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Mechanical Properties and Microstructure of X120 Grade High Strength Pipeline Steel

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Journal of Iron and Steel Research International 2010年第10期17卷 63-67页

作者： ZHANG Ji-ming sun wei-hua sun Hao Technology Center Jinan Steel and Iron Group Corporation Jinan 250101 Shandong China

A new ultrahigh strength pipeline steel with high yield strength and high impact toughness was fabricated in this work, and mechanical properties and microstructure of the steel were investigated. The steel exhibited out- standing mechanical properties with yield strength levels of up to 951 MPa and tensile strength levels up to 1023 MPa. The sharp notch toughness with absorbed energy values of 227 J/cm2 at -30℃ and shear area of up to 95% in drop weight tear test （DWTT） at temperature of --20℃ were achieved. It was found that microstructure of the steel com- prises a majority of low-carbon lath bainite with different sublaths and sub-sublaths, meanwhile there is a high density of dislocation between laths and the dispersed film-like martensite-austenite （M-A） constituents. Most of the precipi- tates in this steel are duplex type containing Nb and Ti with characterized morphology of cap with the range of precipitation size from a few to tens nanometers.

关键词： pipeline steel mechanical property lath bainite precipitate

Influence of Al foil interlayer on performance of vacuum diffusion bonding joint of 6061 aluminium alloy

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Journal of Iron and Steel Research International 2024年第10期31卷 2404-2412页

作者： Da-shuang Liu Jian-hua Xu Xiong-hui Li Ping wei Yun Liang Jian Qin hua-wei sun Tian-ran Ding Zong-ye Ding Su-juan Zhong Lei Zhang wei-min Long School of Material Science and Engineering Hefei University of TechnologyHefei230009AnhuiChina School of Material Science and Engineering Jiangsu University of Science and TechnologyZhenjiang212003JiangsuChina Zhengzhou Research Institute of Mechanical Engineering Co. Ltd.Zhengzhou450001HenanChina Ningbo Intelligent Machine Tool Research Institute Co. Ltd.of China National Machinery Institute GroupNingbo315700ZhejiangChina

The vacuum diffusion bonding method was used to introduce Al foil as the middle layer,and 6061 aluminium alloy was vacuum diffusion bonding *** typical microstructure characteristics and mechanical properties of 6061/Al/6061 welded joints were studied in detail,the effects of process parameters and Al intermediate layer on the microstructure and mechanical properties were revealed,and the diffusion bonding mechanism of 6061/Al/6061 welded joints was *** foil middle layer welded joint had the best performance at the temperature of 540℃,the holding time of 120 min,and the welding pressure of 4 *** bonding ratio is 95.91%,the shear strength is 79 MPa,and the deformation rate is 8.05%,and the introduction of Al intermediate layer improves the element distribution and microstructure,so that the bonding ratio of the welded joint is increased by 10.86%,the shear strength is increased by 5.55 MPa,and the deformation rate is reduced by 1.58%.The fracture morphology has typical ductile fracture characteristics.

关键词： 6061 aluminium alloy Diffusion bonding Interlayer Joint performance Elemental diffusion

CHARACTERISTIC MAGNETIC RESONANCE ENHANCEMENT PATTERN IN CEREBRAL SCHISTOSOMIASIS

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Chinese Medical Sciences Journal 2006年第4期21卷 223-227页

作者： Han-qiu Liu Xiao-yuan Feng Zhen-wei Yao hua-ping sun Department of Radiology Huashan Hospital Fudan University Shanghai 200040

Objective To describe the characteristic magnetic resonance imaging （MRI） appearance of cerebral schistosomiasis. Methods Twenty-five patients whose diagnosis of central nervous system （CNS） schistosomiasis had been pathologically （n = 8 ） and clinically （n = 17） confLrmed were randomly selected. MRI was performed on a Signal 1.5T MRI scanner before and after the intravenous administration of gadopentetate dimeghimine constrast medium. We reviewed the MRI studies obtained at the time of initial presentation, as well as follow-up studies obtained during and after medical treatment Results ImmunoLogicaL tests in L5 patients indicated schistosomiasis haematobium. Contrast-enhanced TL-weighted images in 22 cases showed central linear enhancement surrounded by multiple enhancing punctate nodules, which ap- peared “arborized”. Through operation and pathological examination, 8 cases had the granuloma formation of schistoso- mal eggs extensive surrounded by inflammation and venous congestion. And 17 cases were treated with praziquantel and corticosteroid therapy. And they were followed up for 2 months by taking MRI, which turned out to be complete resolution of the enhancing structure and edema. At follow-up, all the patients＇ initial symptoms also resolved. Conclnsion The specified MRI enhancement pattern of cerebral schistosomiasis is common in most cases of CNS schistosomiasis, so it should be taken account into the diagnosis of cerebral schistosomiasis.

关键词： cerebral schistosomiasis diagnosis magnetic resonance imaging

Effect of Substrate Characteristics on Interdiffusion Coefficients of Ni and Al Atoms in β-NiAl Phase of Aluminide Coatings

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Journal of Materials Science & Technology 2004年第2期20卷 196-198页

作者： hua wei, Xiaofeng sun, Qi ZHENG, Guichen HOU, Hengrong GUAN and Zhuangqi HUInstitute of Metal Research, The Chinese Academy of Sciences, Shenyang 110016, China Inst. of Metal Res. Chinese Acad. of Sci. Shenyang 110016 China

Interdiffusion coefficients at 950℃ and 1050℃ are calculated by Wagner analysis method as a function of composition of β-NiAI phase. The β-NiAI phase is formed by pack cementation on surface of superalloy. Results of the calculation show that interdiffusion coefficients in β-NiAI phase strongly depend on the compositions and vary over several orders of magnitude. Compared with the interdiffusion coefficients in the stoichiometric β-NiAI phase, the interdiffusion coefficients in β-NiAI phase formed on superalloy is obviously small, probably due to the composition, complicated microstructure and precipitates. However, it could be seen clearly that the shapes of the diffusivity curves are very similar to each other. The similarity of the diffusion curves and the difference between interdiffusion coefficients imply that the compositions, microstructures and precipitates of superalloy have a distinctly adverse effect on the interdiffusion of Ni and Al atoms during aluminization, but do not change the essential characteristics of β-NiAI phase.

关键词： Aluminide coating Pack cementation,β-NiAl phase Aluminization Interdiffusion coefficient

A Finite Difference Method for Determining Interdiffusivity of Aluminide Coating Formed on Superalloy

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Journal of Materials Science & Technology 2004年第5期20卷 595-598页

作者： hua wei, Xiaofeng sun, Qi ZHENG, Guichen HOU, Hengrong GUAN and Zhuangqi HUState Key Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China Lab. for Corrosion and Protection Inst. of Metal Res. Chinese Acad. of Sci. Shenyang 110016 China

A numerical method has been developed to extract the composition-dependent interdiffusivity from the concentration profiles in the aluminide coating prepared by pack cementation. The procedure is based on the classic finite difference method (FDM). In order to simplify the model, effect of some alloying elements on interdiffusivity can be negligible. Calculated results indicate the interdiffusivity in aluminide coating strongly depends on the composition and give the formulas used to calculate interdiffusivity at 850, 950 and 1050癈. The effect on interdiffusivity is briefly discussed.

关键词： Interdiffusivity Aluminide coating Finite difference method (FDM)

Identification of eight novel mutations in 11 Chinese patients with maple syrup urine disease

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World Journal of Pediatrics 2020年第4期16卷 401-410页

作者： wei-hua sun Bing-Bing Wu Ya-Qiong Wang Meng-Yuan Wu Xin-Ran Dong Yue-Ping Zhang wei Lu Ping Zhang Bin Yang Min Zhang Hong-Jiang Wu Wen-Hao Zhou Institute of Pediatrics Shanghai Key Laboratory of Birth DefectsChildren’s Hospital of Fudan UniversityWanyuan Road 399Shanghai201102China Key Laboratory of Neonatal Diseases Ministry of HealthChildren’s Hospital of Fudan UniversityShanghai201102China Department of Endocrinology Children’s Hospital of Fudan UniversityShanghai201102China Shanghai Ji-ai Genetics and IVF Institute Obstetrics and Gynecology HospitalFudan UniversityShanghai200011China Shanghai Key Laboratory of Birth Defects The Translational Medicine Center of Children Development and Disease of Fudan UniversityChildren’s Hospital of Fudan UniversityShanghai201102China Department of Radiology Children’s Hospital of ShanghaiShanghai201102China Department of Neurology Children’s Hospital of Fudan UniversityShanghai201102China

Background Maple syrup urine disease(MSUD)is an autosomal recessive inherited disorder that affects the degradation of branched-chain amino acids and is associated with acute and chronic brain *** study presents 11 new patients with MSUD and describes the clinical characteristics and gene mutations reported in Chinese *** During 2011–2018,11 pedaitric patients with MSUD from 11 Chinese families were analyzed based on clinical characteristics and mass spectrometry,with confirmation via gene *** mutations affecting protein function were predicted with Mutation-Taster,PolyPhen-2,CADD and SIFT software.3D models of the mutated proteins were generated by using the SWISS-MODEL online server,and the models were visualized in *** characteristics and gene mutations in patients with MSUD were analyzed *** Seventeen mutations in the BCKDHA,BCKDHB and DBT genes were found,8 of which are novel:c.55C>/T,c.349C>T,c.565C>T,c.808G>A,c.859C>G,and c.1270dupC in BCKDHA;c.275-2A>G in BCKDHB;and c.1291C>T in *** patients *** patients had severe mental retardation and were physically *** patient with the intermediate type had relatively good prognosis,with mild psychomotor retardation and *** mothers underwent amniocentesis for prenatal diagnosis during their second pregnancy;two fetuses were wild type,and two were carriers of one heterozygous *** Eight novel mutations were associated with MSUD in Chinese *** diagnosis was successfully performed by genetic *** in the BCKDHB gene were found in the majority of Chinese patients with MSUD.

关键词： Branched-chain amino acids Maple syrup urine disease Mutation Prenatal diagnosis

CAF-derived exosome-miR-3124-5p promotes malignant biological processes in NSCLC via the TOLLIP/TLR4-MyD88-NF-κB pathway

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Oncology Research 2025年第1期33卷 133-148页

作者： TAO sun QINGhua SONG hua LIU Department of Respiratory and Critical Care Medicine Affiliated Hospital of Nantong UniversityMedical School of Nantong UniversityNantong226001China Department of Emergency The People’s Hospital of RugaoNantong226500China Department of Haematology The People’s Hospital of RugaoNantong226500China

Background:Lung cancer is a life-threatening disease that occurs worldwide,but is especially common in *** crucial role of the tumour microenvironment(TME)in non-small cell lung cancer(NSCLC)has attracted recent ***-associated fibroblasts(CAFs)are the main factors that contribute to the TME function,and CAF exosomes are closely linked to ***:The expression levels of miR-3124-5p and Toll-interacting protein(TOLLIP)were analysed by bioinformatics prediction combined with RT-qPCR/Western Blot *** were isolated and identified from clinical NSCLC *** electron microscopy and Western Blot were used to identify exosomes from these *** in proliferation(CCK-8 and clone formation),migration(wound healing),and invasion(transwell)of NSCLC cells were *** Luciferase reporter test was applied to clarify the binding of miR-3124-5p to *** TOLLIP/TLR4/MyD88/NF-κB pathway proteins were determined using Western blot ***:MiR-3124-5p is overexpressed in clinical tissues and cells of ***-3124-5p was dramatically enriched in CAF-derived *** experiments revealed that CAFs delivered miR-3124-5p into NSCLC cells via exosomes,stimulating cancer cell ***-3124-5p acted as a sponge to negatively regulate TOLLIP expression,which activated the TLR4/MyD88/NF-κB axis to promote the occurrence and development of *** salvage tests were performed to determine whether CAF-exosome-derived miR-3124-5p plays a pro-cancer role in NSCLC by affecting the TOLLIP signalling ***:These results provide an interesting direction for the diagnosis and therapy of NSCLC.

关键词： Non-small cell lung cancer(NSCLC) Cancer-associated fibroblasts(CAFs) Exosomes miR-3124-5p Toll-interacting protein(TOLLIP)

pH和络合剂对五价锑在水钠锰矿和水铁矿表面吸附行为的影响

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环境科学 2017年第1期38卷 180-187页

作者：王华伟李晓月李卫华孙英杰青岛理工大学环境与市政工程学院青岛266033

研究了pH和络合剂对Sb(Ⅴ)在水钠锰矿和水铁矿表面吸附性能的影响.结果表明,水钠锰矿和水铁矿对Sb(Ⅴ)有良好的去除效果,初始pH显著影响水钠锰矿和水铁矿对Sb(Ⅴ)的去除效率.随着初始pH值的降低,水钠锰矿和水铁矿对Sb(Ⅴ)的去除率显著增... 详细信息

研究了pH和络合剂对Sb(Ⅴ)在水钠锰矿和水铁矿表面吸附性能的影响.结果表明,水钠锰矿和水铁矿对Sb(Ⅴ)有良好的去除效果,初始pH显著影响水钠锰矿和水铁矿对Sb(Ⅴ)的去除效率.随着初始pH值的降低,水钠锰矿和水铁矿对Sb(Ⅴ)的去除率显著增加.在初始pH 5.0时,Sb(Ⅴ)的去除率、吸附速率和吸附量要优于pH 7.0和***(Ⅴ)在水钠锰矿和水铁矿表面的吸附行为符合准二级动力学模型.在初始pH 5.0时,Langmuir模型可以较好地描述Sb(Ⅴ)在水钠锰矿和水铁矿表面的吸附过程.柠檬酸和乙二胺四乙酸(EDTA)两种络合剂显著抑制了Sb(Ⅴ)在水钠锰矿和水铁矿表面的吸附效果.

关键词：五价锑吸附行为水铁矿水钠锰矿 pH 络合剂

Effect of liquid diffusion coefficients on microstructure evolution during solidification of Al356.1 alloy

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Transactions of Nonferrous Metals Society of China 2013年第12期23卷 3722-3728页

作者：孙伟华张利军魏明杜勇黄伯云中南大学粉末冶金国家重点实验室长沙410083 中南大学中德铝合金微结构联合实验室长沙410083

（The effect of liquid diffusion coefficients on the microstructure evolution during solidification of primary （Al） phase in Al356.1 alloy was investigated by means of the phase-field simulation using two sets of diffusion coefficients in liquid phase, while fixing other thermophysical and numerical parameters. The first set is only with impurity coefficients of liquid phase in Arrhenius formula representing only the temperature dependence. While the second set is with the well-established atomic mobility database representing both temperature and concentration dependence. For the second set of liquid diffusion coefficients, the effect of non-diagonal diffusion coefficients on the microstructure evolution in Al356.1 alloy during solidification was also analyzed. The differences were observed in the morphology, tip velocity and composition profile ahead of the tip of the dendrite due to the three cases of liquid diffusivities. The simulation results indicate that accurate databases of mobilities in the liquid phase are highly needed for the quantitative simulation of microstructural evolution during solidification.

关键词： Al356.1 alloy solidification microstructure evolution diffusion coefficient phase-field simulation