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A rare complex chromosomal rearrangement in an oligospermic male： a case report and review of the Chinese literature

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Asian Journal of Andrology 2014年第2期16卷 325-326页

作者： Ying-Jian Chen wei-wei Zhang Xiao-ming sun Cheng-Jin Hu Department of Laboratory Medicine General Hospital of Jinan Military Area JinanChina.

Dear Editor, Complex chromosome rearrangements （CCRs） are structural aberrations involving at least three chromosomes with three or more chromosomal breakpoints. CCRs are very rare events in the human population. As reviewed by Pellestor et al.,1 less than 255 cases of CCRs involving three or more chromosomes have been reported. In China, approximately 136 cases of CCRs, including 40 males with reproductive problems, have been reported up to the time this review was compiled.

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A broadband self-powered UV photodetector of aβ-Ga2O3/γ-CuI p–n junction

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Chinese Physics B 2022年第2期31卷 342-347页

作者： wei-ming sun Bing-Yang sun Shan Li Guo-Liang Ma Ang Gao wei-Yu Jiang Mao-Lin Zhang Pei-Gang Li Zeng Liu wei-Hua Tang Laboratory of Information Functional Materials and Devices School of ScienceBeijing University of Posts and TelecommunicationsBeijing 100876China College of Integrated Circuit Science and Engineering Nanjing University of Posts and TelecommunicationsNanjing 210023China National and Local Joint Engineering Laboratory for RF Integration and Micro-Packing Technologies Nanjing University of Posts and TelecommunicationsNanjing 210023China

The symmetric Ti/Au bi-layer point electrodes have been successfully patterned on theβ-Ga;O;films which are prepared by metal–organic chemical vapor deposition(MOCVD)and theγ-Cu I films which are prepared by *** fabricated heterojunction has a large open circuit voltage(Voc)of 0.69 V,desired for achieving self-powered operation of a *** by 254-nm ultraviolet(UV)light,when the bias voltage is-5 V,the dark current(Idark)of the device is 0.47 p A,the photocurrent(Iphoto)is-50.93 n A,and the photo-to-dark current ratio(Iphoto/Idark)reaches about 1.08×10;.The device has a stable and fast response speed in different wavelengths,the rise time(τr)and decay time(τd)are 0.762 s and 1.741 s under 254-nm UV light illumination,*** theτr andτd are 10.709 s and7.241 s under 365-nm UV light illumination,*** time-dependent(I–t)response(photocurrent in the order of10-10 A)can be clearly distinguished at a small light intensity of 1μW·cm;.The internal physical mechanism affecting the device performances is discussed by the band diagram and charge carrier transfer theory.

关键词： β-Ga2O3 γ-CuI heterojunction broadband photodetector self-power

Efficacy of probiotics or synbiotics for critically ill adult patients:a systematic review and meta-analysis of randomized controlled trials

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Burns & Trauma 2022年第1期10卷 671-684页

作者： Kai Wang Qin Zeng Ke-xun Li Yu Wang Lu Wang ming-wei sun Jun Zeng Hua Jiang Department of Acute Care Surgery Sichuan Provincial People’s HospitalUniversity of Electronic Science and Tech-nology of ChinaChengdu 610000China Department of Reproductive Medicine Sichuan Provincial Maternity and Child Health Care HospitalThe AffiliatedWomen’s and children’s Hospital of Chengdu Medical CollegeChengdu 610045China

Background:Microbial dysbiosis in critically ill patients is a leading cause of mortality and septic *** and synbiotics have emerged as novel therapy on gut microbiota to prevent septic ***,current evidence on their effects is *** work aims to systematically review the impact of probiotics or synbiotics in critically ill adult ***:A comprehensive search of the PubMed,CBM,Embase,CENTRAL,ISI,and CNKI databases was performed to identify randomized controlled trials that evaluate probiotics or synbiotics in critically ill *** quality assessment was based on the modified Jadad’s score scale and the Cochrane Handbook for Systematic Reviews of Interventions Version *** major outcome measure was *** outcomes included incidence of septic complications,sepsis incidence,length of intensive care unit(ICU)stay,incidence of non-septic complication,and ventilator *** synthesis was conduct by Review Manager ***:A total of 25 randomized controlled trials reporting on 5049 critically ill patients were *** the intervention group,2520 participants received probiotics or synbiotics,whereas 2529 participants received standard care or *** data from randomized controlled trials demonstrated a significant reduction in the incidence of ventilator-associated pneumonia(VAP)in the treatment group[(risk ratio(RR)0.86;95%confidence interval(CI):0.78-0.95;p<0.003,I^(2)=85%)].However,in the subgroup analysis,the reduction of incidence of VAP was only significant in patients receiving synbiotics(RR=0.61,95%CI:0.47-0.80,p=0.0004,I^(2)=40%)and not significant in those receiving only probiotics(RR=0.91,95%CI:0.82-1.01,p=0.07,I^(2)=65%).Moreover,sepsis incidence of critically ill patients was only significantly reduced by the addition of synbiotics(RR=0.41;95%CI:0.22-0.72,p=0.005,I^(2)=0%).The incidence of ICU-acquired infections was significantly reduced by the synbiotics the

关键词： Critically ill patients Probiotics Synbiotics Meta-analysis Systematic review Mortality Ventilator-associated pneumonia

Gut,metabolism and nutritional Support for COVID-19:Experiences from China

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Burns & Trauma 2020年第1期8卷 14-23页

作者： Ting Yuanand wei Chen Hua Jiang Jian-Cheng Zhang Jun Zeng Lu Wang Yu Wang Charles Damien Lu Lei Deng Hongfei Deng Kai Wang ming-wei sun Ping Zhou Ting Yuan wei Chen Institute for Emergency Medicine and Disaster Medicine Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaNo.32 Yi Huan Lu Xi Er DuanChengdu610072Sichuan ProvinceChina Emergency Intensive Care Unit Emergency Medicine CenterSichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaNo.32 Yi Huan Lu Xi Er DuanChengdu610072Sichuan ProvinceChina Department of Acute Care Surgery Emergency Medicine CenterSichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaNo.32Yi Huan Lu Xi Er DuanChengdu610072Sichuan ProvinceChina Medical Task Force of Sichuan Provincial People’s Hospital to Union Red Cross Hospital of Wuhan Wuhan430015China Department of Clinical Nutrition Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeNo.1 Shuai fu yuan Wang fu jing Dong cheng DistrictBeijing100730China

There is little research that focuses on the relationship between the gut,metabolism,nutritional support and *** a group of Chinese physicians,nutritionists and scientists working on the frontline treating COVID-19 patients,we aim to integrate our experiences and the current clinical evidence to address this pressing issue in this *** on our clinical observations and available evidence,we recommend the following ***,the Nutritional Risk Screening 2002 tool should be used routinely and periodically;for patients with a score≥3,oral nutritional supplements should be given ***,for patients receiving the antiviral agents lopinavir/ritonavir,gastrointestinal side effects should be monitored for and timely intervention ***,for feeding,the enteral route should be the first *** patients undergoing mechanical ventilation,establishing a jejunal route as early as possible can guarantee the feeding target being achieved if gastric dilatation ***,we suggest a permissive underfeeding strategy for severe/critical patients admitted to the intensive care unit during the first week of admission,with the energy target no more than 20 kcal/kg/day(for those on mechanical ventilation,this target may be lowered to 10–15 kcal/kg/day)and the protein target around 1.0–1.2 g/kg/*** the inflammatory condition is significantly alleviated,the energy target may be gradually increased to 25–30 kcal/kg/day and the protein target to 1.2–1.5 g/kg/***,supplemental parenteral nutrition should be used with ***,omega-3 fatty acids may be used as immunoregulators,intravenous administration of omega-3 fatty emulsion(10 g/day)at an early stage may help to reduce the inflammatory reaction.

关键词： COVID-19 Intensive care Nutritional risk Nutritional support Energy Protein Omega-3 fatty acids China Gut Metabolism

Coinage Metalides: A New Type of Excess Electron Compounds with Large Nonlinear Optical Responses and High Stability

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Coinage Metalides: A New Type of Excess Electron Compounds w...

铌酸锰-还原氧化石墨烯复合光催化剂的构建以及可见光下降解亚甲基蓝（英文）

2019中国化学会第十五届全国计算（机）化学学术会议

作者：张莉 Xiao-Ling Zhang wei-ming sun 中国农业大学 The Department of Basic Chemistry The School of Pharmacy Fujian Medical University

Based on the facially polarized all-cis 1,2,3,4,5,6-hexafluorocyclohexane (1),a new kind of excess electron compounds,namely M-1-M’(M=Li,Na,and K;M’=Cu,Ag,and Au) were designed and investigated in this *** compounds are the first examples of organometallic salts wherein the coinage metal atoms occupy the anionic sites,and thus termed coinage *** electronic features of these coinage metalides are very similar to those of M?1?M’(M,M’=Li,Na,and K) *** particular,these novel compounds M-1-M’exhibit higher stability (larger VIEs and E values) than the corresponding M?1?M’***,the M-1-Cuand M-1-Agcompounds also possess significantly large first hyperpolarizabilities (β) up to 90220 au,indicating that the Cu and Ag atoms can indeed serve as the excess electron acceptors of high-performance nonlinear optical (NLO) *** hope that this work will open up new possibilities for NLO material design by using coinage metal atoms as excess electron acceptor and,on the other hand,attract more experimental interest and efforts to synthesize such stable compounds in laboratory.

关键词： Coinage Metal Atoms Density Functional Theory Quantum Chemistry Electronic Structure

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无机化学学报 2017年第3期33卷 493-500页

作者：顾巍严铭孙林施伟东江苏大学化学化工学院镇江212013 江苏大学材料科学与工程学院镇江212013

通过水热法和光还原方法成功地制备了铌酸锰-还原氧化石墨烯复合光催化剂。这种复合光催化剂可以明显地提高光催化降解亚甲基蓝的光催化活性,降解效率在60 min内达到了78.2%,是单体铌酸锰降解效率的2倍。通过活性物质捕获实验的研究,增... 详细信息

通过水热法和光还原方法成功地制备了铌酸锰-还原氧化石墨烯复合光催化剂。这种复合光催化剂可以明显地提高光催化降解亚甲基蓝的光催化活性,降解效率在60 min内达到了78.2%,是单体铌酸锰降解效率的2倍。通过活性物质捕获实验的研究,增强的光催化性能可以归因于还原氧化石墨烯加速了光生电子-空穴的分离效率,进而解决了低光催化活性的问题。

关键词：铌酸锰-还原氧化石墨烯光催化剂亚甲基蓝可见光

Application of a paraplegic gait orthosis in thoracolumbar spinal cord injury

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Neural Regeneration Research 2016年第12期11卷 1997-2003页

作者： Lang Shuai Guo-hua Yu Zhen Feng Wan-song Wang wei-ming sun Lu Zhou Yin Yan Department of Rehabilitation the First Affiliated Hospital of Nanchang University

Paraplegic gait orthosis has been shown to help paraplegic patients stand and walk, although this method cannot be individualized for patients with different spinal cord injuries and functional recovery of the lower extremities. There is, however, a great need to develop individualized paraplegic orthosis to improve overall quality of life for paraplegic patients. In the present study, 36 spinal cord（below T4） injury patients were equally and randomly divided into control and observation groups. The control group received systematic rehabilitation training, including maintenance of joint range of motion, residual muscle strength training, standing training, balance training, and functional electrical stimulation. The observation group received an individualized paraplegic locomotion brace and functional training according to the various spinal cord injury levels and muscle strength based on comprehensive systematic rehabilitation training. After 3 months of rehabilitation training, the observation group achieved therapeutic locomotion in 8 cases, family-based locomotion in 7 cases, and community-based locomotion in 3 cases. However, locomotion was not achieved in any of the control group patients. These findings suggest that individualized paraplegic braces significantly improve activity of daily living and locomotion in patients with thoracolumbar spinal cord injury.

关键词： nerve regeneration spinal cord injury paraplegia brace thoracolumbar spine locomotion ability activity of daily living reciprocating gait orthosis hip-knee ankle foot orthosis knee-ankle foot orthosis ankle foot orthosis neural regeneration

Assemblies of Superatom clusters with Significant Nonlinear Optical Response

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Assemblies of Superatom clusters with Significant Nonlinear ...

Can Coinage Metal Atoms Be Capable of Serving as New Excess Electron Source of Alkalides with Considerable Nonlinear Optical Responses?

中国化学会第十二届全国量子化学会议

作者： wei-ming sun Di Wu Ying Li Zhi-Ru Li Institute of Theoretical Chemistry State Key Laboratory of Theoretical and Computational ChemistryJilin University

Superatoms1 are atomic clusters whose properties resemble those of atoms in the Periodic *** study of superatoms has ushered a new era in materials science where superatoms,instead of atoms,serve as the building blocks of novel nanostructured materials.2,3 Herein,a new series of superatom assemblies have been achieved by combining the superalkaline earth atom（CLi6）and superhalogen（Be F3）.Based on the resulting equilibrium structures,the stabilities and bonding nature as well as magnetic and nonlinear optical（NLO）properties of such assemblies have been systemically investigated by means of density functional theory（DFT）*** present investigation gives hints to scientists to extend the research in atomic dimension to direct the interaction between superatoms,and utilize superatoms as building blocks to synthesize novel meaningful materials with unusual properties such as nonlinear optical properties.

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Can Coinage Metal Atoms Be Capable of Serving as New Excess ...