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Human influence on the duration of extreme temperature events in Asia's hotspot regions

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Advances in Climate Change Research 2024年第2期15卷 312-326页

作者： Zi-Meng WANG Hong-Yun MA wei LI hai-Shan chen Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)/Key Laboratory of Meteorological Disaster Ministry of Education(KLME)Nanjing University of Information Science and TechnologyNanjing 210044China

Observations and models indicate that human activities exert a considerable impact on the frequency and intensity of extreme temperature events,which are associated with global ***,changes in the duration of extreme temperature events and their association with human influence have not been considered in most ***,the possible relationship between the observed changes in the warm and cold spell duration(WSDI and CSDI)in hotspot regions during 1960-2014 and human influence was investigated based on the NCEP/NCAR reanalysis version 1 and Coupled Model Inter-comparison Project Phase 6(CMIP6)*** projection based on these attribution results was also *** optimal fingerprinting technique was used to compare observed changes in WSDI and CSDI to simulated changes averaged across eight CMIP6 *** show that anthropogenic(ANT)forcing contributed to the observed increase in WSDI in the three hotspot regions(West Asia,South Asia and Southeast Asia),with the majority of the changes being attributed to greenhouse gas ***,a generally weak ANT signal can be observed in the decreasing trend of CSDI and can be detected in South and Southeast *** influence of aerosol forcing remains undetected in either WSDI or CSDI,which differs from the results for frequency and intensity of extreme *** attribution results revealed that the constrained projection of WSDI is lower than the raw projection for 2015-2100 in West Asia and Southeast ***,no differences in future CSDI changes are found in Southeast Asia between the constrained and raw projections.

关键词： Extreme temperature events Duration Detection attribution Constraint projection Hotspot regions

Essential thrombocythemia with non-ST-segment elevation myocardial infarction as the first manifestation:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7422-7428页

作者： Zhi-Ming Wang wei-hai chen Yan-Ming Wu Lin-Quan Wang Fu-Long Ye Ren-Lin Yin Department of Cardiology Suzhou Ninth People's HospitalSoochow UniversitySuzhou 215200Jiangsu ProvinceChina

BACKGROUND We report a case of essential thrombocythemia(ET)in a 44-year-old male who exhibited non-ST-segment-elevation myocardial infarction(NSTEMI)as the first manifestation without known cardiovascular risk factors(CVRFs).For the first time,we reported a left main trifurcation lesion in NSTEMI caused by ET,including continuous stenosis lesions from the left main to the ostial left anterior descending(LAD)artery and an obvious thrombotic lesion in the ostial and proximal left circumflex(LCX)*** was 60%diffuse stenosis in the left main(LM)that extended to the ostial LAD,thrombosis of the ostial LAD and proximal LCX,and 90%stenosis in the proximal *** the operation,thrombus aspiration was performed,but no obvious thrombus was *** the kissing balloon technique(KBT)in the LCX and LM unexpectedly increased the narrowness of the ***,the single-stent crossover technique,final kissing balloon technique and proximal optimization technique(POT)were *** the second day after percutaneous coronary intervention(PCI),the number of platelets(PLTs)still increased significantly to as high as 696×10^(9)/*** bone marrow biopsy done later,together with JAK2(exon 14)V617F mutation,confirms the diagnosis of *** was administered to inhibit bone marrow proliferation to control the number of *** SUMMARY A 44-year-old male patient went to a local hospital for treatment for intermittent chest pain occurring over 8 *** examination at the local hospital revealed elevated cTnI and significantly elevated ***,he was diagnosed with acute myocardial infarction and transferred to our hospital for emergency interventional treatment by *** the operation,thrombus aspiration,the single-stent crossover technique,final kissing balloon technique and POT were *** antiplatelet therapy comprising aspirin and ticagrelor was used after *** of mutated JAK2 V617F and bone marrow biopsy shown the onset o

关键词： Essential thrombocythemia Non-ST-segment-elevation myocardial infarction Percutaneous coronary intervention Hydroxyurea Case report

2.3 μm nanosecond passive Q-switching of an LD-pumped Tm:YLF laser using gold nanorods as a saturable absorber

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Frontiers of Information Technology & Electronic Engineering 2021年第3期22卷 312-317页

作者： Fu-yan WU Shi-qiang WANG hai-wei chen hai-tao HUANG School of Physics and Electronic Engineering Jiangsu Normal UniversityXuzhou 221116China

Developing new saturable absorbers for use in the mid-infrared region has practical significance for short-pulsed lasers and related scientific and industrial *** performance of gold nanorods(GNRs)as saturable absorbers at novel mid-infrared wavelengths needs to be evaluated even though these benefit from ultrafast nonlinear responses and broadband saturable *** Q-switching of an LD-pumped 2.3μm Tm:YLF laser using GNRs was successfully realized in this *** with an 843 ns pulse width and a 6.67 kHz repetition rate were achieved using this Q-switched *** showed that GNRs provide promising passive Q-switches for 2.3μm Tm-doped lasers.

关键词： Gold nanorods Passive Q-switching 2.3μm Tm-doped laser materials

Computational tools for plant genomics and breeding

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Science China(Life Sciences) 2024年第8期67卷 1579-1590页

作者： hai Wang Mengjiao chen Xin wei Rui Xia Dong Pei Xuehui Huang Bin Han State Key Laboratory of Maize Bio-breeding Frontiers Science Center for Molecular Design BreedingJoint International Research Laboratory of Crop Molecular BreedingNational Maize Improvement CenterCollege of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China Sanya Institute of China Agricultural University Sanya 572025China hainan Yazhou Bay Seed Laboratory Sanya 572025China State Key Laboratory of Tree Genetics and Breeding Key Laboratory of Tree Breeding and Cultivation of the State Forestry and Grassland AdministrationResearch Institute of ForestryChinese Academy of ForestryBeijing 100091China Shanghai Key Laboratory of Plant Molecular Sciences College of Life SciencesShanghai Normal UniversityShanghai 200234China College of Horticulture South China Agricultural UniversityGuangzhou 510640China National Center for Gene Research CAS Center for Excellence in Molecular Plant SciencesChinese Academy of SciencesShanghai 200233China

Plant genomics and crop breeding are at the intersection of biotechnology and information *** by a combination of highthroughput sequencing,molecular biology and data science,great advances have been made in omics technologies at every step along the central dogma,especially in genome assembling,genome annotation,epigenomic profiling,and transcriptome *** advances further revolutionized three directions of *** is genetic dissection of complex traits in crops,along with genomic prediction and *** second is comparative genomics and evolution,which open up new opportunities to depict the evolutionary constraints of biological sequences for deleterious variant *** third direction is the development of deep learning approaches for the rational design of biological sequences,especially proteins,for synthetic *** three directions of development serve as the foundation for a new era of crop breeding where agronomic traits are enhanced by genome design.

关键词： bioinformatics plant genomics breeding by design

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Enhanced hydrogen evolution performance by 3D ordered macroporous Ru-CoP@NC electrocatalysts

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Rare Metals 2024年第3期43卷 1095-1107页

作者： chen-chen Zhang Sheng wei Li-Xian Sun Yi-Fang Ouyang Fen Xu hai-Liang Chu Hong-GePan Li-Xin chen Xue-Zhang Xiao School of Material Science and Engineering Guilin University of Electronic TechnologyGuilin541004China School of Chemistry and Chemical Engineering Guangxi UniversityNanning530004China Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhen518055GuangdongChina Institute of Science and Technology for New Energy Xi'an Technological UniversityXi'an710021China School of Materials Science and Engineering Zhejiang UniversityHangzhou310058China

Electrocatalytic water splitting coupled with sustainable energies is identified as an environmentally friendly and renewable strategy to generate high-quality hydrogen for the fuel ***,the main challenge is to develop high performance,low cost and chemically stable electrocatalysts to decline the energy barriers and enhance the sluggish kinetics of hydrogen evolution reaction(HER).Herein,a three-dimensional hierarchically ordered macroporous Ru-CoP@NC electrocatalyst(3DOM Ru-CoP@NC)derived from ordered macro-microporous metal-organic frameworks has been prepared using the precursor@template and double-solvent *** prepared 3DOM Ru-CoP@NC catalyst exhibits an overpotential of 15 mV(j=10 mA·cm^(-2))and a reaction Tafel slope of 38 mV·dec^(-1)in alkaline electrolyte,which are superior to commercial Pt@C ***,the overpotential and reaction Tafel slope of this catalyst in acidic media are 45 mV and 50 mV·dec^(-1),*** outstanding HER activities of 3DOM Ru-CoP@NC catalysts are ascribed to the 3D highly interconnectedreticular nanospaces that can increase effective reaction active *** N dope d carbon framework improves the electronic properties and ***,the strong interaction of Ru and CoP nanoparticles also boosts the HER *** results indicate that 3DOM Ru-CoP@NC catalysts with high catalytic activities have a broad application prospect in the future.

关键词： Hydrogen evolution reaction Template method 3D ordered macroporous Ru-CoP@NC

Biological factors driving colorectal cancer metastasis

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 259-272页

作者： Shuai-Xing An Zhao-Jin Yu chen Fu Min-Jie wei Long-hai Shen Department of Pharmacology School of PharmacyChina Medical UniversityShenyang 110122Liaoning ProvinceChina Liaoning Key Laboratory of Molecular Targeted Antitumor Drug Development and Evaluation Liaoning Cancer Immune Peptide Drug Engineering Technology Research CenterKey Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors(China Medical University)Ministry of EducationShenyang 110122Liaoning ProvinceChina BD Department Greenpine Pharma Group Co.LtdTianjin 300020China Center of Oncology Genertec Liaoyou Gem Flower HospitalPanJin 124010Liaoning ProvinceChina

Approximately 20%of colorectal cancer(CRC)patients present with metastasis at *** Stage I-III CRC patients who undergo surgical resection,18%typically suffer from distal metastasis within the first three years following initial *** median survival duration after the diagnosis of metastatic CRC(mCRC)is only 9 *** is traditionally considered to be an advanced stage malignancy or is thought to be caused by incomplete resection of tumor tissue,allowing cancer cells to spread from primary to distant organs;however,increa-sing evidence suggests that the mCRC process can begin early in tumor *** patients present with high heterogeneity and diverse cancer phenotypes that are classified on the basis of molecular and morphological *** genomic and nongenomic events can induce subclone diversity,which leads to cancer and *** the course of mCRC,metastatic cascades are associated with invasive cancer cell migration through the circulatory system,extravasation,distal seeding,dormancy,and reactivation,with each step requiring specific molecular ***,cancer cells presenting neoantigens can be recognized and eliminated by the immune *** this review,we explain the biological factors that drive CRC metastasis,namely,genomic instability,epigenetic instability,the metastatic cascade,the cancer-immunity cycle,and external lifestyle *** remarkable progress in CRC research,the role of molecular classification in therapeutic intervention remains *** review shows the driving factors of mCRC which may help in identifying potential candidate biomarkers that can improve the diagnosis and early detection of mCRC cases.

关键词： cancer Metastasis cascade Cancer immunity Genomic variation Epigenetic instability Lifestyle factor

Visual test paper based on Au/δ-MnO_(2) hollow nanosphere oxidase-like activity regulation using hexavalent chromium as a smart switch

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Rare Metals 2024年第2期43卷 711-722页

作者： Wen-Chang Zhuang hai-Yue Zhang Zhen-Yang chen Wen-Jing cheng wei-Dan Na Zhao Li Lin Tian School of Materials and Chemical Engineering Xuzhou University of TechnologyXuzhou221018China School of Chemistry and Environmental Science Yili Normal UniversityYining835000China

Paper-based sensing platform is a point of need analytical toolkit for safety ***,the sensitivity,specificity,and simplicity are still ***,we report a novel strategy(Au/δ-MnO_(2) hollow nanosphere and 3,3′,5,5′-tetramethylbenzidine(TMB)induced test strips for signal-on detection)that can be utilized for hexavalent chromium(Cr^(6+))***,Cr^(6+)(CrO_(4)^(2−)) as a smart switch can remarkably enhance the oxidase-like activity of Au/δ-MnO_(2) hollow *** presence of Cr^(6+) can regulate the surface electronic redistribution of Au/δ-MnO_(2) and adjust the geometric configuration,which leads to the improvement in oxidase-like activity of Au/δ-MnO_(2).As a proof-of-concept application,a visual paper-based sensing platform of Cr^(6+) along with quantitative analysis by the test strips was successfully *** paper-based sensing platform exhibits a linear range with excellent selectivity for other interfering substances and lower limit of detection of 0.09μmol·L^(−1),providing a promising toolkit at-home Cr^(6+) measurement and environmental monitoring.

关键词： Point of need Colorimetric biosensing platform Au/δ-MnO_(2) hollow nanosphere Test strip Cr^(6+)

Features and formulae of sediment incipient motion in vegetated flow environment

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Journal of Hydrodynamics 2024年第2期36卷 331-339页

作者： Yu-xuan Xu wei-jie Wang Shi-bao Zhang Han-qing Zhao Xue-kai chen hai-ping Zhang School of Water Conservancy North China University of Water Resources and Electric PowerZhengzhou450045China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing100038China China Three Gorges Corporation Wuhan430010China

Aquatic vegetation is a vital component of natural river ecosystems,playing a crucial role in maintaining ecological balance,providing habitat and improving water ***,the presence of vegetation results in increased resistance in vegetated channels compared with non-vegetated channels,rendering traditional sediment movement predictions inadequate for the ***,the concept of a vegetation influence factor,denoted by CDah,has been proposed by previous researchers to represent the effect of vegetation on sediment movement in *** this study,we focus on exploring the vegetation resistance coefficient(CD)among the vegetation influence factors,evaluating two different calculation methods for vegetation resistance coefficient,and presenting two expressions through genetic algorithm analysis to predict the incipient flow velocity of sediment in vegetated *** predicted values from the new formulae show excellent agreement with measured data,highlighting the high accuracy of the proposed methods in predicting the incipient flow velocity of *** results provide a solid theoretical basis for understanding the influence of aquatic vegetation on sediment particle movement.

关键词： Vegetation flow vegetation resistance coefficient genetic algorithm sediment initiation

A novel profile modification HPF-Co gel satisfied with fractured low permeability reservoirs in high temperature and high salinity

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Petroleum Science 2024年第1期21卷 683-693页

作者： Ya-Kai Li Ji-Rui Hou wei-Peng Wu Ming Qu Tuo Liang wei-Xin Zhong Yu-chen Wen hai-Tong Sun Yi-Nuo Pan China University of Petroleum Beijing Beijing102249China PetroChina Tarim Oilfield Company Korla 841000XinjiangChina Key Laboratory of Improving Oil and Gas Recovery of Ministry of Education Northeast Petroleum University Daqing 163318HeilongjiangChina Xi'an Shiyou University Xi'an 710065ShaanxiChina Northwest Oilfield Company SINOPECUrumqi 830011XinjiangChina

Conformance control and water plugging are a widely used EOR method in mature ***,majority of conformance control and water plugging agents are unavoidable dehydrated situation in high-temperature and high-salinity low permeability ***,a novel conformance control system HPF-Co gel,based on high-temperature stabilizer(CoCl_(2)·H_(2)O,CCH)is *** HPF-Co bulk gel has better performances with high temperature(120℃)and high salinity(1×10^(5)mg/L).According to Sydansk coding system,the gel strength of HPF-Co with CCH is increased to code *** dehydration rate of HPF-Co gel is 32.0%after aging for 150 d at 120℃,showing excellent thermal *** rheological properties of HPF gel and HPF-Co gel are also *** results show that the storage modulus(G′)of HPF-Co gel is always greater than that of HPF *** effect of CCH on the microstructure of the gel is *** results show that the HPF-Co gel with CCH has a denser gel network,and the diameter of the three-dimensional network skeleton is 1.5-3.5μ*** 90 d of aging,HPF-Co gel still has a good three-dimensional *** spectroscopy results show that CCH forms coordination bonds with N and O atoms in the gel amide group,which can suppress the vibration of cross-linked sites and improve the stability at high *** core plugging test determines the optimized polymer gel injection strategy and injection velocity with HPF-Co bulk gel system,plugging rate exceeding 98%.Moreover,the results of subsequent waterflooding recovery can be improved by 17%.

关键词： Low permeability reservoir High-temperature resistant gel Complexation reaction Polymer gel injection strategy Plugging rate Enhanced oil recovery