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A High Performance 4H-SiC Normally-off VJFET

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A High Performance 4H-SiC Normally-off VJFET

Second-harmonic-assisted four-wave mixing in chip-based microresonator frequency comb generation

第4届国际电力电子及运动控制国际会议

作者： K.Tone P.Alexandrov L.Fursin m.weiner T.Burke SiCLAB ECE DepartmentRutgers University 94 Brett RoadPiscataway NJ 08854 USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA U.S. Army TACOm AMSTA-TR-R MS-121 Warren MI 48397USA

＜正＞ This paper presents the design, fabrication and characterisation of a high performance 4H-SiC normally-off, trenched and implanted vertical junction field-effect transistor （VJFET）- Devices with different trenched mesa widths were designed and their performance investigated. The fabricated VJFETs demonstrated a 3.9Ωresistance at VG=5V （with negligible gate current） and JD= 154A/cm2, corresponding to a low specific on-rcsistance of 3.7mΩcm2 for a normally-off VJFET blocking voltage up to 1,734V （at VG=OV）. The specific on-resistance is more than 200 times smaller than that of the theoretical limit of Si FETs. The figure-of-merit （FOm, Vbl2/RON-sp）, is equal to 815mW/cm2 for the demonstrated VJFET, substantially surpassing the best FOm of any kind of unipolar and bipolar SiC power switches.

关键词： SiC JFET oil-resistance figure-of-mcrit

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Light(Science & Applications) 2016年第1期5卷 79-87页

作者： Xiaoxiao Xue François Leo Yi Xuan Jose A Jaramillo-Villegas Pei-Hsun Wang Daniel E Leaird miro Erkintalo minghao Qi Andrew m weiner Department of Electronic Engineering Tsinghua UniversityBeijing 100084China School of Electrical and Computer Engineering Purdue University465 Northwestern AvenueWest LafayetteIN 47907-2035USA The Dodd-Walls Centre for Photonic and Quantum Technologies Department of PhysicsThe University of AucklandAuckland 1142New Zealand OPERA-photonics Universitélibre de Bruxelles(U.L.B.)50 Avenue F.D.RooseveltCP 194/5B-1050 BruxellesBelgium Birck Nanotechnology Center Purdue University1205 West State StreetWest LafayetteIN 47907USA Facultad de Ingenierías Universidad Tecnológica de PereiraPereira RIS 660003Colombia

Simultaneous Kerr comb formation and second-harmonic generation with on-chip microresonators can greatly facilitate comb self-referencing for optical clocks and frequency ***,the presence of both second-and third-order nonlinearities results in complex cavity dynamics that is of high scientific interest but is still far from being ***,we demonstrate that the interaction between the fundamental and the second-harmonic waves can provide an entirely new way of phase matching for four-wave mixing in optical microresonators,enabling the generation of optical frequency combs in the normal dispersion regime under conditions where comb creation is ordinarily *** derive new coupled time-domain mean-field equations and obtain simulation results showing good qualitative agreement with our experimental *** findings provide a novel way of overcoming the dispersion limit for simultaneous Kerr comb formation and second-harmonic generation,which might prove to be especially important in the near-visible to visible range where several atomic transitions commonly used for the stabilization of optical clocks are located and where the large normal material dispersion is likely to dominate.

关键词： four-wave mixing Kerr frequency comb microresonator second-harmonic generation

遗传性大疱性表皮松解症的眼部表现:美国本土大疱性表皮松解症登记处的结果

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世界核心医学期刊文摘（眼科学分册） 2005年第1期1卷 13-14页

作者：赵炜 Fine J.-D Johnson L.B weiner m Natl.Epidermolysis Bullosa R eg -istry Lexing tonKYUnited States.Dr.

Purpose To determine the frequency o f ocular manifesta-tions in inherited epidermolysis bullosa(EB)within the continental United States and to define the estimated cu-mulative risks of developing nonscarring(blisters or ero-sions)and scarring corneal manifestation s within each major EB subtype over *** Observational(cross-sectional and longitudinal).methods Up to 16years of longitudinal follow-up was conducted on 3,280consec-utively enrolled patients in the National EB Registry,an epidemiologic study funded by the Na tional Institutes of *** were stratified by majo r EB type and *** of occurrence were dete rmined for eight vari-ables(corneal erosions or blistering;corneal scarring;symblepharons;blepharitis;ectro pions;lacrimal duct ob-struction;impaired vision;blindn ess)by contingency ta-bles,and cumulative risks were generated by life table analysis *** The most common ocular manifestations were corneal erosio ns and ***-quencies mirrored relative severity of skin disease,with74.10%of all patients with recessiv e dystrophic EB,Hallopeau-Siemens(RDEB-HS )and 47.50%of all pa-tients with junctional EB,Herlitz(JEB-H)experiencing at least one *** frequencie s were noted for corneal *** and ectrop ions were most com-monly seen in inversa RDEB and JEB-H,*** was reported in 6.47%of RD EB-HS *** cumulative risks of nonscarring and scarring corneal lesions in JEB-H at age 5are 83.18%an d 27.08%and at age 25are 83.18%and 72.22%.With tim e,the cumu-lative risk of each in RDEB-HS approached that reported in JEB-H *** Ocular d isease activity,par-ticularly corneal,is common in some EB *** ophthalmologic examination should become an integral part of the management of all patients wit h inherited EB.

关键词：瘢痕化睑球粘连睑外翻角膜糜烂角膜病变泪小管累积危险度角膜瘢痕眼部病变瘢痕性

ACP-103,a potent 5-HT2A Receptor Inverse Agonist,as an Adjunctive Therapy in Schizophrenia

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ACP-103,a potent 5-HT2A Receptor Inverse Agonist,as an Adjun...

CT仿真支气管纤维镜指导下的经支气管行腔外纵隔及肺门病变细针抽吸活检

第十五届国际药理学大会

作者： Vanover Kimberly E. Lameh Jelveh Gardell Luis R. Ott Thomas R. ma Jian-Nong Burstein Ethan S. van Kammen Daniel Davis Robert E. weiner David m. Brann mark R. ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals

＜正＞ ACP- 103 is a potent and selective 5 - HT2A receptor inverse agonist,with nanomolar potency at 5 - HT2A receptors and 7-50 fold lower potency at 5 -HT2C receptors in a variety of in vitro assays. ACP - 103 lacks significant activity at D2 and over 50 other human receptors at concentrations up to 10 um. In mice. ACP - 103 was a potent inhibitor of head - twitch behaviors induced by 5 - HT2 agonist DOI, and enhanced haloperidol - or risperidone - mediated decreases in dizocilpine - or amphetamine - induced hyperactivity. ACP - 103 also reduced haloperidol - or risperidone - induced catalepsy and hyperprolactinemia in rats. The ability of ACP - 103 to reduce neuroleptic - induced side effects in animals was extended into the clinic. Initial clinical studies indicate that ACP - 103 was generally safe and well tolerated,had a long plasma half - life,and occupied 5 -HT2A receptors in human brain after oral administration. moreover. ACP- 103 administration reduced haloperidol - induced hyperprolactinemia in healthy volunteers,and haloperidol - induced akathisia in both healthy volunteers and schizophrenic subjects. Based on these observations. ACP - 103 may have potential as an adjunctive therapy in schizophrenia with a wide therapeutic index.

关键词：

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国际医学放射学杂志 2009年第3期 284-285页

作者： G.m.weiner K.Schulze B.Geiger H.Ebhardt K.J.Wolf T.Albrecht 周炳 Department of Radiology and Nuclear medicine Charité Campus Benjamin FranklinHindenburgdamm 3012200 BerlinGermany

目的比较采用传统的横断位CT扫描引导和采用仿真支气管镜术引导行经支气管细针抽吸活检术(TBNA)对于支气管纤维镜不可见的腔外纵隔和肺门病变的检出率,评价两种方法的命中率是否与每个个体病变的数目、大小和位置有关。方法本研究获得... 详细信息

目的比较采用传统的横断位CT扫描引导和采用仿真支气管镜术引导行经支气管细针抽吸活检术(TBNA)对于支气管纤维镜不可见的腔外纵隔和肺门病变的检出率,评价两种方法的命中率是否与每个个体病变的数目、大小和位置有关。方法本研究获得机构审查委员会的批准,并获得知情同意书。28例共50个于支气管纤维镜下不可见的纵隔和肺门病变[平均短轴直径(14±5)mm,范围:6～38mm]进行了TBNA。

关键词：支气管纤维镜肺门纵隔胸膜间间隙胸病变 CT

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肿瘤免疫治疗:进入最后冲刺

中国处方药 2008年第7期7卷 10-10页

作者： Louis m.weiner 海燕

肿瘤能够逃避或者攻击宿主的免疫反应,而在Hunder等人的研究中,通过给一例转移性黑色素瘤患者输入自体同源的CD4+T细胞克隆解决了肿瘤诱导的免疫抑制问题。

关键词：肿瘤免疫治疗转移性黑色素瘤免疫抑制问题 T细胞克隆 CD4^+ 免疫反应肿瘤诱导

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当心毛粪石的燃烧:简要报道和警告1例

世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 59-59页

作者： Ravalm.V. weiner T.m. 宁亮 Division of Pediatric Surgery Department of SurgeryUniv. of NCat Chapel Hill Chapel Hill NC 27599-7223 United States

Operating room fires are receiving increasing attention in the medical literat ure and in the general public. The best way to reduce these iatrogenic, sometime s devastating, events is communication and education. The authors present the ca se of a 14-year-old adolescent girl who had an apparent explosive event during a laparotomy for removal of a large gastric trichobezoar. This event was presum ably associated with gas production under increased pressures in the gastrointes tinal tract caused by an obstructive and decomposing trichobezoar. This is the f irst reported association between trichobezoars and potential intraoperative fir e and/or injury. It is the recommendation of the authors to avoid the use of ele ctrocautery when initially entering a portion of the gastrointestinal tract thou ght to contain a bezoar to avoid the potential for surgical fire or concussive t issue damage.

关键词：毛粪石肠道梗阻可燃性气体

Species traits and shoot-root biomass allocation in 20 dry-grassland species

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Journal of Plant Ecology 2018年第2期11卷 273-285页

作者： Iveta Husáková Jacob weiner Zuzana münzbergová Department of Botany Faculty of ScienceCharles UniversityBenátská2CZ-12801 PragueCzech Republic Institute of Botany Academy of Sciences of the Czech RepublicZámek 1CZ-25243 PrůhoniceCzech Republic Department of Plant and Environmental Sciences University of CopenhagenThorvaldsensvej 40DK-1871 FrederiksbergDenmark

Aims A plant has a limited amount of resources at any time and it allo-cates them to different *** spite of the large number of previous studies on allocation patterns within single species,knowledge of general patterns in species allocation is still very *** is because each study was done in different condi-tions using different methodology,making generalization *** investigate intraspecific above-versus below-ground biomass allocation among individuals across a spectrum of dry-grassland plant species at two different developmental stages and ask whether allocation is age-and species specific,and whether differences among species can be explained by their life-history traits and *** We collected data on above-and below-ground biomass of seedlings and adult plants of 20 species from a common garden *** analysed data on shoot-root biomass allocation allometrically and studied the relationship between the allometric exponents(slopes on log-log scale),species life-history traits and phylogenetic *** Findings We found isometric as well as allometric patterns of biomass alloca-tion in the studied *** and adult individuals of more than half of the species differed in their above-versus below-ground biomass allometric *** and adult individuals of the remaining species differed in their allometric coefficients(inter-cepts).Annual species generally allocated proportionally more to above-than below-ground biomass as seedlings than as adults,whereas perennial species showed the opposite *** life-history traits,such as plant life span,age of first flowering,month in which the species begin flowering and specific leaf area were much more important in explaining differences in shoot-root allometry among species than were phylogenetic *** suggests that allocation patterns vary greatly among closely related species but can be predicted based on species life-hi

关键词： above-ground biomass below-ground biomass allometry isometry seedling adult plant life-history traits phylogenetic relatedness root-shoot ratio

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预防医院耐药菌感染--2014年美国

上海预防医学 2017年第2期29卷 163-167页

作者： Lindsey m.weiner,mPH Scott K.Fridkin,mD Zuleika Aponte-Torres,mPH Lacey Avery,mA Nicole Coffin,mA margaret A.Dudeck,mPH Jonathan R.Edwards,mStat John A.Jernigan,mD Rebecca Konnor,mPH minn m.Soe,mBBS,mPH Kelly Peterson L.Clifford mcDonald,mD 刘洪霞(综述) 金克峙(审校) Division of Healthcare Quality Promotion National Center for Emerging and Zoonotic Infectious Diseases CDC. 不详

耐药菌是一种世界性的公共卫生威胁。2013年疾病预防控制中心（CDC）的一项报告概述了美国前18位危急和严重级别的耐药相关的威胁。

关键词：疾病预防控制中心耐药菌感染美国医院公共卫生