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Style-conditioned music generation with Transformer-GANs

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 106-120页

作者： weining WANG Jiahui LI Yifan LI Xiaofen XING School of Electronic and Information Engineering South China University of TechnologyGuangzhou 510600China

Recently,various algorithms have been developed for generating appealing ***,the style control in the generation process has been somewhat *** style refers to the representative and unique appearance presented by a musical work,and it is one of the most salient qualities of *** this paper,we propose an innovative music generation algorithm capable of creating a complete musical composition from scratch based on a specified target style.A style-conditioned linear Transformer and a style-conditioned patch discriminator are introduced in the *** style-conditioned linear Transformer models musical instrument digital interface(MIDI)event sequences and emphasizes the role of style ***,the style-conditioned patch discriminator applies an adversarial learning mechanism with two innovative loss functions to enhance the modeling of music ***,we establish a discriminative metric for the first time,enabling the evaluation of the generated music’s consistency concerning music *** objective and subjective evaluations of our experimental results indicate that our method’s performance with regard to music production is better than the performances encountered in the case of music production with the use of state-of-the-art methods in available public datasets.

关键词： Music generation Style-conditioned Transformer Music emotion

A smart hybrid memory scheduling approach using neural models

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Science China(Information Sciences) 2024年第4期67卷 333-334页

作者： Yanjie ZHEN Huijun ZHANG Yongheng DENG weining CHEN Wei GAO Ju REN Yu CHEN Department of Computer Science and Technology Tsinghua University China Huaneng Clean Energy Research Institute

Traditional dynamic random access memory is limited by its low capacity and high cost because of the increasing demand for the memory capacity of applications. Hybrid memory architectures, including new memory hardwar... 详细信息

关键词： Cost reduction

Traceless photodegradable polymer cocoons for universal protein delivery and light-controlled gene editing

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Science China Chemistry 2024年第2期67卷 664-676页

作者： Huaibin Yu Meron Tsegay Kifle Lili Chen Feihong Xiong Yan Zhang Shangbang Gao Wei Hou Shuliang Chen weining Zhao Yuzhou Wu Hubei Engineering Research Center for Biomaterials and Medical Protective Materials Hubei Key Laboratory of Bioinorganic Chemistry&Materia MedicaKey Laboratory of Material Chemistry for Energy Conversion and StorageMinistry of EducationSchool of Chemistry and Chemical EngineeringHuazhong University of Science and Technology(HUST)Wuhan430074China Zhengzhou Research Institute Harbin Institute of TechnologyZhengzhou450000China College of Life Science and Technology Huazhong University of Science and Technology(HUST)Wuhan430074China Institute of Medical Virology School of Basic Medical SciencesWuhan UniversityWuhan430071China College of Pharmacy Shenzhen Technology UniversityShenzhen518118China

Polymer conjugation was found highly valuable in clinic to improve the bioavailability of protein ***,it is still a tremendous challenge to achieve a complete release of original proteins from the conjugated hybrid under external stimulus to recover active proteins in the targeted ***,we report a general light-controlled protein delivery methodology by weaving a photodegradable polymer cocoon around proteins,which could reliably protect them from degradation in the dark while efficiently releasing them under illumination without any residual *** surface charge of the polymer shell is easily tunable to facilitate efficient cell *** versatility of this strategy is demonstrated by the delivery of the Cas9/sg RNA complex that realized light-controlled gene editing both in vitro and in vivo,and such repertoire is of particular value in regard to minimizing the off-target toxicity of CRISPR-Cas9-based gene therapy.

关键词： photodegradable polymer-protein conjugate protein delivery light control gene editing

Molecular compositions and sources of organic aerosols at a rural site on the Guanzhong Plain,Northwest China:The importance of biomass burning

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Particuology 2024年第6期89卷 44-56页

作者： Yali Liu Minxia Shen Haijiao Liu Wenting Dai weining Qi Yifan Zhang Lu Li Yue Cao Xin Wang Xiao Guo Yingkun Jiang Jianjun Li State Key Laboratory of Loess and Quaternary Geology Key Lab of Aerosol Chemistry and PhysicsInstitute of Earth EnvironmentChinese Academy of SciencesXi'an 710061China Xi'an Institute for Innovative Earth Environment Research Xi'an 710061China National Observation and Research Station of Regional Ecological Environment Change and Comprehensive Management in the Guanzhong Plain ShaanxiChina

The concentration of PM_(2.5)has considerably reduced in recent years,but remains relatively high in *** particular,the increasing contribution of organic compounds to PM_(2.5)generates popular pressure for further reductions,resulting in an urgent need to study organic aerosol(OA).To investigate the molecular composition and source contribution of OA in the rural area of the Guanzhong Plain,Northwest China,PM_(2.5)samples were collected during 3–23 August 2016 and 5–20 January 2017 and studied for more than 100 organic tracer *** mean concentration of total measured organic compounds is 662±296 ng/m^(3)in summer and 3258±1925 ng/m^(3)in *** is the most abundant single compound found throughout the sampling period,which is a crucial tracer for biomass burning emissions,preliminary suggesting that biomass burning is an essential source of *** summer,organic compounds such as lipid compounds,sugar compounds,and polycyclic aromatic hydrocarbons(PAHs),more come from higher plants,wood burning,vehicle exhausts,plastic waste,and other direct emission *** PAHs(OPAHs),nitrophenols,and phthalic acids more come from the atmosphere through the oxidation reaction of aromatic precursors,especially photochemical ***,in winter,most of the increases in concentrations of organic compounds are attributed to biomass *** analysis of a haze event(14–19 January 2017)during the winter sampling period shows that the increases in the concentration of organic compounds are unaccompanied by strong secondary formation under lower relative humidity(49.1%±13.5%).The main reason for the growth of OA in this haze event is the accumulation of primary OA(POA).The source apportionment by the positive matrix factorization(PMF)model shows that biomass burning(37.1%)is the primary source of OA in the rural regions of the Guanzhong Plain,especially in winter(40.6%).The contribution of secondary formation decreases from 26.0%in summer t

关键词： Organic aerosol Molecular composition Seasonal variation Source apportionment Guanzhong Plain

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基于超亲水纳米通道的智能可控微反应器

高等学校化学学报 2021年第4期42卷 1276-1283页

作者：汪灿王殿宇苗伟宁田野中国科学院理化技术研究所中国科学院仿生材料与界面科学重点实验室北京100190 中国科学院大学北京100049 北京航空航天大学化学学院北京100191

对阳极氧化铝(Anodic Alumina Oxide,AAO)多孔膜进行低温空气等离子体处理得到超亲水纳米通道.在此基础上引入油溶性铁磁流体(Ferrofluid),通过调节外磁场的方向和强度构建出智能可控微反应器.该智能微反应器具有多梯度门控、高电流门... 详细信息

对阳极氧化铝(Anodic Alumina Oxide,AAO)多孔膜进行低温空气等离子体处理得到超亲水纳米通道.在此基础上引入油溶性铁磁流体(Ferrofluid),通过调节外磁场的方向和强度构建出智能可控微反应器.该智能微反应器具有多梯度门控、高电流门控比、长期循环稳定性的特点.将其分别用于均相和非均相反应中,采用荧光分光光度计和扫描电子显微镜等手段进行表征.结果表明,不同门控状态下反应产物具有不同的产量和结构,在微反应器的可控反应方面具有良好的应用前景.

关键词：超亲水纳米通道微反应器梯度门控磁流体

Multi-omics analyses of G6PD deficiency variants in Chinese population

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Journal of Genetics and Genomics 2024年第1期51卷 100-104页

作者： He Ji Jiahuan Chen Peide Huang Zhimin Feng weining Hu Mengyao Dai Xiaohui Sun Xiao Jin Guangquan Chen Guang Ning Lin Li Weiqing Wang Yanan Cao Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesNational Clinical Research Centre for Metabolic DiseasesState Key Laboratory of Medical GenomicsResearch Unit of Clinical and Basic Research on Metabolic Diseases of Chinese Academy of Medical SciencesRuijin Yangtze River Delta Health InstituteWuxi Branch of Ruijin HospitalRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China National Research Center for Translational Medicine National Key Scientific Infrastructure for Translational MedicineShanghai Jiao Tong UniversityShanghai 200240China SJTU-BGI Innovation Research Center Shanghai 200240China BGI-ShenZhen ShenzhenGuangdong 518083China

Glucose-6-phosphate dehydrogenase(G6PD)deficiency is one of the most prevalent hereditary and X-linked enzyme disorders caused by the pathogenetic G6PD(NM_001042351.2)variants(Yang et al.,2016).The clinical manifestations of G6PD deficiency offer a wide spectrum of diverse disease phenotypes(Hecker et al.,2013).Investigations of prevalence and molecular epidemiology demonstrate that G6PD deficiency affects over 400 milion individuals worldwide and leads to thousands of deaths annually(Mortality and Causes of Death,2015).

关键词： al. G6PD epidemiology

共建“一带一路”倡议的价值意蕴、建设成果与实践深化路径

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学术前沿 2024年第9期 106-111页

作者：欧阳纬柠马德里康普顿斯大学语言与文学学院

共建“一带一路”是我国在新的历史条件下实行高水平对外开放的重大举措。共建“一带一路”倡议的提出具有深刻的价值意蕴:反对逆全球化,加强各国经贸合作以及促进世界经济企稳回升;推动建立更加公正合理的全球治理体系;反对以资本为中... 详细信息

共建“一带一路”是我国在新的历史条件下实行高水平对外开放的重大举措。共建“一带一路”倡议的提出具有深刻的价值意蕴:反对逆全球化,加强各国经贸合作以及促进世界经济企稳回升;推动建立更加公正合理的全球治理体系;反对以资本为中心的现代化,推进以人民为中心的现代化;打破文明优劣论,促进文明平等交流互鉴。共建“一带一路”倡议提出以来,互联互通成效显著、贸易投资不断扩大、民生领域成果丰硕、全球治理持续改善。面向未来,共建“一带一路”倡议要持续打造亮点品牌、完善机制平台、统筹国内国际、加强话语建设。

关键词：共建“一带一路”倡议人类命运共同体全球治理经济全球化

基于搅拌摩擦加工技术的镁基复合材料研究进展

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机械工程学报 2024年第8期60卷 48-64页

作者：蹇文轩丛孟启雷卫宁江苏理工学院江苏省先进材料设计与增材制造重点实验室常州213001 江苏理工学院机械工程学院常州213001 江苏理工学院材料工程学院常州213001

镁与镁合金具有密度较小、比强度高和易加工等优点,随着科技水平的不断进步,航空航天等领域对镁合金的性能要求越来越高,镁基复合材料的发展与研究日益受到高度重视。而搅拌摩擦加工技术(Friction stir processing,FSP)由于具有低成本... 详细信息

镁与镁合金具有密度较小、比强度高和易加工等优点,随着科技水平的不断进步,航空航天等领域对镁合金的性能要求越来越高,镁基复合材料的发展与研究日益受到高度重视。而搅拌摩擦加工技术(Friction stir processing,FSP)由于具有低成本、高效率与绿色节能等独特优势,在航空航天与汽车等领域有着广阔的应用前景,已成为复合材料制造领域热门研究之一。近年来国内外研究人员尝试通过搅拌摩擦加工技术对不同类型的增强体与镁合金进行加工从而制备出了许多性能优异的复合材料。目前,主要增强体分为颗粒、纤维、石墨烯等,针对镁基复合材料搅拌摩擦加工的国内外研究进展展开综述,对适用于镁基复合材料的搅拌摩擦加工技术及其基础问题研究、加工工艺对复合材料组织与性能的影响等方面的重要研究成果进行举例和分析,进一步提出了镁基复合材料搅拌摩擦加工技术研究的发展方向,以期为搅拌摩擦技术在镁基材料加工领域的研究和应用发展起到指导作用。

关键词：镁基复合材料搅拌摩擦加工增强体复合增强

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装备群选择性维修决策与任务分配联合优化

兵工学报 2024年第2期45卷 407-416页

作者：马维宁胡起伟陈静贾希胜陆军工程大学石家庄校区河北石家庄050003

为满足作战任务需求,对装备群进行选择性维修的同时进行作战任务分配,可有效提高装备群的整体作战效益。针对选择性维修决策与任务分配独立优化的问题,以最大化任务完成概率为目标,构建装备群选择性维修决策与任务分配联合优化模型,引... 详细信息

为满足作战任务需求,对装备群进行选择性维修的同时进行作战任务分配,可有效提高装备群的整体作战效益。针对选择性维修决策与任务分配独立优化的问题,以最大化任务完成概率为目标,构建装备群选择性维修决策与任务分配联合优化模型,引入环境系数表征不同子任务的工作环境对单元状态的影响;通过求解马尔可夫模型得到单元的任务完成概率,进而得到子任务和整个任务的完成概率;采用基于随机密钥的遗传算法进行求解,分析环境系数对联合优化结果的影响,通过算例验证了模型和算法的有效性。研究结果表明:在选择性维修决策时考虑作战任务分配能够得到更优的结果;该模型可为战场环境下装备维修决策问题提供理论指导和技术支持。

关键词：装备群选择性维修任务分配联合优化遗传算法

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