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Primary dolostone related to the Cretaceous lacustrine hydrothermal sedimentation in Qingxi sag, Jiuquan Basin on the northern Tibetan Plateau

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Science China Earth Sciences 2013年第4期56卷 2080-2093页

作者： wen HuaGuo ZHENG RongCai QING HaiRuo fan MingTao LI YanAn GONG BoShi State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of Technology Institute of Sedimentary Geology Chengdu University of Technology Department of Geology University of Regina Yumen Oilfield Company of PetroChina

Based on comprehensive studies in petrography, petrofabric analysis and geochemistry, this paper describes a unique and rare laminated micritic ferruginous primary dolostone crystallized and precipitated from the alkaline hot brine under the conditions of the Mesozoic faulted lake basin. The main rock-forming mineral of this dolostone is ferruginous dolomite with a micritic structure. This dolomite mostly exhibits laminae of 0.1-1 mm thick and is often discovered with other minerals, such as albite, analcite, barite and dickite, which have at least two types of interbedded laminae. Petrogeochemistry reveals that this dolostone contains a large number of typomorphic elements of hydrothermal sedimentation, including Sb, Ba, Sr, Mn, and V. In addition, the LREE is in relatively high concentrations and possesses the typical REE distribution pattern with negative Eu anomaly. Oxygen isotope values （C^ISOpDB） range from 5.89%~ to 14.15%o with an average of 9.69%0. The ratio of 87Sr/86Sr is between 0.711648 and 0.719546, with an average of 0.714718. These data indicate that the depositional environment is a stable, blocked, anoxic low-lying hot brine pool in the bottom of deep lake controlled by basement faults. The hydrothermal fluid is the alkaline hot brine formed by the combination of the infiltration lake water and mantle-derived magmatic water, consisting of many ions, including Ca2＋, Mg2＋ and Fe2＋. Under the driving flow power of magmatic heat, gravity and compaction, the hy- drothermal fluid overcame the overburden pressure and hydrostatic pressure of the lake water body, and boiled to explosion, and then the explosion shattered the original laminated micritic ferruginous primary dolostone near the vent and then formed a new type of dolostone called shattered ＂hydroexplosion breccias＂. In the low-lying, unperturbed hot brine pool, far from the vent, the laminated micritic ferruginous primary dolostone was quickly crystallized and chemicals precipitated from the hy-

关键词： primary ferruginous dolostone hydrothermal sedimentation fault lakes Cretaceous Jiuquan Basin

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Maize ABP2 enhances tolerance to drought and salt stress in transgenic Arabidopsis

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Journal of Integrative Agriculture 2018年第11期17卷 2379-2393页

作者： ZONG Na LI Xing-juan WANG Lei WANG Ying wen Hong-tao LI Ling ZHANG Xia fan Yun-liu ZHAO Jun National Key Facility for Crop Gene Resources and Genetic Improvement/Faculty of Maize Functional Genomics Biotechnology Research Institute Chinese Academy of Agricultural Sciences Guangdong Key Laboratory of Biotechnology for Plant Development/College of Life Science South China Normal University

Abiotic stresses, especially drought and salt, severely affect maize production, which is one of the most important cereal crops in the world. Breeding stress-tolerant maize through biotechnology is urgently needed to maintain maize production. Therefore, it is important to identify new genes that can enhance both drought and salt stress tolerance for molecular breeding. In this study, we identified a maize ABA （abscisic acid）-responsive element （ABRE） binding protein from a 17-day post-pollination （dpp） maize embryo cDNA library by yeast one-hybrid screen using the ABRE2 sequence of the maize Cat1 gene as bait. This protein, designated, ABRE binding protein 2 （ABP2）, belongs to the bZIP transcription factor family. Endogenous expression of ABP2 in maize can be detected in different tissues at various development stages, and can be induced by drought, salt, reactive oxygen species （ROS）-generating agents, and ABA treatment. Constitutive expression of ABP2 in transgenic Arabidopsis plants enhanced tolerance to drought and salt stress, and increased sensitivity to ABA. In exploring the mechanism by which ABP2 can stimulate abiotic stress tolerance, we found that ROS levels were reduced and expression of stress-responsive and carbon metabolism-related genes was enhanced by constitutive ABP2 expression in transgenic plants. In Short, we identified a maize bZIP transcription factor which can enhance both drought and salt tolerance of plants.

关键词： ABP2 maize transcription factor drought salt transgenic Arabidopsis

Study of the retina algorithm on FPGA for fast tracking

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Nuclear Science and Techniques 2019年第8期30卷 84-91页

作者： Zi-Xuan Song wen-Di Deng Gilles De Lentdecker Guang-Ming Huang Hua Pei Yi-fan Yang Dong Wang Frederic Robert Central China Normal University Wuhan 430079China Universite libre de Bruxelles Av.F.Roosevelt 501050 BrusselsBelgium

Real-time track reconstruction in high-energy physics experiments at colliders running at high luminosity is very challenging for trigger systems. To perform pattern recognition and track fitting, artificial retina or Hough transformation algorithms have been introduced to the field typically implemented on state-of-the-art field programmable gate array(FPGA) devices. In this paper, we report on two FPGA implementations of the retina algorithm: one using a mixed Floating-Point core and the other using Fixed-Point and Look-Up Table, and detailed measurements of the retina performance are investigated and compared. So far, the retina has mainly been used in a detector configuration comprising parallel planes, and the goal of our work is to study the hardware implementation of the retina algorithm and estimate the possibility of using such a method in a real experiment.

关键词： Fast tracking Field programmable gate array Trigger

信息溯源和智能感知技术在出境货物木质包装监管中的应用研究

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中国口岸科学技术 2024年第9期6卷 64-69页

作者：刘钊张晓伟范文熊永红蔡晓露刘晓峰邱国强张双想武汉海关武汉430040

本文详细描述了武汉海关基于信息溯源和智能感知信息化技术,开展出境货物木质包装检疫监管新模式相关探索的应用研究。通过建立标准统一的公共信息化服务平台,打破企业与监管部门之间的数据藩篱;通过将高精度传感设备嵌入企业生产环节,... 详细信息

本文详细描述了武汉海关基于信息溯源和智能感知信息化技术,开展出境货物木质包装检疫监管新模式相关探索的应用研究。通过建立标准统一的公共信息化服务平台,打破企业与监管部门之间的数据藩篱;通过将高精度传感设备嵌入企业生产环节,实时感知除害作业中的温度、湿度、持续时间等技术指征变化,由算法模型智能判别除害作业的合规性,形成了监管环节的适时前移;应用二维码溯源技术整合企业、货物、除害作业和IPPC标识等多种要素信息,建立木质包装“档案信息”,将监管顺势后延。经过不断的实践改进,逐步建立起全流程、可追溯、智能化的出境货物木质包装检疫监管新模式,有效解决出境货物木质包装易伪造、难追溯的监管难题。

关键词：智慧海关动植物检疫木质包装人工智能信息溯源

In situ-prepared homogeneous supramolecular organic framework drug delivery systems(sof-DDSs)：Overcoming cancer multidrug resistance and controlled release

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Chinese Chemical Letters 2017年第4期28卷 798-806页

作者： Jia Tian Chi Yao wen-Lin Yang Lei Zhang Dan-Wei Zhang Hui Wang fan Zhang Yi Liu Zhan-Ting Li Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Department of Chemistry Fudan University Shanghai 200433 China Department of Pathology School of Basic Medical Sciences Fudan University Shanghai 200032 China The Molecular Foundry Lawrence Berkeley National Laboratory Berkeley 94720 United States

Water-soluble three-dimensional porous supramolecular organic frameworks（SOFs） have been demonstrated as a new generation of homogeneous polycationic platforms for anti-cancer drug *** new SOF drug delivery systems（sof-DDSs） can adsorb dianionic pemetrexed（PMX）,a clinically used chemotherapeutic agent instantaneously upon dissolving in water,which is driven by both electrostatic attraction and *** in situ-prepared PMX@SOFs are highly stable and can avoid important release of the drug during plasm circulation and overcome the multidrug resistance of human breast MCF-7/Adr cancer cells to enter the cancer *** microenvironment of cancer cells promotes the release of the drug in cancer *** in vitro and in vivo studies have revealed that sofDDSs considerably improve the treatment efficacy of PMX,leading to 6-12-fold reduction of the IC50 values,as compared with that of PMX *** new drug delivery strategy omits the loading process required by most of reported nanoparticle-based delivery systems and thus holds promise for future development of low-cost drug delivery systems

关键词： Supramolecular organic framework In situ preparation Drug delivery Controlled release Pemetrexed Human breast cancer Multidrug resistance

基于Web of Science和CNKI的羊肚菌研究文献计量分析

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中国食用菌 2022年第7期41卷 1-12页

作者：王彦蕊潘立超任玉龑郭晓鹏任海伟范文广李志忠兰州理工大学生命科学与工程学院甘肃兰州730050 西北低碳城镇支撑技术省部共建协同创新中心甘肃兰州730050

羊肚菌是一类名贵的食药兼用菌,被誉为“菌中之王”。为深入了解国内外有关羊肚菌的研究现状与发展态势,以Web of Science(WoS)核心合集和中国知网(CNKI)数据库为基础,采用文献计量学方法对羊肚菌主题相关文献的发文作者、期刊、机构以... 详细信息

羊肚菌是一类名贵的食药兼用菌,被誉为“菌中之王”。为深入了解国内外有关羊肚菌的研究现状与发展态势,以Web of Science(WoS)核心合集和中国知网(CNKI)数据库为基础,采用文献计量学方法对羊肚菌主题相关文献的发文作者、期刊、机构以及关键词等内容进行分析。结果表明,自2012年实现羊肚菌的大田商业栽培后,研究热度日益活跃,近五年发文量总体呈现上升趋势。美国(263篇)、法国(147篇)和中国(141篇)发文量位居前三,发文量占比均超过20%,各国之间合作密切;法国国家科学研究中心的发文量(55篇)和总被引频次(2261次)位居第一;接收文献最多的期刊为《Mycologia》;有关羊肚菌的研究主要集中在人工栽培、液体发酵、多糖提取、抗氧化等方面。综上,羊肚菌领域仍处于活跃的发展状态,应用场景日趋丰富,未来可能会在羊肚菌栽培技术和功能性食品、药品研发上挖掘到崭新的研究应用方向。

关键词：羊肚菌人工栽培营养成分文献计量知识图谱

Rapid detection of Shigella and Salmonella in rhesus monkeys by loop-mediated isothermal amplification assay

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中国实验动物学报 2016年第1期24卷 7-13页

作者：叶莉吴芳 WANG Yi-jia ZHENG Jun-wen fan Jun-wen DING Ming SHI Yan-sheng 张小飞白杰英 Laboratory Animal Center Academy of Military Medical Sciences Beijing 100071 China the Sixth Clinical School Capital Medical University Beijing 100029 Capital Normal University Beijing 100048 Beijing Institute of Veterinary Drug Control Beijing 102600

Objective To establish a loop-mediated isothermal amplification( LAMP) method for detecting diarrhea pathogens( Shigella and Salmonella) in rhesus monkeys and evaluate the application of the LAMP method for detecting bacterial diseases in nonhuman primate laboratory animals. Materials and Methods A total of 205 fecal samples of rhesus monkeys were detected in this LAMP assay. The specificity and sensitivity of LAMP for Shigella and Salmonella were analyzed,and real-time polymerase chain reaction( REAL-TIME PCR) assay was employed as control. Results The LAMP method established here needed only 45 min to complete the reaction at 63℃. Its detection limit was 10 pg / μL and with a high specificity. The positive rate of Shigella and Salmonella was 1. 5% and 6. 3%,respectively. Conclusions Here we have established a fast and simple Shigella and Salmonella LAMP detection method that has strong specificity and high sensitivity and is suitable for rapid detection of bacterial disease in macaques. The development of this rapid detection kit is underway,and it will be helpful to the diarrhea detection.

关键词：经典条件反射操作式条件反射 SD大鼠 Wistar大鼠学习记忆

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Nanoclusters Au19Pd and Au19Pt Catalyzing CO Oxidation: a Density Functional Study

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Chinese Journal of Structural Chemistry 2018年第12期37卷 1849-1859,1843页

作者： ZHANG Jing YU Wei-Ling ZHOU Sheng-Hua LI Yi ZHANG Yong-fan CHEN wen-Kai Department of Chemistry Fuzhou UniversityFuzhou 350116China State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou 350116China Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry Xiamen UniversityXiamen 610005China

The gold atoms on the Au20 cluster had been substituted by the palladium and platinum atoms to obtain the doped clusters with more stable geometries as a function of the bind energy and interaction energy in the previous study. Therefore, we investigated the catalytic activities of the Au_(19)Pd and Au_(19)Pt clusters for CO oxidation along the Langmuir-Hinshelwood mechanism. It is found that the coadsorption of CO and O2 on the doped clusters is obviously stronger than on the Au20 cluster, especially on the doped atom, which makes potential energy of the transition state lower than the total energy of the reactants so that it can promote CO oxidation. The reaction on these doped clusters with the heteroatom on the vertex is more difficult. However, the Au_(19)Pd(S) is more prone to catalyzing the CO oxidation, in which the rate-limiting step has the lower energy barrier of 38.84 kJ/mol for this study. Therefore, the single atom can be modified to change the catalytic activity of the cluster for the CO oxidation. Meanwhile, the different sites on the clusters have different strengths of activity for the reaction.

关键词： bimetallic cluster catalytic activity CO oxidation density functional theory

基于microRNA-mRNA配对表达谱进行联合分析的方法学进展

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生物技术通讯 2017年第4期28卷 545-550页

作者：赵路阳张康顾成磊叶明侠范文生韩为东孟元光解放军总医院妇产科北京100853 北京华信医院妇产科北京100016 解放军第309医院妇产科北京100091 解放军总医院基础研究所北京100853

microRNA(miRNA)是一类内源性非编码小RNA,主要通过降解靶基因或抑制靶基因的翻译而调控表达。由于其作用机制复杂,目前尚未发现高效而低成本的靶标定位方法。近年来,基于碱基互补配对原理的计算机预测法被广为应用,但此方法假阳性高,... 详细信息

microRNA(miRNA)是一类内源性非编码小RNA,主要通过降解靶基因或抑制靶基因的翻译而调控表达。由于其作用机制复杂,目前尚未发现高效而低成本的靶标定位方法。近年来,基于碱基互补配对原理的计算机预测法被广为应用,但此方法假阳性高,不同算法所得结果差异大,会误导和干扰下游的功能学实验。因此,有研究者提出结合样本配对mRNA表达量来进一步定位靶基因,明确miRNA-mRNA相互作用方式,这种联合分析的方法受到了普遍认可。本文回顾了近年来基于miRNA-mRNA配对表达谱进行联合分析的方法学进展,并简要分析各类方法的应用范围和优缺点,为后续研究者选择方法提供参考。

关键词： microRNA microRNA靶标预测 microRNA—mRNA相互作用联合分析