检索结果-南通市图书馆

Three-dimensional fracture of UO2 ceramic pellets by phase field modeling

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 169-180页

作者： wei Xiong xuan Ye Hongzhang Cheng Xiaoming Liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education Tsinghua University State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences

Fracture is the primary failure type for the UO2ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional （3D） UO2ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

Central histaminergic system participates in the regulation of ventrolateral thalamic nucleus and its role in parkinsonian tremor

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Central histaminergic system participates in the regulation ...

Central Histaminergic System Participates in the Regulation of Ventrolateral Thalamic Nucleus and Its Role in Parkinsonian Tremor

2019中国生理学会学术年会暨张锡钧基金第十五届全国青年优秀生理学学术论文交流会及第十三届全国青年生理学工作者学术会议

作者：许寒婷 Xiao-Yang ZHANG wei-xuan xue Shu-Tao XIE Qian-Xing ZHUANG Hong-Zhao LI Jian-Jun WANG Jing-Ning ZHU State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology School of Life Sciences Institute for Brain Sciences Nanjing University

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Central Histaminergic System Participates in the Regulation ...

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

中国生理学会张锡钧基金第十五届全国青年优秀生理学学术论文交流及评奖会议;中国生理学会第十三届全国青年生理学工作者学术会议

作者： Han-Ting XU Xiao-Yang ZHANG wei-xuan xue Shu-Tao XIE Qian-Xing ZHUANG Hong-Zhao LI Jian-Jun WANG Jing-Ning ZHU State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology School of Life Sciences Institute for Brain Sciences Nanjing University

Parkinson’ s disease is the second most common neurodegenerative *** parkinsonian patients develop *** a traditional clinical target for deep brain stimulation in the treatment of parkinsonian tremor,the ventrolateral thalamus (VL) attracts increasing *** is an important neurotransmitter/modulator which is synthesized exclusively in the tuberomammillary nucleus (TMN) of the *** histamine levels alter with the pathological process of Parkinson's ***,the histaminergic system densely innervates the ***,little is

关键词： Central Histaminergic System Participates in the Regulation of Ventrolateral Thalamic Nucleus and Its Role in Parkinsonian Tremor Nucleus

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie Jing Zhang xue Fang Hongmei Luo Chuanhai Fu Zhiyi wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 2116-2128页

作者： Yuxue Mu Ning Zhang Dongyu wei Guoqing Yang Lilingxuan Yao Xinyue Xu Yang Li Junhui xue Zuoming Zhang Tao Chen Aerospace Clinical Medical Center School of Aerospace MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Aviation Medicine Xijing HospitalAir Force Medical UniversityXi’anShaanxi ProvinceChina Department of Emergency Medicine Wuhan No.1 HospitalWuhanHubei ProvinceChina Third Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina Fourth Regiment School of Basic MedicineAir Force Medical UniversityXi’anShaanxi ProvinceChina

A microgravity environment has been shown to cause ocular damage and affect visual acuity,but the underlying mechanisms remain ***,we established an animal model of weightlessness via tail suspension to examine the pathological changes and molecular mechanisms of retinal damage under *** 4 weeks of tail suspension,there were no notable alterations in retinal function and morphology,while after 8 weeks of tail suspension,significant reductions in retinal function were observed,and the outer nuclear layer was thinner,with abundant apoptotic *** investigate the mechanism underlying the degenerative changes that occurred in the outer nuclear layer of the retina,proteomics was used to analyze differentially expressed proteins in rat retinas after 8 weeks of tail *** results showed that the expression levels of fibroblast growth factor 2(also known as basic fibroblast growth factor)and glial fibrillary acidic protein,which are closely related to Müller cell activation,were significantly *** addition,Müller cell regeneration and Müller cell gliosis were observed after 4 and 8 weeks,respectively,of simulated *** findings indicate that Müller cells play an important regulatory role in retinal outer nuclear layer degeneration during weightlessness.

关键词： glial fibrous acidic protein gliosis Müller cells nerve growth factor neural differentiation neurodegeneration proteomic retinal degeneration retinal outer nuclear layer simulated weightlessness

在线全文

学校读者我要写书评

暂无评论

电子舌工作原理及应用综述

化工设计通讯 2018年第2期44卷 140-141页

作者：王栋轩卫雪娇刘红蕾河北农业大学渤海校区河北黄骅061100

随着化学检测技术和传感器技术的发展,电子舌技术越来越受到人们的广泛关注。因其快速、无伤、客观和应用范围广等特点,被应用于各种检测领域。对电子舌系统原理、优点和分类进行了阐述,并简单介绍了近几年电子舌在食品、药品和饮品领... 详细信息

随着化学检测技术和传感器技术的发展,电子舌技术越来越受到人们的广泛关注。因其快速、无伤、客观和应用范围广等特点,被应用于各种检测领域。对电子舌系统原理、优点和分类进行了阐述,并简单介绍了近几年电子舌在食品、药品和饮品领域的应用研究进展。

关键词：电子舌化学传感阵列电化学

Segmentation by Elastica Energy with L^(1) and L^(2) Curvatures: a Performance Comparison

在线全文

学校读者我要写书评

暂无评论

Numerical Mathematics(Theory,Methods and Applications) 2019年第1期12卷 285-311页

作者： xuan He wei Zhu xue-Cheng Tai Department of Mathematics University of AlabamaBox 870350TuscaloosaAL 35487USA Department of Mathematics Hong Kong Baptist UniversityKowloonTong KowloonHong Kong

In this paper,we propose an algorithm based on augmented Lagrangian method and give a performance comparison for two segmentation models that use the L^(1)-and L^(2)-Euler’s elastica energy respectively as the regularization for image *** capture contour curvature more reliably,we develop novel augmented Lagrangian functionals that ensure the segmentation level set function to be signed dis-tance functions,which avoids the reinitialization of segmentation function during the iterative *** the proposed algorithm and with the same initial contours,we compare the performance of these two high-order segmentation models and numerically verify the different properties of the two models.

关键词： Augmented Lagrangian method Euler’s elastica image segmentation

短链脂肪酸介导的肠骨轴在骨代谢中的研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

食品科学 2025年第2期46卷 260-267页

作者：张萱杨雪李新科孟璐王加启郑楠中国农业科学院北京畜牧兽医研究所农业农村部奶及奶制品质量安全控制重点实验室北京100193 中国农业科学院北京畜牧兽医研究所农业农村部奶产品质量安全风险评估实验室(北京)北京100193

随着全球老龄化加剧,骨质疏松症等与年龄相关的骨骼代谢疾病发病率不断上升,寻求安全有效的治疗干预方法至关重要。目前肠道微生物及其代谢产物调节骨代谢已成为研究的热点。短链脂肪酸(short-chain fatty acids,SCFAs)如乙酸、丙酸和... 详细信息

随着全球老龄化加剧,骨质疏松症等与年龄相关的骨骼代谢疾病发病率不断上升,寻求安全有效的治疗干预方法至关重要。目前肠道微生物及其代谢产物调节骨代谢已成为研究的热点。短链脂肪酸(short-chain fatty acids,SCFAs)如乙酸、丙酸和丁酸等,能够通过肠-骨轴发挥骨形成和骨吸收的调节作用,对骨稳态调节具有一定的积极作用,并能改善炎症性骨丢失。本文综述SCFAs通过内分泌、免疫、改善营养吸收等途径调控骨代谢稳态,以期为老年代谢性骨病的预防和治疗提供科学依据。

关键词：肠-骨轴短链脂肪酸肠道微生物骨代谢骨质疏松症

Soliton molecules for combined mKdV-type bilinear equation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2023年第10期75卷 1-9页

作者： Zhang-xuan Zhao Lu-wei Zhang wei Yang xue-Ping Cheng School of Information Engineering Zhejiang Ocean UniversityZhoushan 316022China Key Laboratory of Oceanographic Big Data Mining&Application of Zhejiang Province Zhoushan 316022China

Starting from the multi-soliton solutions obtained by the Hirota bilinear method,the soli ton molecule structures for the combined mKdV-type bilinear equation(Dt+∑n=1NαnDx2n+1)f*·f=0 are investigated using the velocity resonance *** two-soliton molecules of the mKdV-35 equation and the three-soliton molecules of the mKdV-357 equation are specifically demonstrated in this *** particular selections of the involved arbitrary parameters,especially the wave numbers,it is confirmed that,besides the usual multi-bright soliton molecules,the multi-dark soliton molecules and the mixed multibright-dark soliton molecules can also be *** addition,we discuss the existence of the multi-soliton molecules for the combined mKdV-type bilinear equation with more higher order nonlinear terms and *** results demonstrate that when N≥4,the combined mKdVtype bilinear equation no longer admits soliton molecules comprising more than four solitons.

关键词： soliton molecule combined mKdV-type bilinear equation Hirota bilinear method velocity resonance mechanism