检索结果-南通市图书馆

Protective effects of upregulated HO-1 gene against the apoptosis of human retinal pigment epithelial cells in vitro

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2021年第5期14卷 649-655页

作者： Yu Hong Yu-Ping Liang wei-qi chen Liu-Xia You qing-Feng Ni Xiu-Yun Gao Xiao-Rong Lin Department of Ophthalmology the Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Clinical Laboratory the Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

AIM:To investigate the protective effect of heme oxygenase-1(HO-1)against H_(2)O_(2)-induced apoptosis in human ARPE-19 ***:The lentiviral vector expressing HO-1 was prepared and transfected into apoptotic ARPE-19 cells induced by H_(2)O_(2).Functional experiments including cell counting kit-8(CCK-8)assay,flow cytometry(FCM)and mitochondrial membrane potential assay were ***:The ultrastructure of ARPE-19 cells was observed using transmission electron microscope(TEM).It was found that exogenous HO-1 significantly ameliorated H_(2)O_(2)-induced loss of cell viability,apoptosis and intracellular levels of reactive oxygen species(ROS)in ARPE-19 *** overexpression of HO-1 facilitated the transfer of nuclear factor erythroid-2-related factor 2(Nrf2)from cytoplasm to nucleus,which in turn upregualted expressions HO-1 and B-cell lymphoma-2(Bcl-2).Furthermore,HO-1 upregulation further inhibited H_(2)O_(2)-induced release of cysteinyl aspartate specific proteinase-3(caspase-3).CONCLUSION:Exogenous HO-1 protect ARPE-19 cells against H_(2)O_(2)-induced oxidative stress by regulating the expressions of Nrf2,HO-1,Bcl-2,and caspase-3.

关键词： retinitis pigmentosa heme oxygenase-1 ARPE-19 cell mechanism

Pediatric episcleral osseous choristomas:a case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2020年第10期13卷 1671-1674页

作者： Zi-Jing Huang Jian-Long Zheng De-Zhi Zheng Ding-Guo Huang Dong-Ping Tian wei-qi chen Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong Shantou 515041Guangdong ProvinceChina Department of Pathology Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

Dear Editor,We are writing to present a rare episcleral osseous choristomas in a 12-year-old *** are congenital benign mass composed of normal tissue located in an abnormal site[1].Ocular choristomas can be categorize... 详细信息

关键词： congenital epi ler

The synthesis and phase transition of 4'-methylphenyl 4"-[(4-alkoxy-2,3,5,6-tetrafluorophenyl)ethynyl]benzoates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 1994年第2期12卷 169-173页

作者： XU, Yu-Lian WANG, wei-Li chen, qi WEN, Jian-Xun Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

A homologous series of 4'-methylphenyl 4'-[(4-alkoxy-2,3,5,6-tetrafluorophenyl)ethynyl]-benzoates have been synthesized. Polarizing microscopic textural observation shows that such compounds exhibit enantiotropic nema... 详细信息

关键词： Liquid crystal 1,4-tetrafluorophenylene synthesis nematic phase.

Microbial ingress and in vitro degradation enhanced by glucose on bioabsorbable Mg-Li-Ca alloy

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2020年第4期5卷 902-916页

作者： Ling-Yu Li Zhuang-Zhuang Han Rong-Chang Zeng wei-chen qi Xiao-Fan Zhai Yi Yang Yun-Tian Lou Tingyue Gu Dake Xu Ji-Zhou Duan Corrosion Laboratory for Light Metals College of Material Science and EngineeringShandong University of Science and TechnologyQingdao266590China Institute of Oceanology Chinese Academy of SciencesQingdao266590China Shenyang National Laboratory for Materials Science Northeastern UniversityShenyang110819China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou450002China Department of Chemical&Biomolecular Engineering Russ College of Engineering and TechnologyOhio UniversityAthensOH45701-2979USA

Biodegradable magnesium alloys are challenging to be implanted in patients with hyperglycemia and diabetes.A hypothesis is suggested that glucose accelerates microbial ingress and in vitro degradation of Mg-Li-Ca *** resistance and mechanical properties was demonstrated using electrochemical,hydrogen evolution and tensile *** bacteria from Hank's solution were isolated via 16S rRNA gene *** results revealed that Mg-1Li-1Ca alloy exhibited different responses to Hank's solution with and without *** solution acidity was ascribed to Microbacterium hominis and Enterobacter xiangfangensis,indicating that glucose promoted microbial activity and degradation and deterioration in mechanical property of Mg-1Li-1Ca alloy.

关键词： Glucose Magnesium Bacteria Biomaterial Biodegradation

Biomechanical Comparison of Two Kinds of Internal Fixation in a Type C Zone II Pelvic Fracture Model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第17期128卷 2312-2317页

作者： Tao Wu wei chen qi Zhang Zhan-Le Zheng Hong-Zhi Lyu Yun-wei Cui Xiao-Dong cheng Ying-Ze Zhang Yan-Jiang Yang Department of Orthopaedics Third Hospital Hebei Medical University Shijiazhuang Hebei 050051 China

Background： Unstable pelvic fractures are complex and serious injuries. Selection of a fixation method for these fractures remains a challenging problem for orthopedic surgeons. This study aimed to compare the stability of Tile C pelvic fractures fixed with two iliosacral （IS） screws and minimally invasive adjustable plate （MIAP） combined with one IS screw. Methods： This study was a biomechanical experiment. Six embalmed specimens of the adult pelvis were used. The soft tissue was removed from the specimens, and the spines from the fourth lumbar vertebra to the proximal one-third of both femurs were retained. The pubic symphysis, bilateral sacroiliac joints and ligaments, bilateral hip joints, bilateral sacrotuberous ligaments, and bilateral sacrospinous ligaments were intact. Tile C pelvic fractures were made on the specimens. The symphysis pubis was fixed with a plate, and the fracture on the posterior pelvic ring was fixed with two kinds of internal fixation in turn. The specimens were placed in a biomechanical machine at a standing neutral posture. A cyclic vertical load of up to 500 N was applied, and displacement was recorded. Shifts in the fracture gap were measured by a grating displacement sensor. Statistical analysis used： Paired-samples t-test. Results： Under the vertical load of 100, 200, 300, 400, and 500 N, the average displacement of the specimens fixed with MIAP combined with one IS screw was 0.46, 0.735, 1.377, 1.823, and 2.215 mm, respectively, which was significantly lower than that of specimens fixed with two IS screws under corresponding load （P 〈 0.05）. Under the vertical load of 500 N, the shift in the fracture gap of specimens fixed with MIAP combined with one IS screw was 0.261 ± 0.095 mm, and that of specimens fixed with two IS screws was 0.809 ± 0.170 mm. The difference was significant （P 〈 0.05）. Conclusion： The stability of Tile C pelvic fractures fixed with MIAP combined with one IS screw was better than that fixed with two IS screws.

关键词： Biomechanics Internal Fixation Pelvis Unstable

Ammonia pyrolysis oxidation excited by nanosecond pulsed discharge:Global/fluid models hybrid solution

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 385-396页

作者： Mingming Zhang Hanyu Wu qi chen Jiaxin Yang Bonan Liu School of Mechanical Electronic and Control Engineering Beijing Jiaotong University China University of Petroleum

The kinetic characteristics of plasma-assisted oxidative pyrolysis of ammonia are studied by using the global/fluid models hybrid solution ***,the stable products of plasma-assisted oxidative pyrolysis of ammonia are *** results show that the consumption of NH3/O2and the production of N2/H2change linearly with the increase of voltage,which indicates the decoupling of nonequilibrium molecular excitation and oxidative pyrolysis of ammonia at low ***,the detailed reaction kinetics mechanism of ammonia oxidative pyrolysis stimulated by a nanosecond pulse voltage at low pressure and room temperature is *** on the reaction path analysis,the simplified mechanism is *** detailed and simplified mechanism simulation results are compared with experimental data to verify the accuracy of the simplified ***,based on the simplified mechanism,the fluid model of ammonia oxidative pyrolysis stimulated by the nanosecond pulse plasma is established to study the pre-sheath/sheath behavior and the resultant consumption and formation of key *** results show that the generation,development,and propagation of the pre-sheath have a great influence on the formation and consumption of *** consumption of NH3by the cathode pre-sheath is greater than that by the anode pre-sheath,but the opposite is true for OH and O（1S）.However,within the sheath,almost all reactions do not ***,by changing the parameters of nanosecond pulse power supply voltage,it is found that the electron number density,electron current density,and applied peak voltages are not the direct reasons for the structural changes of the sheath and ***,the discharge interval has little effect on the sheath structure and gas mixture *** research results of this paper not only help to understand the kinetic promotion of non-equilibrium excitation in the process of oxidative pyrolysis but also help to explore th

关键词： Nanosecond pulsed discharge Ammonia Oxidative pyrolysis Fluid model Global model

Concept and Evaluation of Ecosystem Intrinsic Value

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Agricultural Science and Technology(B) 2015年第6期5卷 401-409页

作者： Luo Ping Zhang Hong Ni Xu Hua Xia Sheng wei qi chen qin Hua Fang The College of the Environment and Ecology Xiamen University Xiamen Fujian 361102 China

Ecosystem valuation can serve as a basis of scientific support for decision-making. So far, the most popular methods for ecosystem valuation are ecosystem service valuation （ESV）, which is based on the utility of ecosystem to human beings rather than on the objective value of the ecosystem. After more than 10 years＇ application, it has been found that all losses of ESV were about 10% of the benefits of human activities. In this paper, the ecosystem intrinsic value （EIV） is defined. EIV is an objective value that emerges from the existence, structures, functions and processes of ecosystem, but independent with man, man＇s will and preferences. The valuating approach and methods used for EIV were developed by using energy approach and the methods of emergy analysis and eco-exergy analysis. The EIV calculated by emergy from the substance, energy and information of ecosystem and by eco-exergy from the structure and function of ecosystem represents the existent value and the externally working capacity of ecosystem, respectively. The approach and methods of EIV evaluation were applied to Xiamen Bay, China. The results showed that the marine EIV in Xiamen Bay was 209 billion RMB, including 116 billion RMB of emergy and 92.4 billion RMB of eco-exergy in 2010, nearly 30 times of ESV and 8.5 times of the GDP of Xiamen marine industry in 2010. The EIV in unit area of Xiarnen Bay is more than 10 times higher than the average global ESV in estuaries. It implied a potential undervaluation to ecosystem value by ESV calculation, which may mislead decisions-making processes.

关键词： Ecosystem intrinsic value concept evaluation approach methods.

STUDIES ON THE CHEMICAL CONSTITUENTS OF TAXUS CUSPIDATA

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1993年第10期4卷 887-890页

作者： Xiao Jie Tong wei Shuo Fang Jin Yun Zhou Cun Heng He wei Ming chen qi cheng Fang Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050

From the methylene chloride extract of the leaves and stems of Taxus cuspidata Sieb et Zucc twelve taxane diterpenoids have been *** structures of two novel taxane diterpenes,named 10-deacetyltaxinine B(1)and taxacust... 详细信息

关键词： HNMR

Taxayuntin I from Thous Yunnanensis

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1999年第1期10卷 43-44页

作者： Jin Yun ZHOU Pei Ling ZHANG wei Ming chen and qi cheng FANG(Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking UnionMedical College, Beijing 100050)

Taxayuntin I, a new 11I (15→1)abeotaxane. was isolated from the leaves and stems ofTaxes yunnanensis. Its structure was elucidated on the basis of spectroscopic data.

关键词： TaxusyUnnanensis taxoids abeotaxane taxayuntin I