检索结果-南通市图书馆

Asian Journal of Urology 2023年第1期10卷 50-57页

作者： Hua Gong Kang chen Lan Zhou Yongchao Jin Weihua Chen Department of Urology Zhoupu HospitalMedicine and Health SciencesShanghai UniversityShanghaiChina Department of Urology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Objective:Deleted in liver cancer 1(DLC1)is a GTPase-activating protein that is reported as a suppressor in certain human cancers.However,the detailed biological function of DLC1 is still unclear in human prostate cancer(PCa).In the present study,we aimed to explore the function of DLC1 in PCa cells.Methods:Silencing and overexpression of DLC1 were induced in an androgen-sensitive PCa cell line(LNCaP)using RNA interference and lentiviral vector transduction.The Cell Counting Kit-8 assay was performed to determine cell proliferation.The cell cycle was examined by performing a propidium iodide staining assay.Results:Our results indicated that DLC1 overexpression markedly suppressed the proliferation and cell cycle progression of LNCaP cells.Moreover,DLC1 expression was negatively correlated with Rho-associated protein kinase(ROCK)expression in LNCaP cells.Importantly,this study showed that the ROCK inhibitor Y27632 restored the function of DLC1 in LNCaP cells and reduced the tumorigenicity of LNCaP cells in vivo.Conclusion:Our results indicated that DLC1 overexpression markedly suppressed the proliferation and cell cycle progression of PCa cells and negatively correlated with ROCK expression in PCa cells and tissue.

关键词： Cell cycle Deleted in liver cancer 1 Proliferation Prostate cancer Rho-associated protein kinase

Research on Magnetically Coupled Resonant Detection Method for Breakpoint of Four Mesh Grounding Grid

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CES Transactions on Electrical Machines and Systems 2023年第2期7卷 218-228页

作者： Weihua Chen Shuai Wang Xiaoheng Yan Zhiquan Ye the School of Liaoning Technical University(Huludao) Liaoning Huludao125100China

Magnetically coupled resonant technology is a novel method for solving the breakpoint locating of power grounding grid.But the method can only detect breakpoints of a single mesh grounding grid at present.In this paper,a magnetically coupled resonant detection method for four-hole grounding grid breakpoint is proposed.Firstly,the equivalent circuit model of the four mesh grounding grid with two types of breakpoints,namely edge branch and intermediate branch,is established.The input impedance and phase angle of the system are obtained by analyzing the equivalent capacitance and equivalent resistance in the model.Secondly,the magnetically coupled resonant physical process of grounding grid faults is solved via HFSS software.The magnetic field intensity and phase frequency characteristic curves of four mesh holes with different branches and positions of breakpoints and different corrosion degrees are studied,and an experimental system is built to verify the feasibility.The results show that under the condition of grounding grid buried depth of 0.5 m and input frequency of 1~15MHz,and there is an inverse relationship between equivalent capacitance and distortion frequency,the phase angle is positively correlated with the degree of corrosion of grounding grid,and the error of signal distortion frequency can be positioned at 5%.This paper provides some ideas for the application of magnetic coupling grounding grid detection technology.

关键词： Grounding grid Magnetically coupled resonant detection Input impedance Phase frequency characteristic curve

Hybrid intelligent modeling approach for online predicting and simulating surface temperature of HVs

在线全文

学校读者我要写书评

暂无评论

International Journal of Modeling, Simulation, and Scientific Computing 2022年第2期13卷 111-124页

作者： Ming Tie Hong Fang Jianlin Wang Weihua Chen Science and Technology on Space Physics Laboratory Beijing 100076P.R.China

Online prediction as well as online simulation of surface temperature will play a sig-nificant role in flight safety of future near space hypersonic vehicles(HVs).But it still remains a classical scientific problem both in thermodynamics and aerospace sci-ence.In view of the complex HV structure and complex heat conduction procedure,three-dimensional numerical simulation is too inefficient for online prediction,while cur-rent rapid computation methods cannot meet the requirement of accuracy.Therefore,a hybrid intelligent dynamic modeling approach is proposed to estimate the surface temperature of HV with the combination of mechanism equations,test data and intel-ligent modeling technology.A simplified model based on a mechanism equation and experimental formulas is presented for predicting or simulating transient heat conduc-tion procedure efficiently,while a case-based reasoning(CBR)algorithm is developed to estimate two uncertain coefficients in the simplified model.Furthermore,a support vector regression(SVR)-based model is developed to compensate the modeling error.With the data both from high-precision finite element computation and from real-world HV thermal protection experiments,a number of comparative simulations demonstrate the effectiveness of the proposed hybrid intelligent modeling approach.

关键词： Hypersonic vehicles transient heat conduction hybrid intelligent support vector regression case-based reasoning

Green synthesis of novel conjugated poly(perylene diimide)as cathode with stable sodium storage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第7期16卷 9538-9545页

作者： Jinyun Zheng Xinxin Liu Wenbin Li Wenjie Li Xiangming Feng Weihua Chen College of Chemistry&Green Catalysis Center Zhengzhou UniversityZhengzhou 450001China

Conjugated polymers of organic carbonyl compounds are promising electrode materials for energy storage devices owing to the renewable development prospects,structural variability,and better insolubility in electrolyte.However,the synthesis methods in solution are cumbersome and complicated in separation and purification,and require the introduction of functional groups and use of expensive catalysts.In this work,a novel conjugated poly(3,4,9,10-perylenetetracarboxylic diimide)(PPI)with superior thermal stability and lower solubility was prepared successfully by a green facile mechanical ball milling strategy.The PPI exhibits enhanced electrochemical dynamics performance,preferable rate capability,higher discharge capacity,and excellent cycling stability of 450 cycles at 0.2 C with higher capacity retention of 85.7%when used as cathode material for sodium-ion battery.Furthermore,the in-situ X-ray diffraction(XRD)and in-situ Raman investigations combined with the Fourier transform infrared(FT-IR)and X-ray photoelectron spectroscopy(XPS)were carried out to investigate the sodium storage mechanism.The results indicate that only two sodium ions are bound to two opposite carbonyl groups of PPI monomer to form sodium enolates during normal charging and discharging and to deliver available reversible capacity.

关键词： sodium-ion battery organic cathode carbonyl compound stability green synthesis

High loading FeS2 nanoparticles anchored on biomass-derived carbon tube as low cost and long cycle anode for sodium-ion batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green Energy & Environment 2020年第1期5卷 50-58页

作者： Kongyao chen Gaojie Li Yanjie Wang Weihua Chen Liwei Mi Center for Advanced Materials Research Zhongyuan University of TechnologyHenan450007China College of Chemistry and Molecular Engineering Zhengzhou UniversityHenan450001China

In recent years, the sodium storage mechanism and performance optimization of FeS2 have been studied intensively. However, before the commercial application of FeS2, preconditions of low-cost, simple craft and scale production of nanoscale FeS2 are also essential. Based on above challenges, mesh-like FeS2/carbon tube/FeS2 composites are prepared simply from green, low-cost and renewable natural herb in this work. With the assistance of protogenetic interconnected carbon tube network(only 5.3 wt%), FeS2/carbon tube/FeS2 composites show high capacity(542.2 mA h g^-1), good stability(< 0.005% per cycle over 1000 cycles), and excellent rate performance(426.2 mA h g^-1 at 2 A g^-1).The outstanding electrochemical performance of FeS2/carbon tube/FeS2 composites may be attributed to the unique interconnected reticular structure, meaning that FeS2 nanoparticles are effectively immobilized by carbon tube network via physical encapsulation and chemical bonding.More importantly, this work may provide green and low cost preparation method for specially structured metal sulfides/carbon composites,which promotes their commercial utilization in environmentally friendly energy storage system.

关键词： FeS2 Biomass-drived carbon Mesh-like structure Low cost Sodium-ion batteries

Tailored ZnF_(2)/ZnS-rich interphase for reversible aqueous Zn batteries

在线全文

学校读者我要写书评

暂无评论

Nano Research 2023年第4期16卷 4996-5005页

作者： Junmin Ge Yaoyang Zhang Zhengkun Xie Huabin Xie Weihua Chen Bingan Lu College of Chemistry&Green Catalysis Center Zhengzhou UniversityZhengzhou 450001China School of Physics and Electronics Hunan UniversityChangsha 410082China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin 300071China

The urgent need for highly safe and sustainable large-scale energy storage systems for residential buildings has led to research into aqueous zinc ion batteries.However,when zinc is used in aqueous zinc ion batteries,it suffers from severe irreversibility due to its low Coulombic efficiency,dendrite growth,and side reactions.To address these challenges,we take advantage of organic cation to induce trifluoromethanesulfonate decomposition to build zinc fluoride/zinc sulfide-rich solid electrolyte interphase(SEI)that not only can adapt to a high areal capacity of deposition/stripping disturbance but also adjust zinc ion deposition path to eliminate dendrite.As a result,the unique interface can promote the Zn battery to achieve excellent electrochemical performance:high levels of plating/stripping Coulombic efficiency(99.8%),stability life(6,600 h),and cumulative capacity(66,000 mAh·cm^(−2))at 68%zinc utilization(20 mAh·cm^(−2)).More importantly,the SEI significantly enhances the cyclability of full battery under limited Zn,lean electrolyte,and high areal capacity cathode conditions.

关键词： aqueous zinc batteries ZnF_(2)/ZnS-rich interphase reversibility metal anode utilization interfacial chemistry

Synthesis of carbon nanotubes-supported porous silicon microparticles in low-temperature molten salt for highperformance Li-ion battery anodes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第7期15卷 6184-6191页

作者： Qianliang Zhang Baojuan Xi Weihua Chen Jinkui Feng Yitai Qian Shenglin Xiong Key Laboratory of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringState Key Laboratory of Crystal MaterialsShandong UniversityJinan 250100China Key Laboratory of Material Processing and Mold of Ministry of Education Zhengzhou UniversityZhengzhou 450001China Key Laboratory for Liquid-Solid Structural Evolution&Processing of Materials Ministry of EducationSchool of Materials Science and EngineeringShandong UniversityJinan 250061China

Silicon-based materials has attracted attention as a promising candidate for lithium-ion batteries(LIBs)with high energy density.However,severe volume variation,pulverization,and poor conductivity hindered the development of Si based materials.In this study,porous Si microparticles supported by carbon nanotubes(p-Si/CNT)are fabricated through simple molten salt assisted dealloying process at low temperature followed by acid treatment.The ZnCl2 molten salt not only provides the liquid environment to enhance the reaction,but also participates the dealloying process and works as template for porous structure when removes by acid treatment.Additionally,distribution of defect sites in CNTs also increases after molten salt process.Density function theory(DFT)calculations further prove the defects could improve the adsorption of Li+.The participation of CNTs can also contribute to the reaction kinetics and retain the integrity of the electrode.As expected,the p-Si/CNT anode manifests enhanced lithium-storage performance in terms of superior cycling stability and good rate capability.The p-Si/CNT//LiCoO_(2) full cell assembly further demonstrates its potential as a prospective anode for high-performance LIBs.

关键词： porous Si microparticles carbon nanotubes molten salt lithium-ion batteries

Seasonal variation of transport pathways and potential source areas at high inorganic nitrogen wet deposition sites in southern China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2022年第4期34卷 444-453页

作者： Shuidi He Minjuan Huang Lianming Zheng Ming Chang Weihua Chen Qianqian Xie Xuemei Wang Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Institute for Environmental and Climate ResearchJinan UniversityGuangzhou 510632China School of Atmospheric Sciences Guangdong Province Key Laboratory for Climate Change and Natural Disaster StudiesSun Yat-sen UniversityZhuhai 519082China Southern Marine Science and Engineering Guangdong Laboratory Zhuhai 519082China

This study attempts to identify the dominant transport pathways,potential source areas,and their seasonal variation at sites with high inorganic nitrogen(IN)wet deposition flux in southern China.This is a long-term study(2010-2017)based on continuous deposition measurements at the Guangzhou urban site(GZ)and the Dinghushan Natural Reserve site(DHS)located in the Pearl River Delta(PRD)region.A dataset on monthly IN concentration in precipitation and wet deposition flux were provided.The average annual fluxes measured at both sites(GZ:33.04±9.52,DHS:20.52±10.22 kg N/(ha·year))were higher,while the ratios of reduced to oxidized N(GZ:1.19±0.77,DHS:1.25±0.84)were lower compared with the national mean level and the previous reported level throughout the PRD region.The dominant pathways were not always consistent with the highest proportional trajectory clusters.The transport pathways contributing most of deposition were identified in the north and northnortheast in the dry season and in the east-southeast,east,and south-southwest in the wet season.A weighted potential source contribution function(WPSCF)value>0.3 was determined reasonably to define the potential source area.Emission within the PRD region contributed the majority(≥95%at both sites)of the IN deposition in the wet season,while the contribution outside the region increased significantly in the dry season(GZ:27.86%,DHS:95.26%).Our results could help create more effective policy to control precursor emissions for IN fluxes,enabling reduction of the ecological risks due to excessive nitrogen.

关键词： Inorganic nitrogen(IN) Wet deposition Seasonal variation Transport pathways Potential source areas Emission sectors

A Spectral Segmentation Method for Large Meshes

在线全文

学校读者我要写书评

暂无评论

Communications in Mathematics and Statistics 2023年第3期11卷 583-607页

作者： Xiaohan Bao weihua Tong Falai chen School of Mathematical Sciences University of Science and Technology of ChinaHefei230026AnhuiPeople’s Republic of China

Mesh segmentation is a fundamental and critical task in mesh processing,and it has been studied extensively in computer graphics and geometric modeling communities.However,current methods are not well suited for segmenting large meshes which are now common in many applications.This paper proposes a new spectral segmentation method specifically designed for large meshes inspired by multi-resolution representations.Building on edge collapse operators and progressive mesh representations,we first devise a feature-aware simplification algorithm that can generate a coarse mesh which keeps the same topology as the input mesh and preserves as many features of the input mesh as possible.Then,using the spectral segmentation method proposed in Tong et al.(IEEE Trans Vis Comput Graph 26(4):1807–1820,2020),we perform partition on the coarse mesh to obtain a coarse segmentation which mimics closely the desired segmentation of the input mesh.By reversing the simplification process through vertex split operators,we present a fast algorithm which maps the coarse segmentation to the input mesh and therefore obtain an initial segmentation of the input mesh.Finally,to smooth some jaggy boundaries between adjacent parts of the initial segmentation or align with the desired boundaries,we propose an efficient method to evolve those boundaries driven by geodesic curvature flows.As demonstrated by experimental results on a variety of large meshes,our method outperforms the state-of-the-art segmentation method in terms of not only speed but also usability.

关键词： Mesh segmentation Spectral method Progressive mesh Feature-aware simplification Geodesic curvature flow

Numerical Analysis on Solidification Behavior of Graphene Nanoplatelet Based Nanofluid in Cold Storage Cavity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2022年第4期31卷 1180-1193页

作者： chen chen FENG Shiyu PENG Hao PENG Xiaotian LIU weihua College ofAerospace Engineering Nanjing University ofAeronautics and Astronautics Nanjing 210016China Institute of Thermal Engineering Shanghai Maritime UniversityShanghai 201306China

Addition of graphene nanoplatelet(GNP)into water is a promising method for improving cold storage system performance,and its application requires comprehensive understanding of solidification behavior of GNP-water nanofluid.In the present study,the influences of GNP mass concentration,cold storage cavity size and shape on solid-liquid interface evolution,temperature distribution,streamline profile as well as solidification rate are numerically analyzed.The enthalpy-porosity technique is adopted to track solid-liquid interface.The results show that the enhancement effect of GNPs on solidification is mainly reflected in the final stage in which heat conduction is predominant;the solidification occurs at the bottom of cavity in the early stage,and the solid-liquid interface is similar to the shape of cavity itself and then tends to be circular in the middle and final stages respectively;the reduction degree of solidification time reaches 30.1%at GNP mass concentration of 1.2 wt%under present simulation conditions;decreasing cavity size and adopting triangular cavity are beneficial for promoting the solidification,but they will suppress the enhancement effect of GNPs on solidification.

关键词： cavity shape graphene nanofluid phase change material solidification