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New classification of the anatomic variations of cystic artery during laparoscopic cholecystectomy

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World Journal of Gastroenterology 2007年第42期13卷 5629-5634页

作者： You-Ming Ding Bin wang wei-Xing wang ping wang Ji-Shen Yan Department of Hepatobiliary & Laparoscopic Surgery Renmin Hospital of Wuhan University Wuhan 430060 HubeiProvince China

AIM： To investigate the anatomic variations in the cystic artery by laparoscopy, and to provide a new classification system for the guidance of laparoscopic ***： Six hundred patients treated with laparoscopic cholecystectomy from June 2005 to May 2006 were studied retrospectively, The laparoscope of 30° （Stryker, American） was applied, Anatomic structures of cystic artery and conditions of Calot＇s triangle under laparoscope were recorded respectively,RESULTS： Laparoscopy has revealed there are many anatomic variations of the cystic artery that occur frequently. Based on our experience with 600 laparoscopic cholecystectomies, we present a new classification of anatomic variations of the cystic artery, which can be divided into three groups：（1） Calot＇s triangle type, found in 513 patients （85.5%）; （2） outside Calot＇s triangle, found in 78 patients （13%）; （3） compound type, observed in 9 patients （1.5%）.CONCLUSION： Our classification of the anatomic variations of the cystic artery uncontrollable cystic artery extrahepatic bile duct injury. will be useful for decreasing hemorrhage, and avoiding extrahepatic bile duct injury.

关键词： Cystic artery Laparoscopic cholecystectomy Bile duct injury Calot's triangle

Synthesis and Crystal Structure of a Novel 1D Chain-like Organic Inorganic Hybrid Rare Earth Derivative of Polyoxometalate: H_(0.5)[Sm(H_2O)_6]_(0.25)[Sm(H_2O)_5]_(0.25){[Sm(H_2O)_7][Sm(H_2O)_2-(DMSO)][SiW_(11)O_(39)]}·4.5H_2O

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Chinese Chemical Letters 2005年第12期16卷 1655-1658页

作者： Jun wei ZHAO Jing ping wang Jing Yang NIU School of Chemistry and Chemical Engineering Henan University Kaifeng 475001

A 1D chain-like organic-inorganic hybrid rare earth derivative of polyoxometalate H0.5[Sm（H2O）6]0.25[Sm（H2O）5]0.25{[Sm（H2O）7][Sm（H2O）2（DMSO）][SiW11O39]}·4.5H2O has been firstly synthesized by reaction of α-K8SiW11O39.13H2O, HClO4, Sm2O3 with dimethyl sulfoxide （DMSO） and characterized by elemental analysis, IR spectra and single crystal X-ray diffraction. The neighboring polyanionic units {[Sm（H2O）7][Sm（H2O）2（DMSO）][SiWHO39]}^2- are bridged together to a 1D chain structure by means of [Sm（H2O）2（DMSO）]^3＋ ion.

关键词： Silicotungstic acid polyoxometalate mono-vacant Keggin structure rare earth ions

Effects of Bifidobacterium supplementation on intestinal microbiota composition and the immune response in healthy infants

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World Journal of Pediatrics 2016年第2期12卷 177-182页

作者： Bing-Bing Wu Yi Yang Xiu Xu wei-ping wang Pediatrics Institute Key Laboratory of Neonatal DiseasesMinistry of HealthChildren's Hospital of Fudan University399 Wanyuan RoadShanghai 201102China Department of Pediatric Healthcare Children's Hospital of Fudan University399 Wanyuan RoadShanghai 201102China

Background:Intestinal microbiotas are thought to be the most important source of maturational stimuli to the development of the immune ***,few studies have focused on the development of T helper(Th)1 immune response and antibody response to vaccinations in healthy infants,especially in a large *** this randomized,double-blind control trial,we investigated the effects of Bifidobacterium longum BB536(BB536)supplementation on intestinal microbiota composition and the immune response in term ***:In total,300 healthy newborns were recruited,randomized and fed formula either supplemented with BB536 or with no *** samples were analyzed at months 2,4 and *** representative cytokine for Th1[interferon-γ(IFN-γ)]and Th2[interleukin-4(IL-4)]secretion cells were measured using enzyme-linked immunospot assay at 4 and 7 months of *** antibody response to vaccines was measured at months 7 and ***:A total of 264 infants completed the *** amount of bifidobacteria and the bifidobacteria/Enterobacteriaceae ratio(B/E)were signifi cantly higher in the BB536 supplementation group at months 2 and *** number of IFN-γsecretion cells and the ratio of IFN-γ/IL-4 secretion cells were increased in the BB536 supplementation group at 7 ***,the higher value of B/E in the early stages seems to be related to the increased Th1 *** difference was observed between groups in the antibody response after ***:BB536 has positive effects on establishing a healthy intestinal microbiota early in life,and it also plays an important role in improving the Th1 immune response.

关键词： intestinal microbiota probiotics supplementation term infants T helper 1/T helper 2 balance vaccination

A multi-paradigm decision modeling framework for combat system effectiveness measurement based on domain-specific modeling

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第5期14卷 311-331页

作者： Xiao-bo LI Yong-lin LEI Hans VANGHELUWE wei-ping wang Qun LI Institute of Simulation Engineering College of Information Systems and ManagementNational University of Defense Technology Department of Mathematics and Computer Science University of Antwerp

Decision modeling is an essential part of the combat system effectiveness simulation (CoSES), which needs to cope with the cognitive quality, diversity, flexibility, and higher abstraction of decision making. In this paper, a multi-paradigm decision modeling framework is proposed to support decision modeling at three levels of abstraction based on domain-specific modeling (DSM). This framework designs a domain-specific modeling language (DSML) for decision modeling to raise the abstraction level of modeling, transforms the domain-specific models to formalism-based models to enable formal analysis and early verification and validation, and implements the semantics of the DSML based on a Python scripts framework which incorporates the decision model into the whole simulation system. The case study shows that the proposed approach incorporates domain expertise and facilitates domain modeler's participation in CoSES to formulate the problem using DSML in the problem domain, and enables formal analysis and automatic implementation of the decision model in the solution domain.

关键词： Multi-paradigm modeling (MPM) Decision modeling Domain-specific modeling (DSM) Effectiveness measurement Model transformation

Hepatocellular carcinoma progression in hepatitis B virus-related cirrhosis patients receiving nucleoside(acid)analogs therapy:A retrospective cross-sectional study

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World Journal of Gastroenterology 2021年第17期27卷 2025-2038页

作者： Dan-Hong Yang wei-ping wang Qiang Zhang Hong-Ying Pan Yi-Cheng Huang Jia-Jie Zhang Department of Infectious Diseases Zhejiang Provincial People's HospitalPeople's Hospital of Hangzhou Medical CollegeHangzhou 310014Zhejiang ProvinceChina Postgraduate Department Bengbu Medical CollegeBengbu 233030Anhui ProvinceChina

BACKGROUND Antiviral therapy cannot completely block the progression of hepatitis B to hepatocellular carcinoma(HCC).Furthermore,there are few predictors of early HCC progression and limited strategies to prevent progression in patients with HBV-related cirrhosis who receive nucleos(t)ide analog(NA)*** The study aim was to clarify risk factors and the diagnostic value of alphafetoprotein(AFP)for HCC progression in NA-treated hepatitis B virus(HBV)-related cirrhosis *** In this retrospective cross-sectional study,we analyzed the clinical data of 266 patients with HBV-related cirrhosis who received NA treatment between February 2014 and April 2020 at Zhejiang Provincial People’s *** patients were divided into two groups,145 who did not progress to HCC(No-HCC group),and 121 who progressed to HCC during NA treatment(HCC group).The logistic regression analysis was used to analyze the risk factors of HCC *** diagnostic value of AFP for HCC was evaluated by receiver operating characteristic(ROC)curve *** Univariate analysis showed that age≥60 years(P=0.001),hepatitis B and alcoholic etiology(P=0.007),smoking history(P80 U/L(P=0.002),gamma-glutamyl transpeptidase>120 U/L(P=0.001),alkaline phosphatase>250 U/L(P=0.001),fasting blood glucose(FBG)≥6.16(mmol/L)(P=0.001)and Child-Pugh class C(P=0.005)were correlated with HCC *** multivariate analysis,age≥60 years[hazard ratio(HR)=3.089,95%confidence interval(CI):1.437-6.631,P=0.004],smoking history(HR=4.001,95%CI:1.836-8.716,P<0.01),family history of HBV-related HCC(HR=6.763,95%CI:1.253-36.499,P<0.05),lamivudine resistance(HR=2.949,95%CI:1.207-7.208,P=0.018),HBV DNA negative(HR=0.026,95%CI:0.007-0.139,P<0.01),FBG≥6.16 mmol/L(HR=7.219,95%CI:3.716-14.024,P<0.01)were independent risk factors of HCC *** of AFP for diagnosis

关键词： Hepatitis B virus Hepatocellular carcinoma Cirrhosis Risk factors Nucleos(t)ide analogs Progression

Automated Power Control for Virtualized Infrastructures

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Journal of Computer Science & Technology 2014年第6期29卷 1111-1122页

作者：文雨王伟平郭莉孟丹 Institute of Information Engineering Chinese Academy of Sciences CCF IEEE

Power control for virtualized enviromnents has is keeping underlying infrastructure in reasonably low power gained much attention recently. One of the major challenges states and achieving service-level objectives （SLOs） of upper applications as well. Existing solutions, however, cannot effectively tackle this problem for virtualized environments. In this paper, we propose an automated power control solution for such scenarios in hope of making some progress. The major advantage of our solution is being able to precisely control the CPU frequency levels of a physical environment and the CPU power allocations among virtual machines with respect to the SLOs of multiple applications. Based on control theory and online model estimation, our solution can adapt to the variations of application power demands. Additionally, our solution can simultaneously manage the CPU power control for all virtual machines according to their dependencies at either the application-level or the infrastructure-level. The experimental evaluation demonstrates that our solution outperforms three state-of-the-art methods in terms of achieving the application SLOs with low infrastructure power consumption.

关键词： power control virtualized infrastructure multi-tier application virtual machine service-level objective

Characteristic response of striatal astrocytes to dopamine depletion

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Neural Regeneration Research 2020年第4期15卷 724-730页

作者： Yao-Feng Zhu wei-ping wang Xue-Feng Zheng Zhi Chen Tao Chen Zi-Yun Huang Lin-Ju Jia Wan-Long Lei Department of Anatomy Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Institute of Medicine College of MedicineJishou UniversityJishouHunan ProvinceChina Periodical Center the Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Astrocytes and astrocyte-related proteins play important roles in maintaining normal brain function,and also regulate pathological processes in brain diseases and ***,the role of astrocytes in the dopamine-depleted striatum remains unclear.A rat model of Parkinson’s disease was therefore established by injecting 10μL 6-hydroxydopamine(2.5μg/μL)into the right medial forebrain *** staining was used to detect the immunoreactivity of glial fibrillary acidic protein(GFAP),calcium-binding protein B(S100B),and signal transducer and activator of transcription 3(STAT3)in the striatum,and to investigate the co-expression of GFAP with S100B and *** blot assay was used to measure the protein expression of GFAP,S100B,and STAT3 in the *** demonstrated that striatal GFAP-immunoreactive cells had an astrocytic appearance under normal conditions,but that dopamine depletion induced a reactive phenotype with obvious morphological *** normal striatum also contained S100B and STAT3 expression.S100B-immunoreactive cells were uniform in the striatum,with round bodies and sparse,thin ***3-immunoreactive cells presented round cell bodies with sparse processes,or were darkly stained with a large cell *** deprivation induced by 6-hydroxydopamine significantly enhanced the immunohistochemical positive reaction of S100B and *** striatal astrocytes expressed both S100B and *** dopamine deprivation increased the number of GFAP/S100B and GFAP/STAT3 double-labeled cells,and increased the protein levels of GFAP,S100B,and *** present results suggest that morphological changes in astrocytes and changes in expression levels of astrocyte-related proteins are involved in the pathological process of striatal dopamine *** study was approved by Animal Care and Use Committee of Sun Yat-sen University,China(Zhongshan Medical Ethics 2014 No.23)on September 22,2014.

关键词： 6-hydroxydopamine astrocyte dopamine depletion dopaminergic neurons Parkinson’s disease SIOOB STAT3 striatum

ThesourceparametersandsourcemechanismfortheJanuary5,1998JingyangearthquakewithMS=4.8

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Acta Seismologica Sinica(English Edition) 1998年第6期11卷 114-116页

作者： wei DONG wang ping wang Seismological Bureau of Shaanxi Province, Xi′an 710068, China

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关键词： Jingyang earthquake digital seismic network source parameters source mechanism

Relationships among hope, coping style and social support for breast cancer patients

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Chinese Medical Journal 2010年第17期123卷 2331-2335页

作者： ZHANG Jing GAO wei wang ping WU Zhong-hui Operating Room First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China

Background Breast cancer is one of the most common cancers in women, and its incidence seems to have gradually increased every year. During the treatment of breast cancer, patients suffer psychological morbidity, and hope is one important factor in maintaining psychological health. Therefore, in this study, we investigated the level of hope in Chinese women with breast cancer during chemotherapy and confirmed the relationships among hope, coping style, and social *** One hundred and fifty-nine inpatients with breast cancer who were undergoing chemotherapy in two affiliated hospitals of Harbin Medical University were recruited and investigated. Each patient completed the Herth Hope Index （HHI）, Jalowiec Coping Scale （JCS）, and the social support scale made by XIAO Shui-yuan, and provided general demographic *** The mean hope level of the 159 patients with breast cancer was 38.62±4.56. There was a statistical difference between the hope level and monthly income. Analysis of results from the Pearson test showed no relationship between the hope level and coping style; however, there were positive relationships between hope and optimism, hope and self-reliance, and hope and palliative coping styles. In contrast, negative relationships were found between hope and the fatalistic and emotional coping styles. The total score of hope and social support had significantly positive relationship for the three *** Patients with breast cancer achieved high levels of hope, with the level of hope being proportional to increase in the income. During chemotherapy, patients with breast cancer had adopted many coping styles.

关键词： hope coping style social support breast cancer