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Chinese Journal of Traumatology 2020年第6期23卷 356-362页

作者： wei peng Na Bi Jun Zheng Na Xi Eighth Medical Center of Chinese PLA General Hospital Beijing 100091China

Purpose By comparing the outcomes of total hip arthroplasty with hemiarthroplasty in elderly patients with a femoral neck fracture to investigate the one-year mortality,dislocation,infection,reoperation rate,and thromboembolic *** The PubMed,EMBASE databases,and Cochrane library were systematically searched from the inception dates to April 1,2020 for relevant randomized controlled trials in English language using the keywords:“total hip arthroplasty”,“hemiarthroplasty”and“femoral neck fracture”to identify systematic reviews and *** reviewers independently selected articles,extracted data,assessed the quality evidence and risk bias of included trials using the Cochrane Collaboration’stools,and discussed any *** third reviewer was consulted for any doubts or *** derived risk ratios and 95%confidence *** was defined as the primary *** outcomes were other complications,dislocation,infection,reoperation rate,and thromboembolic *** This meta-analysis included 10 studies with 1419 patients,which indicated that there were no significant differences between hemiarthroplasty and total hip arthroplasty in reoperation,infection rate,and thromboembolic ***,there was a lower mortality and dislocation rate association with total hip arthroplasty at the one-year *** Based on our results,we found that total hip arthroplasty was better than hemiarthroplasty for a hip fracture at one-year follow-up.

关键词： Total hip arthroplasty Hemiarthroplasty Femoral neck fractures Meta-analysis

Effect of tempering on bonding characteristics of cross wedge rolling 42CrMo/Q235 laminated shafts

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Journal of Iron and Steel Research International 2020年第10期27卷 1170-1178页

作者： Shuai Zhu Wen-fei peng Xue-dao Shu Zhejiang Provincial Key Laboratory of Part Rolling Technology Ningbo UniversityNingbo 315211ZhejiangChina

To further improve the comprehensive properties of 42CrMo/Q235 laminated shafts produced by cross wedge *** treatment of the shafts was *** and bending tests were carried out to compare the changes in mechanicalproperties before and after heat *** results showed that the interfacial bonding strength increased most aftertempering at 350℃for 45 *** microstructure of the interface was observed using a digital *** resultsshowed that the dispersed oxides on the interface were basically eliminated by using the scheme of tempering at 350 cand holding for 45 *** reasons for the change in mechanical properties were explained from the point of theinterfacial *** electron microscopy was used to analyze the micro-morphology of the tensile *** was observed that after tempering at 350℃and holding for 45 min,the dimple holes became larger and deeper,and thestructure of fracture became more uniform and *** the point of the tensile fracture *** reasons for thechange in mcchanical propcrties wcrc explained as well.

关键词： Heat treatment Cross wedge rolling Interface Microstructure Fracture morphology

加快建设金融强国的内涵要义、逻辑衔接与实践路径

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经济学家 2024年第2期 60-70页

作者：魏鹏中国工商银行牡丹卡中心

金融是国民经济的血脉,是国家核心竞争力的重要组成部分。金融强国建设既包括金融生产力发展,又包括金融生产关系变革,旨在实现传统金融服务方式向现代金融服务方式转变,最终构建起金融领导强、金融实力强、金融服务强、金融供给强、金... 详细信息

金融是国民经济的血脉,是国家核心竞争力的重要组成部分。金融强国建设既包括金融生产力发展,又包括金融生产关系变革,旨在实现传统金融服务方式向现代金融服务方式转变,最终构建起金融领导强、金融实力强、金融服务强、金融供给强、金融监管强、金融开放强、金融安全强的中国特色现代金融体系。金融强国建设不是孤立的,而是与开拓中国特色金融发展之路、推动金融高质量发展、构建社会主义现代化强国密切相关的。为高质量推进金融强国建设,应当坚持党的全面领导和党中央集中统一领导,加强党对思想政治建设、公司治理、经营管理的领导;完善现代金融监管体系,坚定不移走中国特色金融发展之路;守住金融风险底线,有效防范化解金融风险;做细做实5篇大文章,支持中国式现代化建设。

关键词：金融强国中国特色金融发展之路中国特色现代金融体系金融高质量发展

Research on the Factors of Asset Prices in the Inflation Mechanism

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学术界 2014年第4期 278-282页

作者： Liu peng School of Economics Beijing University Beijing 100871

With the acceleration of economic globalization and financial liberalization,factors of asset prices such as stock,bond and real estate and so on become important economic variables that affect inflation. After a brief review of the latest literature,this paper analyzes the specific conduction mechanism from different aspects of consumption,investment,credit and exchange rate channels in which asset prices affect inflation. Then,this paper analyzes the monthly data from January,2002 to December,2013 with the PLS method(partial least squares regression method)and discusses whether a structural change has taken place in the inflation mechanism during this period. Finally,policy recommendations are provided.

关键词：传导机制影响因素价格资产偏最小二乘回归法经济全球化偏最小二乘法数据分析

Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer： a retrospective clinical experience from a Chinese medical centre

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Asian Journal of Andrology 2010年第5期12卷 718-727页

作者： Xue-Qin Chen Ying Huang Xiang Li peng Zhang Rui Huang Juan Xia Ni Chen Qiang wei Yu-Chun Zhu Yu-Ru Yang Hao Zeng Laboratory and Department of Pathology West China Hospital Sichuan University Chengdu 610041 China Department of Urology West China Hospital Sichuan University Chengdu 610041 China Department of Nuclear Medicine West China Hospital Sichuan University Chengdu 610041 China

In this retrospective study, we evaluated and compared the efficacy and toxicities of maximal androgen blockade （MAB） versus castration alone in Chinese patients with advanced prostate cancer. From 1996 to 2004, 608 patients with advanced prostate cancer were included in the study. Patients were retrospectively divided into two groups according to different therapeutic regimens. Of the 608 patients, 300 patients were treated with MAB （castration plus nonsteroidal antiandrogens） and the remaining 308 were treated with castration alone. The 2- and 5-year overall survival rates of these patients were 73.7% and 56%, respectively. Multivariate analysis showed that, in patients with metastatic prostate cancer, MAB was associated with not only the improvement of progression-free survival （PFS）（increased by 10 months） but also a 20.6% reduction in mortality risk compared with castration alone. In contrast, the efficacy of MAB was not superior to castration alone for patients with nonmetastatic prostate cancer. Interestingly, among patients with MAB, those using bicalutamide had a longer PFS than those using flutamide; this was especially so in patients with metastatic prostate cancer. Almost all of the toxicities due to the hormone therapy were mild to moderate and manageable. To conclude, in China, hormone therapies, including MAB and castration alone, have been standard treatments for advanced prostate cancer. For patients with nonmetastatic prostate cancer, castration alone might be adequately practical and efficient. In patients with metastatic prostate cancer, however, MAB has superior efficacy over castration alone. It is clear that MAB should be considered the first-line standard treatment for patients with metastatic prostate cancer.

关键词： bicalutamide castration alone maximal androgen blockade prostate cancer

Characterization of hot deformation behavior of AA2014 forging aluminum alloy using processing map

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Transactions of Nonferrous Metals Society of China 2017年第8期27卷 1677-1688页

作者： peng-wei LI Hui-zhong LI Lan HUANG Xiao-peng LIANG Ze-xiao ZHU School of Materials Science and Engineering Central South University Changsha 410083 China Key Laboratory of Nonferrous Metal Materials Science and Engineering Ministry of Education Central South University Changsha 410083 China State Key Laboratory of Powder Metallurgy Central South University Changsha 410083 China

The hot deformation behavior of AA2014forging aluminum alloy was investigated by isothermal compression tests attemperatures of350-480°C and strain rates of0.001-1s-1on a *** corresponding microstructures of thealloys under different deformation conditions were studied using optical microscopy(OM),electron back scattered diffraction(EBSD)and transmission electron microscopy(TEM).The processing maps were constructed with strains of0.1,0.3,*** results showed that the instability domain was more inclined to occur at strain rates higher than0.1s-1and manifested in theform of local non-uniform *** the strain of0.7,the processing map showed two stability domains:domain I(350-430°C,0.005-0.1s-1)and domain II(450-480°C,0.001-0.05s-1).The predominant softening mechanisms in both of the twodomains were dynamic *** microstructures were obtained in domain I,and an extended recovery occurred in domainII,which would lead to the potential sub-grain boundaries progressively transforming into new high-angle grain *** hot working parameters for the AA2014forging aluminum alloy were determined to be370-420°C and0.008-0.08s-1.

关键词： AA2014 aluminum alloy hot deformation behavior constitutive model processing map softening mechanism

Nonlinear Optical Absorption in Polydiacetylene Crystal

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Chinese Physics Letters 1993年第2期10卷 115-118页

作者： peng Jingcui Department of Applied Physics Hu’nan UniversityChangsha 410082

In this paper,the nonlinear optical absorption under two input optical waves is *** nonlinear absorption coefficient is derived,and numerical results are calculated,which agree with experimental results.

关键词： absorption nonlinear Nonlinear

Antiproliferation and apoptosis induction of paeonol in HepG_2 cells

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World Journal of Gastroenterology 2007年第2期13卷 250-256页

作者： Shu-Ping Xu Guo-Ping Sun Yu-Xian Shen wei wei Wan-Ren peng Hua Wang Institute of Clinical Pharmacology of Anhni Medical University Key Laboratory of Antiinflammatory and Immunological Pharmacology in Anhui Province Key Laboratory of Research and Development of Chinese Medicine of Anhui province Hefei 230032 Anhui Province. China Department of Oncology The First Affiliated Hospital of Anhui Medical University Hefei 230022 Anhui Province China Department of Oncology Provincial Hospital of Anhui Hefei 230001 Anhui Province China

AIM： To investigate the antiproliferative effect of paeonol （Pae） used alone or in combination with chemotherapeutic agents [cisplatin （CDDP）, doxorubicin （DOX） and 5-fluorouracil （5-FU）] on human hepatoma cell line HepG2 and the possible mechanisms. METHODS： The cytotoxic effect of drugs on HepG2 cells was measured by 3-（4, 5-dimethylthiazol-2- yl）-2, 5-diphenyltetra-zolium bromide （MTT） assay. Morphologic changes were observed by acridine orange （AO） fuorescence staining. Cell cycle and apoptosis rate were detected by flow cytometry （FCM）. Drug-drug interactions were analyzed by the coefficient of drug RESULTS： Pae （7.81-250 mg/L） had an inhibitory effect on the proliferation of HepG2 cells in a dose-dependent manner, with the IC50 value of （104.77±7.28） mg/L. AO fluorescence staining and FCM assays showed that Pae induced apoptosis and arrested cell cycle at S phase in HepG2 cells. Further, different extent synergisms were observed when Pae （15.63, 31.25, 62.5 rag/L） was combined with CDDP （0.31-2.5 mg/L）, DOX （0.16-1.25 mg/L）, or 5-FU （12.5-100 mg/L） at appropriate concentrations. The IC50 value of the three drugs decreased dramatically when combined with Pae （P 〈 0.01）. Of the three different combinations, the sensitivity of cells to drugs was considerably ***： Pae had a significant growth-inhibitory effect on the human hepatoma cell line HepG2, which may be related to apoptosis induction and cell cycle arrest. It also can enhance the cytotoxicity of chemotherapeutic agents on HepG2 cells, and the S phase arrest induced by Pae may be one of the mechanisms of these interactions.

关键词： Paeonol Hepatocellular carcinoma Apoptosis Cell cycle Cisplatin Doxorubicin 5-fluorouracil Synergistic effect

Sedative and Hypnotic Effects and Transcriptome Analysis of Polygala tenuifolia in Aged Insomnia Rats

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Chinese Journal of Integrative Medicine 2020年第6期26卷 434-441页

作者： REN Xiao-juan WANG Guan-ying ZHANG Xing-ping WANG Qing-quan peng Zhi-peng Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University Urumqi(830000)China Department of Gerontology Xinjiang Urumqi Municipality Traditional Chinese Medicine HospitalUrumqi(830002)China

Objective:To study the sedative and hypnotic effects and underlying mechanisms of Polygala tenuifolia(PT)on treating aged insomnia ***:Sixty Sprague-Dawley male rats were divided into 6 groups by a random number table,including control group,model group,diazepam group(0.92 mg/kg),as well as PT low-,medium-and high-dose groups(0.0875,0.175,0.35 g/kg,respectively),10 rats in each *** insomnia rat model was established with subcutaneous injection of D-galactose for 42 days and then intraperitoneal injection of para-chlorophenylalanine for 3 *** and diazepam were respectively given to aged insomnia rats by intragastric administration for 7 days after model *** the rats were investigated by body weight,Morris water maze test,pentobarbital test,enzyme-linked immunosorbent assay,and transcriptome ***:Compared with the model group,PT increased the body weight,improved memory ability,and prolonged pentobarbital-induced sleep time of aged insomnia rats(P<0.01 or P<0.05).The medium dose of PT also increased the neurotransmitter levels of 5-hydroxytryptamine(5-HT)and gamma-aminobutyric acid(GABA),and decreased the level of Glu in the hippocampus of aged insomnia rats(P<0.05 or P<0.01).Twenty-four differentially expressed genes(DEGs)were overlapped among model group,medium-dose PT group,and diazepam group in transcriptome *** and Pcp2 were down-regulated by the treatment of medium-dose PT(P<0.01 or P<0.05).The metabolic pathways of PT were relatively less than diazepam(91 vs.104).Conclusions:The sedative and hypnotic effects of PT in aged insomnia rats might be related to neuro,metabolism pathways,especially through GABAergic signaling *** provided more effective herb choice for the treatment of senile insomnia.

关键词： Polygala tenuifolia Chinese medicine aged insomnia sedative and hypnotic effects molecular mechanism

A Neural Network Recognition Method of Shape Pattern

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Journal of Iron and Steel Research International 2001年第1期8卷 16-20页

作者： peng Yan LIU Hong-min Yanshan University

A new pattern recognition method of shape was presented based on artificial neural network *** method avoids the defects of shape pattern recognition with polynomials and it has strong disturbance *** has been proved to be superior in recognizing different shape patterns by identifying many sorts of working sample books which the results are known.

关键词： shape pattern recognition artificial neural networ