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Hosoya and Merrifield-Simmons Indices in Random Polyphenyl Chains

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Acta Mathematicae Applicatae Sinica 2018年第1期34卷 163-172页

作者： wei-ling yang School of Mathematical Sciences Xiamen University

The Hosoya index of a graph is the total number of matchings in it. And the Merrifield-Simmons index is the total number of independent sets in it. They are typical examples of graph invariants used in mathematical chemistry for quantifying relevant details of molecular structure. In this paper, we obtain explicit analytical expressions for the expectations of the Hosoya index and the Merrifield-Simmons index of a random polyphenyl chain.

关键词： Hosoya index Merrifield-Simmons index random polyphenyl chain

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Line Graph Links

Acta Mathematicae Applicatae Sinica 2021年第4期37卷 706-716页

作者： wei-ling yang Xian-an JIN Fu-ji ZHANG School of Mathematical Sciences Xiamen UniversityXiamen361005China

It is well known that a shaded link diagram corresponds to a signed plane *** graph theory,line graph is an old and important concept originally introduced by *** in *** this paper we define the line graph link to be a link which has a diagram whose corresponding signed plane graph is a signed line *** main purpose of the paper is to illustrate the structure of planar line graphs,which permits us to deal with its signed Tutte polynomial and the Jones polynomials of line graph links.

关键词： line graphs planarity structure signed Tutte polynomial

The Infinitive Functioning As Adverbial

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信阳师范学院学报（哲学社会科学版） 1992年第1期12卷 104-117页

作者： Dong Bao-wei Hu yang-ling

The infinitive is a kind of non-finite forms of the verb. It has partly the character of a verb, partly that of a noun and also that of an adjective and adverb. It shows its verbal character by its capacity of taking the ordinary verb-modifiers, objects and adverbial adjuncts, exhibiting, at least in part, the distinctions of tense and voice. It shows its substantival character by its capacity of filling the same functions in a sentence as an ordinary noun. It can act in the function of adverbial as well as attribute, subject, object, predicative, apposition and so on. In this article, we will only discuss the question about the infinitive used as adverbial.

关键词： sentence tense verbal ordinary voice filling trouble listen phrase attribute

Characterization of Hepatic Drug-metabolizing Activities of Bama Miniature Pigs (Sus Scrofa Domestica): Comparison with Human Enzyme Analogs

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Characterization of Hepatic Drug-metabolizing Activities of ...

The protection of astrocyte against rotenone-induced dopaminergic neuron injury

中国实验动物学会第七届学术年会

作者： Jian Li, Yong Liu, Jiang-wei Zhang, Hong wei, and ling yang

We used various substrates and selective inhibitors of human cytochrome P450 (CYP) isozymes as probes to study the metabolism of liver microsomes from Chinese Bama miniature pigs. Nifedipine oxidation (NOD) and testosterone 6β-hydroxylation (6β-OHT) activities were similar between human liver microsomes and those from Bama miniature pigs. However, compared with those from humans, liver microsomes from Bama miniature pigs showed decreased phenacetin O-deethylation, coumarin 7-hydroxylation, and chlorzoxazone 6-hydroxylation activities, whereas dextromethorphan O-demethylation activity was increased. Ketoconazole selectively inhibited NOD and 6β-OHT activities in microsomes from Bama pigs, and 8-methoxypsoralen and tranylcypromine inhibited coumarin 7-hydroxylation in pig microsomes. However, furafylline and quinidine failed to selectively inhibit phenacetin O-deethylation and dextromethorphan O-demethylation in microsomes from Bama pigs, whereas chlormethiazole more efficiently inhibited coumarin 7-hydroxylation activity than chlorzoxazone 6-hydroxylation in pig microsomes. Our results suggest that liver microsomes from Chinese Bama miniature pigs are similar to those from humans in regard to metabolism of nifedipine and testosterone (both are probe substrates for human CYP3A4). In addition, chemical inhibitors used as specific probes for human P450 enzymes did not always show the same selectivity toward corresponding enzyme activities in liver microsomes from Bama pigs. However, ketoconazole (a potent inhibitor of human CYP3A4) could be used as a selective inhibitor probe for the NOD and 6β-OHT activities in liver microsomes from Chinese Bama miniature pigs.

关键词： 6β-OHT, testosterone 6β-hydroxylation CH, coumarin 7-hydroxylation CYP, cytochrome P450 CZH, chlorzoxazone 6-hydroxylation DMOD, dextromethorphan O-demethylation HPLC, high-performance liquid chromotography NOD, nifedipine oxidation POD, phenacetin O-deethylation UV, ultraviolet

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The protection of astrocyte against rotenone-induced dopamin...

中国神经科学学会第六届学术会议暨学会成立十周年庆祝大会

作者： wei ling-rong, yang Hui Beijing Institute for Neuroscience Capital University of Medical Sciences, Beijing

＜正＞Parkinson disease （PD） is a common neurodegenerative disorder characterized by the progressive loss of the dopaminergic neurons in the substantia nigra pars compacta （SNpc）. The pathological process is associated with a astrocyte response. However, the function of astrocytes neuron degenerative process is still a mysterious.

关键词： astrocyte neuron neuroprotection oxidative stress

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基于总体平均经验模态分解算法的自适应改进

振动与冲击 2017年第11期36卷 215-223页

作者：徐健周志祥唐亮冉杰何杰重庆交通大学土木工程学院重庆404100 南充市住房和城乡建设局 637000 西南交通大学土木工程学院成都610031

目前较为广泛使用的总体平均经验模态分解算法(EEMD)不能实现桥梁结构响应信号的自适应分解和重构,基于此,针对EEMD算法的不足,提出了能够实现桥梁结构响应信号自适应分解与重构的改进算法:首先引入自适应极值点匹配延拓算法以抑制端点... 详细信息

目前较为广泛使用的总体平均经验模态分解算法(EEMD)不能实现桥梁结构响应信号的自适应分解和重构,基于此,针对EEMD算法的不足,提出了能够实现桥梁结构响应信号自适应分解与重构的改进算法:首先引入自适应极值点匹配延拓算法以抑制端点效应;再对分解信号进行聚类分析以避免模态混叠现象;最后利用各本征模态函数(IMF)对应的信息熵、能量密度和平均周期构建筛选有效IMF分量的指标(有效程度系数),以实现有效IMF分量的自动筛选,再利用筛选出的有效分量对桥梁结构响应信号进行重构。模拟信号和简支梁桥仿真算例表明,所提改进算法能够更有效、更准确的实现桥梁结构响应信号的自适应分解与重构。

关键词：桥梁结构模态分解算法端点效应聚类分析信号重构

Acute and chronic excitotoxicity in ischemic stroke and late-onset Alzheimer's disease

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Neural Regeneration Research 2025年第7期20卷 1981-1988页

作者： Shan Ping Yu Emily Choi Michael QJiang ling wei Department of Anesthesiology Emory University School of MedicineAtlantaGAUSA Center for Visual and Neurocognitive Rehabilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke and Alzheimer's disease are common neurological disorders and often occur in the same *** comorbidity of the two neurological disorders represents a grave health threat to older *** review presents a brief background of the development of novel concepts and their clinical *** activity of glutamatergic N-methyl-D-aspartate receptors and N-methyl-D-aspartate receptor-mediated Ca^(2+)influx is critical for neuronal *** ischemic insult induces prompt and excessive glutamate release and drastic increases of intracellular Ca^(2+)mainly via N-methyl-D-aspartate receptors,particularly of those at the extrasynaptic *** Ca^(2+)-evoked neuronal cell death in the ischemic core is dominated by necrosis within a few hours and days known as acute ***,mild but sustained Ca^(2+)increases under neurodegenerative conditions such as in the distant penumbra of the ischemic brain and early stages of Alzheimer's disease are not immediately toxic,but gradually set off deteriorating Ca^(2+)-dependent signals and neuronal cell loss mostly because of activation of programmed cell death *** on the Ca^(2+)hypothesis of Alzheimer's disease and recent advances,this Ca^(2+)-activated“silent”degenerative excitotoxicity evolves from years to decades and is recognized as a unique slow and chronic *** N-methyl-D-aspartate receptor subunit GluN3A,primarily at the extrasynaptic site,serves as a gatekeeper for the N-methyl-D-aspartate receptor activity and is neuroprotective against both acute and chronic *** stroke and Alzheimer's disease,therefore,share an N-methyl-D-aspartate receptor-and Ca^(2+)-mediated mechanism,although with much different time *** is thus proposed that early interventions to control Ca^(2+)homeostasis at the preclinical stage are pivotal for individuals who are susceptible to sporadic late-onset Alzheimer's disease and Alzheimer's disease-related

关键词： Ca^(2+)hypothesis cognitive deficits hyperactivity late-onset Alzheimer's disease neurodegeneration N-methyl-D-aspartate receptors N-methyl-D-aspartate receptor subunits pathogenesis preventive treatment

Coagulation indices and fibrinogen degradation products as predictive biomarkers for tumor-node-metastasis staging and metastasis in gastric cancer

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 110-120页

作者： Yi-Qing Shen Qiu-Wan wei Yi-Ren Tian Yun-Zhi ling Min Zhang Clinical Laboratory Civil Aviation Shanghai HospitalGubei Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200000China Clinical Laboratory Tongji Hospital of Tongji UniversityShanghai 200000China

BACKGROUND Gastric cancer(GC)is a prevalent malignancy with a substantial health burden and high mortality rate,despite advances in prevention,early detection,and *** with the global average,Asia,notably China,reports disproportionately high GC *** disease often progresses asymptoma-tically in the early stages,leading to delayed diagnosis and compromised ***,it is crucial to identify early diagnostic biomarkers and enhance treatment strategies to improve patient outcomes and reduce *** Retrospectively analyzed the clinical data of 148 patients with GC treated at the Civil Aviation Shanghai Hospital between December 2022 and December *** associations of coagulation indices-partial thromboplastin time(APTT),prothrombin time(PT),thrombin time(TT),fibrinogen,fibrinogen degradation products(FDP),fasting blood glucose,and D-dimer(D-D)with TNM stage and distant metastasis were *** Prolongation of APTT,PT,and TT was significantly correlated with the GC TNM ***,abnormal coagulation system activation was closely related to disease *** FDP and D-D were significantly associated with distant metastasis in GC(P<0.05),suggesting that increased fibrinolytic activity contributes to increased metastatic *** Our Results reveal coagulation indices,FDPs as GC biomarkers,reflecting abnormal coagulation/fibrinolysis,aiding disease progression,metastasis prediction,and helping clinicians assess thrombotic risk for early intervention and personalized treatment plans.

关键词： Coagulation indexes Fibrinogen degradation products Gastric cancer Tumor-node-metastasis staging Distant metastasis

逆向工程中基于三目视觉自动提取并构造复杂曲面边界技术

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机器人 2002年第1期24卷 66-70,85页

作者：何炳蔚林志航杨明顺陈琨西安交通大学CIMS中心 710049

在逆向工程中复杂曲面零件表面的几何模型的构造是研究重点之一，根据零件表面的数字化数据提取零件表面的边界是构造零件几何模型的关键步骤．本文提出基于三目视觉方法来提取和构造复杂曲面边界的技术．从一幅图像中提取反映物体边... 详细信息

在逆向工程中复杂曲面零件表面的几何模型的构造是研究重点之一，根据零件表面的数字化数据提取零件表面的边界是构造零件几何模型的关键步骤．本文提出基于三目视觉方法来提取和构造复杂曲面边界的技术．从一幅图像中提取反映物体边界的特征点，再利用图像匹配方法得到这些特征点的空间坐标，最后以这些特征点构造出物体边界Ｂ样条曲线．

关键词：逆向工程计算机辅助设计复杂曲面边界几何模型三目视觉自动提取