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四川盆地“槽-隆”控制下的寒武系筇竹寺组页岩储层特征及其差异性成因

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石油与天然气地质 2024年第2期45卷 420-439页

作者：何骁郑马嘉刘勇赵群石学文姜振学吴伟伍亚宁诗坦唐相路刘达东中国石油西南油气田分公司四川成都610051 中国石油西南油气田分公司开发事业部四川成都610051 中国石油勘探开发研究院北京100083 中国石油西南油气田分公司页岩气研究院四川成都610051 中国石油大学(北京)油气资源与工程全国重点实验室北京102249

四川盆地寒武系筇竹寺组是继五峰组-龙马溪组后页岩气勘探开发的重要接替层位,目前在德阳-安岳裂陷槽中心和槽缘部署的Z201井和WY1井页岩气勘探取得良好效果,但裂陷槽内筇竹寺组页岩储层发育特征仍不清楚。以槽内中心Z201井和槽缘WY1井... 详细信息

四川盆地寒武系筇竹寺组是继五峰组-龙马溪组后页岩气勘探开发的重要接替层位,目前在德阳-安岳裂陷槽中心和槽缘部署的Z201井和WY1井页岩气勘探取得良好效果,但裂陷槽内筇竹寺组页岩储层发育特征仍不清楚。以槽内中心Z201井和槽缘WY1井为重点,结合其他页岩气勘探开发资料,系统分析了研究区筇竹寺组页岩各小层矿物特征、有机地化特征、储层及储集空间特征、含气性特征。研究结果表明:①筇竹寺组可划分为8个小层,页岩整体以脆性矿物为主,总有机碳含量(TOC)普遍大于1%,为优质烃源岩,且槽内TOC高于槽缘,具备良好的生气条件。②筇竹寺组页岩有机孔与无机孔均发育,槽内孔隙发育更好,具有极高的含气量。1,3,5和7小层黑色页岩储层品质较好,5小层储层品质最优。③德阳-安岳裂陷槽控制了筇竹寺组页岩储层发育,槽内Z201井钻遇的筇竹寺组页岩储层优于槽缘WY1井。④乐山-龙女寺古隆起控制筇竹寺组页岩有机质演化程度,古隆起内筇竹寺组有机质热演化成熟度普遍低于古隆起外,隆起区适中的热演化程度具备大规模富气的条件。筇竹寺组页岩储层各项条件较好,是未来页岩气勘探开发的主要接替区域。

关键词：德阳-安岳裂陷槽乐山-龙女寺古隆起储层特征页岩气筇竹寺组寒武系四川盆地

A Computer-Aided System for Ocular Myasthenia Gravis Diagnosis

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Tsinghua Science and Technology 2021年第5期26卷 749-758页

作者： Guanjie Liu Yan wei Yunshen Xie Jianqiang Li Liyan Qiao Ji-jiang Yang the Faculty of Information Technology Beijing University of TechnologyBeijing 100124China the Neurology Department The Second Affiliated Hospital of Tsinghua UniversityBeijing 100040China the Department of Automation Tsinghua UniversityBeijing 100084China

The current mode of clinical aided diagnosis of Ocular Myasthenia Gravis(OMG)is time-consuming and laborious,and it lacks quantitative *** aided diagnostic system for OMG is proposed to solve this *** values calculated by the system include three clinical indicators:eyelid distance,sclera distance,and palpebra superior fatigability test *** the first two indicators,the semantic segmentation method was used to extract the pathological features of the patient's eye image and a semantic segmentation model was *** patient eye image was divided into three regions:iris,sclera,and *** indicators were calculated based on the position of the pixels in the segmentation *** the last indicator,a calculation method based on the Eyelid Aspect Ratio(EAR)is proposed;this method can better reflect the change of eyelid distance over *** system was evaluated based on the collected patient *** results show that the segmentation model achieves a mean Intersection-Over-Union(mIoU)value of 86.05%.The paired-sample T-test was used to compare the results obtained by the system and doctors,and the p values were all greater than ***,the system can reduce the cost of clinical diagnosis and has high application value.

关键词： ocular myasthenia gravis computer-aided system semantic segmentation eyelid aspect ratio

CO耐受的单位点/纳米颗粒协同型质子交换膜燃料电池阳极催化剂

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Science Bulletin 2024年第8期69卷 1061-1070页

作者：王显杨小龙王颖梅丙宝金钊李阳施兆平姜政刘长鹏邢巍葛君杰 State Key Laboratory of Electroanalytic Chemistry Jilin Province Key Laboratory of Low Carbon Chemistry PowerInstitution Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201204China Shanghai Synchrotron Radiation Facility Zhangjiang National LabShanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China University of Chinese Academy of Sciences Beijing 100049China

Nanosized Pt catalysts are the catalyst-of-choice for proton exchange membrane fuel cell(PEMFC)anode,but are limited by their extreme sensitivity to CO in parts per million(ppm)level,thereby making the use of ultrapure H_(2)a prerequisite to ensure acceptable ***,we confront the CO poisoning issue by bringing the Ir/Rh single atom sites to synergistically working with their metallic *** presence of 1000 ppm CO,the catalyst represents not only undisturbed H_(2)oxidation reaction(HOR)catalytic behavior in electrochemical cell,but also unparalleled peak power density at 643 mW cm^(-2)in single cell,27-fold in mass activity of the best PtRu/C catalysts ***-poisoning experiments and surface-enhanced Raman scattering spectroscopy(SERS)and calculation results in combine suggest the presence of adjacent Ir/Rh single atom sites(SASs)to the nanoparticles(NPs)as the origin for this prominent catalytic *** single sites not only exhibit superb CO oxidation performance by themselves,but can also scavenge the CO adsorbed on approximated NPs via supplying reactive OH**** open up a new route here to conquer the formidable CO poisoning issue through single atom and nanoparticle synergistic catalysis,and pave the way towards a more robust PEMFC future.

关键词： CO-tolerant anode catalyst Fuel cells Dual metal catalysts Bifunctional catalyst

Application of germ-free NOD-scid IL2rg^(null)mice as a humanized model for tumor microbiome precision medicine

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Science China(Life Sciences) 2021年第4期64卷 644-647页

作者： Chengwei Wu Haitao Shang Xianhong jiang Xinning Wang Hong wei Precision Medicine Instiute The First Afiliated HospitalSun Ya-sen UniversityGuangzhou 510080China College of Animal Sciences and Technology Slate Key Laboratory of Agricultural MicrobiologyHuazhong Agriculnural UniversityWuhan 430070China

In 2013,tumor immunotherapy topped the list of the top ten scientific breakthroughs(Couzin-Frankel,2013),and it was widely used in the treatment of lung cancer,kidney cancer,and melanoma(Routy et al.,2018).However,the response rate of patients to tumor immunotherapy varies,and usually,only a small percentage of patients respond well to treatment(Sambi et al.,2019).

关键词： al. lung cancer

On the designing principles and optimization approaches of bio-inspired self-organized network: a survey

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Science China(Information Sciences) 2013年第7期56卷 5-32页

作者： ZHANG zhongShan HUANGFU wei LONG KePing ZHANG Xu LIU XiaoYuan zhong Bin Institute of Advanced Network Technology and New Services (ANTS) University of Science and Technology Beijing (USTB) Beijing Engineering and Technology Center for Convergence Networks and Ubiquitous Services University of Science and Technology Beijing (USTB)

A plethora of studies on self-organization has been carried out in broad areas including chemistry, biology, astronomy, medical science, telecommunications, etc., in both academia and industry. Following the studies on swarm intelligence observed in social species, the artificial self-organized systems are expected to exhibit some intelligent features (e.g., flexibility, robustness, decentralized control, self-evolution, etc.) that may have made social species so successful in the biosphere. In this paper, the application of swarm intelligence in communications networks will be studied, and we survey different aspects of bio-inspired mechanisms and examine various algorithms that have been proposed to improve the performance of artificial systems. Some fundamental self-organized networking (SON) mechanisms, designing principles and optimization approaches for artificial systems will then be investigated, followed by some well-known bio-inspired algorithms (e.g., cooperation, division of labor, distributed network synchronization, load balancing, etc.) as well as their applications to the maintenance/operation/optimization of artificial systems being analyzed. Besides, some new emerging technologies, such as the Self-X capabilities and cognitive machine-to-machine (M2M) optimization for the 3rd Generation Partnership Project (3GPP) Long Term Evolution (LTE)/LTE-Advanced systems, are also surveyed. Finally, the remaining challenges to be faced in designing the future heterogeneous systems will be discussed.

关键词： self-organized networking heterogeneous cognitive radio bio-inspired swarm intelligence decentralized load balancing cooperation

The gut microbiome and intestinal failure-associated liver disease

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国际肝胆胰疾病杂志:英文版 2023年第5期22卷 452-457页

作者： Lu jiang Juan Xu Si-Yang Cheng Ying Wang wei Cai Division of Pediatric Gastroenterology and Nutrition Xinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200092China Shanghai Institute for Pediatric Research Shanghai 200092China Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition Shanghai 200092China Department of Pediatric Surgery Xinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200092China

Intestinal failure-associated liver disease(IFALD)is a common hepatobiliary complication resulting from long-term parenteral nutrition(PN)in patients with intestinal *** spectrum of IFALD ranges from cholestasis,steatosis,portal fibrosis,to *** of IFALD is a multifactorial process,in which gut dysbiosis plays a critical role in its initiation and progression in conjunction with increased intestinal permeability,activation of hepatic immune responses,and administration of lipid *** microbiota manipulation including pre/probiotics,fecal microbiota transplantation,and antibiotics has been studied in IFALD with varying *** this review,we summarize current knowledge on the taxonomic and functional changes of gut microbiota in preclinical and clinical studies of *** also review the function of microbial metabolites and associated signalings in the context of *** providing microbiota-targeted interventions aiming to optimize PN-induced liver injury,our review provides perspectives for future basic and translational investigations in the field.

关键词： Parenteral nutrition Microbiota Bile acid Short-chain fatty acid Prebiotics Probiotics

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新疆冬小麦籽粒品质性状遗传差异与关联分析

作物学报 2024年第6期50卷 1394-1405页

作者：马艳明娄鸿耀王威孙娜颜国荣张胜军刘杰倪中福徐麟新疆农业科学院农作物品种资源研究所新疆乌鲁木齐830091 中国农业大学农学院北京100193 北京市农林科学院杂交小麦研究所北京100097 新疆伊犁哈萨克自治州农业科学研究所新疆伊宁835011

小麦籽粒品质与面粉加工的食品品质密切相关,是小麦早期品质选择的重要依据。本研究以产自新疆的134个冬小麦地方品种和54个育成品种为材料,对连续2年种植收获于新疆乌鲁木齐市、新疆伊宁市共计4个试验点的小麦籽粒进行品质检测与全基... 详细信息

小麦籽粒品质与面粉加工的食品品质密切相关,是小麦早期品质选择的重要依据。本研究以产自新疆的134个冬小麦地方品种和54个育成品种为材料,对连续2年种植收获于新疆乌鲁木齐市、新疆伊宁市共计4个试验点的小麦籽粒进行品质检测与全基因组关联分析。结果表明,7个小麦籽粒品质性状的广义遗传力在62.14%~85.35%之间,由大到小排序依次为:硬度(85.35%)>湿面筋含量(78.44%)>出粉率(73.13%)>容重(72.50%)>沉降值(66.70%)>籽粒蛋白质含量(65.24%)>淀粉含量(62.14%)。在4个不同环境下,7个小麦籽粒品质性状表现为蛋白质含量、湿面筋含量、沉降值的变异相对较大,籽粒硬度的变异居中,淀粉含量、出粉率、容重的变异较小,多数籽粒品质性状间呈极显著相关性。设定阈值P<0.01,经关联分析,7个性状共检测到6605个显著性SNP标记,可解释6.021%~31.467%的变异。4个环境下检测到2个以上性状共有的多性状位点12个,可以解释6.233%~17.708%的表型变异。分别是蛋白质含量/沉降值、蛋白质含量/容重共有位点各1个,分别位于6A、2B上;蛋白质含量/湿面筋含量共有位点5个,分别位于3A、1B、6B、7B和7D上;沉降值/容重/籽粒硬度3个性状共有位点1个,位于5B上;蛋白质含量/沉降值/湿面筋含量3个性状共有位点3个,位于7A、3B和2D上,蛋白质含量/沉降值/湿面筋含量/容重4个性状共有位点1个,染色体位置未知。筛选出11个多性状、多环境品质相关基因,其中TraesCS6B01G347500编码一种储运蛋白,TraesCS1B01G395400编码碳水化合物转运蛋白/糖转运蛋白,TraesCS2D01G246500基因编码具有耐冷、耐盐、节水相关的蛋白ESKIMO1,可作为候选基因进行等位变异分析和标记开发,为小麦标记辅助选择育种提供分子工具。

关键词：新疆冬小麦籽粒品质遗传差异关联分析

Composition and structure of coatings on Ti-6Al-4V alloy by micro-plasma oxidation in NaAlO2 solution

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中国有色金属学会会刊：英文版 2004年第Z1期14卷 162-165页

作者： YAO zhong-ping jiang Zhao-hua SUN Xue-tong WU Zheng-dong ZHANG Xue-lin Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China

Compound ceramic coatings on Ti-6Al-4V alloy were prepared for different time by pulsed bi-polar micro-plasma oxidation (MPO) in NaAlO2 solution. The phase composition was studied by XRD. And the electrochemical impedance spectra (EIS) of the coatings were measured to study the structure of the coatings, combined with the surface morphology. Using the proper EIS interpreting software, the "equivalent circuit" of the coatings was established, and meanwhile fitting values of equivalent element were obtained. The results show that the coating is composed of Al2 TiO5, α-Al2O3 and rutile TiO2, of which Al2 TiO5 is the main crystalline. Increasing the MPO time, the contents of Al2TiO5, rutile TiO2 and α-Al2O3 in the surface of the coating increase. And the EIS analysis and the surface morphology of the coatings illustrates the double-layer structure of the coatings, and the outer layer is loosen and the inner layer is compact. With the increase of the oxidizing time, the surface coarse degree of the coatings and the porosity of the outer layer of the coating are increased while the compactness of the inner layer of the coating is improved.

关键词： micro-plasma oxidation ceramic coatings electrochemical impedance spectra Ti-6Al-4V alloy

Application of machine learning algorithms for the evaluation of seismic soil liquefaction potential

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Frontiers of Structural and Civil Engineering 2021年第2期15卷 490-505页

作者： Mahmood AHMAD Xiao-wei TANG jiang-Nan QIU Feezan AHMA Wen-Jing GU State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China Department of Civil Engineering University of Engineering and Technology Peshawar(Bannu Campus)Bannu 28100Pakistan School of Economics&Management Dalian University of TechnologyDalian 116024China Department of Civil Engineering Abasyn UniversityPeshawar 25000Pakistan

This study investigates the performance of four machine learning(ML)algorithms to evaluate the earthquake-induced liquefaction potential of soil based on the cone penetration test field case history records using the Bayesian belief network(BBN)learning software *** BBN structures that were developed by ML algorithms-K2,hill climbing(HC),tree augmented naive(TAN)Bayes,and Tabu search were adopted to perform parameter learning in Netica,thereby fixing the BBN *** performance measure indexes,namely,overall accuracy(OA),precision,recall,F-measure,and area under the receiver operating characteristic curve,were used to evaluate the training and testing BBN models’performance and highlight the capability of the K2 and TAN Bayes models over the Tabu search and HC *** sensitivity analysis results showed that the cone tip resistance and vertical effective stress are the most sensitive factors,whereas the mean grain size is the least sensitive factor in the prediction of seismic soil liquefaction *** results of this study can provide theoretical support for researchers in selecting appropriate ML algorithms and improving the predictive performance of seismic soil liquefaction potential models.

关键词： seismic soil liquefaction Bayesian belief network cone penetration test parameter learning structural learning