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Potential benefits,mechanisms,and uncertainties of convalescent plasma therapy for COVID-19

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Blood Science 2020年第3期2卷 71-75页

作者： weiqian dai Haihui Gu Sha Hao State Key Laboratory of Experimental Hematology Institute of Hematology and Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjinChina Department of Transfusion Medicine Changhai HospitalThe Second Military Medical UniversityShanghaiChina

The outbreak of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in China led to a public health emergency of international concern,putting all health organizations on high alert in the beginning of *** virus disease 2019(COVID-19)is highly infectious and has resulted in thousands of deaths which exceeded that of the SARS coronavirus(SARS-CoV)outbreak back in 2002 and 2003 in ***,the number of diagnosed patients,patients who are suspected to have contracted the disease,and deaths are increasing ***,effective drugs and vaccines to combat SARS-CoV-2 are still *** plasma,a seemingly successful treatment for COVID-19 patients,proved to be of huge value in terms of saving severely ill *** review introduces the reported effects,potential mechanisms,and future uncertainties of convalescent plasma therapy in the treatment of COVID-19 patients,in the hopes that it will provide useful information for relevant physicians and researchers.

关键词： SARS-CoV-2 COVID-19 convalescent plasma mechanisms adverse effects

中国210例软骨发育不全患儿临床遗传特征分析及生长发育曲线探索

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中华儿科杂志 2020年第6期58卷 461-467页

作者：代伟倩顾学范余永国上海交通大学医学院附属新华医院儿内分泌/遗传科 200092

目的总结携带成纤维细胞生长因子受体3(FGFR3)基因变异的中国软骨发育不全(ACH)患儿的临床表现及遗传学特征,拟合中国ACH患儿身高生长百分位参照值及身高与年龄生长曲线,为中国ACH患儿提供更为实用的生长评价工具。方法横断面研究。于2... 详细信息

目的总结携带成纤维细胞生长因子受体3(FGFR3)基因变异的中国软骨发育不全(ACH)患儿的临床表现及遗传学特征,拟合中国ACH患儿身高生长百分位参照值及身高与年龄生长曲线,为中国ACH患儿提供更为实用的生长评价工具。方法横断面研究。于2019年7月至2020年1月由上海交通大学医学院附属新华医院儿内分泌/遗传科组织开展,在全国范围内入组210例FGFR3基因检测确诊的ACH患儿(男110例、女100例),收集患儿临床资料及身高数据;分析中国ACH人群的临床特征及遗传学特点并依据0~12岁患儿身高(2岁以下测量身长)测量数据,应用LMS方法对数据进行拟合修匀,分别获得所需要的百分位并绘制ACH患儿身高与年龄生长曲线图。结果210例中国ACH患儿(0~14岁)主要临床表现典型包括非匀称性矮小206例(98.1%),手指短小且呈"三叉戟"样191例(90.9%),小腿弯曲156例(74.3%),头颅大且伴前额突出205例(97.6%);210例患儿智力及体力发育均良好;172例(81.9%)ACH患儿发生并发症,主要的并发症是脊柱畸形121例(70.3%)和胸廓窄79例(45.9%)。高达98.6%(207/210)的患儿携带FGFR3杂合热点变异(第1138位核苷酸点突变)导致发生的G380R氨基酸替换。ACH男、女患儿生长模式与正常儿童群体中观察到的生长模式存在明显不同(t=9.849、9.596,P均<0.01);出生时患儿的平均身长(男49.2 cm,女48.4 cm)分别为正常儿童的-1.22 s和-2 s,随着年龄增长ACH患儿与正常儿童的身高差距逐渐拉大,至12岁时患儿平均身高(男113.7 cm,女112.4 cm)分别为正常儿童标准的-5.23 s和-6.15 s。结论中国FGFR3基因变异致ACH患儿的临床表现典型主要为非匀称性矮小和颅面部发育异常、遗传特征主要为携带G380R热点变异且首次拟合中国0~12岁ACH患儿身高与年龄生长曲线图及其身高百分位数对于评估患儿的生长情况、监测可能影响其生长的因素、估计其最终身高以及评估促生长治疗的疗效提供实用的生长评价工具。

关键词：软骨发育不全生长曲线表发育障碍侏儒症

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MIMO雷达性能分析

电子科技 2009年第10期22卷 56-59,81页

作者：戴伟倩西安电子科技大学电子工程学院陕西西安710071

研究了MIMO雷达目标位置回波的模糊函数。比较了相关目标模糊函数和非相关目标模糊函数的性能,介绍了MIMO雷达回波信号模型的基本原理。仿真证明,对于MIMO雷达相关处理性能优于非相关处理性能,能提高目标位置估计的分辨力。采用相关处... 详细信息

研究了MIMO雷达目标位置回波的模糊函数。比较了相关目标模糊函数和非相关目标模糊函数的性能,介绍了MIMO雷达回波信号模型的基本原理。仿真证明,对于MIMO雷达相关处理性能优于非相关处理性能,能提高目标位置估计的分辨力。采用相关处理模糊函数的定位仍受噪声影响,对均方定位误差性能进行了分析。

关键词： MIMO雷达模糊函数信号模型检测性能

“One stone, two birds”: Salt template enabling porosity engineering and single metal atom coordinating toward high-performance zinc-ion capacitors

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Journal of Energy Chemistry 2025年第1期100卷 637-645页

作者： Chunliu Zhu Huanyu Liang Ping Li Chenglong Qiu Jingyi Wu Jingwei Chen weiqian Tian Yue Zhu Zhi Li Huanlei Wang School of Materials Science and Engineering Ocean University of China Department of Chemical and Materials Engineering University of Alberta

Zinc-ion hybrid capacitors （ZIHCs） have received increasing attention as energy storage devices owing to their low cost,high safety,and environmental ***,their progress has been hampered by low energy and power density,as well as unsatisfactory long-cycle stability,mainly due to the lack of suitable electrode *** this context,we have developed manganese single atoms implanted in nitrogen-doped porous carbon nanosheets （MnSAs/NCNs） using a metal salt template method as cathodes for *** metal salt serves a dual purpose in the synthesis process:It facilitates the uniform dispersion of Mn atoms within the carbon matrix and acts as an activating agent to create the porous *** applied in ZIHCs,the MnSAs/NCNs electrode demonstrates exceptional performance,including a high capacity of 203 m Ah g-1,an energy density of 138 Wh kg-1at 68 W kg-1,and excellent cycle stability with 91%retention over 10,000 *** calculations indicate that the introduced Mn atoms modulate the local charge distribution of carbon materials,thereby improving the electrochemical *** work demonstrates the significant potential of carbon materials with metal atoms in zinc-ion hybrid capacitors,not only in enhancing electrochemical performance but also in providing new insights and methods for developing high-performance energy storage devices.

关键词： Zinc ion hybrid capacitors Cathodes Carbon materials Heteroatoms Single atoms

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柔性直流配电技术的发展与现状

湖北电力 2019年第1期43卷 18-24页

作者：叶庞琪陈堃代维谦国网湖北省电力有限公司电力科学研究院湖北武汉430077 国网湖北省孝感供电公司检修分公司湖北孝感432100

本文通过与交流配电网的对比,结合高压直流输电技术的发展,分析了柔性直流配电网的技术优势,并进一步对目前柔性直流配电研究中诸如电压等级、拓扑结构、关键设备、控制保护等关键技术进行了分析,结合中国目前已有的典型示范工程,对柔... 详细信息

本文通过与交流配电网的对比,结合高压直流输电技术的发展,分析了柔性直流配电网的技术优势,并进一步对目前柔性直流配电研究中诸如电压等级、拓扑结构、关键设备、控制保护等关键技术进行了分析,结合中国目前已有的典型示范工程,对柔性直流配电技术的研究现状、重点方向进行了介绍。

关键词：柔性直流配电配电网高压直流输电拓扑结构

组织认同对高校图书馆馆员创新行为的影响研究

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农业图书情报学刊 2018年第4期30卷 5-12页

作者：戴伟茜黄思慧包平南京农业大学信息管理系江苏南京210095

以组织认同为出发点,对高校图书馆馆员创新行为的影响路径进行研究,分析组织认同各因素对馆员创新行为的影响程度。通过将相关理论、研究成果与专家访谈相结合,提出图书馆组织认同以及馆员创新行为量表。将组织认同分为组织认知,组织归... 详细信息

以组织认同为出发点,对高校图书馆馆员创新行为的影响路径进行研究,分析组织认同各因素对馆员创新行为的影响程度。通过将相关理论、研究成果与专家访谈相结合,提出图书馆组织认同以及馆员创新行为量表。将组织认同分为组织认知,组织归属,领导认知,同事关系四个维度;将馆员创新行为分为创新想法产生,创新想法推动,创新行为实施三个维度;继而以调查问卷的形式,选取不同类型高校图书馆馆员为调研对象,通过SPSS和AMOS软件进行实证分析发现:组织归属和同事关系与馆员创新行为之间有显著路径系数,其中同事关系对馆员创新行为影响最大;领导认知、组织认知与组织归属、同事关系之间有显著路径系数。

关键词：高校图书馆组织氛围组织认同馆员创新行为影响研究

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高压直流输电技术发展及其工程应用

湖北电力 2018年第4期42卷 1-6页

作者：陈堃宋宇代维谦肖繁陈汝斯国网湖北省电力有限公司电力科学研究院湖北武汉430077 国网湖北省电力有限公司检修公司湖北武汉430050 国网湖北省孝感供电公司检修分公司湖北孝感432100

从高压直流输电技术的发展历程出发,阐述了近30年来高压直流输电技术在中国得到大规模推广和应用的原因,然后在简述柔性直流输电技术原理的基础上比对了传统直流与柔性直流两者的主要区别,列举了近年来中国的典型高压直流输电工程案例,... 详细信息

从高压直流输电技术的发展历程出发,阐述了近30年来高压直流输电技术在中国得到大规模推广和应用的原因,然后在简述柔性直流输电技术原理的基础上比对了传统直流与柔性直流两者的主要区别,列举了近年来中国的典型高压直流输电工程案例,并对其中的关键技术进行了概述,对高压直流输电技术未来的推广应用进行了展望。

关键词：直流输电柔性直流输电换流技术柔直换流站

Studies on relationships between air pollutants and allergenicity of Humulus Scandens pollen collected from different areas of Shanghai

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Journal of Environmental Sciences 2020年第9期32卷 43-48页

作者： Senlin Lu Chuanhe Yao Shumin Zhou Yichun Lin Luying Zhang Junyang Zeng Lanfang Rao Wei Zhang Yafeng dai Hong Li weiqian Wang Qingyue Wang School of Environmental and Chemical Engineering Shanghai UniversityShanghai 200444China Lab of Plant Cell Biology Shanghai Key Laboratory of Bio-Energy CropsSchool of Life SciencesShanghai UniversityShanghai 200444China Shandong University of Science and Technology Qingdao 266590China Chinese Research Academy of Environmental Sciences Beijing 100021China School of Science and Engineering Saitama UniversitySaitama 338-8570Japan

Pollen pollution and allergy are becoming prominent issues in ***,few studies on pollinosis have been *** an allergen in the atmosphere,allergenic Humulus scandens pollen was collected from four districts of Shanghai,including Wusong(WS),Jiading(KD),Xujiahui(XJH) and Songjiang(SJ).The mass concentrations of SO2,NO2,O3,PM10,and PM2.5(particulate matter with air dynamic diameter less than 10 and 2.5 um,respectively) near the four sampling sites were also recorded during Humulus scandens pollen *** allergenicity of the Humulus scandens pollen was assessed by using of a rat model and enzyme linked immunosorbent assay(ELISA).Relationships between the allergenicity and air pollutants were *** results demonstrated that the biological viability of the pollens collected from the four districts exhibited no significant *** and dot blotting results further demonstrated that the serum of sensitized rats exhibited much higher immune-reactive response than that of control *** blotting showed that the 15 KD(1 KD=1000 dalton) proteins of Humulus pollen led to the allergic *** allergenic intensity of Humulus pollen protein from different samples followed the pattern:WS> JD> XJ> *** was a negative relationship between the allergenicity of Humulus pollens and PM10(R=-0.99)/PM2.5(R=-0.73),and a positive relationship with O3(R=0.92).These data clearly showed that PM10 and PM2.5 could enhance Humulus pollen protein release,and 03 could aggravate the allergenicity of the Humulus pollen.

关键词： (ELISA) pollution China.

A High-Resolution Measurement Method for Inner and Outer 3D Surface Profiles of Laser Fusion Targets Using a Laser Differential Confocal–Atomic Force Probe Technique

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Engineering 2024年第10期41卷 51-60页

作者： weiqian Zhao Zihao Liu Lirong Qiu MIIT Key Laboratory of Complex-Field Intelligent Exploration School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China

The high-resolution and nondestructive co-reference measurement of the inner and outer threedimensional(3D)surface profiles of laser fusion targets is difficult to *** this study,we propose a laser differential confocal(LDC)–atomic force probe(AFP)method to measure the inner and outer 3D surface profiles of laser fusion targets at a high *** method utilizes the LDC method to detect the deflection of the AFP and exploits the high spatial resolution of the AFP to enhance the spatial resolution of the outer profile *** and co-reference measurements of the inner profile of a target were achieved using the tomographic characteristics of the LDC ***,by combining multiple repositionings of the target using a horizontal slewing shaft,the inner and outer 3D surface profiles of the target were obtained,along with a power spectrum assessment of the entire *** experimental results revealed that the respective axial and lateral resolutions of the outer profile measurement were 0.5 and 1.3 nm,while the respective axial and lateral resolutions of the inner profile measurement were 2.0 nm and approximately 400.0 *** repeatabilities of the rootmean-square deviation measurements for the outer and inner profiles of the target were 2.6 and 2.4 nm,*** believe our study provides a promising method for the high-resolution and nondestructive co-reference measurement of the inner and outer 3D profiles of laser fusion targets.

关键词： Laser fusion targets Laser differential confocal-atomic force probe High-resolution Nondestructive Co-reference