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分布式协同动态任务规划的建模与一体化求解方法

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中国惯性技术学报 2017年第4期25卷 523-529页

作者：崔乃刚吴蔚楠郭继峰哈尔滨工业大学航天学院哈尔滨150001

以多异构无人机执行侦查、打击、评估任务为背景,开展了协同任务规划问题建模、一体化求解算法设计。采用分布式规划框架及图论思想对问题进行建模,且将无人机避碰、燃油、任务执行次序作为约束条件,并充分考虑任务分配与路径规划存在... 详细信息

以多异构无人机执行侦查、打击、评估任务为背景,开展了协同任务规划问题建模、一体化求解算法设计。采用分布式规划框架及图论思想对问题进行建模,且将无人机避碰、燃油、任务执行次序作为约束条件,并充分考虑任务分配与路径规划存在的强耦合特性,采用禁忌/遗传算法,设计包含任务序列和路径位姿点的基因编码,将问题进行一体化求解。结果表明:算法能够适用于动态任务场景,且能够较为快速地解决任务空间较为复杂的规划问题。

关键词：异构无人机一体化求解协同任务规划分布式决策 Dubins路径禁忌/遗传混合算法

高温合金高速精铣表面完整性建模及切削参数优化研究

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中国机械工程 2017年第16期28卷 1906-1913页

作者：孙涛梁晋李登万魏斌郭楠西安交通大学机械制造系统工程国家重点实验实西安710049 四川工程职业技术学院四川省高温合金切削工艺技术工程实验室德阳618000

基于均匀设计法设计了含定性因素混合水平的高速精铣试验方案,用最优回归子集法建立了切削力、切削温度、表面完整性的多元二次回归模型,回归效果显著;重点分析了切削条件对表面完整性的影响规律;基于回归模型建立了高温合金高速精铣切... 详细信息

基于均匀设计法设计了含定性因素混合水平的高速精铣试验方案,用最优回归子集法建立了切削力、切削温度、表面完整性的多元二次回归模型,回归效果显著;重点分析了切削条件对表面完整性的影响规律;基于回归模型建立了高温合金高速精铣切削参数多目标优化模型,验证结果显示模型具有较高的预测精度。研究结果对高温长寿命工作下的试件表面质量控制和切削参数优化具有指导性意义。

关键词：高温合金高速精铣表面完整性参数优化均匀设计

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 103-113页

作者： CHEN Wuxing CHEN Shuang YU Yan ZHANG Jiangyi XU Haiyang guo wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian guo Kunpeng Li wei Yue Nam‑Young Kim Yang Li guozhen Shen Jong‑Chul Lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

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浅谈煤矿矿井提升系统

能源与节能 2012年第10期 14-15页

作者：南卫国山西约翰芬雷华能设计工程有限公司山西太原030000

简要介绍了煤矿矿井提升系统的组成和分类,详细阐述了矿井提升机的设计要点。

关键词：矿井提升系统提升机

High-performance poly(aromatic pyridine) copolymers with crown ether moieties for high temperature polymer electrolyte membrane fuel cells

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Science China Chemistry 2025年

作者： Qian Wang Songhao Zhao Yunpeng guo wei wei Lele Wang Jingshuai Yang Department of Chemistry College of Sciences Northeastern University Institute of Metal Research Chinese Academy of Sciences

This study concentrates on the development of high temperature polymer electrolyte membranes（HT-PEMs）, which are essential components for HT-PEM fuel cells（HT-PEMFCs）. Although the phosphoric acid（PA）-doped polybenzimidazole（PBI） has been regarded as the successful HT-PEM, this system still suffers from several challenges, including the use of carcinogenic monomers, complex synthesis procedures, and poor solubility in organic solvents. To develop more cost-effective, readily synthesized and high-performance alternatives, this study employs a simply superacid-catalyzed Friedel-Crafts reaction to synthesize a series of poly（triphenyl-co-dibenzo-18-crown-6 pyridine） copolymers, denoted as P(TPx%-co-CEy%), using ptriphenyl, dibenzo-18-crown-6 and 4-acetylpyridine as monomers. The copolymerized hydrophilic and bulky crown ether unites introduce large free volumes and multiple interaction sites with PA molecules, as elucidated by theoretical *** microphase separation structures are formed as confirmed by atomic force microscope（AFM）, transmission electron microscopy（TEM） and small-angle X-ray scattering（SAXS）. Thus P(TPx%-co-CEy%) membranes exhibit excellent PA absorption and proton conduction abilities. For example, after immersing in 85 wt% PA at 30 °C, the P(TP91%-co-CE9%) membrane achieves a PA doping content of 205% and a high conductivity of 0.138 S cm-1at 180 °C, while maintaining a tensile strength of 7.5 MPa at room temperature. Without humidification and backpressure, the peak power density of an H2-O2cell equipped with P(TP91%-co-CE9%)/205%PA reaches nearly 1200 mW cm-2, representing one of the highest performances reported for PA-doped HT-PEMs to date. This work demonstrates the enormous potential of poly（triphenyl-co-crown ether pyridine） membranes in the HT-PEMFC applications.

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Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging

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Science China Chemistry 2025年第01期 26-34页

作者： Yutao Zhang Juan Li wei-Hong Zhu Zhiqian guo Shanghai Key Laboratory of Functional Materials Chemistry Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology State Key Laboratory of Bioreactor Engineering Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell MetabolismEast China University of Science & Technology

Sequence-activated chemiluminescence(CL) technique offers a unique approach to detecting specific biomolecules or cellular events with high sensitivity and spatial resolution. The fundamental principle behind sequence-activated CL probes involves tailoring highly-controllable CL signals in response to specific sequences or events of interest, thus enabling high-contrast signals under complex physiological conditions. This sequential activation could be triggered by enzymes, reactive oxygen species(ROS), biothiols or changes in the microenvironment. These unique sequence-activated CL probes bestow several advantages, including minimal background, deep-tissue penetration, and the ability of non-invasive or minimally invasive detection. The sequence-activated CL techniques represent a significant advancement in molecular imaging and diagnostics. In this mini-review, we focus on the latest developments in sequential CL probes, addressing the technical challenges and discussing the future trajectory by harnessing CL signaling and molecular recognition.

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Capsaicin Regulates Mitochondrial Fission to Promote Melanoma Cell Apoptosis

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International Journal of Dermatology and Venereology 2021年第3期4卷 140-151页

作者： Jing-Jing Ma Yu-Qi Yang Sen guo Hui-Na Wang Xiu-Li Yi Tao Zhao Lin Liu Qiao Yue Yu Liu Qiong Shi Tian-Wen Gao wei-nan guo Chun-Ying Li Department of Dermatology Xijing HospitalThe Fourth Military Medical UniversityXi’anShaanxi 710032China

Objective:Capsaicin(CPS)is a major component of the red pepper,and its anti-tumor property has been ***,the underlying mechanism of this anti-tumor effect has not been fully clarified,so we conducted this study to evaluate the role of mitochondrial fission and subsequent mitochondrial dysfunction in CPS-induced apoptosis of melanoma ***:Two melanoma cell lines and melanocytes were treated with CPS alone or in combination with ruthenium red(a transient receptor potential vanilloid 1[TRPV]antagonist),Z-VAD-FMK(a pan-caspase inhibitor),or N-acetyl-Lcysteine(an antioxidant).Cell vitality was tested using a cell counting kit-8 *** expression levels of related proteins were examined by Western ***,intracellular reactive oxygen species,mitochondrial membrane potential,adenosine triphosphate levels,and mitochondrial dynamics were analyzed by flow cytometry,luminometry,and confocal laser microscopy,respectively,and compared between ***:CPS treatment significantly inhibited the vitality of melanoma cells(For A2058 cells:0 vs.120 mmol/L:[100.00%±0%]vs.[51.02%±6.40%],P<0.05;For WM35 cells:0 vs.120 mmol/L:[100.00%±0%]vs.[51.80%±3.45%],P<0.05)but exerted less impact on normal *** promoted melanoma cell apoptosis through TRPV channels and the caspase *** treatment then led to TRPV channel-dependent mitochondrial dysfunction with an increase in reactive oxygen species generation(For A2058 cells:CPS ***+RR:[2.34±0.30]vs.[1.34±0.12],P<0.05;For WM35 cells:CPS ***+RR:[2.25±0.25]vs.[1.65±0.13],P<0.05),dissipation of the mitochondrial membrane potential(Control ***:[1.00±0]vs.[0.61±0.08],P<0.05),and adenosine triphosphate reduction(P<0.05).In addition,reactive oxygen species generation contributed to CPS-induced melanoma cell *** fission was subsequently proved to connect CPS treatment to mitochondrial dysfunction,which was also TRPV channel-dependent,thereby inducing melanoma cell a

关键词： capsaicin melanoma mitochondrial dysfunction mitochondrial fission TRPV channels

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment

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Neural Regeneration Research 2025年第9期20卷 2598-2610页

作者： Yi Wang Yuning Li Yakun Gu wei Ma Yuying Guan Mengyuan guo Qianqian Shao Xunming Ji Jia Liu Department of Clinical Laboratory Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersBeijing Advanced Innovation Center for Big Data-based Precision MedicineCapital Medical UniversityBeijingChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this *** aims of this study were to(1)determine the specific relationship between hypoxic andα-synuclein during the occur of poststroke cognitive impairment and(2)assess whether the serum phosphorylatedα-synuclein level can be used as a biomarker for poststro ke cognitive *** found that the phosphorylatedα-synuclein level was significantly increased and showed pathological aggregation around the cerebral infa rct area in a mouse model of ischemic *** addition,neuronalα-synuclein phosphorylation and aggregation were observed in the brain tissue of mice subjected to chronic hypoxia,suggesting that hypoxia is the underlying cause ofα-synuclein-mediated pathology in the brains of mice with ischemic *** phosphorylatedα-synuclein levels in patients with ischemic stroke were significantly lower than those in healt hy subjects,and were positively correlated with cognition levels in patients with ischemic ***,a decrease in serum high-density lipoprotein levels in stroke patie nts was significantly correlated with a decrease in phosphorylatedα-synuclein *** ischemic stroke mice did not show significant cognitive impairment or disrupted lipid metabolism 14 days after injury,some of them exhibited decreased cognitive function and reduced phosphorylatedα-synuclein *** together,our results suggest that serum phosphorylatedα-synuclein is a potential biomarker for poststroke cognitive impairment.

关键词： biomarker high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment