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Miura-ori enabled stretchable circuit boards

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npj Flexible Electronics 2021年第1期5卷 9-17页

作者： Yongkai Li weixuan liu Yang Deng Wei Hong Hongyu Yu Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongChina Smart Manufacturing Thrust Systems HubThe Hong Kong University of Science and Technology(Guangzhou)NanshaGuangzhouGuangdongChina Department of Mechanics and Aerospace Engineering Southern University of Science and TechnologyShenzhenGuangdongChina

Origami,an ancient form of papercraft,provides a way to develop functional structures for engineering *** this paper,we report an approach to design and manufacture a stretchable circuit board(SCB)with origami *** benefits of developable,flat-foldable,and rigid-foldable origami-based structures as SCBs are discussed,and a representative structure,Miura fold(or Miura-ori),is chosen to be *** the constraints induced by the mounted components’dimensions,the Miura-ori structures for specific applications can be *** propose three methods for better fabrication,including direct folding,stiffness modification,and kirigami enhancement,to improve a planar sheet’s foldability.A wearable ECG(electrocardiogram)system based on MO-SCB(Miura-ori enabled SCB)technology is built,and the stretchable portion is made of commercial FPCBs(flexible printed circuit board),providing desired stretchability and *** proposed technology routine is compatible with industrial production and may pave the application of stretchable electronics.

关键词： Miura mounted dimensions

Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis:Toward a precision therapy

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Bioactive Materials 2023年第12期30卷 169-183页

作者： weixuan liu Anqi liu Xujun Li Ziyang Sun Zhenghua Sun Yaru liu Gang Wang Dan Huang Hao Xiong Shiyang Yu Xintao Zhang Cunyi Fan Department of Sports Medicine Peking University Shenzhen HospitalShenzhen Peking University-The Hong Kong University of Science and Technology Medical CenterShenzhen518036China Shanghai Engineering Research Center for Orthopedic Material Innovation and Tissue Regeneration Shanghai201306China Department of Orthopedics Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200233China Department of Orthodontics Shanghai Stomatological Hospital&School of StomatologyFudan UniversityShanghai200001China Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases Fudan UniversityShanghai200001China Minhang Hospital Fudan UniversityShanghai201199China

Osteoarthritis(OA)is the most common disabling joint disease with no effective disease modifying *** vesicles released by several types of mesenchymal stem cells could promote cartilage repair and ameliorate OA pathology in animal models,representing a novel therapeutic *** this study,we demonstrated that extracellular vesicles derived from human umbilical cord mesenchymal stem cells(hUC-EVs)could maintain chondrocyte homeostasis and alleviate OA,and further revealed a novel molecular mechanism of this therapeutic ***-223,which could directly bind with the 3′UTR of NLRP3 mRNA,was found to be a key miRNA for hUC-EVs to exert beneficial effects on inflammation inhibiting and cartilage *** enhancing the effect on mitigating osteoarthritis,exogenous miR-223 was loaded into hUC-EVs by electroporation,and a collagen II-targeting peptide(WYRGRL)was modified onto the surface of hUC-EVs by genetic engineering to achieve a more targeted and efficient RNA delivery to the *** dual-engineered EVs showed a maximal effect on inhibiting the NLRP3 inflammasome activation and chondrocyte pyroptosis,and offered excellent results for the treatment of *** study provides a novel theoretical basis and a promising therapeutic strategy for the application of engineered extracellular vesicles in OA treatment.

关键词： Osteoarthritis Extracellular vesicles NLRP3 inflammasome Pyroptosis Cartilage-targeting

Bone marrow edema in a postpartum female following ankle sprain: a case report

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World Journal of Emergency Medicine 2024年第4期15卷 325-327页

作者： Peng Zhang Junjie Zhang Peng Chen Jianjing Lin Jiang Guo weixuan liu Zhiwen Luo Qing Wang Xintao Zhang Department of Sports Medicine Peking University Shenzhen HospitalShenzhen 518000China Department of Sports Medicine Huashan HospitalFudan UniversityShanghai 200040China Department of Orthopaedics Kunshan Hospital of Traditional Chinese MedicineKunshan 215300China

Bone marrow edema(BME)is characterized by an accumulation of interstitial fluid within the bone marrow,the cancellous,hematopoietic compartment within bones.[1]BME is divided into two principal categories:idiopathic or primary BME,with an unknown etiology,and secondary BME,which occurs as a result of an identifiable underlying pathology.[2]Although the prevalence of BME is not limited to specific demographic parameters,it shows a predilection for males or individuals assigned male at birth,predominantly aged between the ages of 30 and 60 years,especially in cases of bone marrow edema syndrome(BMES),a rare idiopathic variant.[3]The etiological spectrum of BME is diverse,including oncological entities(such as acute myeloid leukemia and osteosarcoma),degenerative diseases(such as osteoarthritis),infectious processes(osteomyelitis),ischemic conditions(avascular necrosis),metabolic dysfunctions(osteoporosis),inflammatory disorders(rheumatoid arthritis),and traumatic injuries(such as stress fractures).[1,2]Clinically,BME primarily manifests as localized pain,often accompanied by joint effusion and warmth near the affected *** protocols typically include physical examination,serological assays,bone marrow biopsies,dual-energy X-ray absorptiometry(DEXA)scans,magnetic resonance imaging(MRI),and ultrasonography,with computed tomography(CT)scans and radiographs being less effective.

关键词： edema injuries female

Mother—My First Teacher

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Women of China 1996年第9期 31-33页

作者： CHEN weixuan HONG liu

MY first teacher was my mother. It was she who taught me to read. It was she who planted in my heart a profound love of Chinese literature. She was also the one who set me on the road to independence. Today, I am teaching others—I am an associate professor of Chinese language and literature at the Central Institute for Finance and Banking, a member of the Chinese Poetry Society, a member of

关键词： Mother My First Teacher

B型脑钠肽、同型半胱氨酸水平及踝臂指数在老年皮层下动脉硬化性脑病患者中的变化研究

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中国医药科学 2013年第22期3卷 215-216页

作者：刘蔚萱江苏省常德市第一人民医院老年科江苏常德415000

目的探讨B型脑钠肽（BNP）、同型半胱氨酸（Hey）水平和踝臂指数（ABI）在老年皮层下动脉硬化性脑病患者中的变化及其关系，为更好的临床治疗提供参考。方法选取2010年9月。2012年12月我院收治的108例老年皮层下动脉硬化性脑病患者，对... 详细信息

目的探讨B型脑钠肽（BNP）、同型半胱氨酸（Hey）水平和踝臂指数（ABI）在老年皮层下动脉硬化性脑病患者中的变化及其关系，为更好的临床治疗提供参考。方法选取2010年9月。2012年12月我院收治的108例老年皮层下动脉硬化性脑病患者，对其Hey、BNP水平和ABI进行测定，并根据其Hey水平将患者分为Hcy正常组和Hey增高组。观察分析两组患者的BNP、ABI、各项生化指标、动脉硬化指标的差异。结果108例患者中有82例患者的Hey水平升高，26例患者的水平Hey水平正常。与Hey正常组相比，Hey增高组患者的BNP显著升高（P〈0．05），ABI显著减低（P〈0．05）；两组患者的其他各项生化指标和动脉硬化指标差异无统计学意义（P〉0．05）。结论大多数老年皮层下动脉硬化性脑病患者的Hey、BNP、ABI水平会有显著变化，且三者有一定的相关性。

关键词： B型脑钠肽同型半胱氨酸踝臂指数老年皮层下动脉硬化性脑病

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基于JAVA的防围标串标技术及应用

信息技术与信息化 2023年第3期 85-88页

作者：刘伟轩山西焦煤物资装备有限公司山西太原030000

针对招投标过程中严重影响行业市场良性竞争的围标串标行为,提出一种基于Java桌面应用程序的识别围标串标技术。首先对投标计算机的硬件、网络信息进行对比,然后利用杰拉德系数分析法对投标文件相似度进行分析,根据对比分析结果对疑似... 详细信息

针对招投标过程中严重影响行业市场良性竞争的围标串标行为,提出一种基于Java桌面应用程序的识别围标串标技术。首先对投标计算机的硬件、网络信息进行对比,然后利用杰拉德系数分析法对投标文件相似度进行分析,根据对比分析结果对疑似围标串标行为进行预警,同时使用多重加密方式防止信息篡改,进而为评标工作提供准确的数据支持,辅助评标专家智能化评标,促进招投标行业的健康发展。实验结果表明,所提技术可高效准确识别围标串标行为,具有较高的实用价值。

关键词：电子招投标硬件分析杰拉德系数围标串标

基于尖点突变理论的煤矿事故中个体心理状态演变过程研究

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煤矿安全 2017年第3期48卷 242-244,248页

作者：吕帆李新春刘炜烜中国矿业大学管理学院江苏徐州221116

煤矿事故中个体心理状态会极大影响救援工作的有效性,了解其演变过程具有重要意义。根据尖点突变理论和事故中个体心理状态发生的突变情况,构建了尖点突变模型,并绘出平衡曲面进行研究分析。通过实例分析阐述了煤矿事故中个体心理状态... 详细信息

煤矿事故中个体心理状态会极大影响救援工作的有效性,了解其演变过程具有重要意义。根据尖点突变理论和事故中个体心理状态发生的突变情况,构建了尖点突变模型,并绘出平衡曲面进行研究分析。通过实例分析阐述了煤矿事故中个体心理状态的演变过程,发现了不安心理和周边环境对心理状态的影响原理,提供了通过控制个体心理状态来降低事故灾害性的有效途径。

关键词：煤矿事故个体心理状态突变理论不安心理突变行为

基于HYDRUS-2D的负压微润灌土壤水分运动模拟

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农业机械学报 2021年第8期52卷 287-296页

作者：徐俊增刘玮璇卫琦王可纯王海渝周姣艳河海大学农业科学与工程学院南京210098 河海大学水文水资源与水利工程科学国家重点实验室南京210098 昆山市城市水系调度与信息管理处昆山215300

为研究负压微润灌不同技术参数组合下的土壤水分运动过程,以土箱试验实测含水率为依据,构建并验证了基于HYDRUS-2D的负压微润灌土壤水分运动反演模型,并结合反演模型对负压微润灌多种组合情景的土壤湿润体模拟结果和典型设施作物根系分... 详细信息

为研究负压微润灌不同技术参数组合下的土壤水分运动过程,以土箱试验实测含水率为依据,构建并验证了基于HYDRUS-2D的负压微润灌土壤水分运动反演模型,并结合反演模型对负压微润灌多种组合情景的土壤湿润体模拟结果和典型设施作物根系分布特征及需水规律,探究适宜于不同设施作物的负压微润灌技术参数组合。结果表明:采用HYDRUS-2D反演模型能够较好地模拟负压微润灌不同供水水头条件下的土壤湿润体特征,土壤湿润距离(水平距离、垂直向上距离和垂直向下距离)、含水率及累积入渗量模拟值与实测结果之间的决定系数和NSE分别达到0.98和0.77以上。试验及模拟结果均表明,负压微润灌条件下供水水头与土壤含水率、累积入渗量及不同方向的湿润距离均呈负相关关系。此外,基于反演模型对负压微润灌不同湿润体的情景模拟结果和典型设施作物根系分布特征及需水规律,拟定了不同设施作物适宜的负压微润灌技术参数范围。本研究对农业生产中负压微润灌技术参数的选择及新型节水微润灌技术的推广具有指导意义。

关键词：负压微润灌湿润体特征土壤水分入渗 HYDRUS-2D模型

基于数字孪生技术的网络运维管理系统架构研究

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信息与电脑 2021年第7期33卷 16-18页

作者：刘伟轩刘晓莲山西艾德信息技术有限公司山西太原030006

为解决传统管理系统在应用中存在耗时长的问题,笔者提出一种基于数字孪生技术的网络运维管理系统,首先分析了基于数字孪生技术的网络运维管理系统硬件架构设计,进而分析了基于数字孪生技术的网络运维管理系统软件架构设计,最后进行了对... 详细信息

为解决传统管理系统在应用中存在耗时长的问题,笔者提出一种基于数字孪生技术的网络运维管理系统,首先分析了基于数字孪生技术的网络运维管理系统硬件架构设计,进而分析了基于数字孪生技术的网络运维管理系统软件架构设计,最后进行了对比实验。实验结果证明,新的管理系统恢复网络运行环境正常运行的时间明显缩短,能够有效提高管理效率。

关键词：数字孪生技术网络运维管理系统