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Dispatchable Capability of Aggregated Electric Vehicle Charging in Distribution Systems

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Energy Engineering 2025年第1期122卷 129-152页

作者： ShiqianWang Bo Liu Yuanpeng Hua Qiuyan Li Binhua tang Jianshu Zhou Yue Xiang Economic and Technology Research Institute State Grid Henan Electric Power CompanyZhengzhou450052China College of Electrical Engineering Sichuan UniversityChengdu610065China

This paper introduces a method for modeling the entire aggregated electric vehicle(EV)charging process and analyzing its dispatchable *** methodology involves developing a model for aggregated EV charging at the charging station level,estimating its physical dispatchable capability,determining its economic dispatchable capability under economic incentives,modeling its participation in the grid,and investigating the effects of different scenarios and EV penetration on the aggregated load dispatch and dispatchable *** results indicate that using economic dispatchable capability reduces charging prices by 9.7%compared to physical dispatchable capability and 9.3%compared to disorderly ***,the peak-to-valley difference is reduced by 64.6%when applying economic dispatchable capability with 20%EV penetration and residential base load,compared to disorderly charging.

关键词： Aggregated charging dispatchable capability peak shaving and valley filling the economics of charging demand response

Multicomponent polymerization of elemental sulfur,difluoromethylene phosphobetaine and aryl silyl ethers toward aromatic poly(O,O′-monothiocarbonate)s

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Science China Chemistry 2025年

作者： Yongjiang Yu Rongrong Hu Ben Zhong tang State Key Laboratory of Luminescent Materials and Devices Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates South China University of Technology School of Science and Engineering Shenzhen Institute of Aggregate Science and Technology The Chinese University of Hong Kong AIE Institute

Polythiocarbonates with similar structures to polycarbonates, have emerged as a group of promising sulfur-containing polymers with a range of practical applications, taking advantages of their excellent optical properties, good thermal stability and filmforming ability, and so on. However, the synthesis of polythiocarbonates generally suffered from mixed isomeric structures of repeating units, and hazardous sulfur-containing reagents. In this work, an efficient multicomponent reaction of elemental sulfur,difluoromethylene phosphobetaine（PDFA）, and aryl silyl ethers was designed with the assistance of organic base 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene（MTBD） to produce 12 kinds of O,O′-monothiocarbonate compounds in up to 93% yields,taking advantages of the unique chemical property of difluorocarbene, and the deprotection of silyl group by F-generated from PDFA. Most importantly, the MTBD-assisted multicomponent polymerization of bis（aryl silyl ether）s, elemental sulfur, and PDFA was developed, affording 12 kinds of poly（O,O′-monothiocarbonate）s with well-defined structures, high Mws of up to16900 g/mol and high yields（up to 99%）. These poly（O,O′-monothiocarbonate）s possessed good film-forming properties and thermal stability, high light refractive indices and transmittance. The facile synthesis of these polymonothiocarbonates might pave the way for the development of promising sulfur-containing polymer materials.

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Computer-Assisted Path Planning for Minimally Invasive Vascular Surgery

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Chinese Journal of Electronics 2018年第6期27卷 1241-1249页

作者： HUANG Dongjin tang Pengbin WANG yin LI Hejuan tang wen DING Youdong Shanghai Film Academy Shanghai University Dpartement d'informatique et de recherche oprationnelle Universitde Montral Department of Creative Technology University of Bournemouth

Path planning assisted by two-dimensional medical images is an essential part of minimally invasive diagnosis and treatment for cardiovascular diseases. Due to the complex background of angiography images and intricate vascular structure with multi-branch and stenoses,creating accurate pathways from angiography image is a challenge task. We present a new path planning methodology based on angiography medical images using the steady fluid dynamics. Our novel approach is useful in many medical applications, such as for computer-assisted medical images analysis and the follow-on image-guided interventions. A graph-cuts based energy function was applied to the vessel segmentation of angiography images in order to obtain boundary information. We have adopted Finite volume method(FVM) to simulate the Newtonian fluid inside the segmented blood vessels, and a set of isobars under the steady fluid condition are obtained by Meandering Triangles algorithm. The selected center points of isobars are organized to generate the directed vessels-tree, from which the vascular stenoses are automatically detected and the final surgical path is generated with branches. Our method can be used for quantitative path analysis, and we show experimental results to demonstrate that the versatility and applicability of the algorithm in obtaining single-pixel surgical path with good performance, high accuracy and less manual interventions, especially it is robust on complex vascular structures.

关键词： Minimally invasive surgery Path planning Fluid dynamics Medical images analysis

基于ANSYS的平面电容传感器阵列三维仿真研究

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传感器与微系统 2016年第4期35卷 45-48页

作者：刘泽良温银堂梁希李慧剑燕山大学建筑工程与力学学院河北秦皇岛066004 燕山大学电气工程学院河北秦皇岛066004

通过电磁场有限元分析软件ANSYS,构建了电容层析成像(ECT)系统平面3×4电容传感器阵列三维模型。介绍了平面电容传感器阵列结构并分析了其测量原理。对电容进行了仿真计算。仿真与实验进行了对比,证明了仿真模拟的可行性。通过仿真计算... 详细信息

通过电磁场有限元分析软件ANSYS,构建了电容层析成像(ECT)系统平面3×4电容传感器阵列三维模型。介绍了平面电容传感器阵列结构并分析了其测量原理。对电容进行了仿真计算。仿真与实验进行了对比,证明了仿真模拟的可行性。通过仿真计算电容值,研究了材料与电极间距和材料厚度对电容值的影响。计算了电极对长度和宽度方向的检测深度。通过ANSYS模拟,为损伤检测的特征提取和逆问题图像重构提供了仿真数据。

关键词： ANSYS 平面电容传感器阵列三维仿真

Ubiquitin-specific protease 1 facilitates tumor immune escape from natural killer cells and predicts the prognosis in small cell lung cancer

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Oncology research 2025年第1期33卷 213-224页

作者： Shiqin Jiang Yichun tang Feng Ma Yuchun Niu Lei Sun Department of Clinical Pharmacy Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine Shenzhen 518104 China. Department of Pathology Zhujiang Hospital Southern Medical University Guangzhou 510280 China. Department of Radiation Oncology The First People's Hospital of Foshan Foshan 528000 China. Department of Oncology The First Affiliated Hospital of Jinan University Jinan University Guangzhou 510630 China. Department of Oncology The First Dongguan Affiliated Hospital Guangdong Medical University Dongguan 523721 China.

Objective:Small cell lung cancer (SCLC) is commonly recognized as the most fatal lung cancer type. Despite substantial advances in immune checkpoint blockade therapies for treating solid cancers, their benefits are limited to a minority of patients with SCLC. In the present study, novel indicators for predicting the outcomes and molecular targets for SCLC treatment were elucidated.Methods:We conducted bioinformatics analysis to identify the key genes associated with tumor-infiltrating lymphocytes in SCLC. The functional role of the key gene identified in SCLC was determined both and .Results:A significant correlation was observed between patient survival and CD56dim natural killer (NK) cell proportion. Furthermore, we noted that the hub gene ubiquitin-specific protease 1 (USP1) is closely correlated with both CD56dim NK cells and overall survival in SCLC. Bioinformatics analysis revealed that USP1 is upregulated in SCLC. In addition, gene set enrichment analysis revealed that USP1 overexpression hinders NK cell-mediated immune responses. By co-cultivating NK-92 cells with SCLC cells, we demonstrated that NK cell cytotoxicity against SCLC could be improved either via USP1 knock-down or pharmacological inhibition. Furthermore, using a nude-mice xenograft tumor model, we noted that USP1 inhibition effectively suppressed tumor proliferation and increased the expression of NK cell-associated markers.Conclusions:Our study findings highlight the importance of NK cells in regulating SCLC. USP1 overexpression can inhibit NK cell-mediated immunity; therefore, USP1 may serve not only as a prognostic biomarker but also as a potential molecular target of SCLC therapy.

关键词： Immune escape Natural killer (NK) cell Prognosis Small cell lung cancer (SCLC) Ubiquitin-specific protease 1 (USP1)

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo

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Neural Regeneration Research 2025年第9期20卷 2633-2644页

作者： Zhimin Long Chuanhua Ge Yueyang Zhao Yuanjie Liu Qinghua Zeng Qing tang Zhifang Dong Guiqiong He Institute of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqingChina Department of Anatomy Chongqing Medical UniversityChongqingChina Department of Physiology Chongqing Medical UniversityChongqingChina Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina National Clinical Research Center for Child Health and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque ***,resto ring normal lysosomal function and rebalancing lysosomal acidification in neurons in the brain may be a new treatment strategy for Alzheimer's *** acetylation/deacetylation plays a central role in lysosomal ***,we show that inhibiting the classic microtubule deacetylase histone deacetylase 6 with an histone deacetylase 6 shRNA or thehistone deacetylase 6 inhibitor valproic acid promoted lysosomal reacidification by modulating V-ATPase assembly in Alzheimer's *** rthermore,we found that treatment with valproic acid markedly enhanced *** clearance of amyloid-βaggregates,and ameliorated cognitive deficits in a mouse model of Alzheimer's *** findings demonstrate a previously unknown neuroprotective mechanism in Alzheimer's disease,in which histone deacetylase 6 inhibition by valproic acid increases V-ATPase assembly and lysosomal acidification.

关键词： Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPase

Boosting Photocatalytic Performance of Cu-Mn Co-doped CeO_(2) Nanoparticles for Tetracycline Degradation

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 42-48页

作者： XU Rongqi MI Jianxin WANG Shulin XU Man ZHU Li BAI Lei tang Dandan LEI Yu Engineering Research Center of Environmental Materials and Membrane Technology of Hubei Province School of Materials Science and EngineeringWuhan Institute of TechnologyWuhan 430205China Shaanxi Coal Chemical Industry Technology Research Institute Co. Ltd.Xi’an 710100China

Cu-Mn co-doped CeO_(2) photocatalyst was successfully synthesized by the sol-gel method to assess its capability in degrading *** and TEM results showed that Cu and Mn were successfully co-doped into CeO_(2) without forming heterostructure,XPS and photoelectrochemical results revealed that Mn ions doping amplified the generation of photo-induced charge carriers,while Cu ions doping significantly facilitated the interfacial charge transfer ***,the optimized Cu3Mn2CeO_(2) nanoparticles exhibited the highest TC removal efficiency,achieved a rate of 78.18%and maintained a stable cycling performance.

关键词： photocatalyst co-doped charge separation water treatment

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陶瓷基复合材料粘接构件超声特征研究方法

测控技术 2021年第5期40卷 80-85页

作者：张玉燕李万达杨若然温银堂燕山大学测试计量技术及仪器河北省重点实验室河北秦皇岛066004 燕山大学电气工程学院河北秦皇岛066004

新型航天器机体外层陶瓷基复合材料隔热构件在粘贴过程中会产生缺陷,不利于航天器的飞行安全。针对一种陶瓷基多孔复合材料粘接结构构件,利用自主研制的超声C扫描自动检测系统,研究构件粘接层缺陷的超声检测特征。考虑材料多孔性和各向... 详细信息

新型航天器机体外层陶瓷基复合材料隔热构件在粘贴过程中会产生缺陷,不利于航天器的飞行安全。针对一种陶瓷基多孔复合材料粘接结构构件,利用自主研制的超声C扫描自动检测系统,研究构件粘接层缺陷的超声检测特征。考虑材料多孔性和各向异性会导致超声数据多噪音,采用自适应小波阈值算法对超声信号进行去噪,从而提高透射声波的信噪比。在此基础上,提出采用Hilbert-Huang变换(HHT)和伪Wigner-Ville分布(PWVD)相结合的方法对透射声波进行时频分析,得到时间、频率和幅值的三维分布,从而获得超声透射波最大幅值和对应的时间和频率。通过对比缺陷处与非缺陷处超声透射信号的时频域分布,揭示了该类新型陶瓷基复合材料粘接缺陷对超声信号的影响特点。

关键词：陶瓷基复合材料构件 C扫描粘接缺陷检测 HHT时频分析伪Wigner-Ville分布(PWVD)