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Defence Technology（防务技术） 2024年第1期31卷 230-241页

作者： Junbao Li weibing Li Xiaoming wang ZNDY of Ministerial Key Laboratory Nanjing University of Science and TechnologyNanjing 210094China

This study proposed three types of Al—Hf reactive materials with particle size ratios(a),which were almost completely dense(porosity of<5.40%)owing to their preparation using hot-pressing technology.Microstructure characteristics and phase composition were analyzed,and the influence of particle size ratios on dynamic mechanical behavior and damage mechanism were investigated.The prepared sample with a=0.1 exhibited continuous wrapping of the Hf phase by the Al phase.Hf—Hf contact(continuous Hf phase)within the sample gradually increased with increasing a,and a small amount of fine Hf appeared for the sample with a=1.The reactive materials exhibited clear strain-rate sensitivity,with flow stressσ0.05and failure strainεfincreasing approximately linearly with increasing strain rate.ε.It is found that the plastic deformation of the material increased with increasing strain rate.As a increased from 0.1 to 1,the flow stress gradually increased.Impact failure of the material was dominated by ductile fracture with a large Al phase plastic deformation band for lower a,while brittle fracture with crushed Hf particles occurred at higher a.Finally,a constitutive model based on BP neural network was proposed to describe the stress-strain relationships of the materials,with an average relative error of 2.22%.

关键词： Reactive material Particle size Split Hopkinson pressure bar test Stressestrain relationship Impact failure BP neural network

Chinese expert consensus statement on the diagnosis and treatment of Hirschsprung disease

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Chinese Medical Journal 2024年第5期137卷 505-507页

作者： Tianqi Zhu weibing Tang Jiexiong Feng the Chinese Research Group of Hirschsprung Disease Department of Pediatric Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyHubei Clinical Center of Hirschsprung’s Disease and Allied DisordersWuhanHubei 430030China Department of Neonatal Surgery Children’s Hospital of Nanjing Medical UniversityNanjingJiangsu 210008China 不详

Hirschsprung disease(HSCR)is a congenital anomaly of the intestine caused by the developmental absence of the enteric nervous system,which results in variable lengths of intestinal dysfunction and requires surgical intervention.^([1])Due to the complex etiology,multiple surgical procedures and postoperative complications,the diagnosis and treatment strategies of HSCR have always been the focus of pediatric surgeons around the world.Seventy pediatric surgical experts with rich clinical experience from almost all national and provincial children’s medical centers in China constituted the Chinese Research Group of Hirschsprung disease(CRGHSCR).

关键词： diagnosis intestine treatment

Transcriptomic and metabolomic analysis provides insights into lignin biosynthesis and accumulation and differences in lodging resistance in hybrid wheat

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Journal of Integrative Agriculture 2024年第4期23卷 1105-1117页

作者： weibing Yang Shengquan Zhang Qiling Hou Jiangang Gao Hanxia wang Xianchao Chen Xiangzheng Liao Fengting Zhang Changping Zhao Zhilie Qin Institute of Hybrid Wheat Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China Beijing Municipal Key Laboratory of Molecular Genetics of Hybrid Wheat Beijing 100097China

The use of hybrid wheat is one way to improve the yield in the future.However,greater plant heights increase lodging risk to some extent.In this study,two hybrid combinations with differences in lodging resistance were used to analyze the stem-related traits during the filling stage,and to investigate the mechanism of the difference in lodging resistance by analyzing lignin synthesis of the basal second internode(BSI).The stem-related traits such as the breaking strength,stem pole substantial degree(SPSD),and rind penetration strength(RPS),as well as the lignin content of the lodging-resistant combination(LRC),were significantly higher than those of the lodgingsensitive combination(LSC).The phenylpropanoid biosynthesis pathway was significantly and simultaneously enriched according to the transcriptomics and metabolomics analysis at the later filling stage.A total of 35 critical regulatory genes involved in the phenylpropanoid pathway were identified.Moreover,42%of the identified genes were significantly and differentially expressed at the later grain-filling stage between the two combinations,among which more than 80%were strongly up-regulated at that stage in the LRC compared with LSC.On the contrary,the LRC displayed lower contents of lignin intermediate metabolites than the LSC.These results suggested that the key to the lodging resistance formation of LRC is largely the higher lignin synthesis at the later grain-filling stage.Finally,breeding strategies for synergistically improving plant height and lodging resistance of hybrid wheat were put forward by comparing the LRC with the conventional wheat applied in large areas.

关键词： gene expression lignin synthesis lodging-resistance hybrid wheat

Automatic detection and assessment of crack development in ultra-high performance concrete in the spatial and Fourier domains

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Frontiers of Structural and Civil Engineering 2024年第3期18卷 350-364页

作者： Jixing CAO Yao ZHANG Haijie HE weibing PENG Weigang ZHAO Zhiguo YAN Hehua ZHU School of Safety Engineering and Emergency Management Shijiazhuang Tiedao UniversityShijiazhuang 050043China College of Civil Engineering and Architecture Zhejiang UniversityHangzhou 310058China College of Civil and Architectural Engineering Taizhou UniversityTaizhou 318000China College of Civil Engineering and Architecture Zhejiang University of TechnologyHangzhou 310014China Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

Automatic detection and assessment of surface cracks are beneficial for understanding the mechanical performance of ultra-high performance concrete(UHPC).This study detects crack evolution using a novel dynamic mode decomposition(DMD)method.In this method,the sparse matrix‘determined’from images is used to reconstruct the foreground that contains cracks,and the global threshold method is adopted to extract the crack patterns.The application of the DMD method to the three-point bending test demonstrates the efficiency in inspecting cracks with high accuracy.Accordingly,the geometric features,including the area and its projection in two major directions,are evaluated over time.The relationship between the geometric properties of cracks and load-displacement curves of UHPC is discussed.Due to the irregular shape of cracks in the spatial domain,the cracks are then transformed into the Fourier domain to assess their development.Results indicate that crack patterns in the Fourier domain exhibit a distinct concentration around a central position.Moreover,the power spectral density of cracks exhibits an increasing trend over time.The investigation into crack evolution in both the spatial and Fourier domains contributes significantly to elucidating the mechanical behavior of UHPC.

关键词： dynamic mode decomposition ultra-high performance concrete crack detection geometric features Fourier domain

Plant regeneration in the new era:from molecular mechanisms to biotechnology applications

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Science China(Life Sciences) 2024年第7期67卷 1338-1367页

作者： Chunli Chen Yuxin Hu Momoko Ikeuchi Yuling Jiao Kalika Prasad Ying Hua Su Jun Xiao Lin Xu weibing Yang Zhong Zhao Wenkun Zhou Yun Zhou Jian Gao Jia-Wei wang National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China College of Life Science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of Sciences(CAS)China National Botanical GardenBeijing 100093China Division of Biological Sciences Graduate School of Science and TechnologyNara Institute of Science and TechnologyNara 630-0192Japan State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Center for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Indian Institute of Science Education and Research Pune 411008IndiaThiruvananthapuram 695551India State Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Sino-German Joint Research Center on Agricultural Biology Shandong Agricultural UniversityTai’an 271018China Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology(IGDB)CASBeijing 100101China CAS-JIC Centre of Excellence for Plant and Microbial Science(CEPAMS) IGDBCASBeijing 100101China National Key Laboratory of Plant Molecular Genetics CEMPSInstitute of Plant Physiology and Ecology(SIPPE)CASShanghai 200032China CEPAMS SIPPECASShanghai 200032China Hefei National Laboratory for Physical Sciences at the Microscale CEMPSSchool of Life SciencesDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Plant Environmental Resilience College of Biological SciencesChina Agricultural UniversityBeijing 100193China Department of Botany and Plant Pathology and Center for Plant Biology Purdue UniversityWest Lafayette 47907USA School of Life Science and Technology Shang

Plants or tissues can be regenerated through various pathways.Like animal regeneration,cell totipotency and pluripotency are the molecular basis of plant regeneration.Detailed systematic studies on Arabidopsis thaliana gradually unravel the fundamental mechanisms and principles underlying plant regeneration.Specifically,plant hormones,cell division,epigenetic remodeling,and transcription factors play crucial roles in reprogramming somatic cells and reestablishing meristematic cells.Recent research on basal non-vascular plants and monocot crops has revealed that plant regeneration differs among species,with various plant species using distinct mechanisms and displaying significant differences in regenerative capacity.Conducting multi-omics studies at the single-cell level,tracking plant regeneration processes in real-time,and deciphering the natural variation in regenerative capacity will ultimately help understand the essence of plant regeneration,improve crop regeneration efficiency,and contribute to future crop design.

关键词： apical meristem model species regeneration phytohormone plant cell reprogramming somatic embryogenesis

Monkeypox virus 2022,gene heterogeneity and protein polymorphism

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3576-3579页

作者： Yanjiao Li Jingjing Hou Zhong Sun Jingjing Hu Karuppiah Thilakavathy Yuxi wang Zhongjun Shao Yihan Lu weibing wang Chenglong Xiong Department of Epidemiology School of Public HealthFudan UniversityKey Laboratory of Public Health SafetyMinistry of Education200032 ShanghaiChina Department of Pulmonary and Critical Care Medicine Tongji HospitalSchool of MedicineTongji University200065 ShanghaiChina Department of Biomedical Sciences Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400Malaysia Department of Epidemiology Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational EnvironmentSchool of Public HealthAir Force Medical University710068 Xi’anChina

Dear Editor,Human monkeypox(MPX),an endemic disease in equatorial Africa,1 has been causing outbreaks in non-endemic countries since early May 2022.Interestingly,many confirmed cases have no history of travel to Africa.This is the first time many MPX cases have been reported concurrently in both non-endemic and endemic countries in disparate geographical areas.2 In response,we have analyzed 27 genes or sequences from 643 full-length human monkeypox virus(MPXV)genomes collected after January 1 and submitted by August 7,2022(Supplementary Table 1).We divided these 643 genomes into 24 clusters with a 95%identity threshold(Supplementary Table 2).

关键词： cases travel endemic

Patterns of human social contact and mask wearing in high-risk groups in China

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Infectious Diseases of Poverty 2022年第3期11卷 98-98页

作者： Bo Zheng Wenlong Zhu Jinhua Pan weibing wang 不详 Shanghai Institute of Infectious Disease and Biosecurity School of Public HealthFudan University138 Yi Xue Yuan RoadShanghai200032China

Background:The pandemic of coronavirus disease 2019(COVID-19)has changed human behavior in areas such as contact patterns and mask-wearing frequency.Exploring human–human contact patterns and mask-wearing habits in high-risk groups is an essential step in fully understanding the transmission of respiratory infection-based diseases.This study had aims to quantify local human–human(H–H)contacts in high-risk groups in representative provinces of China and to explore the occupation-specific assortativity and heterogeneity of social contacts.Methods:Delivery workers,medical workers,preschoolers,and students from Qinghai,Shanghai,and Zhejiang were recruited to complete an online questionnaire that queried general information,logged contacts,and assessed the willingness to wear a mask in different settings.The“group contact”was defined as contact with a group at least 20 individuals.The numbers of contacts across different characteristics were assessed and age-specific contact matrices were established.A generalized additive mixed model was used to analyze the associations between the number of individual contacts and several characteristics.The factors influencing the frequency of mask wearing were evaluated with a logistic regression model.Results:A total of 611,287 contacts were reported by 15,635 participants.The frequency of daily individual contacts averaged 3.14(95%confidence interval:3.13–3.15)people per day,while that of group contacts was 37.90(95%CI:37.20–38.70).Skin-to-skin contact and long-duration contact were more likely to occur at home or among family members.Contact matrices of students were the most assortative(all contacts q-index=0.899,95%CI:0.894–0.904).Participants with larger household sizes reported having more contacts.Higher household income per capita was significantly associated with a greater number of contacts among preschoolers(P_(50,000–99,999)=0.033)and students(P_(10,000–29,999)=0.017).In each of the public places,the frequency of mask wearing was highest for delivery workers.For presc

关键词： COVID-19 Human-human contact pattern High-risk populatio

中老年人体力活动轨迹与工具性生活自理能力的关联性分析

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首都体育学院学报 2024年第2期36卷 207-216,226页

作者：卢婧雯王伟炳复旦大学体育教学部上海200032 复旦大学上海医学院上海200032

目的:探讨中老年人体力活动轨迹与其工具性日常生活自理能力(instrumental activities of daily living,IADL)的关系。方法:基于2011—2018年中国健康与养老追踪调查(the China health and retirement longitudinal study,CHARLS)的全国代表性大规模追踪数据,采用组基轨迹模型识别调查对象随访期间体力活动随时间变化的潜在分组和轨迹特征;采用多因素logistic回归模型分析不同体力活动轨迹类型与IADL失能的关联性。结果:调查对象体力活动轨迹被分为持续低体力活动组(2703人,占66.89%)、体力活动降低组(641人,占15.86%)、体力活动增加组(375人,占9.28%)及持续高体力活动组(322人,占7.97%),4组间IADL失能发生率比较,差异具有统计学意义(χ2=19.46,p<0.001)。多因素logistic回归模型显示,与持续低体力活动组比较,体力活动增加组和持续高体力活动组发生IADL失能的风险降低,对应的比值比(95%可信区间)分别为0.73(0.55,0.97)和0.59(0.42,0.83)。按性别、年龄、居住地和慢性病进行亚组分析结果显示,男女持续高体力活动组发生IADL失能的风险明显降低,而这种显著的关联性仅出现在60岁及以上老年人、居住在农村者和无慢性病者中。结论:不同类型体力活动轨迹与日常生活自理能力相关,持续高体力活动与体力活动增加轨迹会降低工具性日常生活自理能力失能的风险。

关键词：体力活动组基轨迹工具性日常生活自理能力

Impact of the national hepatitis B immunization program in China:a modeling study

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Infectious Diseases of Poverty 2022年第5期11卷 99-100页

作者： Zhixi Liu Mengying Li David W.Hutton Abram L.Wagner Ye Yao Wenlong Zhu Lingsheng Cao Shenglan Tang Jinhua Pan Yesheng wang Qi Zhao Hong Ren Ying wang weibing wang School of Public Health Shanghai Institute of Infectious Disease and BiosecurityFudan UniversityShanghaiChina Department of Social Medicine School of Public HealthFudan UniversityShanghaiChina 不详

Background:Elimination of hepatitis B virus(HBV)is a striking challenge for countries with high or moderate disease burden.Therefore,using China as a practical case to share experiences for similar countries may accelerate the achievement of the WHO 2030 target of 90%reduction in HBV-related incidence.We aim to evaluate the impact of national HBV immunization strategies in China;and the feasibility to achieve WHO 2030 targets under diferent scenarios.Methods:We constructed an expanded Susceptible-Exposed-Infectious-Recovered(SEIR)model and decision treeMarkov model to estimate the epidemic of HBV in China,assess the feasibility of 2030 Elimination Goals through the projections and conduct the economic analysis.Least square method was used to calibrate the expanded SEIR model by yearly data of laboratory-confrmed HBV cases from 1990 to 2018.Two models were separately used to evaluate the impact and cost-efectiveness of HBV vaccine by comparing prevalence of chronic HBV infections,qualityadjusted life-years(QALYs),incremental cost efectiveness ratio and beneft–cost ratio(BCR)under various intervention options,providing a basis for exploring new containment strategies.Results:Between 1990 and 2020,the number of chronic HBV infections decreased by 33.9%.The current status quo would lead to 55.73 million infections(3.95%prevalence)in 2030,compared to 90.63 million(6.42%prevalence)of the“Without the NIP”scenario(NIP:National Immunization Program),114.78 million(8.13%prevalence)without any interventions.The prevention of mother to child transmission(PMTCT)strategy showed a net beneft as 12,283.50 dollars per person,with BCR as 12.66,which is higher than that of universal vaccination at 9.49.Compared with no screening and no vaccination,the PMTCT strategy could save 7726.03 dollars for each QALY increase.Conclusions:Our fndings proved the HBV vaccination has demonstrated a substantial positive impact on controlling the epidemic of HBV in terms of efectiveness and economy after about 30 years of implementation of the nati

关键词： Hepatitis B National immunization program Prevalence Economic analysis Susceptible-ExposedInfectious-Recovered modeling

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双分支多维注意特征融合的高光谱图像分类

计算机工程与应用 2024年第7期60卷 192-203页

作者：马亚美王双亭都伟冰河南理工大学测绘与国土信息工程学院河南焦作454003

为改善高光谱图像小样本类别的分类性能,提高模型特征表达的稳健性,提出了双分支多维注意力特征融合的神经网络分类模型(DBMD)。DBMD采用两个分支分别进行光谱特征提取和混合特征提取。光谱分支通过密集连接的扩张卷积逐级提取特征,然... 详细信息

为改善高光谱图像小样本类别的分类性能,提高模型特征表达的稳健性,提出了双分支多维注意力特征融合的神经网络分类模型(DBMD)。DBMD采用两个分支分别进行光谱特征提取和混合特征提取。光谱分支通过密集连接的扩张卷积逐级提取特征,然后融合低、中、高级语义信息作为特征输出。混合分支采用3D-2D网络架构,并通过改进的Inception块提取空间尺度特征。此外,注意力机制分别应用于光谱、空间和空谱特征,进行特征细化,增强重要区域的特征响应。最后,将不同维度的细化特征联合输入至分类器进行分类。在Indian Pines和Salinas Valley数据集上利用5%和1%的样本进行实验,分别取得了98.40%和99.78%的总体精度,与其他六种网络架构相比,该模型在准确性和稳定性上都具有更优的表现。

关键词：混合特征提取注意力机制多维特征融合图像分类