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Liquid crystal display and organic light-emitting diode display: present status and future perspectives

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Light(Science & Applications) 2017年第1期6卷 77-89页

作者： hai-wei chen Jiun-Haw Lee Bo-Yen Lin Stanley chen Shin-Tson Wu College of Optics and Photonics University of Central FloridaOrlandoFL 32816USA Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering Taiwan University Nichem Fine Technology Co.Ltd.

Recently,‘Liquid crystal display(LCD)*** light-emitting diode(OLED)display:who wins?’has become a topic of heated *** this review,we perform a systematic and comparative study of these two flat panel display ***,we review recent advances in LCDs and OLEDs,including material development,device configuration and system *** we analyze and compare their performances by six key display metrics:response time,contrast ratio,color gamut,lifetime,power efficiency,and panel *** this section,we focus on two key parameters:motion picture response time(MPRT)and ambient contrast ratio(ACR),which dramatically affect image quality in practical application *** determines the image blur of a moving picture,and ACR governs the perceived image contrast under ambient lighting *** is intriguing that LCD can achieve comparable or even slightly better MPRT and ACR than OLED,although its response time and contrast ratio are generally perceived to be much inferior to those of ***,three future trends are highlighted,including high dynamic range,virtual reality/augmented reality and smart displays with versatile functions.

关键词： ambient contrast ratio liquid crystal displays motion picture response time organic light-emitting diode

2.3 μm nanosecond passive Q-switching of an LD-pumped Tm:YLF laser using gold nanorods as a saturable absorber

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Frontiers of Information Technology & Electronic Engineering 2021年第3期22卷 312-317页

作者： Fu-yan WU Shi-qiang WANG hai-wei chen hai-tao HUANG School of Physics and Electronic Engineering Jiangsu Normal UniversityXuzhou 221116China

Developing new saturable absorbers for use in the mid-infrared region has practical significance for short-pulsed lasers and related scientific and industrial *** performance of gold nanorods(GNRs)as saturable absorbers at novel mid-infrared wavelengths needs to be evaluated even though these benefit from ultrafast nonlinear responses and broadband saturable *** Q-switching of an LD-pumped 2.3μm Tm:YLF laser using GNRs was successfully realized in this *** with an 843 ns pulse width and a 6.67 kHz repetition rate were achieved using this Q-switched *** showed that GNRs provide promising passive Q-switches for 2.3μm Tm-doped lasers.

关键词： Gold nanorods Passive Q-switching 2.3μm Tm-doped laser materials

Going beyond the limit of an LCD’s color gamut

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Light(Science & Applications) 2017年第1期6卷 567-576页

作者： hai-wei chen Rui-Dong Zhu Juan He wei Duan wei Hu Yan-Qing Lu Ming-Chun Li Seok-Lyul Lee Ya-Jie Dong Shin-Tson Wu College of Optics and Photonics University of Central FloridaOrlandoFL 32816USA National Laboratory of Solid State Microstructures Collaborative Innovation Center of Advanced Microstructures and College of Engineering and Applied SciencesNanjing UniversityNanjing 210093China AU Optronics Corp NanoScience Technology Center University of Central FloridaOrlandoFL 32826USA

In this study,we analyze how a backlight’s peak wavelength,full-width at half-maximum(FWHM),and color filters affect the color gamut of a liquid crystal display(LCD)device and establish a theoretical limit,even if the FWHM approaches 1 *** overcome this limit,we propose a new backlight system incorporating a functional reflective polarizer and a patterned half-wave plate to decouple the polarization states of the blue light and the green/red *** a result,the crosstalk between three primary colors is greatly suppressed,and the color gamut is significantly *** the experiment,we prepare a white-light source using a blue light-emitting diode(LED)to pump green perovskite polymer film and red quantum dots and demonstrate an exceedingly large color gamut(95.8%Rec.2020 in Commission internationale de l'éclairage(CIE)1931 color space and 97.3%Rec.2020 in CIE 1976 color space)with commercial high-efficiency color *** results are beyond the color gamut limit achievable by a conventional *** design works equally well for other light sources,such as a 2-phosphorconverted white LED.

关键词： color gamut liquid crystal displays perovskite polarization quantum dot

Essential thrombocythemia with non-ST-segment elevation myocardial infarction as the first manifestation:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7422-7428页

作者： Zhi-Ming Wang wei-hai chen Yan-Ming Wu Lin-Quan Wang Fu-Long Ye Ren-Lin Yin Department of Cardiology Suzhou Ninth People's HospitalSoochow UniversitySuzhou 215200Jiangsu ProvinceChina

BACKGROUND We report a case of essential thrombocythemia(ET)in a 44-year-old male who exhibited non-ST-segment-elevation myocardial infarction(NSTEMI)as the first manifestation without known cardiovascular risk factors(CVRFs).For the first time,we reported a left main trifurcation lesion in NSTEMI caused by ET,including continuous stenosis lesions from the left main to the ostial left anterior descending(LAD)artery and an obvious thrombotic lesion in the ostial and proximal left circumflex(LCX)*** was 60%diffuse stenosis in the left main(LM)that extended to the ostial LAD,thrombosis of the ostial LAD and proximal LCX,and 90%stenosis in the proximal *** the operation,thrombus aspiration was performed,but no obvious thrombus was *** the kissing balloon technique(KBT)in the LCX and LM unexpectedly increased the narrowness of the ***,the single-stent crossover technique,final kissing balloon technique and proximal optimization technique(POT)were *** the second day after percutaneous coronary intervention(PCI),the number of platelets(PLTs)still increased significantly to as high as 696×10^(9)/*** bone marrow biopsy done later,together with JAK2(exon 14)V617F mutation,confirms the diagnosis of *** was administered to inhibit bone marrow proliferation to control the number of *** SUMMARY A 44-year-old male patient went to a local hospital for treatment for intermittent chest pain occurring over 8 *** examination at the local hospital revealed elevated cTnI and significantly elevated ***,he was diagnosed with acute myocardial infarction and transferred to our hospital for emergency interventional treatment by *** the operation,thrombus aspiration,the single-stent crossover technique,final kissing balloon technique and POT were *** antiplatelet therapy comprising aspirin and ticagrelor was used after *** of mutated JAK2 V617F and bone marrow biopsy shown the onset o

关键词： Essential thrombocythemia Non-ST-segment-elevation myocardial infarction Percutaneous coronary intervention Hydroxyurea Case report

Identification of CNS neural circuitry involved in the innervation of C7 spinal nerve： a viral transsynaptic tracing study

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Chinese Journal of Traumatology 2011年第5期14卷 259-263页

作者： wei hai-feng chen Liang GU Yu-dong Department of Orthopaedic Surgery Shanghai Sixth People＇s Hospital Shanghai Jiaotong University Shanghai 200233 China

Objective： Contralateral C7 spinal nerve transfer is a useful operation for the treatment of brachial plexus root avulsion. The recovery of the independent function at the ipsilateral side, however, depends on neural circuitry reorganization in the central nervous system （CNS）.This study tried to locate the CNS neuronal elements involved in the innervation ofC7 spinal ***： Pseudorabies virus （PRV, TK/gG-,2 μl）, which expressed green fluorescent protein （GFP）, was injected into the left C7 spinal nerve in 20 adult Sprague Dawley *** rats survived for 6 h, 12 h, 24 h and 36 h, the C1-C7segments of the spinal cord and brain were processed using a polyclonal immunohistochemical antibody against ***： PRV-labeled neurons were found mainly in gray matter of the C1-C7 segments of the spinal cord and at the following structures of the brain： lateral vestibular nucleus, lateral paragigantocellular nucleus, A5 cells, red nucleus, primary and secondary motor cortexes, primary and secondary somatosensory cortexes. Although located bilaterally, the PRV-labeled neurons existed predominantly in the ipsilateral side of the spinal cord and the contralateral side of the brain at 6-12 h after injection （p.i.）. The number of PRV-labeled neurons in the CNS was increasing with rat＇s survival time and the distribution of these neurons turned bilateral with no obvious dominance to either side at 24 h and 36 h （p.i.）.Conclusion： By use of transsynaptic tracing technique with PRV, the anatomically connected set of neurons,which modulates the activity of C7 spinal nerve, is located successfully in the CNS.

关键词： Brachial plexus Innervation Spinal nerves Central nervous system

Biomedical polymers: synthesis, properties, and applications

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Science China Chemistry 2022年第6期65卷 1010-1075页

作者： wei-hai chen Qi-Wen chen Qian chen Chunyan Cui Shun Duan Yongyuan Kang Yang Liu Yun Liu Wali Muhammad Shiqun Shao chengqiang Tang Jinqiang Wang Lei Wang Meng-Hua Xiong Lichen Yin Kuo Zhang Zhanzhan Zhang Xu Zhen Jun Feng Changyou Gao Zhen Gu Chaoliang He Jian Ji Xiqun Jiang Wenguang Liu Zhuang Liu Huisheng Peng Youqing Shen Linqi Shi Xuemei Sun Hao Wang Jun Wang haihua Xiao Fu-Jian Xu Zhiyuan Zhong Xian-Zheng Zhang Xuesi chen Key Laboratory of Biomedical Polymers of Ministry of Education&Department of Chemistry Wuhan UniversityWuhan430072China Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou215123China School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin300350China Key Laboratory of Biomedical Materials of Natural Macromolecules(Beijing University of Chemical Technology) Ministry of EducationBeijing Laboratory of Biomedical MaterialsCollege of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing100029China MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou310027China State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of EducationCollege of ChemistryNankai UniversityTianjin300071China Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China Jinhua Institute of Zhejiang University Jinhua321299China Zhejiang Key Laboratory of Smart BioMaterials and Center for Bionanoengineering College of Chemical and Biological EngineeringZhejiang UniversityHangzhou310027China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou311215China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science and Laboratory of Advanced MaterialsFudan UniversityShanghai200438China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nano-scienceNational Center for Nanoscience and Technology(NCNST)Beijing100190China School of Biomedical Sciences and Engineering Guangzhou International CampusSouth China University of TechnologyGuangzhou510006China Institute of Functional Nano and So

Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.

关键词： biomedical polymer nanomedicine cancer therapy drug delivery bioimaging and biosensing tissue engineering regenerative medicine cytotoxicity biocompatibility

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng wei Tan Xingxing chen Shuyuan Bai Qiong Wu Yushan chen Zhen wei Yufei Mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 498-503页

作者： Liang Chu Haoyu Shen Hudie wei Hongyu chen Guoqiang Ma Wensheng Yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector

Effects of tumor necrosis factor-alpha on calcium movement in rat ventricular myocytes

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Acta Pharmacologica Sinica 2003年第12期 50-56页

作者： LI Xiao-Qiang, ZHAO Ming-Gao, MEI Qi-Bing~2, ZHANG Yan-Feng CAO wei, WANG hai-Fang, chen Dan~3, CUI Yi Department of Pharmacology, ~3Electron Microscopy Center, The Fourth Military Medical University, Xi-an 710032, China

AIM: To study the effects of tumor necrosis factor-alpha (TNF-α) on calcium movement in rat ventricular myocytes. METHODS: Intracellular free Ca2+concentration was measured with calcium fluorescent probe Fluo-3/AM and laser confocal microscope. L-type calcium current (ICa.L) was recorded with the whole-cell configuration of the patch-clamp techniques. RESULTS: At 2, 20 and 200μg/L, TNF-α was found to increase intracellular free Ca2+concentration in a dose-dependent manner illustrated by the increment of calcium fluorescence density with laser confocal microscope. Nicardipine 0.5μtmol/L slightly attenuated TNF-α-induced response. When the cardiac myocytes were exposed to caffeine (100mmol/L) for 30 rain, TNF-α failed to induce any change of intracellular free calcium. However, it was found that TNF-α inhibited *** whole-cell patch-clamp experiments. At 2, 20, and 200μg/L, TNF-α decreased peak *** 3.9％ (-5.1 pA/pF±0.3 pA/pF vs -4.9 pA/pF±0.2 pA/pF, n=9, P>0.05), 15.7

关键词： tumor necrosis factor myocardium calcium: patch-clamp techniques confocal microscopy