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Nanodiamond/Ti_(3)C_(2) MXene-coated quartz crystal microbalance humidity sensor with high sensitivity and high quality factor

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Rare Metals 2024年第6期43卷 2719-2729页

作者： Yao Yao Qiao Chen Yan-Qi Li Xian-He Huang wei-wei ling Zhe-MiaoXie Jia-QiWang Chang-Ming Chen College of Communication Engineering Chengdu University of Information TechnologyChengdu 610225China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Advanced Micro-/Nano-Devices Lab Department of Systems Design EngineeringUniversity of WaterlooWaterlooON N2L 3GlCanada

To address the challenge of achieving both high sensitivity and a high quality factor in quartz crystal microbalance(QCM)humidity sensors,a nanodiamond(ND)/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was *** material characteristics of ND,Ti_(3)C_(2)MXene,and ND/Ti_(3)C_(2)MXene composite were analyzed by transmission electron microscopy(TEM)and Fourier transform infrared(FTIR)*** experimental results demonstrated that the hydrophilic ND nanoparticles coated on Ti_(3)C_(2) MXene nanosheet prevented the self-stacking of Ti_(3)C_(2)MXene and enhanced the sensitivity of Ti_(3)C_(2) MXene-based QCM humidity ***,the high mechanical modulus of Ti_(3)C_(2) MXene material helped ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor to achieve a high quality factor(>20,000).ND/Ti_(3)C_(2)MXene compositecoated QCM humidity sensor exhibited a sensitivity of 82.45 Hz/%RH,a humidity hysteresis of 1.1%RH,fast response/recovery times,acceptable repeatability,and good stability from 11.3%RH to 97.3%*** response mechanism of ND/Ti_(3)C_(2) MXene composite-coated QCM humidity sensor was analyzed in combination with a bi-exponential kinetic adsorption ***,the potential application of ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was demonstrated through its frequency response to wooden blocks with different moisture contents.

关键词： Humidity sensor Quartz crystal microbalance Nanodiamond Ti_(3)C_(2)MXene High quality factor

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Robust Tomlinsion-Harashima precoding design with outdated CSIT

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The Journal of China Universities of Posts and Telecommunications 2010年第2期17卷 59-62页

作者： WANG Xu-zhen ,NIU Kai,HE Zhi-qiang,YU Guang-wei,WU wei-ling Key Laboratory of Universal Wireless Communications,Ministry of Education,Beijing University of Posts and Telecommunications,Beijing 100876,China [a] Key Laboratory of Universal Wireless Communications Ministry of Education Beijing University of Posts Telecommunications Beijing 100876 China

The channel state information at transmitter （CSIT） acquisition plays a key role in the multi-input multi-output （MIMO） system, especially for the precoding schemes. However it is unrealizable to acquire perfect CSIT in practice. In this article, an effective and practical dynamic CSIT model is introduced to acquire imperfect channel state information. For practicability, the channel temporal and spatial correlations are considered and the channel estimate and its error covariance are obtained by utilizing the outdated channel state information. Based on the dynamic CSIT mode, closed-form solution of robust Tomlinsion-Harashima precoding （THP） is derived by a Lagrangian approach. Numerical simulations are presented to demonstrate the performance.

关键词： channel estimation imperfect CSIT robust THP

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Maternal zinc deficiency impairs brain nestin expression in prenatal and postnatal mice

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Cell Research 2001年第2期11卷 135-141页

作者： WANG FU DI, wei BIAN, ling wei KONG, FA JI ZHAO, JUN SHENG GUO, NAI HE JINGI Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China Department of Publ 2Department of Public Health Second Military Medical University Shanghai 200433 China 1Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 320 Yue Yang Road Shanghai 200031 China 1Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 320 Yue Yang Road Shanghai 200031 China 2Department of Public Health Second Military Medical University Shanghai 200433 China 2Department of Public Health Second Military Medical University Shanghai 200433 China 1Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 320 Yue Yang Road Shanghai 200031 China

Effects of maternal dietary zinc deficiency on prenatal and postnatal brain development were investigated in ICR strain mice. From d 1 of pregnancy (EO) until postnatal d 20 (P20), maternal mice were fed experimental diets that contained 1 mg Zn/kg/day (severe zinc deficient, SZD), 5 mg Zn/kg/day (marginal zinc deficient, MZD), 30 mg Zn/kg/day (zinc adequately supplied, ZA) or 100 mg Zn/kg/day (zinc supplemented, ZS and pair-fed, PF). Brains of offspring from these dietary groups were examined at various developmental stages for expression of nestin, an intermediate filament protein found in neural stem cells and young neurons. Immunocytochemistry showed nestin expression in neural tube 10. 5 d post citrus (dpc) as well as in the cerebral cortex and neural tube from 10.5 dpc to postnatal d 10 (P10). Nestin immunoreactivities in both brain and neural tube of those zinc-supplemented control groups (ZA, ZS, PF) were stronger than those in zinc-deficient groups (SZD and MZD). Western blot analysis confirmed that nestin levels in -pooled brain extracts from each of the zinc-supplemented groups (ZA, ZS, PF) were much higher than those from the zinc-deficient groups (SZD and MZD) from 10.5 dpc to P10. Immunostaining and Western blots showed no detectable nestin in any of the experimental and control group brains after P20. These observations of an association between maternal zinc deficiency and decreased nestin protein levels in brains of offspring suggest that zinc deficiency suppresses development of neural stem cells, an effect which may lead to neuroanatomical and behavioral abnormalities in adults.

关键词： Zinc deficiency nestin brain development neural stem cells.

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Acute and chronic excitotoxicity in ischemic stroke and late-onset Alzheimer's disease

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Neural Regeneration Research 2025年第7期20卷 1981-1988页

作者： Shan Ping Yu Emily Choi Michael QJiang ling wei Department of Anesthesiology Emory University School of MedicineAtlantaGAUSA Center for Visual and Neurocognitive Rehabilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke and Alzheimer's disease are common neurological disorders and often occur in the same *** comorbidity of the two neurological disorders represents a grave health threat to older *** review presents a brief background of the development of novel concepts and their clinical *** activity of glutamatergic N-methyl-D-aspartate receptors and N-methyl-D-aspartate receptor-mediated Ca^(2+)influx is critical for neuronal *** ischemic insult induces prompt and excessive glutamate release and drastic increases of intracellular Ca^(2+)mainly via N-methyl-D-aspartate receptors,particularly of those at the extrasynaptic *** Ca^(2+)-evoked neuronal cell death in the ischemic core is dominated by necrosis within a few hours and days known as acute ***,mild but sustained Ca^(2+)increases under neurodegenerative conditions such as in the distant penumbra of the ischemic brain and early stages of Alzheimer's disease are not immediately toxic,but gradually set off deteriorating Ca^(2+)-dependent signals and neuronal cell loss mostly because of activation of programmed cell death *** on the Ca^(2+)hypothesis of Alzheimer's disease and recent advances,this Ca^(2+)-activated“silent”degenerative excitotoxicity evolves from years to decades and is recognized as a unique slow and chronic *** N-methyl-D-aspartate receptor subunit GluN3A,primarily at the extrasynaptic site,serves as a gatekeeper for the N-methyl-D-aspartate receptor activity and is neuroprotective against both acute and chronic *** stroke and Alzheimer's disease,therefore,share an N-methyl-D-aspartate receptor-and Ca^(2+)-mediated mechanism,although with much different time *** is thus proposed that early interventions to control Ca^(2+)homeostasis at the preclinical stage are pivotal for individuals who are susceptible to sporadic late-onset Alzheimer's disease and Alzheimer's disease-related

关键词： Ca^(2+)hypothesis cognitive deficits hyperactivity late-onset Alzheimer's disease neurodegeneration N-methyl-D-aspartate receptors N-methyl-D-aspartate receptor subunits pathogenesis preventive treatment

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Characterization of Hepatic Drug-metabolizing Activities of Bama Miniature Pigs (Sus Scrofa Domestica): Comparison with Human Enzyme Analogs

Characterization of Hepatic Drug-metabolizing Activities of ...

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中国实验动物学会第七届学术年会

作者： Jian Li, Yong Liu, Jiang-wei Zhang, Hong wei, and ling Yang

We used various substrates and selective inhibitors of human cytochrome P450 (CYP) isozymes as probes to study the metabolism of liver microsomes from Chinese Bama miniature pigs. Nifedipine oxidation (NOD) and testosterone 6β-hydroxylation (6β-OHT) activities were similar between human liver microsomes and those from Bama miniature pigs. However, compared with those from humans, liver microsomes from Bama miniature pigs showed decreased phenacetin O-deethylation, coumarin 7-hydroxylation, and chlorzoxazone 6-hydroxylation activities, whereas dextromethorphan O-demethylation activity was increased. Ketoconazole selectively inhibited NOD and 6β-OHT activities in microsomes from Bama pigs, and 8-methoxypsoralen and tranylcypromine inhibited coumarin 7-hydroxylation in pig microsomes. However, furafylline and quinidine failed to selectively inhibit phenacetin O-deethylation and dextromethorphan O-demethylation in microsomes from Bama pigs, whereas chlormethiazole more efficiently inhibited coumarin 7-hydroxylation activity than chlorzoxazone 6-hydroxylation in pig microsomes. Our results suggest that liver microsomes from Chinese Bama miniature pigs are similar to those from humans in regard to metabolism of nifedipine and testosterone (both are probe substrates for human CYP3A4). In addition, chemical inhibitors used as specific probes for human P450 enzymes did not always show the same selectivity toward corresponding enzyme activities in liver microsomes from Bama pigs. However, ketoconazole (a potent inhibitor of human CYP3A4) could be used as a selective inhibitor probe for the NOD and 6β-OHT activities in liver microsomes from Chinese Bama miniature pigs.

关键词： 6β-OHT, testosterone 6β-hydroxylation CH, coumarin 7-hydroxylation CYP, cytochrome P450 CZH, chlorzoxazone 6-hydroxylation DMOD, dextromethorphan O-demethylation HPLC, high-performance liquid chromotography NOD, nifedipine oxidation POD, phenacetin O-deethylation UV, ultraviolet

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Magnetic and dielectric properties of low temperature fired ferrite/ceramic composite materials

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Progress in Natural Science:Materials International 2011年第1期21卷 21-26页

作者： wei-wei ling~(1,2),Huai-wu ZHANG~1,Ying HE~1,Yuan-xun LI~1,Yun-yan WANG~1 1.State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China,Chengdu 610054,China 2.Department of Communication Engineering,Chengdu University of Information Technology, Chengdu 610225,China [a] State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Chengdu 610054 China [b] Department of Communication Engineering Chengdu University of Information Technology Chengdu 610225 China

Ni-Cu-Zn ferrite/CaTiO3and Ni-Cu-Zn ferrite/BaTiO3composites which can be applied in low temperature co-fired ceramic（LTCC） technology were synthesized by conventional solid-state reaction at temperature lower than 950℃.Influence of the microstructures and the gap parameterδ/D on the complex permeability of the above two composites was *** modifiedδ/D values of the above two composites show a good fit to the magnetic circuit *** dielectric properties of the composites were predicted by the Maxwell-Garnctt effective medium theory and the discrepancy between measured and calculated values was analyzed.

关键词： ferrite/ceramic composite low temperature co-fired ceramic(LTCC) solid-state reaction magnetic properties dielectric properties

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Controlled Synthesis of Water-Soluble Lanthanide-Doped Nanomaterials

Controlled Synthesis of Water-Soluble Lanthanide-Doped Nanom...

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2011中国材料研讨会

作者： wei wei,Xue Teng,ling Huang School of Chemical and Biomedical Engineering,Nanyang Technological University 70 Nanyang Drive,Singapore 637457

＜正＞Due to the unique upconversion emission capability,long fluorescence lifetime,resistance to photobleaching,and relatively low or non cytotoxicity,lanthanide-doped nanomaterials

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Mob2p interacts with the protein kinase Cbk1p to function in cell polarity growth and cytokinesis in Aspergillus nidulans

Mob2p interacts with the protein kinase Cbk1p to function in...

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2006中国微生物学会第九次全国会员代表大会暨学术年会

作者： Jie Shi, wei-wei Chen, ling Lu Jiangsu Key Lab for Bioresource Technology, College of Life Science, Nanjing Normal University, Nanjing 210097, China

The molecular mechanisms that temporally and spatially coordinate cell morphogenesis with the cell cycle remain poorly understood. In the yeast ***, mob2p-orb6p is a widely expressed serine-threonine kinase complex, homolog of human Mob2-NDR that, has been implicated in cell proliferation and tumor progression. Due to the significance of Aspergillus fungi as human pathogens, it will

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一种新型检测饮用水中氰化物的方法

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安全与环境学报 2016年第6期16卷 321-325页

作者：白姣姣张健伟孙卫玲北京大学深圳研究生院环境与能源学院深圳市重金属污染控制与资源化重点实验室广东深圳518055 北京大学环境科学与工程学院水沙科学教育部重点实验室北京100871

氰化物为剧毒物质,针对氰化物研究出一种快速、可视化检测方法是非常有必要的。研究发现,荧光分子Singapore Tongue(SGT-5)与Hg^(2+)的混合体系(命名为Cyanogen Red,CNR)可以作为新的荧光传感器,对饮用水规定安全阈值内的CN^-实现快速... 详细信息

氰化物为剧毒物质,针对氰化物研究出一种快速、可视化检测方法是非常有必要的。研究发现,荧光分子Singapore Tongue(SGT-5)与Hg^(2+)的混合体系(命名为Cyanogen Red,CNR)可以作为新的荧光传感器,对饮用水规定安全阈值内的CN^-实现快速、可视化的检测。当水体中CN^-浓度为0.2~10μmol/L时,CNR的荧光值与CN^-浓度呈现良好线性关系(R^2=0.998),并且肉眼可见其荧光红色随CN^-浓度增大呈渐暗趋势。CNR对水体中常见的阴离子如Cl^-,SO_4^(2-),CO_3^(2-),HCO_3^-,NO_3^-和PO_4^-单一体系和混合体系都具有选择性。通过对14种实际饮用水样中滴加10μmol/L CN^-的准确测定,得出该方法相比较传统硝酸银滴定法具有许多优势,不但需样量少(100μL)、耗时短(1 min),而且检测限完全能够满足安全引用水中CN^-的最大允许浓度1.9μmol/L。

关键词：环境科学技术基础学科氰化物饮用水荧光传感器快速检测

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福建省市售水产品中寄生虫感染调查

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中国人兽共患病学报 2017年第6期33卷 564-568页

作者：林陈鑫林诗涵陈伟伟黄姝玲江典伟福建省疾病预防控制中心福州350001 福建省产品质量检验研究院福州350002

目的调查福建省市售水产品鱼、虾中寄生虫感染状况,为保障食品安全提供依据。方法采用分层随机抽样调查方法,以自然地域将福建省划分为闽东、闽南、闽西、闽北和闽中5个地区,收集各个地区农贸市场和超市的淡水或海水水产品为材料,采用... 详细信息

目的调查福建省市售水产品鱼、虾中寄生虫感染状况,为保障食品安全提供依据。方法采用分层随机抽样调查方法,以自然地域将福建省划分为闽东、闽南、闽西、闽北和闽中5个地区,收集各个地区农贸市场和超市的淡水或海水水产品为材料,采用消化法和压片法检测寄生虫囊蚴或幼虫。结果 2012-2016年检测淡水类水产品20种,寄生虫感染率为5.15%(130/2 524),其中囊蚴的感染率为3.72%(94/2 524),幼虫的感染率为1.43%(36/2 524);检查海水类水产品28种,寄生虫感染率为17.25%(88/510),均为异尖线虫。5个地区的寄生虫感染率分别为:闽东地区为10.38%(27/260)、闽南地区为5.84%(27/462)、闽西地区为4.63%(30/648)、闽北地区为4.64%(29/625)和闽中地区为9.91%(103/1 039)。结论福建省淡水类水产品受到寄生虫污染,不同地区流行情况有较大差异,海水类水产品的感染率相差很大。应加强食品安全卫生宣传,采取有效的防控策略,以保障食品安全。

关键词：水产品寄生虫感染调查福建省

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