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Perinatal prevalence of birth defects in the Mainland of China,2000–2021:a systematic review and meta-analysis

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World Journal of Pediatrics 2024年第7期20卷 669-681页

作者： Liang-Yu Kang Zi-Rui guo wei-Jing Shang Gui-ying Cao yi-Ping Zhang Qiao-Mei Wang Hai-Ping Shen Wan-Nian Liang Min Liu Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityNo.38Xueyuan RoadHaidian DistrictBeijing100191China Vanke School of Public Health Tsinghua UniversityNo.1Tsinghua GardenHaidian DistrictBeijing100084China Department of Maternal and Child Health National Health Commission of the People’s Republic of ChinaNo.1Xizhimenwai South RoadXicheng DistrictBeijingChina Institute of Healthy China Tsinghua UniversityNo.1Tsinghua GardenHaidian DistrictBeijing100084China Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of Education BeijingNo.38Xueyuan RoadHaidian DistrictBeijing100191China

Background Although birth defects are of great concern globally,the latest national prevalence has not yet been quantified in *** conducted a systematic review and meta-analysis to estimate the perinatal prevalence of birth defects in the Mainland of China between 2000 and *** We performed a systematic literature search of six databases for relevant articles published between January 1,2000,and March 1,*** included published studies that reported data on the perinatal prevalence of birth defects in the Mainland of *** DerSimonian and Laird random-effects models were used to estimate the pooled prevalence and its 95%confidence interval(CI).We also conducted subgroup analyses and univariable meta-regressions to explore differences in prevalence by time period,geographic region,and other *** We included 254 studies reporting the perinatal prevalence of birth defects and 86 studies reporting only the prevalence of specific types of birth *** on 254 studies covering 74,307,037 perinatal births and 985,115 cases with birth defects,the pooled perinatal prevalence of birth defects was 122.54(95%CI 116.20–128.89)per 10,000 perinatal births in the Mainland of China during 2000–***,the perinatal prevalence of birth defects increased from 95.60(86.51–104.69)per 10,000 in 2000–2004 to 208.94(175.67–242.22)per 10,000 in 2020–*** were also significant disparities among different geographical *** heart defects(33.35 per 10,000),clefts of the lip and/or palate(13.52 per 10,000),polydactyly(12.82 per 10,000),neural tube defects(12.82 per 10,000),and inborn errors of metabolism(11.41 per 10,000)were the five most common types of birth *** perinatal prevalence among males was significantly higher than that among females(β=2.44×10^(−3),P=0.003);a higher perinatal prevalence of birth defects was observed among perinatal births whose mothers were≥35 years(β=4.34×10^(−3),P<0.001).Conclusion Compreh

关键词： Birth defects China Perinatal Prevalence

Graph Convolutional Networks Embedding Textual Structure Information for Relation Extraction

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Computers, Materials & Continua 2024年第5期79卷 3299-3314页

作者： Chuyuan wei Jinzhe Li Zhiyuan Wang Shanshan Wan Maozu guo School of Electrical and Information Engineering Beijing University of Civil Engineering and ArchitectureBeijing102616China

Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,sentiment analysis and question-answering ***,previous studies ignored much unusedstructural information in sentences that could enhance the performance of the relation extraction ***,most existing dependency-based models utilize self-attention to distinguish the importance of context,whichhardly deals withmultiple-structure *** efficiently leverage multiple structure information,this paperproposes a dynamic structure attention mechanism model based on textual structure information,which deeplyintegrates word embedding,named entity recognition labels,part of speech,dependency tree and dependency typeinto a graph convolutional ***,our model extracts text features of different structures from theinput *** Structure information Graph Convolutional Networks employs the dynamic structureattention mechanism to learn multi-structure attention,effectively distinguishing important contextual features invarious structural *** addition,multi-structure weights are carefully designed as amergingmechanismin the different structure attention to dynamically adjust the final *** paper combines these featuresand trains a graph convolutional network for relation *** experiment on supervised relation extractiondatasets including SemEval 2010 Task 8,TACRED,TACREV,and Re-TACED,the result significantly outperformsthe previous.

关键词： Relation extraction graph convolutional neural networks dependency tree dynamic structure attention

Path Planning for AUVs Based on Improved APF-AC Algorithm

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Computers, Materials & Continua 2024年第3期78卷 3721-3741页

作者： guojun Chen Danguo Cheng wei Chen Xue Yang Tiezheng guo Industrial Center Nanjing Institute of TechnologyNanjing211167China

With the increase in ocean exploration activities and underwater development,the autonomous underwater vehicle(AUV)has been widely used as a type of underwater automation equipment in the detection of underwater ***,nowadays AUVs generally have drawbacks such as weak endurance,low intelligence,and poor detection *** research and implementation of path-planning methods are the premise of AUVs to achieve actual *** improve the underwater operation ability of the AUV,this paper studies the typical problems of path-planning for the ant colony algorithm and the artificial potential field *** response to the limitations of a single algorithm,an optimization scheme is proposed to improve the artificial potential field ant colony(APF-AC)*** with traditional ant colony and comparative algorithms,the APF-AC reduced the path length by 1.57%and 0.63%(in the simple environment),8.92%and 3.46%(in the complex environment).The iteration time has been reduced by approximately 28.48%and 18.05%(in the simple environment),18.53%and 9.24%(in the complex environment).Finally,the improved APF-AC algorithm has been validated on the AUV platform,and the experiment is consistent with the *** APF-AC algorithm can effectively reduce the underwater operation time and overall power consumption of the AUV,and shows a higher safety.

关键词： Path-planning autonomous underwater vehicle ant colony algorithm artificial potential field bio-inspired neural network

Broadband and fabrication-tolerant 3-dB couplers with topological valley edge modes

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Light(Science & Applications) 2024年第8期13卷 1623-1630页

作者： guo-Jing Tang Xiao-Dong Chen Lu Sun Chao-Heng guo Meng-Yu Li Zhong-Tao Tian Hou-Hong Chen Hong-wei Wang Qi-Yao Sun ying-Di Pan Xin-Tao He yi-Kai Su Jian-Wen Dong School of Physics&State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Advanced Optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong UniversityShanghai 200240China

3-dB couplers,which are commonly used in photonic integrated circuits for on-chip information processing,precision measurement,and quantum computing,face challenges in achieving robust performance due to their limited 3-dB bandwidths and sensitivity to fabrication *** address this,we introduce topological physics to nanophotonics,developing a framework for topological 3-dB *** couplers exhibit broad working wavelength range and robustness against fabrication dimensional *** leveraging valley-Hall topology and mirror symmetry,the photonic-crystal-slab couplers achieve ideal 3-dB splitting characterized by a wavelength-insensitive scattering *** analysis confirms the superiority on broad bandwidth of 48 nm and robust splitting against dimensional errors of 20 *** further propose a topological interferometer for on-chip distance measurement,which also exhibits robustness against dimensional *** extension of topological principles to the fields of interferometers,may open up new possibilities for constructing robust wavelength division multiplexing,temperature-drift-insensitive sensing,and optical coherence tomography applications.

关键词： topological splitting insensitive

Metal-Free Synthesis of 2-Aminobenzothiazoles via I2-Catalyzed Tandem Cyclization Reaction of Amines and Carbon Disulfide

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Chinese Journal of Chemistry 2024年第8期42卷 846-852页

作者： Ting Chen wei Feng Ruitong Yang Shanping Chen guo-Jun Deng Key Laboratory for Green Organic Synthesis and Application of Hunan Province Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of EducationCollege of ChemistryXiangtan UniversityXiangtanHunan411105 China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiangHunan453007 China

Comprehensive Summary,A convenient approach for the construction of 2-aminobenzothiazoles via I2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been *** present approach starts from simple and readily available starting materials,affording a series of 2-aminobenzothiazoles in up to 89%yields under metal-free *** this work,C—H/N—H functionalization was achieved and multiple C-hetero bonds were successfully constructed in one pot.

关键词： Sulfur heterocycles C-H functionalization Cyclization Tandem reaction Transition-metal-free Amines lodine N-Heterocycles

Development characteristics and controlling factors of fractures in lacustrine shale and their geological significance for evaluating shale oil sweet spots in the third member of the Shahejie Formation in the Qikou Sag, Bohai Bay Basin

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Petroleum Science 2024年第2期21卷 791-805页

作者： Xu Zeng Tao Yang Jian-wei Feng Cong-Sheng Bian Ming Guan wei Liu Bing-Cheng guo Jin Dong Research Institute of Petroleum Exploration and Development China National Petroleum CorporationBeijing100083China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China School of Earth Sciences China University of PetroleumQingdao266400ShandongChina

Natural fractures are critical for shale oil and gas enrichment and development. Due to the extremely high heterogeneity of shale, the factors controlling the formation of internal fractures, especially horizontal fractures, remain controversial. In this study, we integrate thin section analysis and microcomputed tomography(CT) data from several lacustrine shale samples from the third member(Es3) of the Shahejie Formation, Qikou Sag, Bohai Bay Basin, to assess the fractures in detail. The goal is to reveal the development characteristics, controlling factors, and geological significance for evaluating sweet spots in a shale oil play. The fractures in the Es3contain high-angle structural and horizontal bed-parallel fractures that are mostly shear and extensional. Various factors influence fracture development,including lithofacies, mineral composition, organic matter content, and the number of laminae. Structural fractures occur predominantly in siltstone, whereas bed-parallel fractures are abundant in laminated shale and layered mudstone. A higher quartz content results in higher shale brittleness, causing fractures, whereas the transformation between clay minerals contributes to the development of bedparallel fractures. Excess pore pressure due to hydrocarbon generation and expulsion during thermal advance can cause the formation of bed-parallel fractures. The density of the bed-parallel and structural fractures increases with the lamina density, and the bed-parallel fractures are more sensitive to the number of laminae. The fractures are critical storage spaces and flow conduits and are indicative of sweet spots. The laminated shale in the Es3with a high organic matter content contains natural fractures and is an organic-rich, liquid-rich, self-sourced shale play. Conversely, the siltstone, massive mudstone, and argillaceous carbonate lithofacies contain lower amounts of organic matter and do not have bed-parallel fractures. However, good reservoirs can form in th

关键词： Fractures Development characteristics Controlling factors Shale oil Sweet spot

SMEC:Scene Mining for E-Commerce

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Journal of Computer Science & Technology 2024年第1期39卷 192-210页

作者：王罡李翔郭子义殷大伟马帅 State Key Laboratory of Software Development Environment Beihang UniversityBeijing 100191China School of Data Science and Engineering East China Normal UniversityShanghai 200062China *** Inc.Beijing 100176China Baidu Inc.Beijing 100085China

Scene-based recommendation has proven its usefulness in E-commerce,by recommending commodities based on a given ***,scenes are typically unknown in advance,which necessitates scene discovery for *** this article,we study scene discovery for E-commerce *** first formalize a scene as a set of commodity cate-gories that occur simultaneously and frequently in real-world situations,and model an E-commerce platform as a heteroge-neous information network(HIN),whose nodes and links represent different types of objects and different types of rela-tionships between objects,*** then formulate the scene mining problem for E-commerce as an unsupervised learning problem that finds the overlapping clusters of commodity categories in the *** solve the problem,we pro-pose a non-negative matrix factorization based method SMEC(Scene Mining for E-Commerce),and theoretically prove its *** six real-world E-commerce datasets,we finally conduct an extensive experimental study to evaluate SMEC against 13 other methods,and show that SMEC consistently outperforms its competitors with regard to various evaluation measures.

关键词： graph clustering E-commerce heterogeneous information network(HIN) scene mining

PbrARF4 contributes to calyx shedding of fruitlets in ‘Dangshan Suli’ pear by partly regulating the expression of abscission genes

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Horticultural Plant Journal 2024年第2期10卷 341-354页

作者： guoling guo Pengfei wei Tao Yu Haiyan Zhang wei Heng Lun Liu Liwu Zhu Bing Jia School of Horticulture Anhui Agricultural UniversityHefeiAnhui 230036China Huayuan Foreign Language School Zhejiang Normal UniversityJinhuaZhejiang 322100China Agricultural Experimental Center of Guiyang Guiyang Agriculture and Rural BureauGuiyangGuizhou 550018China

Fruitlet calyx shedding in pear plants is apparently regulated via numerous pathways that involve both environmental triggers and phytohormones cues such as auxin. In this study, we found at 10 days after full bloom (DAFB) higher levels of indoleacetic acid (IAA) and tryptophan (Trp) in calyx persistence fruitlet (CPF) than calyx shedding fruitlet (CSF) ofDanshan Suli’ pear (Pyrus bretschneideri Rhed.). Consisting with this, the activity of indolealdehyde oxidase (IAAIdO), which promotes IAA synthesis, was remarkably increased, and that of peroxidase(POD), which degrades IAA, dropped markedly in CPF but not in CSF. Further, qRT-PCR results revealed that most of 31 PbrARFs (encoding auxin response factors) in Pyrus bretschneideri were highly expressed in CPF, whereas PbrARF4, PbrARF24 and PbrARF26 were significantly downregulated in CPF vis-a-vis CSF. Phylogenetic analysis revealed that 6 PbrARFs clustered in the group III, where PbrARF4 showed the closest affinity with AtARF1 that promotes organ abscission, indicating a putative role of PbrARF4 in mediating the process of calyx shedding in pear. In fact, the ectopic overexpression of PbrARF4 in Solanum lycopersicum resulted in an earlier-formed and deeper abscission layer (AL) in the transgenic plants, whose calyxes were more prone to wilt at the mature red stage (MR) compared with the control plants (wild-type). More importantly, expression levels of the abscission genes SILS and Sl Cel2 in transgenic plants overexpressing PbrARF4 were significantly upregulated in comparation with the WT, whereas those of Sl BI and Sl TAPG2 were considerably inhibited. Further, PbrJOINTLESS and PbrIDA,the two genes related to calyx shedding in pear, were up-regulated more in CSF than CPF. The findings contribute to a better understanding of PbrARFs involved in fruitlet calyx shedding of pear, which could prove beneficial to improving the quality of pear fruit.

关键词： Pear Pyrus bretschneideri Rehd Calyx shedding IAA PbrARF4 Abscission genes

Microstructural evolution,mechanical properties and degradation mechanism of PS-PVD quasi-columnar thermal barrier coatings exposed to glassy CMAS deposits

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Rare Metals 2024年第7期43卷 3329-3340页

作者： Zi-Yue Yu Liang-Liang wei Xing-Ye guo Bao-Peng Zhang Qing He Hong-Bo guo School of Materials Science and Engineering Beihang UniversityBeijing100191China Key Laboratory of High-Temperature Structure Materials and Protective Coatings(Ministry of Industry and Information Technology) Beihang UniversityBeijing 100191China Surface Engineering Research Institute Chinese Academy of Agricultural Mechanization SciencesBeijing 100083China

Thermal barrier coatings(TBCs) applied in aeroengines tend to be attacked by molten calcia-magnesiaalumino-silicate(CMAS) at high operating ***-stabilized zirconia(YSZ) coatings with quasicolumnar microstructure were fabricated by plasma spray physical vapor deposition(PS-PVD) *** chemic al changes,micros tructural transform ation,mechanical properties and degradation mechanisms of the CM AS-interacted TBCs in the thermal cycling tests were *** YSZ grains were dissolved in the CMAS melts,and then the ZrO_(2) grains were reprecipitated with spherical shape,accompanying with phase transformation from tetragonal(t) to monoclinic(m).The thermal cycling tests reveal that the YSZ coating fails at the early stage due to the attack of *** fractures in intracolumns lead to partial spallation of the *** failure of the coating occurs at the interfaces between thermally grown oxides(TGO) layer and YSZ topcoat;especially,the hardness and Young's modulus of the YSZ coatings increase intensively,as the coatings were infiltrated by the CMAS for a long time.

关键词： CMAS Thermal barrier coatings Young's modulus Thermal cycling behavior PS-PVD