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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li Hua Zhang Lian-Lian Wang wen-wen Liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

Burden of mental disorders and risk factors in the Western Pacific region from 1990 to 2021

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World Journal of Psychiatry 2025年第1期15卷 93-105页

作者： Ya-Xin Xu Xiao-Xuan niu wen-Chang Jia Jing wen Xue-Lin Cheng Yan Han Ming-Hui Peng Jing Zhou Yao Liu Sun-Fang Jiang Xiao-Pan Li Department of Health Management Centre Zhongshan HospitalFudan UniversityShanghai 200030China Department of General Practice Zhongshan HospitalFudan UniversityShanghai 200030China Department of Nutrition Zhongshan HospitalFudan UniversityShanghai 200032China School of Public Health Fudan UniversityShanghai 200032China

BACKGROUND The burden of mental disorders(MD)in the Western Pacific Region(WPR)re-mains a critical public health concern,with substantial variations across demogra-phics and *** To analyze the burden of MD in the WPR from 1990 to 2021,along with associated risk factors,to reveal changing trends and emerging *** We used data from the Global Burden of Disease 2021,analyzing prevalence,incidence,and disability-adjusted life years(DALYs)of MD from 1990 to *** methods included age-standardisation and uncertainty analysis to address variations in population structure and data *** Between 1990 and 2021,the prevalence of MD rose from 174.40 million cases[95%uncertainty interval(UI):160.17-189.84]to 234.90 million cases(95%UI:219.04-252.50),with corresponding DALYs increasing from 22.8 million(95%UI:17.22-28.79)to 32.07 million(95%UI:24.50-40.68).During this period,the burden of MD shifted towards older age *** and anxiety disorders were predominant,with females showing higher DALYs for depressive and anxiety disorders,and males more affected by conduct disorders,attention-deficit hyperactivity disorder,and autism spectrum ***,New Zealand,and Malaysia reported the highest burdens,whereas Vietnam,China,and Brunei Darussalam reported the ***,childhood sexual abuse and bullying,and intimate partner violence emerged as significant risk *** This study highlights the significant burden of MD in the WPR,with variations by age,gender,and *** coronavirus disease 2019 pandemic has exacerbated the situation,emphasizing the need for a coordinated response.

关键词： Mental disorders Western pacific region Global Burden of Disease Risk factors Disability-adjusted life years

CT增强检查中临床护理路径的应用与意义初步研究

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中国医学创新 2017年第6期14卷 68-70页

作者：赖文娟牛艳迪高观鸿罗玲广东省深圳市龙岗中心医院广东深圳518100

目的:分析讨论临床护理路径应用在CT增强检查中的临床效果。方法:选择2015年6月-2016年6月本院收治的102例接受CT增强检查患者作为研究对象,根据随机数字表法将患者分为对照组和试验组,对照组采用常规护理方法,试验组采用临床护理路径方... 详细信息

目的:分析讨论临床护理路径应用在CT增强检查中的临床效果。方法:选择2015年6月-2016年6月本院收治的102例接受CT增强检查患者作为研究对象,根据随机数字表法将患者分为对照组和试验组,对照组采用常规护理方法,试验组采用临床护理路径方法,比较两组的临床效果。结果:试验组患者的临床护理总满意率为96.08%,明显高于对照组的78.43%,差异有统计学意义(P<0.05);试验组患者的不良反应发生率为7.84%,明显低于对照组的25.49%,差异有统计学意义(P<0.05)。结论:临床护理路径应用在CT增强检查中疗效显著,提高临床护理满意度,降低并发症发生率,在临床中值得广泛的推广应用。

关键词： CT增强检查临床护理路径临床疗效

Global Helically Symmetric Solutions to 3D MHD Equations

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Acta Mathematicae Applicatae Sinica 2014年第2期30卷 347-358页

作者： wen GAO Zhen-hua GUO Dong-juan niu Northwest University School of Mathematical Sciences Capital Normal University

We prove the existence and uniqueness of global strong solutions to the Cauchy problem of the three-dimensional magnetohydrodynamic equations in R3 when initial data are helically symmetric. Moreover, the large-time b... 详细信息

关键词： magnetohydrodynamic equations helically symmetric solutions large-time behavior of solutions

Anomalous pattern of ocean heat content during different phases of the solar cycle in the tropical Pacific

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Atmospheric and Oceanic Science Letters 2017年第1期10卷 9-16页

作者： HUO wen-juan XIAO Zi-niu State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China College of Earth Science University of Chinese Academy of Sciences Beijing China

Solar radiation is a forcing of the climate system with a quasi-11-year *** a quasi-period forcing,the influence of the phase of the solar cycle on the ocean system is an interesting topic of *** this paper,the authors investigate a particular feature,the ocean heat content（OHC）anomaly,in different phases of the total solar irradiance（TSI） *** results show that almost opposite spatial patterns appear in the tropical Pacific during the ascending and declining phases of the TSI *** analysis reveals the presence of the quasi-decadal（11-year） solar signal in the SST,OHC and surface zonal wind anomaly field over the tropical Pacific with a high level of statistical confidence（95%）.It is noted that the maximum centers of the ocean temperature anomaly are trapped in the upper ocean above the main pycnocline,in which the variations of OHC are related closely with zonal wind and ocean currents.

关键词： Ocean heat content anomaly total solar irradiance solar cycle tropical Pacific

Development and Validation of a Recombinant Envelop Glycoprotein Based Indirect Enzyme-Linked Immunosorbent Assay to Detect the Antibody to REV

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Agricultural Sciences in China 2010年第3期9卷 432-439页

作者： ZHANG wen-juan PEI Zong-fei SHI Feng niu Xing niu Zhong-xiang College of Veterinary Medicine Shandong Agricultural University Tai＇an 271018 P.R.China Veterinary Department Shandong Vocational Animal Science and Veterinary College Weifang 261000 P.R.China

Based on the antigenic analysis of Reticuloendotheliosis virus （REV） envelop glycoprotein （env） protein, an alternative indirect enzyme-linked immunosorbent assay （ELISA） for detection of REV antibody was developed using a truncated env protein of REV produced in Escherichia coli. This assay was validated by comparison with an indirect immunofluorescence assay （IFA） and a REV-based ELISA. The diagnostic sensitivity （DSN）, specificity （DSP） and accuracy of the env indirect-ELISA （ienv-ELISA） were 93.7, 93.3 and 93.6% compared with IFA on 1 380 field serum samples, and 84.8, 95.2 and 91.7% compared with the REV-based ELISA on 96 field sera, respectively. Cross-reactivity assay showed that this assay was REV-specific. Repeatability test revealed that the coefficients of variation of positive sera within and between runs were less than 15%. This method is simpler to produce and perform, time-saving and suitable for large scale survey of REV antibody at low cost.

关键词： REV env protein prokaryotic expression indirect ELISA antibody detection

The impact of solar activity on the 2015/16 El Ni?o event

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Atmospheric and Oceanic Science Letters 2016年第6期9卷 428-435页

作者： HUO wen-juan XIAO Zi-niu State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Earth Science University of Chinese Academy of SciencesBeijingChina

Recent SST and atmospheric circulation anomaly data suggest that the 2015/16 El Nino event is quickly decaying. Some researchers have predicted a forthcoming La Nina event in late summer or early fall 2016. From the perspective of the modulation of tropical SST by solar activity, the authors studied the evolution of the 2015/16 El Nino event, which occurred right after the 2014 solar peak year. Based on statistical and composite analysis, a significant positive correlation was found between sunspot number index and El Ni^o Modoki index, with a lag of two years. A clear evolution of El Nino Modoki events was found within 1-3 years following each solar peak year during the past 126 years, suggesting that anomalously strong solar activity during solar peak periods favors the triggering of an El Nino Modoki event. The patterns of seasonal mean SST and wind anomalies since 2014 are more like a mixture of two types of El Nino （i.e. eastern Pacific El Nino and El Nino Modoki）, which is similar to the pattern modulated by solar activity during the years following a solar peak. Therefore, the El Nino Modoki component in the 2015/16 El Nino event may be a consequence of solar activity, which probably will not decay as quickly as the eastern Pacific El Nino component. The positive SST anomaly will probably sustain in the central equatorial Pacific （around the dateline） and the northeastern Pacific along the coast of North America, with a low-intensity level, during the second half of 2016.

关键词： El Nino El Nino Modoki solaractivity SST atmospheric circulation

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World Journal of Clinical Cases 2025年第6期13卷 24-29页

作者： wen-Jin Yuan Yi-juan Zheng Bing-Rong Zhang Yi-Jie Lin You Li Yan-Yan Qiu Xue-Ping Yu Department of Infection Disease Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian provinceFujian Medical University Affiliated First Quanzhou HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/*** SUMMARY This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary *** revealed an ileocecal *** discontinuing hydroxyurea therapy for 6 months,follow-up colonoscopy showed a significant reduction in the *** We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

关键词： Hydroxyurea Ulcer Abdominal pain Thrombocythemia Colonoscopy Case report

改进的坐标残差网络应用于17-4PH材料蚀后剩余寿命预测研究

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西安交通大学学报 2025年第1期59卷 206-214页

作者：邸娟王程波贺磊牛亚龙彭超义王建锋太原科技大学车辆与交通工程学院太原030024 株洲时代新材料科技股份有限公司湖南株洲412007 湖南大学材料科学与工程学院长沙410082 同济大学工程结构性能演化与控制教育部重点实验室上海200092

为解决材料汽蚀损伤后剩余使用寿命预测困难的科学问题,提出了一种融合卷积神经网络技术的寿命预测方法,具体采用残差网络(ResNet)模型,并嵌入坐标注意力机制(CA),通过对模型进行卷积、通道数及下采样方式的优化,构建改进的坐标残差网络... 详细信息

为解决材料汽蚀损伤后剩余使用寿命预测困难的科学问题,提出了一种融合卷积神经网络技术的寿命预测方法,具体采用残差网络(ResNet)模型,并嵌入坐标注意力机制(CA),通过对模型进行卷积、通道数及下采样方式的优化,构建改进的坐标残差网络(CA-ResNet)模型,以实现对17-4PH材料汽蚀损伤后剩余使用寿命的精确预测。基于超声波汽蚀试验得到的汽蚀特性曲线,通过逻辑回归(Logistic)方程对汽蚀阶段进行定量划分,并定义寿命系数ζ,同时借助超景深显微镜获取材料损伤后不同时刻的显微图像数据库,并与寿命系数ζ相对应。研究结果表明,改进的CA-ResNet网络模型在CIFAR10公开数据集上验证准确率可达92.2%,在收集的17-4PH材料的汽蚀损伤数据集上的验证准确率可达93.2%,相比ResNet18网络模型,准确率分别提高了1.5%和3.5%。通过学习率、批处理量等超参数优化后,该模型在汽蚀损伤数据集上准确率可达95.0%。采用端到端的数据驱动思想,可实现从汽蚀损伤形貌到汽蚀寿命的精确预测。

关键词：残差网络坐标注意力机制汽蚀寿命预测