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卷烟工艺风力负压波动分析与对策

山东工业技术 2024年第2期 61-64页

作者：李帅刁维龙王晓华王东陈飞云山东中烟工业有限责任公司青州卷烟厂山东潍坊262500

目前国内大多数卷烟厂采用模块化扁布袋除尘器实现集中工艺风力与除尘,除尘器配置的脉冲喷吹清灰系统周期性的喷射压缩空气进入除尘布袋,造成卷烟工艺风力负压规律性波动,影响烟支卷制质量。为了解决以上不足,通过优化改造,实现独立控... 详细信息

目前国内大多数卷烟厂采用模块化扁布袋除尘器实现集中工艺风力与除尘,除尘器配置的脉冲喷吹清灰系统周期性的喷射压缩空气进入除尘布袋,造成卷烟工艺风力负压规律性波动,影响烟支卷制质量。为了解决以上不足,通过优化改造,实现独立控制每列喷吹电磁阀的脉冲信号通断,使得两列同序号的电磁阀不同时工作,分时喷吹,每次喷吹时减少一半的压缩空气流量,从而降低脉冲喷吹对负压的波动幅度,保障烟支卷制质量的一致性。

关键词：除尘器脉冲喷吹清灰工艺风力压力波动

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航天诱变葛麻姆SP1代群体遗传变异分析

中国中药杂志 2024年第14期49卷 3736-3748页

作者：胡继丹董丽华朱卫丰王斌陈一鸣王晓云朱玉野葛菲江西中医药大学药学院江西南昌330004

为探讨太空环境对葛麻姆Pueraria montana的诱变效应,筛选出生长状态佳、异黄酮成分含量高的优良种质,实验对79株航天葛麻姆和10株对照葛麻姆进行农艺性状观测、花朵异黄酮成分与AFLP荧光分子标记,用Excel 2019、SPSS 25.0、NTSYSpc-2.... 详细信息

为探讨太空环境对葛麻姆Pueraria montana的诱变效应,筛选出生长状态佳、异黄酮成分含量高的优良种质,实验对79株航天葛麻姆和10株对照葛麻姆进行农艺性状观测、花朵异黄酮成分与AFLP荧光分子标记,用Excel 2019、SPSS 25.0、NTSYSpc-2.11F、Popgen 32等软件进行遗传多样性分析并聚类。结果表明,航天组的叶片毛姿态与花结构等2个性状发生变化,数量性状的CV、H′均高于对照组,聚类后有5株航天葛麻姆分出。航天组共有10株葛麻姆花的6″-O-木糖鸢尾苷与鸢尾苷显著高于对照组,二者总量均超过11%,聚类后共有9株航天葛麻姆分出。从64对引物中筛选出9对多态性引物,多态性位点数共1620个,多态位点百分率(PPL)平均值为83.33%;Nei′s基因多样性指数(H)平均值为0.1922、Shannon′s信息指数(I)平均值为0.3052,聚类后有4株航天植株分出。综合筛选结果,航天组30号、66号、89号葛麻姆受到太空环境的诱变作用较大,主要表现为生长状况更佳、花朵异黄酮含量更高,且30号有花结构变异、花重达到对照组2倍,可作为后续试验的重点研究材料。

关键词：航天育种农艺性状含量测定扩增片段长度多态性(AFLP) 葛麻姆遗传多样性

A bioartificial transgenic porcine whole liver expressing human proteins alleviates acute liver failure in pigs

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Hepatobiliary & Pancreatic Diseases International 2023年第3期22卷 270-281页

作者： wei-song Xue Hao-Jie Zhang Jing-Jing Ke Yu Fu Qing Peng Li Li Yi Gao Ke-Bo Zhong General Surgery Center Department of Hepatobiliary SurgeryⅡGuangdong Provincial Research Center for Artificial Organ and Tissue EngineeringGuangzhou Clinical Research and Transformation Center for Artificial LiverInstitute of Regenerative MedicineZhujiang HospitalSouthern Medical UniversityGuangzhou 510280China Department of General Surgery&Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor Nanfang HospitalThe First School of Clinical MedicineSouthern Medical UniversityGuangzhou 510515China People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine Fuzhou 350000China State Key Laboratory of Organ Failure Research Southern Medical UniversityGuangzhou 510280China

Background:Preventing heterologous protein influx in patients is important when using xenogeneic bioartificial livers(BALs)to treat liver *** development of transgenic porcine livers synthesizing human proteins is a promising approach in this ***,we evaluated the safety and efficacy of a transgenic porcine liver synthesizing human albumin(h ALB)and coagulation factor VII(h FVII)within a bioartificial ***:Tibetan miniature pigs were randomly subjected to different interventions after surgeryinduced partially ischemic liver *** A(n=4)was subjected to basic treatment;group B(n=4)was to standard medical treatment and wild-type porcine BAL perfusion,and group C(n=2)was to standard medical treatment and transgenic BAL *** parameters,coagulation status,survival time,and pathological changes were *** of h ALB and h FVII were detected using immunohistochemistry and enzyme-linked immunosorbent ***:The survival time in group A was 9.75±1.26 days;this was shorter than that in both perfused groups,in which all animals reached an endpoint of 12 days(P=0.006).Ammonia,bilirubin,and lactate levels were significantly decreased,whereas albumin and fibrinogen levels were increased after perfusion(all P<0.05).h ALB and h FVII were detected in transgenic BAL-perfused pig serum and ex vivo in the liver ***:The humanized transgenic pig livers could synthesize and secrete h ALB and h FVII ex vivo in a whole organ-based bioartificial system,while maintaining their metabolism,detoxification,transformation,and excretion functions,which were comparable to those observed in wild-type porcine ***,the use of transgenic bioartificial whole livers is expected to become a new approach in treating acute liver failure.

关键词： Acute liver failure Transgenic pig Bioartificial liver Xenotransplantation

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皮瓣缺血再灌注损伤的发病机制及治疗进展

中国组织工程研究 2025年第6期29卷 1230-1238页

作者：何波陈文马岁录何志军宋渊李金鹏刘涛魏晓涛王威威谢婧南阳市中医院河南省南阳市473007 甘肃省中医院甘肃省兰州市730050 西安市中医院陕西省西安市710000 甘肃中医药大学甘肃省兰州市730030

背景:皮瓣移植技术是治疗严重组织缺损的常用外科手术方式,但术后因缺血再灌注损伤容易引发皮瓣坏死,因此提高移植皮瓣的存活率仍是目前重要的研究课题。目的:综述皮瓣缺血再灌注损伤的发病机制及最新治疗进展。方法:检索CNKI、万方和Pu... 详细信息

背景:皮瓣移植技术是治疗严重组织缺损的常用外科手术方式,但术后因缺血再灌注损伤容易引发皮瓣坏死,因此提高移植皮瓣的存活率仍是目前重要的研究课题。目的:综述皮瓣缺血再灌注损伤的发病机制及最新治疗进展。方法:检索CNKI、万方和PubMed数据库中2014-2024年发表的相关文献,中文检索词为“皮瓣,缺血再灌注损伤,炎症反应,氧化应激反应,Ca^(2+)超载,细胞凋亡,间充质干细胞,富血小板血浆,信号通路,冲击波,预处理”,英文检索词为“flap,ischemia-reperfusion injury,inflammatory response,oxidative stress,Ca^(2+)overload,apoptosis,mesenchymal stem cells,platelet-rich plasma,signaling pathways,Shock wave,Pretreatment”。通过阅读文章剔除研究内容与文章主题关系不大、质量较差及内容陈旧文献,最终纳入77篇文献进行归纳总结。结果与结论:皮瓣缺血再灌注损伤损伤可能与炎症反应、氧化应激反应、Ca^(2+)超载、细胞凋亡等病理因素有关,引起皮瓣血管内皮细胞凋亡、血管损伤和微循环障碍,最终导致皮瓣坏死。研究发现,间充质干细胞移植、富血小板血浆、信号通路调节剂、冲击波及预处理等治疗方法均可以从不同方向在不同程度上缓解皮瓣缺血再灌注损伤,降低移植皮瓣的坏死率和坏死面积。关于皮瓣缺血再灌注损伤的治疗方法虽然很多,然而临床还未形成统一有效的治疗方法,各种治疗方法的优缺点也未进行对比研究,并且大部分研究都停留在动物实验阶段,临床观察研究甚少,因此未来还需要进行大量研究,逐步由动物实验向临床迈进,以便更好地为临床服务。

关键词：皮瓣缺血再灌注损伤炎症反应氧化应激反应 Ca^(2+)超载细胞凋亡间充质干细胞富血小板血浆信号通路冲击波预处理

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2024年1月23日乌什M_(S)7.1地震序列类型判定

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内陆地震 2024年第2期38卷 121-127页

作者：马倩雯宋春燕聂晓红魏芸芸新疆维吾尔自治区地震局新疆乌鲁木齐830011

利用新疆地震台网观测数据,对2024年1月23日乌什M_(S)7.1地震序列进行分析,结果显示乌什地震序列的余震活动丰富,频度衰减较快。通过历史地震序列类比、序列参数(b值、p值、h值)、等待时间、震级差和能量比等参数的跟踪分析,判断此次乌... 详细信息

利用新疆地震台网观测数据,对2024年1月23日乌什M_(S)7.1地震序列进行分析,结果显示乌什地震序列的余震活动丰富,频度衰减较快。通过历史地震序列类比、序列参数(b值、p值、h值)、等待时间、震级差和能量比等参数的跟踪分析,判断此次乌什M_(S)7.1地震序列为主震―余震型。从历史地震序列类型的早期定性判定到地震序列参数定量计算的跟踪判定乌什7.1级地震序列类型,对地震序列类型的跟踪判定有一定参考作用。

关键词：乌什M_(S)7.1地震地震序列强余震早期趋势判定

Scientific publications on orthopedic surgery from three major East Asian countries(2012-2021)

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世界骨科杂志:英文版 2023年第8期14卷 641-650页

作者： wei-You Chen Xin Xiao Cheng Pan Fei-Hong huang Hong-Yuan Xu Qing-Jun wei hua Jiang Division of Spine Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Orthopedic Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND East Asia is the most dynamic region in the world and includes three major countries:Japan,South Korea and *** to rapid economic growth,orthopedics research in East Asia has achieved great advances during the past 10 ***,the current status of orthopedic research in Japan,South Korea and China is still *** To understand the current status of orthopedic research in Japan,South Korea,and *** Journals listed in the“Orthopedics”category of Science Citation Index Expanded subject categories were *** PubMed and Web of Knowledge electronic databases were searched to identify scientific publications from the selected journals written by researchers from Japan,South Korea and China.A systematic analysis was conducted to analyze orthopedic research articles published in the three countries based on the number of articles,study design,impact factors(IFs)and ***,we also ranked the top 10 countries worldwide with the highest publications in the past 10 ***,we ranked the top 10 countries with the highest number of publications in the world in the past 10 *** analyses were performed using SPSS 20.0 software(SPSS Inc.,Chicago,IL,United States),and statistical results are given in Tables and *** Kruskal-Wallis test and the Mann-Whitney test were used to detect differences between *** tendency regarding the number of articles was analyzed by curvilinear regression.A two-tailed P<0.05 was considered *** From 2012-2021,a total of 144518 articles were published in the 86 selected orthopedic *** this period,the number of worldwide published orthopedic articles has shown an annual increasing trend.A total of 27164 orthopedic research articles were published by Japan,South Korea and China during the past 10 years;44.32%were from China,32.98%were from Japan,and 22.70%were from South *** 2012 to 2021,the annual number of articles markedly in

关键词： Japan South Korea China Medical publication Orthopedics Research

Comparison of coronary plaque composition among patients with acute coronary syndrome and stable coronary artery disease

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Chinese Medical Journal 2008年第6期121卷 534-539页

作者： LI Xin-ming huaNG Cong-xin WANG Tian-song ZhuaNG Shao-wei ZHOU hua TIAN Bei Department of Cardiology Renmin Hospital of Wuhan UniversityWuhan Hubei 320089 China Department of Cardiology Shanghai East Hospital Affiliated toTongji University Shanghai 200120 China

Background The identification of vulnerable plaques before rupture is an important clinical goal. The purpose of the present study was to assess the difference in plaque composition among patients with acute coronary syndrome （ACS） and stable coronary artery disease （SCAD） by intravascular ultrasound virtual histologic analysis. Methods One hundred and thirty-nine patients were divided into ACS group and SCAD group according to clinical presentation. A total of 229 de novo lesions with 〉50% stenosis in native coronary arteries with diameters 〉2.5 mm were studied with intravascular ultrasonography. Geometric and compositional data were obtained using intravascular ultrasound virtual histology software. Results There were no significant differences in overall lesions for fibrous （（52.0±11.9）% vs （54.3±8.5）%, P〉0.05）, fibrolipidic （（12.3±10.1）% vs （13.8±9.5）%,P〈0.05）, calcium （（14.0±9.1）% vs （19.3±13.1）%, P〉0.05）, or necrotic core （（22.0±11.1）% vs （19.7±5.4）%, P〉0.05） percentages in ACS and SCAD patients, respectively. There were also no significant differences in culprit lesions for fibrous （（46.4±12.0）% vs （53.6±8.8）%, P〉0.05）, fibrolipidic （（9.1±9.0）% vs （12.9±9.7）%, P〉0.05）, calcium （（16.6±9.7）% vs （21.8±26.3）%, P〉0.05）, or necrotic core （（28.0±12.6）% vs （20.6±5.2）%, P〉0.05） percentages in ACS and SCAD patients, respectively. High density lipoprotein-cholesterol levels 〉1.04 mmol/L were associated with more fibrolipidic （（14.5±10.4）% vs （7.1±6.5）%, P〈0.05） and less necrotic core （（20.6±9.7）% vs （27.9±12.6）%,P〈0.05） percentages in the cohort with ACS. Conclusions In this study, coronary plaque composition assessed by intravascular ultrasound virtual histologic analysis was not significantly different between ACS and SCAD patients. The anatomic relationship of the specific plaque components to the lumen of the vessel was more important than the quantitative information of plaque composition for plaque stability.

关键词： coronary plaque composition acute coronary syndrome coronary artery disease ultrasonography, interventional arteriosclerosis

Delay-dependent Stability for Systems with Fast-varying Neutral-type Delays via a PTVD Compensation

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自动化学报 2010年第1期36卷 147-152页

作者： LIU Zhen-wei ZHANG hua-Guang Key Laboratory of Integrated Automation for the Process Industry Ministry of Education Shenyang 110004 P.R. china College of Information Science and Engineering Northeastern University Shenyang 110004 P.R. China

The stability for a class of linear neutral systems with time-varying delays is studied in this paper,where delay in neutral-type term includes a fast-varying case(i.e.,the derivative of delay is more than one),which has never been considered in current *** less conservative delaydependent stability criteria for this system are proposed by applying new Lyapunov-Krasovskii functional and novel polynomials with time-varying delay(PTVD)compensation *** aim to deal with systems with fast-varying neutral-type delay can be achieved by using the new *** benefit brought by applying the PTVD compensation technique is that some useful elements can be included in criteria,which are generally ignored when estimating the upper bound of derivative of Lyapunov-Krasovskii functional.A numerical example is provided to verify the effectiveness of the proposed results.

关键词：稳定性稳定标准时滞补偿技术线性中立系统

骨折延迟愈合与骨不连现状与趋势:一项运用Citespace文献计量学及数据可视化研究

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中国医药导刊 2024年第2期26卷 181-192页

作者：熊伟程凌李华南李松邵子晨孙伟康江西省南昌市洪都中医院康复医学科江西南昌330008 江西中医药大学附属医院科研科江西南昌330008 江西中医药大学临床医学院江西南昌330008

目的:使用文献计量学及数据可视化分析技术,对骨折延迟愈合与骨不连的相关文献进行综合分析,总结该领域的研究现状及前沿动态,并推测未来发展趋势。方法:检索Web of Science核心数据库中2002年1月1日至2023年12月31日的骨折延迟愈合与... 详细信息

目的:使用文献计量学及数据可视化分析技术,对骨折延迟愈合与骨不连的相关文献进行综合分析,总结该领域的研究现状及前沿动态,并推测未来发展趋势。方法:检索Web of Science核心数据库中2002年1月1日至2023年12月31日的骨折延迟愈合与骨不连文献作为研究对象,使用Citespace软件对相关文献发表的国家、研究机构、杂志、作者、关键词等信息进行数据分析及可视化分析。结果:符合检索条件的文献9403篇,符合纳入标准的为9183篇,该领域发文量呈上升趋势,发达国家和相关国家的研究机构在该领域的研究中占据主导地位,但中国及上海交通大学等机构则在该领域发展迅速,处于追赶地位,频次最高的关键词为managemen(t治疗),关键词共形成15个聚类,突现关键词25个。结论:骨折延迟愈合与骨不连研究处于不断发展的状态,逐渐从手术治疗转向对疾病的发病机制及骨修复与再生领域的研究,研究层次不断加深。骨修复与再生将成为该领域未来研究的主要趋势。

关键词：骨折延迟愈合骨不连 Citespace 文献计量学数据可视化