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Tungsten 2025年第1期7卷 32-49页

作者： Li-Rong Xiao Chen Chen Shuo Wang Zi-Yin Dai Hideo Kimura Cui Ni Chuan-Xin Hou xue-Qin Sun Si-Jie Guo Wei Du Xiu-Bo Xie School of Environmental and Material Engineering Yantai University Bosch HUAYU Steering Systems (Yantai) Co. Ltd.Ytp/MFE University of Tennessee Knoxville Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta Shandong University of Aeronautics

MgH2is considered as a promising hydrogen storage material for its high hydrogen storage capacity,low cost and abundant resource ***,the low kinetics and high enthalpy formation of MgH2limit its wide *** the perspective of adding catalysts to enhance the hydrogen storage properties of Mg-MgH2,this article elaborated the main catalysts based on Ti and Nb transition elements,including single oxide catalysts,binary oxides catalysts（combined with Ni,Na,Sr,V,etc.）,multiple catalysts bound to carbon,and composite catalysts with Ti and Nb elements combined with MXene ***,the main pathways of various catalysts to reduce the reaction activity and broaden the hydrogen desorption channel were also *** Ti-based catalysts can enhance the reactive sites of the matrix by forming multivalent states,while Nb-based catalysts broaden the hydrogen reaction channels by forming tiny *** improving the size structure and enhancing the grain size stability,combined with carbon materials should be the future considerations.

关键词： Catalysts Mg-based hydrogen storage alloys Solid hydrogen storage Transition metal elements

Upregulated IRF9 promotes cell apoptosis of hyperlipidemia acute pancreatitis with heart injury by regulating SIRT1

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BIOCELL 2021年第1期45卷 129-138页

作者： YUN SUN YI LIU BINHUA xue XIAODIE WANG weili YU Department of Intensive Care Unit The Second Affiliated Hospital of Anhui Medical UniversityHefei230601China

Hyperlipidemia acute pancreatitis(HLAP)is a significant cause of AP,characterized by recurrent attacks,more complications and high incidence and *** is often accompanied by single or multiple organ *** regulation of interferon-regulatory factor 9(IRF9)on sirtuin-1(SIRT1)contributes to a range of ***,the function of IRF9 and SIRT1,and the relationship of the two in HLAP with heart injury remain to be illustrated so *** models of HLAP were set up by feeding with high-fat chow and subsequently injecting 20%L-arginine *** degree of pancreas and heart tissue injury was *** cell apoptosis was assayed by the TUNEL ***9,SIRT1,p53 and acetylated p53(Ac-p53)expression levels were measured by qRT-PCR and western *** correlation between SIRT1 and IRF9 expression levels was *** showed that the damage degree in rat pancreas and heart tissues of AP and HLAP group was more distinctly and heart cell apoptosis was ***,heart injury and cell apoptosis of the HLAP group were more remarkable than that of the AP *** increases of IRF9 and Ac-p53/p53 expression and a marked drop of SIRT1 expression were observed in the AP and HLAP group rather than NC and HLNC ***9 and Ac-p53/p53 expression levels of the HLAP group were markedly raised compared with the AP ***1 expression of the HLAP group was obviously lower than that of the AP *** was an inverse correlation between the decrease of SIRT1 and the increase of IRF9 in AP and HLAP *** on the above findings,we drew a conclusion that in pancreatitis with heart injury,upregulated IRF9 inhibited SIRT1 expression,elevated the acetylation of p53,and increased myocardial cell *** further exacerbated pancreas and heart injury and accelerated myocardial cell *** results would furnish an experimental and theoretical basis to diagnose and therapy diseases.

关键词： IRF9 SIRT1 HLAP Cardiac injury Apoptosis

Enhanced subacute ischemic stroke treatment via multistage drug delivery system design for combination therapy

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Science China Chemistry 2025年

作者： Xihan Xu Juan-Juan Li Jiamin Li Hui-Yan Zhang Yilin Qi Bing-Sen Shi Tianqi Li Shan-Shan Su Weitao Zhao Chang Chen Zhongying Gong Huiyu Liu Ke-Rang Wang Dong-Sheng Guo xue xue State Key Laboratory of Medicinal Chemical Biology College of Pharmacy Nankai University College of Chemistry State Key Laboratory of Elemento-Organic Chemistry Key Laboratory of Functional Polymer Materials (Ministry of Education) Frontiers Science Center for New Organic Matter Collaborative Innovation Center of Chemical Science and EngineeringNankai University College of Chemistry and Materials Science State Key Laboratory of New Pharmaceutical Preparations and Excipients Key Laboratory of Medicinal Chemistry and Molecular Diagnosis (Ministry of Education) Key Laboratory of Chemical Biology of Hebei Province Hebei Research Center of the Basic Discipline of Synthetic Chemistry Hebei University Department of Neurology Tianjin First Central Hospital School of Medicine Nankai University Beijing Advanced Innovation Center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic Composites Beijing Laboratory of Biomedical Materials Bionanomaterials & Translational Engineering Laboratory Beijing Key Laboratory of BioprocessBeijing University of Chemical Technology

The management of acute ischemic stroke remains challenging due to its abrupt onset and the narrow treatment window,resulting in high rates of disability and *** therapy for neuroprotection and neurorepair strategies provided new hopes for subacute stroke *** we designed a multistage nanodelivery system that matches the unique microenvironment of the subacute phase of stroke,which utilizes calixarene as a building block to effectively load the neuroprotective drug *** calixarene is designed with glycosidic linkages targeting the glucose transporter 1 (GLUT1)on the blood-brain barrier (BBB) and azo bonds that are responsive to hypoxic ***,the decomposed calixarene molecules themselves possess intrinsic bio-activation to modulate inflammatory responses,achieving a multistage therapeutic approach that transitions from targeting to release and finally to *** approach combines anti-inflammation and neuroprotection,providing a multi-level treatment *** system was validated in a rat model of permanent middle cerebral artery occlusion (pMCAO),demonstrating that intravenous administration of the nanodelivery system repairs brain damage and improves motor function 24 h post-pMCAO *** work offers a precise and integrative strategy for stroke patients missing the acute therapy window to improve functional recovery and enhance the effect of comprehensive treatment.

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HPLC法测定肝素钠注射液中6种抑菌剂

药学研究 2022年第6期41卷 369-372页

作者：由鹏飞李春焕陈晓张迅杰薛维丽张乃斌山东省食品药品检验研究院国家药品监督管理局仿制药研究与评价重点实验室山东省仿制药一致性评价工程技术研究中心山东济南250101

目的建立高效液相色谱(HPLC)法同时测定肝素钠注射液中苯酚、苯甲醇、三氯叔丁醇、羟苯甲酯、羟苯乙酯、羟苯丙酯6种抑菌剂。方法采用Agilent Zorbax SB-C_(18)(4.6 mm×250 mm,5μm)色谱柱,流动相A为水,流动相B为甲醇,梯度洗脱,流速为1... 详细信息

目的建立高效液相色谱(HPLC)法同时测定肝素钠注射液中苯酚、苯甲醇、三氯叔丁醇、羟苯甲酯、羟苯乙酯、羟苯丙酯6种抑菌剂。方法采用Agilent Zorbax SB-C_(18)(4.6 mm×250 mm,5μm)色谱柱,流动相A为水,流动相B为甲醇,梯度洗脱,流速为1.0 mL·min^(-1),检测波长为220 nm及256 nm,柱温30℃。结果苯酚、苯甲醇、羟苯甲酯、羟苯乙酯、三氯叔丁醇、羟苯丙酯分别在25.00~400.06μg·mL^(-1)(r=1.0000)、104.49~1671.88μg·mL^(-1)(r=0.9999)、30.65~490.4μg·mL^(-1)(r=0.9999)、5.36~85.81μg·mL^(-1)(r=0.9999)、49.60~793.54μg·mL^(-1)(r=0.9999)、5.03~80.45μg·mL^(-1)(r=1.0000)内线性关系良好,平均回收率分别为100.3%、99.7%、99.8%、100.0%、99.4%和100.1%,RSD分别为1.0%、1.2%、1.3%、1.4%、1.4%和1.4%(n=9)。结论方法准确,重现性好,结果可靠,可用于肝素钠注射液中6种抑菌剂的测定。

关键词：高效液相色谱法肝素钠注射液抑菌剂苯酚苯甲醇羟苯甲酯羟苯乙酯三氯叔丁醇羟苯丙酯

Staged dendrite suppression for high safe and stable lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： Jun Jiang Zhenjie Lu Yanwen Ding Shujun Liu Zhijie Qi Tian Tang Yunfan Zhang Zhiyuan Ma Jingwen Sun Liang xue Wenyao Zhang Pan Xiong Xin Wang Junwu Zhu Yongsheng Fu Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Ductility

Mesospheric tide comparisons at low latitudes observed by two collocated meteor radars

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Earth and Planetary Physics 2025年第1期9卷 54-68页

作者： Jian Li Wen Yi XiangHui xue Jie Zeng HaiLun Ye JianYuan Wang JinSong Chen Na Li TingDi Chen Chinese Academy of Sciences(CAS)Key Laboratory of Geospace Environment Department of Geophysics and Planetary SciencesUniversity of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Comparative Planetology Anhui Mengcheng Geophysics National Observation and Research StationUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230026China Collaborative Innovation Center of Astronautical Science and Technology Harbin 150001China National Key Laboratory of Electromagnetic Environment China Research Institute of Radiowave PropagationQingdao 266107China Yunnan Kunming Electromagnetic Environment National Observation and Research Station Qujing Kunming 655000China

Accurate knowledge of mesospheric winds and waves is essential for studying the dynamics and climate in the mesosphere and lower thermosphere(MLT)*** this study,we conduct a comparative analysis of the mesosphere tidal results obtained from two adjacent meteor radars at low latitudes in Kunming,China,from November 2013 to December *** two radars operate at different frequencies of 37.5 MHz and 53.1 MHz,***,overall good agreement is observed between the two radars in terms of horizontal winds and tide *** results show that the dominant tidal waves of the zonal and meridional winds are diurnal and semidiurnal ***,we conduct an exhaustive statistical analysis to compare the tidal amplitudes and vertical wavelengths recorded by the dual radar systems,which reveals a high degree of alignment in tidal *** investigation includes variances and covariances of tidal amplitudes,which demonstrate remarkable consistency across measurements from both *** finding highlights clear uniformity in the mesospheric tidal patterns observed at low latitudes by the two neighboring meteor *** of the comparative analysis specifically underscore the significant correlation in vertical wavelength measurements,validating the robustness of radar observations for tidal research.

关键词： mesosphere and lower thermosphere region meteor radar mesospheric winds tides

Comparative analysis of empirical and deep learning models for ionospheric sporadic E layer prediction

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Earth and Planetary Physics 2025年第1期9卷 10-19页

作者： BingKun Yu PengHao Tian XiangHui xue Christopher JScott HaiLun Ye JianFei Wu Wen Yi TingDi Chen XianKang Dou Institute of Deep Space Sciences Deep Space Exploration LaboratoryHefei 230088China CAS Key Laboratory of Geospace Environment School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China Department of Meteorology University of ReadingReading RG66BBUK

Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 *** they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite *** this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde *** deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular.

关键词： ionospheric sporadic E layer radio occultation ionosondes numerical model deep learning model artificial intelligence

Investigation on the interaction of dispersed and elongated bubbles based on laser-induced fluorescence

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Optoelectronics Letters 2025年

作者： xue Ting SHI Ruini LIU Jinshun WANG Haixia WU Yan School of Electrical and Information Engineering， Tianjin University

The purpose of this paper is to investigate the interaction between dispersed and elongated bubbles in horizontal slug flow utilizing the laser-induced fluorescence method. A Segmentation method based on the fuzzy C-mean (FCM) algorithm is proposed to effectively separate elongated bubbles from the liquid phase， and an extreme value extraction method is developed to calculate the number of dispersed bubbles in front of the nose of elongated bubbles. Moreover， the velocity offsets of elongated bubbles with and without dispersed bubbles are calculated separately based on contour extraction. In addition， the effect of dispersed bubbles on the fluctuating offsets of the nose tip position and velocity of elongated bubbles are statistically investigated under different flow velocities. The experimental results show that the increase of the gas-liquid flow velocity exacerbates the radial deviation of the nose tip and the fluctuation of axial velocity.

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联合微信进行消化内科PBL教学的效果评估

科教文汇 2017年第3期 89-91页

作者：王深皓鲁晓岚王卫利薛芝琴赵刚程妍西安交通大学第二附属医院消化科陕西西安710004 西安交通大学第二附属医院内科学教研室陕西西安710004

目的:评价在消化内科学临床学习中联合微信进行以问题为基础的学习(PBL)教学的教学效果。方法:选取西安交通大学临床医学专业本科生及8年制学生共128名,在消化内科学PBL教学中联合微信进行教学,并进行问卷调查,了解医学生对联合微信的PB... 详细信息

目的:评价在消化内科学临床学习中联合微信进行以问题为基础的学习(PBL)教学的教学效果。方法:选取西安交通大学临床医学专业本科生及8年制学生共128名,在消化内科学PBL教学中联合微信进行教学,并进行问卷调查,了解医学生对联合微信的PBL教学的主观态度以及该教学方式实施前后对自身综合能力的评价。结果:86.7%学生对联合微信进行PBL教学持肯定态度。与一般的PBL教学相比,医学生认为联合微信进行PBL教学有助于提高自身综合能力,尤其是在提高自我学习能力、查找资料和信息分析能力等方面收获更多,差异具有统计学意义。结论:联合微信进行消化内科PBL教学总体效果较好,有助于提高医学生多方面学习能力。

关键词： PBL教学微信消化内科学

Preparation and Luminescence Properties of Color-tunable Single-phased LaPO4：Eu3＋/Tb3＋ Phosphors

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Chemical Research in Chinese Universities 2016年第2期32卷 248-252页

作者： DONG weili ZHANG Xiyan SHI Hui WANG Nengli ZHANG Wenmin LI Liang xue Qingxue School of Materials Science and Engineering Changchun University of Science and Technology Changchun 130022 P. R. China

A novel series of color-tunable single-phased phosphors La1-x-yPO4：xEu3＋/yTb3＋（x=0, 0.01, 0.02, 0.03, 0.04, 0.05; y=0, 0.05, 0.10, 0.15, 0.20） was synthesized via microwave-assisted co-precipitation method with diammonium hydrogen phosphate as precipitant. The morphology, crystal structure and photoluminescence properties of the as-prepared samples were characterized by means of X-ray diffraction（XRD）, scanning electron microscopy（SEM） and fluorescence spectrophotometer. The results reveal that the as-synthesized samples calcined at 1100 ℃ display spherical morphology with uniform distribution. Upon excitation with 350 nm ultraviolet radiation, the LaPOa：Eu3＋/Tb3＋ phosphors showed a green light peaking at 543 nm assigned to the characteristic 5Da-7F5 emission of Tb3＋ and a red light peaking at 591 nm corresponding to the characteristic 5D0-7F1 emission of Eu3＋ simultaneously. For the Eu3＋/Tb3＋ co-activated phosphors, Tb3＋ acts as an efficient sensitizer to enhance the emission intensity of Eu3＋ ions. The energy transfer mechanism and the emission color tunability of LaPO4：Eu3＋/Tb3＋ have been studied. The results indicate that a color-tunable luminescence（from green to white to red） can be achieved by adjusting the Eu3＋/Tb3＋ doping ratio in the LaPO4 host matrix.

关键词： Lanthanum phosphate phosphor Photoluminescence property Color-tunable