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Chinese Chemical Letters 2011年第6期22卷 749-752页

作者： wei huang ming Lv Zhong Gao Gao Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050 China

Copolymers mPEG-PCL were prepared and grafted onto polyethylenimine（PEI） to synthesize copolymers mPEG-PCL-g-PEI with low *** mPEG-PCL-g-PEI could condense siRNA to form nanoparticles with positive zeta *** nanoparticles could delivery siRNA into cells to effectively inhibit the expression of target gene,which suggested that mPEG-PCL-g -PEI could serve as a highly efficient vector for siRNA delivery.

关键词： Copolymers Nanoparticles Vector Synthesis

Thermal and Mechanical Properties of Graphene-Titanium Composites Synthesized by Microwave Sintering

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Acta Metallurgica Sinica(English Letters) 2016年第8期29卷 707-713页

作者： Wen-Zhi Yang wei-ming huang Zhi-Feng Wang Fu-Jun Shang wei huang Bao-Yu Zhang Ningbo Branch of China Academy of Ordnance Science College of Mechanical Engineering and Mechanics Ningbo University

The x wt%graphene-Ti composites（x = 0,0.2,0.3 and 0.4） were obtained using the powder metallurgy *** X-ray diffraction results demonstrated that the peak intensity of graphene increased monotonically with increasing graphene ***,the number of grain boundary and interface between graphene and matrix increased as graphene increased,which led to a sharp rise of thermal *** thermal conductivity and specific heat capacity of composites initially decreased drastically with addition of graphene,but then increased with increasing graphene content from 0.2 to 0.4 wt%.This phenomenon was connected with the graphene content and the characteristics of Ti matrix（pores,grain boundary and interface between graphene and matrix）.The variation of the compressive strength of composites was attributed to the interaction effects of the average grain size of the Ti matrix（d_m） and the volume fraction（V_f） and aspect ratio（A） of graphene.

关键词： Graphene Metal-matrix composites Thermal properties Compressive strength

Coronary microembolization induced myocardial contractile dysfunction and tumor necrosis factor-α mRNA expression partly inhibited by SB203580 through a p38 mitogen-activated protein kinase pathway

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Chinese Medical Journal 2011年第1期124卷 100-105页

作者： LI Lang QU Nan LI Dong-hua WEN wei-ming huang wei-qiang Department of Cardiology First Affiliated Hospital of Guangxi Medical University Nanning Guangxi 530021 China

Background The microemboli produced during spontaneous plaque rupture and ulceration and during coronary intervention will reduce coronary reserve and cause cardiac dysfunction. It is though that inflammation caused by the microinfarction induced by the microembolization may play an essential role. It is known that the activation of p38 mitogen-activated protein kinases （MAPK） in both infected and non-infected inflammation in myocardium may cause a contractile dysfunction. But the relation between the activation of p38 MAPK and microembolization is still unknown. Methods Sprague-Dawley rats were randomly divided into three groups： Sham group, coronary microembolization （CME） group and SB203580 group （n=-10 per group）. CME rats were produced by injection of 42 pm microspheres into the left ventricle with occlusion of the ascending aorta. SB203580, a p38 MAPK inhibitor, was injected into the femoral vein after the injection of microspheres to make the SB203580 group. Left ventricular ejection fraction （LVEF） was determined by echocardiography. The protein concentration of P38 MAPK in the myocardium was assessed by Western blotting. The relative expression of mRNA for tumor necrosis factor （TNF）-a was assessed by the technique of semi-quantitative polymerase chain reaction amplification. Results LVEF was depressed at three hours up to 12 hours in the CME group. Increased p38 MAPK activity and TNF-a mRNA expression were observed in the CME group. The administration of SB203580 partly inhibited p38 MAPK activity, but did not fully depress the TNF-α expression, and partly preserved cardiac contractile function. Conclusions p38 MAPK is significantly activated by CME and the inhibition of p38 MAPK can partly depress the TNF-a expression and preserve cardiac contractile function.

关键词： p38 mitogen-activated protein kinases tumor necrosis factor-alpha microcirculation myocardial contraction

Thermal Aspects for Face Grinding of Ceramics

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厦门大学学报（自然科学版） 2002年第S1期41卷 123-124页

作者： SHEN Jian-yun, ZENG wei-ming, huang Hui, XU Xi-peng (College of Mechanical Engineering and Automation, Huaqiao University , Quanzhou 362011, China)

To meet the increasing demand on the quality and co st of precision structural components, extensive studies on high efficiency and pr ecision machining of ceramic materials, including face grinding, have been condu cted over the past several years. However, there are few reports about the mecha nism in face grinding of ceramics, especially the thermal aspects during the gri nding process. In the present study, experiments of face grinding two typical ce ramics were carried out to study themal aspects at the wheel-workpiece contact zone. The present investigation was undertaken to experimentally study the energy part ition to workpiece and thermal characteristics during face grinding of two typic al ceramics. For this purpose, grinding temperature distribution in the ceramics workpiece was calculated with the classic moving heat source theory. The grindi ng temperature at the wheel-workpiece contact zone was measured under different machining conditions using a grindable foil thermocouple. Combining the analyti cal results and the experimental result for temperatures, the mechanism of energ y partition in face grinding of ceramic materials was discussed. According to the experimental results and the comparison of theoretic and measur ed temperature profiles, temperature characteristics and mechanism of energy par tition in face grinding of ceramic materials were discussed. Temperature rise in the workpiece and energy partition during the grinding process were found to be derictly related to the machining parameters and the mechanism of mateirial rem oval. The increasing of either v w or a p can lead to an increase of temperatu re. The temperature rise in Si 3N 4 is much lower than that in ZrO 2 under th e same condition, which might be attributed to the different material removal me chanisms. Both temperatures in dry grinding and in wet grinding are not high eno ugh to cause thermal damage to ceramic materials. The value of energy partition increases with the increa

关键词： ceramic face grinding grinding temperature

Using free style proximal radial forearm free flaps for head and neck reconstructions

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中国口腔颌面外科杂志 2008年第B5期6卷 187-188页

作者： Jeng-Yee Lin wei-Chao huang ming-Huei Cheng David CC Chuang Fu-Chan wei Department of Plastic and Reconstructive Surgery Chang GungMemorial Hospital Taoyuan Taiwan China Xiamen ChangGung Memorial Hospital China

Over exposed image information recovery via stochastic resonance

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Chinese Physics B 2012年第4期21卷 301-307页

作者：杨异秉陶伟明黄家闽徐博侯 Department of Mechanics State Key Laboratory of Fluid Power Transmission and ControlZhejiang UniversityHangzhou 310027China

Over exposure is rather annoying in photo taking. However, in some severe light conditions over exposure is inevitable using conventional cameras due to the limitation of dynamic range of the image sensor. The over exposed information would be completely lost and unrecoverable. In order to cope with this problem, we propose a novel technique in which the noise is used to enlarge the dynamic range of the image sensor. The essential mechanism that noise contributes to the information recovery is investigated. It is also proved that the visibility of regained information can reach the peak when specifically added noise is synchronized with the image sensor, thus activating the phenomenon of stochastic resonance （SR）. Four different types of noises are investigated to show the effects of variant distributions on the quality of recovered information. The experimental outcomes are consistent with our theoretical results, which indicates that the SR-based lost information recovery is quite promising.

关键词： stochastic resonance image information recovery dynamic range over exposure

Synthesis of LCuSCF3 Complexes and Their Reactivity towards Trifluoromethylthiolation of Aryl Halides

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Synthesis of LCuSCF3 Complexes and Their Reactivity towards ...

Enhancement of motor functional recovery in thoracic spinal cord injury: voluntary wheel running versus forced treadmill exercise

中国化学会第六届全国结构化学学术会议

作者： Zhi-Qiang Weng~*,wei-ming He,Cao-huang Chen Department of Chemistry,Fuzhou University,Fujian 350108,China

Aryl trifluoromethyl thioethers(ArSCF) exhibit significant biological activity and have important applications in the pharmaceutical,agricultural *** has been considerable effort in both academic and industrial laboratories directed at achieving straightforward,efficient,high yielding,and eco-friendly preparation of *** part of our efforts on development of copper-catalyzed synthesis of

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao Younghye Moon Chen Chen Nai-Kui Liu Xiao-ming Xu wei Wu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary exercise

Effect of Ti Additions on Mechanical and Thermodynamic Properties of W-Ti Alloys: A First-principles Study

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 246-257页

作者： ZHANG Jian NIE wei huang Jin ZHU Ke LIU Ruxia ZHANG Ruizhi LUO Guoqiang SHEN Qiang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China

The mechanical and thermodynamic properties of W-Ti alloys(including W_(15)Ti_(1),W_(14)Ti_(2),W_(12)Ti_(4) and W_(8)Ti_(8) alloys)were investigated by the first-principles approach based on density functional *** results indicate that W-Ti alloys except W_(8)Ti_(8) are thermodynamically *** modulus and hardness of W-Ti alloys are smaller than those of pure tungsten and gradually decrease with increasing Ti ***,their B/G ratios and Poisson's ratios exceed those of pure tungsten,suggesting that the introduction of Ti decreases the mechanical strength while enhancing the ductility of W-Ti *** thermal expansion coefficients for W-Ti alloys all surpass those of pure tungsten,indicating that the introduction of titanium exacerbates the thermal expansion behavior of W-Ti ***,elevated pressure has the capacity to suppress the thermal expansion tendencies in titanium-doped tungsten *** study offers theoretical insights for the design of nuclear materials by exploring the mechanical and thermodynamic properties of W-Ti alloys.

关键词： first-principles mechanical properties thermodynamic properties tungsten-titanium alloys

MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen Wang wei ming Longfu Chen Tianliang Song Moxi Yele Hao Zhang Long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng Wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance