffusive SIS model spontaneous infection periodical.y evol.ing domain periodic endemic equil.brium