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The effectiveness and safety of HuangQiXiXin decoction for cough variant asthma:protocol for a systematic review

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Clinical Research Communications 2022年第2期5卷 5-8页

作者： Qing-Qing Xia Cong Wang Yu-Feng Zhang wei-long jiang Jia Qi Department of Respiratory Medicine Jiangyin Hospital of Traditional Chinese MedicineJiangyinJiangsu 214400China Department of Pharmacy Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

Objective:A comprehensive and updated systematic review is needed to evaluate the effectiveness and safety of HuangQiXiXin decoction(HQXXD)for cough variant asthma(CVA).The aim of this systematic review protocol is to comprehensively assess the effectiveness and safety of HQXXD for ***:An overall search for studies in main English and Chinese electronic databases from their inception to January 2021 will be *** controlled trials regarding HQXXD for CVA will be *** will use RevMan 5.3 software to perform statistical analysis and ***:The findings of this systematic review will be disseminated through peer-reviewed ***:The systematic review will provide more evidence regarding the effectiveness and safety of HQXXD for CVA.

关键词： HuangQiXiXin decoction cough variant asthma protocol systematic review

Small-Scale Duplications Play a Significant Role in Rice Genome Evolution

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Rice science 2005年第3期12卷 173-178页

作者： Guo Xin-yi Xu Guo-hua ZHANG Yang Hu wei-min FAN long-jiang Institute of Crop Science/Institute of Bioinformatics Zhejiang University Hangzhou 310029 China

Genes are continually being created by the processes of genome duplication （ohnolog） and gene duplication （paralog）. Whole-genome duplications have been found to be widespread in plant species and play an important role in plant evolution. Clearly un-overlapping duplicated blocks of whole-genome duplications can be detected in the genome of sequenced rice （Oryza sativa）. Syntenic ohnolog pairs （ohnologues） of the whole-genome duplications in rice were identified based on their syntenic duplicate lines. The paralogs of ohnologues were further scanned using multi-round reciprocal BLAST best-hit searching （E〈e^-14）. The results indicated that an average of 0.55 sister paralogs could be found for every ohnologue in rice. These results suggest that small-scale duplications, as well as whole-genome duplications, play a significant role in the two duplicated rice genomes.

关键词： small-scale duplication ohnologue genome evolution Oryza sativa Arabidopsis

Construction of potential idiopathic pulmonary fibrosis related microRNA and messenger RNA regulatory network

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Chinese Medical Journal 2021年第5期134卷 584-586页

作者： Yu-Feng Zhang Li-Na Gu Jia Qi Qing-Qing Xia Li-Jun Tian wei-long jiang Meng-Shu Cao Department of Respiratory Medicine Jiangyin Hospital of Traditional Chinese MedicineJiangyin Hospital Affiliated to Nanjing University of Chinese MedicineJiangyinJiangsu 214400China Department of Pulmonary and Critical Care Medicine Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingJiangsu 210008China Department of Pulmonary and Critical Care Medicine Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjingJiangsu 210008China Department of Pharmacy Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Critical Care Medicine Nantong Third People's HospitalNantong UniversityNantongJiangsu 226001China

To the Editor:Idiopathic pulmonary fibrosis(IPF)is a kind of lung disease characterized by chronic and progressive pulmonary fibrosis with unknown etiology,whose pathological manifestation is usual interstitial pneumonia.111 However,the prognosis of IPF was still poor,and the median survival time after diagnosis was about 2 to 3 years Therefore,it seems important to seek and develop an effective therapeutic modality for *** base pairs of intramolecular complementary sequences of messenger RNA(mRNA),microRNA(miRNA)plays a key role in RNA silencing and post-transcriptional gene expression regulation.

关键词： diagnosis lung prognosis

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合成信息系统与予信息系统的属性特征

计算机工程 2007年第17期33卷 7-9页

作者：邵明文龙卫江清华大学自动化系华南理工大学计算机科学与工程学院广州510640

数据库的合成和分解在实际应用中是一个很重要的问题,它所对应的数学模型就是信息系统的合成与分解,该文给出了对象合成信息系统、属性合成信息系统、对象子信息系统及属性子信息系统的定义,讨论了合成信息系统、子信息系统与原信息系... 详细信息

数据库的合成和分解在实际应用中是一个很重要的问题,它所对应的数学模型就是信息系统的合成与分解,该文给出了对象合成信息系统、属性合成信息系统、对象子信息系统及属性子信息系统的定义,讨论了合成信息系统、子信息系统与原信息系统等属性特征之间的关系。

关键词：信息系统粗糙集属性约筒不必要属性必要属性

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

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Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-long Zhou wei-Jin jiang Ji Yu Mao-Jun Yao Yun-Tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

A network pharmacology approach to explore the mechanism of Kangguan decoction in the treatment of coronavirus disease 2019 with preliminary verification

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TMR Integrative Medicine 2021年第25期5卷 1-24页

作者： wei-long jiang Yu-Feng Zhang Meng-Ying Liu Su-Yan Zhang Jun-Xian Xu Min Li Hong Xue Li-Jun Tian Xu-Dong Han Department of Respiratory Medicine Jiangyin Hospital of Traditional Chinese MedicineJiangyin Hospital Affiliated to Nanjing University of Chinese MedicineJiangyin 214400China Department of Pulmonary and Critical Care Medicine Nanjing Drum Tower Hospital Clinical College of Nanjing Medical UniversityNanjing210008China Department of Critical Care Medicine Nantong Third People's HospitalNantong UniversityNantong 226001China Department of Traditional Chinese Medicine Nantong Third People's HospitalNantong UniversityNantongJiangsu 226001China Department of Infectious Disease Nantong Third People's HospitalNantong UniversityNantongJiangsu 226001China

Objective:To explore the mechanism of Kangguan decoction in the treatment of coronavirus disease 2019(COVID-19)and then perform preliminary ***:The effective compounds and target genes of Kangguan decoction were obtained from Traditional Chinese Medicine Systems Pharmacology Database and Analysis ***-19 related target genes were searched in the GeneCards *** active target genes of Kangguan decoction acting on COVID-19 were identified to perform GO function enrichment and KEGG pathway enrichment *** compound-target network and protein-protein interaction were constructed;Molecular docking simulations of macromolecular protein target receptors and their corresponding compounds were *** clinical data of COVID-19 patients were retrieved from their electronic medical records of Nantong Third People's ***:We screened out 137 effective compounds and 274 effective target genes of Kangguan decoction from *** active target genes of Kangguan decoction were compared with the COVID-19 related target genes,and 63 active target genes for Kangguan decoction acting on COVID-19 were *** function enrichment and KEGG pathway enrichment analysis were *** compound-target network and PPI network were constructed and the key compounds and key targets were selected to construct a key compound-target ***,the binding of the target and its corresponding components was verified by molecular docking and two clinical cases with obvious clinical efficacy after Kangguan decoction application were ***:The pharmacological mechanism of Kangguan decoction acting on COVID-19 has been explored,and the active compounds and targets of Kangguan decoction acting on COVID-19 and clinical efficacy for Kangguan decoction treating COVID-19 patients have been preliminarily verified.

关键词： Kangguan decoction Coronavirus disease 2019 Network pharmacology Molecular docking Clinical efficacy Quercetin PTGS2 Interleukin-6

Primary Studies on Burnup Estimation of Irradiated Uranium by Dtermining 236U/238U in Contaminated Environmental Samples jiang Xiao-yan,ZHANG Ji-long,ZOU wei,Chang Zhi-yuan

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Primary Studies on Burnup Estimation of Irradiated Uranium b...

Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

作者： jiang Xiao-yan ZHANG Ji-long ZOU wei Chang Zhi-yuan

U/U of the environmental sample can indicate the existence of uranium irradiation,and even can be uesd to estimate the burnup of nuclear spent fuel.A study on the burnup estimation of irradiated uranium which was mixed with natural uranium was carried out by measuring the U/U and U/U in the samples by using MC-ICP-MS. According to the equation(1) and(2),a programme for calculating the burnup of the irradiated

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen Shen Xiaoming Xiao Zhichao Li Qi Zhou wei Yang Bin jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

4MW EAST-NBI离子源引出系统装配

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核聚变与等离子体物理 2012年第4期32卷 351-355页

作者：李军胡纯栋谢亚红韦江龙中国科学院等离子体物理研究所合肥230031

根据EAST-NBI大面积束引出系统的特点及装配要求,研究合理的装配方法。通过多种装配方法来消除装配中产生的误差,以到达最大误差小于0.05mm,真空接口漏率小于1×10 7Pa.L.s 1,冷却水管耐压1MPa,通过100kV的静电耐压测试,并进行了离子束... 详细信息

根据EAST-NBI大面积束引出系统的特点及装配要求,研究合理的装配方法。通过多种装配方法来消除装配中产生的误差,以到达最大误差小于0.05mm,真空接口漏率小于1×10 7Pa.L.s 1,冷却水管耐压1MPa,通过100kV的静电耐压测试,并进行了离子束引出,初步验证了引出系统装配的成功,支持兆瓦级强流离子源的研制。

关键词：强流离子源束引出系统装配