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Flame quenching process in cavity based on model scramjet combustor

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Acta Mechanica Sinica 2012年第1期28卷 73-78页

作者： Yu Pan Jing Lei Jian-Han Liang wei-dong liu Zhen-Guo Wang Department of Aerospace and Material National University of Defense Technology410073 ChangshaChina

The flame quenching process in combustors was observed by high speed camera and Schlieren system, at the inflow conditions of Ma = 2.64, To = 1483K, P0 = 1.65 MPa, T = 724 K and P -- 76.3 kPa. Changing process of the flame and shock structure in the combustor was clearly observed. The results revealed that the precom- bustion shock disappeared accompanied with the process in which the flame was blown out and withdrawed from the mainflow into the cavity and vanished after a short while. The time of quenching process was extended by the cavity flame holder, and the ability of flame holding was enhanced by arranging more cavities in the downstream as well. The flame was blown from the upstream to the downstream, so the flame in the downstream of the cavity was quenched out later than that in the upstream.

关键词： Flame quenching process Cavity Model scramjet combustor

New insights into the mechanism of surfactant enhanced oil recovery:Micellar solubilization and in-situ emulsification

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Petroleum Science 2022年第2期19卷 870-881页

作者： Xue-Zhi Zhao Guang-Zhi Liao Ling-Yan Gong Huo-Xin Luan Quan-Sheng Chen wei-dong liu dong liu Yu-Jun Feng Polymer Research Institute State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065People's Republic of China PetroChina Exploration&Production Company Beijing100007People's Republic of China Research Institute of Experiment and Detection Xinjiang Oilfield Branch CompanyPetroChinaKaramay834000People's Republic of China Research Institute of Petroleum Exploration&Development PetroChina Company LimitedBeijing100083People's Republic of China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang621000People's Republic of China

Reducing the oil-water interfacial tension(IFT)to ultra-low is believed the primary mechanism for surfactant-based enhanced oil recovery(EOR)***,field trials have shown that low concentration surfactant flooding can also improve oil recovery without ultra-low *** clarify the mechanism behind,the currently-used surfactant,naphthenic arylsulfonate(NAS),was used to unravel its function during surfactant flooding from the horizon of micron-and *** solubilization capacity of NAS micelle to petroleum fractions was evaluated through light absorbance strategy,smallangle neutron scattering,dynamic light scattering and transmission electron *** was found that micellar solubilization plays a significant role during the surfactant ***-situ emulsification was visualized in microfluidics with three types of microchips,respectively.A series of displacement tests were carried out with NAS solution pumping into oil-saturated *** results show that in-situ emulsification improve oil recovery mainly through blocking and entrainment *** from this work aid in understanding the interaction between surfactant solution and petroleum fractions at low surfactant concentration,which is helpful for design surfactant-based displacing system for EOR process.

关键词： Enhanced oil recovery Surfactant flooding Micellar solubilization Microfluidics In-situ emulsification

Experimental investigation of combustion mechanisms of kerosene-fueled scramjet engines with double-cavity flameholders

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Acta Mechanica Sinica 2011年第6期27卷 891-897页

作者： Yu Pan Jian-Guo Tan Jian-Han Liang wei-dong liu Zhen-Guo Wang Department of Aerospace and Material National University of Defense and Technology 410073 Changsha China

A scramjet combustor with double cavitybased flameholders was experimentally studied in a directconnected test bed with the inflow conditions of M = 2.64,Pt = 1.84 MPa,Tt = 1 300 *** ignition and selfsustained combustion with room temperature kerosene was achieved using pilot hydrogen,and kerosene was vertically injected into the combustor through 4×φ 0.5 mm holes mounted on the *** different equivalence ratios and different injection schemes with both tandem cavities and parallel cavities,flow fields were obtained and compared using a high speed camera and a Schlieren *** revealed that the combustor inside the flow field was greatly influenced by the cavity installation scheme,cavities in tandem easily to form a single side flame distribution,and cavities in parallel are more likely to form a joint flame,forming a choked combustion *** supersonic combustion flame was a kind of diffusion flame and there were two kinds of combustion *** the unchoked combustion mode,both subsonic and supersonic combustion regions *** in the choked mode,the combustion region was fully subsonic with strong shock propagating *** also showed that there was a balance point between the boundary separation and shock enhanced combustion,depending on the intensity of heat release.

关键词： Scramjet. Supersonic combustion. Flame structure Cavity flameholder

Convergence Rates of Tail Probabilities for Sums under Dependence Assumptions

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Acta Mathematica Sinica,English Series 2010年第8期26卷 1591-1600页

作者： Xiao Rong YANG wei dong liu Ke Ang FU Lin Xin ZHANG School of Statistics and Mathematics Zhejiang Gongshang University Hangzhou 310018 P. R. China Department of Mathematics Zhejiang University Hangzhou 310027 P. R. China School of Statistics and Mathematics Zhejiang Gongshang University Han qzhou 310018 P. R. China

Let {X,X1,X2,……}be a zero mean strictly stationary Ф-mixing sequence. Set Sn=∑n k=1 and f（x^p）=∑∞n=1 n^r-2P（｜Sn｜≥x^p√ES2nlog n）,When ε〉（√2）1/p,for p〉1/2 and r〉1,the conditions for ∫∞ε f（x^p）dx 〈∞ to hold is established, by using coupled methods together withstrong approximation, which are different from the traditional symmetrization and Hoffman-JФrgensen inequality.

关键词： Complete convergence mixing sequences strong approximation

Down-regulation of Risa improves podocyte injury by enhancing autophagy in diabetic nephropathy

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Military Medical Research 2023年第1期10卷 32-44页

作者： Pei-Pei Su dong-wei liu Si-Jie Zhou Hang Chen Xian-Ming Wu Zhang-Suo liu Department of Nephrology the First Affiliated Hospital of Zhengzhou UniversityResearch Institutes of NephropathyZhengzhou UniversityZhengzhou 450052China Department of Nephrology and Rheumatology the Third People’s Hospital of ZhengzhouZhengzhou 450002China Henan Province Research Center for Kidney Disease Zhengzhou 450052China Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province Zhengzhou 450002China

Background: LncRNA AK044604(regulator of insulin sensitivity and autophagy, Risa) and autophagy-related factors Sirt1 and GSK3β play important roles in diabetic nephropathy(DN). In this study, we sought to explore the effect of Risa on Sirt1/GSK3β-induced podocyte ***: Diabetic db/db mice received Risa-inhibition adeno-associated virus(AAV) via tail vein injection, and intraperitoneal injection of lithium chloride(LiCl). Blood, urine, and kidney tissue samples were collected and analyzed at different time points. Immortalized mouse podocyte cells(MPCs) were cultured and treated with Risa-inhibition lentivirus(LV), EX-527, and LiCl. MPCs were collected under different stimulations as noted. The effects of Risa on podocyte autophagy were examined by qRT-PCR, Western blotting analysis, transmission electron microscopy,Periodic Acid-Schiff staining, and immunofluorescence ***: Risa and activated GSK3β were overexpressed, but Sirt1 was downregulated in DN mice and high glucosetreated MPCs(P<0.001, db/m vs. db/db, NG or HM vs. HG), which was correlated with poor prognosis. Risa overexpression attenuated Sirt1-mediated downstream autophagy levels and aggravated podocyte injury by inhibiting the expression of Sirt1(P<0.001, db/m vs. db/db, NG or HM vs. HG). In contrast, Risa suppression enhanced Sirt1-induced autophagy and attenuated podocyte injury, which could be abrogated by EX-527(P<0.001, db/db+Risa-AAV vs. db/db, HG+Risa-LV vs. HG). Furthermore, LiCl treatment could restore GSK3β-mediated autophagy of podocytes(P<0.001, db/db+LiCl vs. db/db, HG+LiCl vs. HG), suggesting that Risa overexpression aggravated podocyte injury by decreasing ***: Risa could inhibit autophagy by regulating the Sirt1/GSK3β axis, thereby aggravating podocyte injury in DN. Risa may serve as a therapeutic target for the treatment of DN.

关键词： Diabetic nephropathy LncRNA AK044604/Sirt1/GSK3β Autophagy

Eradication of H pylori infection in a rural population: One-day quadruple therapy versus 7-day triple therapy

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World Journal of Gastroenterology 2006年第24期12卷 3915-3918页

作者： Lian Zhang Lin Shen Jun-Ling Ma Kai-Feng Pan wei-dong liu Jie Li Shu-dong Xiao San-Ren Lin Meinhard Classen wei-Cheng You Department of Cancer Epidemiology Peking University School of Oncology Beijing Cancer Hospital and Institute Beijing 100036 China Department of Internal Medicine PekingUniversity School of Oncology Beijing Cancer Hospital and Institute Beijing 100036 China Linqu Public Health Bureau Linqu Shandong 262600 China Shanghai Institute for Digestive Disease Shanghai China The Third Hospital of Peking University Beijing China Technical University Munich Germany

AIM： To compare the one-day quadruple therapy with a standard 7-d triple therapy for H pylori eradication in a rural population of China. METHODS： A total of 396 patients with 13C-urea breath test positive for H pylori were assigned into two groups： 239 patients received one-day quadruple therapy （amoxicillin 2000 mg qid; metronidazole 500 mg qid; bismuth citrate 900 mg qid and lansoprazole 60 mg once daily） and 157 patients received 7-d standard triple therapy （amoxicillin 1000 mg bid; clarithromycin 500 mg bid and lansoprazole 30 mg bid）. All the patients underwent a 13C-UBT to assess the eradication of Hpylori infection six weeks after treatment. RESULTS： Two hundred and twenty-nine patients completed the one-day therapy （95.8%） and 148 patients completed the 7-d therapy （94.2%）. The oneday therapy eradicated H pylori infection in 64 patients （27.95%）. In contrast, 103 patients （69.59%） were Hpylori negative after the 7-d therapy （P 〈 0.01）. CONCLUSION： This pilot study suggests there is no beneficial effect of the one-day therapy in treatment ofHpylori infection compared with the 7-d standard therapy.

关键词： Eradication H pylori infection Quadrupletherapy Triple therapy

Numerical study on ethylene-air continuous rotating detonation in annular combustors with different widths

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2022年第5期23卷 388-404页

作者： wei-jie FAN wei-dong liu Hao-yang PENG Shi-jie liu Jian SUN Science and Technology on Scramjet Laboratory College of Aerospace Science and TechnologyNational University of Defense TechnologyChangsha 410073China State Key Laboratory of Aerospace Dynamic Satellite Control CenterXi’an 710043China

To investigate the impact of combustor width on continuous rotating detonation(CRD)fueled by ethylene and air,a series of 3 D simulations are conducted by changing the inner cylinder radius of an annular combustor while retaining the same outer cylinder *** results show that the CRD wave propagates more steadily and faster as the combustor width *** high-temperature zone at the backward-facing step preheats the propellants and contributes to the steady propagation of the CRD wave in 25-and 30-mm wide *** highest and the lowest velocities are obtained in the30-and 15-mm wide combustors at,respectively,1880.27 and 1681.01 m/*** the other hand,the average thrust decreases as the combustor width *** highest thrust is obtained in the 15-mm wide combustor while the lowest is in the 30-mm wide combustor,at 758.06 and 525.93 N,***,the thrust is much more stable in the 25-and 30-mm wide combustors than in the 15-and 20-mm wide combustors.

关键词： Continuous rotating detonation(CRD) Ethylene-air Combustor width Propagation mode Propulsive performance

Combined molybdenum target X-ray and magnetic resonance imaging examinations improve breast cancer diagnostic efficacy

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World Journal of Clinical Cases 2022年第2期10卷 485-491页

作者： Wen-Quan Gu Sun-Mei Cai wei-dong liu Qi Zhang Ying Shi Li-Juan Du Department of Radiology Punan HospitalShanghai 200126China

BACKGROUND Early-stage breast cancer patients often lack specific clinical manifestations,making diagnosis *** target X-ray and magnetic resonance imaging(MRI)examinations both have their own ***,a combined examination methodology may improve early breast cancer *** To explore the combined diagnostic efficacy of molybdenum target X-ray and MRI examinations in breast *** Patients diagnosed with breast cancer at our hospital from March 2019 to April 2021 were recruited,as were the same number of patients during the same period with benign breast *** groups underwent molybdenum target X-ray and MRI examinations,and diagnoses were given based on each *** single(i.e.,X-ray or MRI)and combined(i.e.,using both methods)diagnoses were counted,and the MRI-related examination parameters(e.g.,T-wave peak,peak and early enhancement rates,and apparent diffusion coefficient)were compared between the *** In total,63 breast cancer patients and 63 benign breast tumor patients were *** detected 53 breast cancer cases and 61 benign breast tumor *** target X-ray detected 50 breast cancer cases and 60 benign breast tumor *** combined methodology detected 61 breast cancer cases and 61 benign breast tumor *** sensitivity(96.83%)and accuracy(96.83%)of the combined methodology were higher than single-method MRI(84.13%and 90.48%,respectively)and molybdenum target X-ray(79.37%and 87.30%,respectively)(P0.05).The Twave peak(169.43±32.05)and apparent diffusion coefficient(1.01±0.23)were lower in the breast cancer group than in the benign tumor group(228.86±46.51 and 1.41±0.35,respectively).However,the peak enhancement rate(1.08±0.24)and early enhancement rate(1.07±0.26)were significantly higher in the breast cancer group than in the benign tumor group(0.83±0.1

关键词： Molybdenum X-rays Magnetic resonance imaging Breast neoplasms Early diagnosis Radiology

MicroRNA-184 promotes proliferation ability of glioma cells by regulating FOXO3

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Asian Pacific Journal of Tropical Medicine 2014年第10期7卷 776-779页

作者： Qing-Ke Cui wei-dong liu Jian-Xin Zhu Yun-Hua Wang Zhi-Gang Wang Department of Neurosurgery The Qilu Hospital of Shandong University Liaocheng People's Hospital

Objective:To investigate the effect of microRNA(miR-184)on regulating the *** and prolifration of glioma ***:Lipidosome was used to transfect miR-184 mimic and inhibitor to glioma cell ling,and the cell proliferation ability changes were determined by MTT and plate cloning experiment after the *** test was used to measure the levels of cyclinD1,p27 and *** was used to detect miR-184expression in glioma cell *** tissues and adjacent *** experiment was used to test 3'UTR gene targeting regulation of miR-184 and ***:QPCR results showed a significaat lower miR-184 expression level in glioma cell line and glioma tissues than that in juxtacancerous *** and plate cloning experiments have shown that after overexpressing of miR-184,the cell proliferation capacity of glioma U87 and T98G was signifieantly increased,which was significantly inhibited after the inhibition of *** results showed a lower expression level of p27 in U87 and T98G cells,and a higher expression level of cyclind1after over-expressing of miR-184 wss ***.a lower expression level of eyelinD1and a higher expression level of p27 after the inhibition of *** luciferase activity was inhibited after the over-expressing of ***:MiR-184 can affect the proliferation abilities of glioma cells and regulate the cell cycle related *** plays an important role in the occurrence and development of gliomas.

关键词： miR-184 Glioma Cell proliferation FOXO3