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One-year status of hepatic venous pressure gradient measurement from 85 hospitals in China

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Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao wang Ting Cui linpeng Zhang Zhiping yan Lei li Jinjun Chen junhui Sun Hua Xiang He Zhu Hao wu jiancuo Gengzang Feng Zhang wei wu Guohong Cao wuhua Guo haibin Shi Hui Xue Guangjun Huang qiang yu Meng Niu Huiling Xiang Derun Kong wei Gou Xuefeng luo Fuliang He Min yuan wei liu Yong wang Hongjie Hu Xiaoli Zhu Tao yu Qinxue Sun wei qu Ting Lu Deqiang Ma li Zhang jun Ma jun yang Ketao Mu Xiaoliang Zhu Kai Xiong Huiguo Ding Shengjuan Yao Mingsheng Huang Fang wang Zexin wang Yong Huang jianan li Hongfeng Yi Birun Huang Zhongwei Zhao Duiping Feng yanming Lei Changlong Hou Wenbo Guo Shirong liu Gaojun Teng Kangshun Zhu Fan wu Xiaogang Hu Wenfeng Zhang Shaoqi yang Zhouchao Hu Pengfei Pang Shaowu Zhuang weidong wang Qingliang Zhu Kunpeng Zhang Chengyu liu Dongliang li Chao Ma Hong jiang Xingong Zhao weixin Ren Zhiwei wang Lei yu Fuhuang lin Chaoguang yan Feng wang Lei yu Hui Huan Wenyong Shen Shaofei He Chengda Zhang Jinlun Bao jiangtao liu jun wu jianbo Zhao jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina Department of Interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina Department of Intervention Taiyuan Third People's HospitalTaiyuanShanxiChina Department of Intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina Department of Interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic Intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina Department of Intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina Department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina Department of Intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina Department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina Department of Intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina Department of Interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in China in ***:We investigated the overall status of HVPG technology in China-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in China used HVPG technology in 2022 distributed across 29 provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2022,of which 2813 cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2327.9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82/87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in China and confirmed that some medical institutions in China have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai wujun Cai Yijian Cai Yizhou Cai yuchen Cai haiying Cai Huacheng Cai Lorenzo Calibbi junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De sio Elisa Del Core Shuangxue Deng wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding siqin Dingl Yadong Ding haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu Kaitengsifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)

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signal Transduction and Targeted Therapy 2023年第3期8卷 1198-1207页

作者： hai-Dong Zhu hai-liang li Ming-Sheng Huang wei-Zhu yang Guo-Wen Yin Bin-yan Zhong jun-Hui Sun Zhi-Cheng Jin jian-jian Chen Nai-jian Ge Wen-Bin Ding Wen-Hui li Jin-Hua Huang wei Mu Shan-Zhi Gu Jia-Ping li Hui Zhao Shu-wei Wen yan-Ming Lei yu-Sheng Song Chun-wang yuan wei-Dong wang Ming Huang wei Zhao jian-Bing wu Song wang Xu Zhu jian-jun Han wei-Xin Ren Zai-Ming Lu Wen-Ge Xing Yong Fan hai-Lan lin Zi-Shu Zhang Guo-Hui Xu Wen-Hao Hu qiang Tu Hong-Ying Su Chuan-Sheng Zheng Yong Chen Xu-Ya Zhao Zhu-Ting Fang Qi wang Jin-wei Zhao Ai-Bing Xu jian Xu Qing-Hua wu Huan-Zhang Niu jian wang Feng Dai Dui-Ping Feng Qing-Dong li Rong-Shu Shi Jia-Rui li Guang yang hai-Bin Shi jian-Song Ji yu-E liu Zheng Cai Po yang yang Zhao Xiao-li Zhu li-Gong Lu Gao-jun Teng Center of Interventional Radiology&Vascular Surgery Department of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009China Department of Minimally invasive Intervention The Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450008China Department of Interventional Radiology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630China Department of Interventional Radiology Union Hospital of Fujian Medical UniversityFuzhou 350001China Department of Interventional Radiology Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009China Department of Interventional Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Interventional Radiology Eastern Hospital of Hepatobiliary SurgeryNavy Medical University(Second Military Medical University)Shanghai 200438China Department of Interventional Radiology Nantong First People’s HospitalNantong 226001China Department of Interventional Radiology Yancheng Third People’s HospitalYancheng 224008China Department of Minimally Invasive Interventional Therapy Sun YatSen University Cancer CenterGuangzhou 510060China Department of Vascular Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China. Department of Interventional Radiology Hunan Cancer HospitalChangsha 410031China Department of Interventional Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Department of Interventional Radiology The Hospital of Nantong UniversityNantong 226001China Department of Interventional Therapy Shanxi Tumor HospitalTaiyuan 030001China Department of Interventional Radiology Tibet Autonomous Region People’s

There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE combined with PD-(L)1 inhibitors and MTT in real-world *** this nationwide,retrospective,cohort study,826 HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(combination group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2018 to May *** primary endpoint was progression-free survival(PFS)according to modified *** secondary outcomes included overall survival(OS),objective response rate(ORR),and *** performed propensity score matching approaches to reduce bias between two *** matching,228 pairs were included with a predominantly advanced disease *** PFS in combination group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002).OS and ORR were also significantly higher in combination group(median OS,19.2[16.1-27.3]vs.15.7 months[13.0-20.2];adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;Psignificantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile.

关键词： hepatocellular targeted matching

Eight new quasars discovered by the Guoshoujing Telescope (LAMOST) in one extragalactic field

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Research in Astronomy and Astrophysics 2010年第8期10卷 745-752页

作者： Xue-Bing wu Zhen-Dong Jia Zhao-yu Chen Wen-Wen Zuo Yong-Heng Zhao A-li luo Zhong-Rui Bai jian-jun Chen Hao-Tong Zhang Hong-liang yan Juan-Juan Ren Shi-wei Sun Hong wu Yong Zhang Ye-Ping li Qi-Shuai Lu You wang Ji-jun Ni hai wang Xu Kong Shi-Yin Shen Department of Astronomy Peking University Beijing 100871 China National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China National Institute of Astronomical Optics ＆ Technology Chinese Academy of Sciences Nanjing 210042 China Center for Astrophysics University of Science ＆ Technology of China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China

We report the discovery of eight new quasars in one extragalactic field （a five-degree field centered at RA=08^h58^m08.2^s, Dec=01°32′29.7″） with the Guoshoujing Telescope （LAMOST） commissioning observations made on 2009 December 18. These quasars, with i magnitudes from 16.44 to 19.34 and redshifts from 0.898 to 2.773, were not identified in the SDSS spectroscopic survey, though six of them with redshifts less than 2.5 were selected as quasar targets in SDSS. Except for one source without near-IR Y-band data, seven of these eight new quasars satisfy a newly proposed quasar selection criterion involving both near-IR and optical colors. Two of them were found in the ＇redshift desert＇ for quasars （z from 2.2 to 3）, indicating that the new criterion is efficient for uncovering missing quasars with similar optical colors to stars. Although LAMOST encountered some problems during the commissioning observations, we were still able to identify 38 other known SDSS quasars in this field, with i magnitudes from 16.24 to 19.10 and redshifts from 0.297 to 4.512. Our identifications imply that a substantial fraction of quasars may be miss- ing in previous quasar surveys. The implication of our results to the future LAMOST quasar survey is discussed.

关键词： quasars general -- quasars emission lines -- galaxies active

A very bright (i=16.44) quasar in the ‘redshift desert’ discovered by the Guoshoujing Telescope (LAMOST)

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Research in Astronomy and Astrophysics 2010年第8期10卷 737-744页

作者： Xue-Bing wu Zhao-yu Chen Zhen-Dong Jia Wen-Wen Zuo Yong-Heng Zhao A-li luo Zhong-Rui Bai jian-jun Chen Hao-Tong Zhang Hong-liang yan Juan-Juan Ren Shi-wei Sun Hong wu Yong Zhang Ye-Ping li Qi-Shuai Lu You wang Ji-jun Ni hai wang Xu Kong Shi-Yin Shen Department of Astronomy Peking University Beijing 100871 China National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China National Institute of Astronomical Optics ＆ Technology Chinese Academy of Science Nanjing 210042 China Center for Astrophysics University of Science ＆ Technology of China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China

The redshift range from 2.2 to 3 is known as the ＇redshift desert＇ of quasars because quasars with redshifts in this range have similar optical colors as normal stars and are thus difficult to find in optical sky surveys. A quasar candidate, SDSS J085543.40-001517.7, which was selected by a recently proposed criterion involving near-IR Y - K and optical g - z colors, was identified spectroscopically as a new quasar with a redshift of 2.427 by the Guoshoujing Telescope （LAMOST） commissioning observation in 2009 December and confirmed by the observation made with the NAOC/Xinglong 2.16 m telescope in 2010 March. This quasar was not identified in the SDSS spectroscopic survey. Comparing with other SDSS quasars, we found that this new quasar, with an i magnitude of 16.44, is apparently the brightest one in the redshift range from 2.3 to 2.7. From its spectral properties, we derived its central black hole mass to be （1.4 - 3.9） × 10^110 M⊙ and its bolometric luminosity to be 3.7 × 10^48 erg s^-1, which indicates that this new quasar is intrinsically very bright and belongs to the class of the most luminous quasars in the universe. Our identification supports the notion that quasars in the redshift desert can be found by the quasar selection criterion involving the near-IR colors. More missing quasars are expected to be uncovered by future LAMOST spectroscopic surveys, which is important to the study of the cosmological evolution of quasars at redshifts higher than 2.2.

关键词： quasars general -- quasars emission lines -- galaxies active

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li luo Yong-Heng Zhao Gang Zhao li-Cai Deng Xiao-wei liu Yi-Peng Jing Gang wang Hao-Tong Zhang jian-Rong Shi Xiang-qun Cui Yao-quan Chu Guo-Ping li Zhong-Rui Bai yue wu yan Cai Shu-yun Cao Zi-Huang Cao Jeffrey L.Carlin hai-yuan Chen jian-jun Chen Kun-Xin Chen li Chen Xue-Lei Chen Xiao-yan Chen Ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-wei Fan Lei Feng jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu yan-Xin Guo Zhan-Wen Han Bo-liang He Jin-liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei Jia Fang-Hua jiang Xiang jiang Zhi-Bo jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-Hua li Chang-Hua li Guang-wei li hai-Ning li jian li Qi li Shuang li Sha-Sha li Xin-Nan li yan li Yin-Bi li Ye-Ping li yuan liang Chien-Cheng lin Chao liu Gen-Rong liu Guan-qun liu Zhi-Gang liu Wen-Zhi Lu yu luo Yin-Dun Mao Heidi Newberg Ji-jun Ni Zhao-Xiang Qi Yong-jun Qi Shi-Yin Shen Huo-Ming Shi Jing Song Yi-Han Song Ding-qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng Tao yuan Tian Dan wang Da-Qi wang Feng-Fei wang Guo-Min wang hai wang Hong-Chi wang jian wang Jia-Ning wang jian-ling wang jian-Ping wang jun-Xian wang Lei wang Meng-Xin wang Shou-Guan wang Shu-Qing wang Xia wang Ya-Nan wang You wang yue-Fei wang You-Fen wang Peng wei Ming-Zhi wei Hong wu Ke-Fei wu Xue-Bing wu yu-Zhong wu Xiao-Zheng Xing ling-Zhe Xu Xin-Qi Xu yan Xu Tai-Sheng yan De-Hua yang hai-Feng yang Hui-Qin yang Ming yang Zheng-Qiu Yao Yong yu Hui yuan hai-Bo yuan hai-Long yuan wei-Min yuan Chao Zhai En-Peng Zhang Hua-wei Zhang jian-Nan Zhang li-Pin Zhang wei Zhang Yong Zhang yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： jun liu Dan-Dan li wei Dong yu-Qi liu yang wu Da-Xuan Tang Fu-Chun Zhang Meng Qiu Qi Hua Jing-yu He jun li Bai Du Ting-hai Du lin-lin Niu Xue-jun jiang Bo Cui jiang-Bin Chen yang-Gan wang hai-Rong wang Qin yu Jing He Yi-lin Mao Xiao-Fang Bin yue Deng yu-Dan Tian Qing-Hua Han Da-Jin liu li-Qin Duan Ming-jun Zhao Cui-Ying Zhang hai-Ying Dai Ze-Hua li Ying Xiao You-Zhi Hu Xiao-yu Huang Kun Xing Xin jiang Chao-Feng liu Jing An Feng-Chun li Tao Tao Jin-Fa jiang Ying yang Yao-Rong Dong Lei Zhang Guang Fu Ying li Shu-wei Huang li-Ping Dou Lan-jun Sun Ying-qiang Zhao Jie li yun Xia jun liu Fan liu Wen-Jin He Ying li jian-Cong Tan yang lin Ya-Bin Zhou jian-Fei yang Guo-Qing Ma Hui-jun Chen He-Ping liu Zong-wu liu jian-Xiong liu Xiao-Jia luo Xiao-Hong Bin Ya-Nan yu hai-Xia Dang Bing li Fei Teng wang-Min Qiao Xiao-Long Zhu Bing-wei Chen Qi-Guang Chen Chun-Ti Shen Yong-yan wang yun-Dai Chen Zhong wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina questionnaire(ASAQ-AF220)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF240),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

Space-to-Ground quantum Key Distribution Using a Small-sized Payload on Tiangong-2 Space Lab

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Chinese Physics Letters 2017年第9期34卷 18-23页

作者： Sheng-Kai liao Jin lin Ji-Gang Ren wei-yue liu Jia qiang Juan Yin yang li Qi Shen liang Zhang Xue-Feng liang hai-lin Yong Feng-Zhi li Ya-yun Yin yuan Cao Wen-Qi Cai Wen-Zhuo Zhang jian-jun Jia Jin-Cai wu Xiao-Wen Chen Shan-Cong Zhang Xiao-jun jiang jian-Feng wang Yong-Mei Huang qiang wang Lu Ma li li Ge-Sheng Pan qiang Zhang yu-Ao Chen Chao-yang Lu Nai-Le liu Xiongfeng Ma Rong Shu Cheng-Zhi Peng jian-yu wang jian-wei Pan Department of Modern Physics and Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of ChinaHefei 230026 Shanghai Branch CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum PhysicsShanghai 201315 Key Laboratory of Space Active Opto-Electronic Technology Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083 Beijing UCAS Space Technology Co. LtdBeijing 100190 National Astronomical Observatories Chinese Academy of SciencesBeijing 100012 Key Laboratory of Optical engineering Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209 Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011

quantum technology establishes a foundation for secure communication via quantum key distribution （QKD）. In the last two decades, the rapid development of QKD makes a global quantum communication network feasible. In order to construct this network, it is economical to consider small-sized and low-cost QKD payloads, which can be assembled on satellites with different sizes, such as space stations. Here we report an experimental demonstration of space-to-ground QKD using a small-sized payload, from Tiangong-2 space lab to Nanshan ground station. The 57.9-kg payload integrates a tracking system, a QKD transmitter along with modules for synchronization, and a laser communication transmitter. In the space lab, a 50MHz vacuum＋weak decoy-state optical source is sent through a reflective telescope with an aperture of 200mm. On the ground station, a telescope with an aperture of 1200mm collects the signal photons. A stable and high-transmittance communication channel is set up with a high-precision bidirectional tracking system, a polarization compensation module, and a synchronization system. When the quantum link is successfully established, we obtain a key rate over 100bps with a communication distance up to 719km. Together with our recent development of QKD in daylight, the present demonstration paves the way towards a practical satellite-constellation-based global quantum secure network with small-sized QKD payloads.

关键词： QKD Space-to-Ground quantum Key Distribution Using a Small-sized Payload on Tiangong-2 Space Lab

SAPT:a synchrotron-based proton therapy facility in Shanghai

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Nuclear Science and Techniques 2023年第10期34卷 36-46页

作者： Man-Zhou Zhang De-Ming li li-Ren Shen hai-Rong Zhang Zhi-ling Chen Han-Wen Du Ming Gu Rui li De-Kang liu yue-Hu Pu jun-Feng yu jian-Feng Chen Chu Chen Chun-Long Guo Hao Guo Ge-yang jiang Zhi-qiang jiang lin Jin Wen-Jing li Xiu-Fang li Ye lin Ming liu Yong-Hao liu Ya-Juan liu Ming Lv Qing-Ru Mi lian-Hua Ouyang wei-Guo Shi Hang Shu Qi-Sheng Tang Kun wang Zhi-Shan wang jun wu Xiao-Bing wu Jia-qiang Xu Wen-Zhen Xu Chong-Xian Yin Cheng yu Ren-Xian yuan Qi-Bing yuan hai-qun Zhang Miao Zhang Wen-Zhi Zhang li-Ying Zhao wei-Min Zhou Shou-Xian Fang Xi-Dong Sun Zhen-Tang Zhao Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China APACTRON Particle Equipment Co. Ltd.Shanghai 201815China The Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in *** synchrotron,beam delivery system,and other technical systems were commissioned and reached their expected *** a clinical trial of 47 patients was finished,the proton therapy facility obtained a registration certificate from the National Medical Products *** characteristics of the accelerator and treatment systems are described in this article.

关键词： Proton therapy Synchrotron Slow extraction Gantry Beam delivery system