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Effects of Hydroxyethyl Starch 130/0.4 Pretreatment on Endotoxin-InducedAcute Lung Injury in Rats

麻醉与监护论坛 2010年第3期17卷 174-179页

作者： wei zhang cai fang jun ma yan-hu xie juan li Department of Anesthesiology Affiliated Anhui Provincial Hospital of Anhui Medical University Hefei 230001 China

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Chinese expert consensus on the management of hypertension in the very elderly

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Journal of Geriatric Cardiology 2016年第12期13卷 945-953页

作者： Jing li Yi-Xin hu Wen WANG Ning-Yuan fang Xin-Zheng LU lin PI Mei-lin liU wei-Min li yan-fang li Peng QU Qi huA Qing HE Hai-Ying WU Yuan-Ming zhang Xiao-Ping CHEN Lu-Yuan CHEN li FAN Xing-Sheng ZHAO Zhi-Ming Zhu Yi-Nong JIANG Yi-fang GUO Hong YUAN Ping-Jin GAO Xin-juan XU jun cai liang-Di xie Xuan Wu Hospital Capital Medical University Beijing China Chinese PLA General Hospital Beijing China Chinese Academy of Medical Science Fuwai Hospital Beijing China Renji Hospital Medical College of Shanghai Jiao Tong University ShanghaL China Jiang Su Province People's Hospital Jiangsu China Beijing Chui yang liu Hospital Beijing China Peking University First Hospital Beijing China First Affiliated Hospital of Harbin Medical University Heilongjiang China Beijing An Zhen Hospital Capital Medical University Beijing China The Second Affiliated Hospital of Dalian Medical University Liaoning China Beijing Hospital Beijing China The First Hospital of Xinjiang Medical University Xinjiang Uygur Autonomous Region China West China Hospital Sichuan University Sichuan China The People's Hospital of Guangdong Province Guangdong China Inner Mongolia Autonomous Region People's Hospital Inner Mongolia Autonomous Region China Daping Hospital the Third Military Medical University Chongqing China The First Affiliated Hospital of Dalian Medical University Liaoning China Hebei Province People's Hospital Hebei China Xiangya Third Hospital Central South University Hunan China Shanghai Hypertension Research Institute Shanghai China The First Hospital of Fujian Medical University Fujian China

Population aging has become a major challenge for the healthcare in China. More than 23 million Chinese are cur- rently ≥ 80 years, with an annual increase of 5%. The Chi- nese population of 80 years or older is expe... 详细信息

关键词： Consensus Geriatric Hypertension Octogenarians

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Guideline for the diagnosis and treatment of rheumatoid arthritis with integrated traditional Chinese medicine and Western medicine to increase efficiency and reduce toxicity

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Traditional Medicine Research 2023年第3期8卷 19-35页

作者： Zhi-jun xie wei Cao lin huang yang-Qin Xun Nan yang Ping Wang Qiao Wang Meng-juan Ren Hai-Chang li Yun-Lan liu Yu-jun Tang Yue hu hui Zheng juan-juan zhang hui Lan Shou-Yuan Wu Qiang-Qiang Guo Ya-Jia Sun Xian-Zhuo zhang Xiao-hui Wang Xu-Ping Song yan-fang ma Yao-Long Chen Cheng-Ping Wen Basic Medical School Zhejiang Chinese Medical UniversityHangzhou 310053China Department of Rheumatology Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China Center for Evidence-Based Medicine School of Basic MedicineLanzhou UniversityLanzhou 730000China School of Public Health Lanzhou UniversityLanzhou 730000China The Institutes of Biology and Medical Sciences Soochow UniversitySuzhou 215123China The First Clinical Medical College Lanzhou UniversityLanzhou 730000China Hong Kong Chinese Medicine Clinical Study Center School of Chinese MedicineHong Kong Baptist UniversityHong Kong SARChina Institute of Health Data Science Lanzhou UniversityLanzhou 730000China Research Unit of Evidence-Based Evaluation and Guidelines(2021RU017) Chinese Academy of Medical SciencesSchool of Basic Medical SciencesLanzhou UniversityLanzhou 730000China WHO Collaborating Centre for Guideline Implementation and Knowledge Translation Lanzhou 730000China

Rheumatoid arthritis imposes a huge disease *** practice guidelines do not meet the needs of integrated traditional Chinese medicine and Western medicine in the treatment of rheumatoid *** established a guideline working group consists of a steering committee,a secretary group,an evidence evaluation group,a consensus group and a review group and developed a guideline following the guidance of the World Health Organization Handbook and the Chinese Medical *** guideline includes 35 recommendations which reached consensus by the two rounds Delphi *** recommendations were formulated to address the following themes of most concern to clinician:diagnostic imaging,disease staging,traditional Chinese medicine syndromes,effectiveness and toxicity of integrated traditional Chinese medicine and Western medicine.

关键词： rheumatoid arthritis guideline traditional Chinese medicine toxicity

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The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients

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Science China(life Sciences) 2016年第9期59卷 930-939,938-939+932-937页

作者： Jin liu lingling Bian li Ji yang Chen Heng Chen Yong Gu Bingqin ma wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua ma hui Jin Xing Shi Heng Miao Bing Xin yan Zhu Zhenwen zhang Ruifang Bu Lan Xu Guangde Shi wei Tang wei li Dongmei Zhou jun liang Xingbo Cheng Bimin Shi Jixiang Dong Ji hu Chen fang Shao Zhong weinan Yu weiping Lu Chenguang Wu li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun xie Minmin An wei zhang Zhixiao Wang Yun cai Qi Fu Yu Fu Shuai Zheng Fan yang Qingfang hu Hao Dai Yu Jin Zheng zhang Kuanfeng Xu Yifan li Jie Shen Hongwen Zhou wei He Xuqin Zheng Xiao Han liping Yu Jinxiong She Mei zhang Tao yang Department of Endocrinology and Metabolism First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China Barbara Davis Center for Childhood Diabetes University of Colorado Denver Aurora Colorado 80045 USA Key Laboratory of human Functional Genomics of Jiangsu Province Nanjing Medical University Nanjing 210000 China Department of Isotopic Laboratory of Nanjing Medical University Nanjing 210000 China HLA Laboratory of Jiangsu Province People's Hospital Nanjing 210029 China Department of Endocrinology and Metabolism Nanjing General Hospital of Nanjing Military Command Nanjing 210002 China Department of Endocrinology and Metabolism Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Nanjing 210008 China Department of Endocrinology and Metabolism Zhongda Hospital Southeast University Nanjing 210009 China Department of Endocrinology and Metabolism Nanjing First Hospital Nanjing 210000 China Department of Endocrinology and Metabolism Nanjing Children's Hospital Nanfing 210008 China Department of Endocrinology and Metabolism The Second Affiliated Hospital of Nanjing Medical University Nanjing 210011 China Department of Endocrinology and Metabolism Nanjing Governmental Hospital Nanjing 210008 China Department of Endocrinology and Metabolism Northern Jiangsu People's Hospital Yangzhou 225001 China Department of Endocrinology and Metabolism Wuxi People's Hospital Wuxi 214023 China Department of Endocrinology and Metabolism Jiangsu Jiangyin People's Hospital Wuxi 214400 China Department of Endocrinology and Metabolism The Affiliated Hospital of Xuzhou Medical College Xuzhou 221006 China Department of Endocrinology and Metabolism Xuzhou Central Hospital Xuzhou 221009 China Department of Endocrinology and Metabolism The First Affiliated Hospital of Soochow University Suzhou 215006 China Department of Endocrinology and Metabolism The Second Affiliated Hospital of Soochow University Suzhou 215004 China Department of Endocri

Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.

关键词： autoantibodies heterogeneity islet failure type 1 diabetes

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Delivery room resuscitation and short-term outcomes of extremely preterm and extremely low birth weight infants: a multicenter survey in North China

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Chinese Medical Journal 2021年第13期134卷 1561-1568页

作者： Shuai-jun li Qi Feng Xiu-Ying Tian Ying Zhou Yong Ji Yue-Mei li Shu-Fen Zhai wei Guo fang zhang Rong-Xiu Zheng Hai-Ying He Xia liu jun-Yi Wang hua Mei Hong-Yun Wang hua xie Chao-Mei Zeng li ma Ping-Ping zhang Jin-Yu li Xiao-Ying Wang li-hua li Hong Cui Shu-Lan yang Lu Chen Xiao-Hong Gu yan-Ju hu Sheng-Shun Que li-Xia Sun Ming yang Wen-li Zhao Qiu-yan ma Hai-juan Wang Jiu-Ye Guo Department of Pediatrics Peking University First HospitalBeijing 100034China Department of Neonatology Tianjin Central Hospital of Gynecology ObstetricsTianjin 300100China Department of Pediatrics Peking University Third HospitalBeijing 100191China Neonatal Intensive Care Unit Children's Hospital of ShanxiTaiyuanShanxi 030031China Department of Neonatology The Second Hospital of Hebei Medical UniversityShijiazhuangHebei 050000China Department of Neonatology Handan Central HospitalHandanHebei 056004China Department of Neonatology Xingtai People's HospitalXingtaiHebei 054031China Department of Neonatology Tangshan Maternal and Child Health HospitalTangshanHebei 071023China Department of Pediatrics Tianjin Medical University General HospitalTianjin 300052China Department of Pediatrics Baogang Third Hospital of HongCi GroupBaotouInner Mongolia Autonomous Region 014010China Department of Neonatology Affiliated Hospital of Chengde Medical UniversityChengdeHebei 067000China Department of Pediatrics The First Hospital of Tsinghua UniversityBeijing 100016China Department of Neonatology The Affiliated Hospital of Inner Mongolia Medical UniversityHohhotInner Mongolia Autonomous Region 010050China Department of Neonatology Inner Mongolia Maternal and Child Health HospitalHohhotInner Mongolia Autonomous Region 010020China Department of Neonatology Affiliated Hospital of Chifeng UniversityChifengInner Mongolia Autonomous Region 024005China Department of Pediatrics Peking University People's HospitalBeijing 100044China Department of Neonatology Hebei Children's HospitalShijiazhuangHebei 050000China Department of Neonatology Tianjin First Central HospitalTianjin 300384China Department of Pediatrics Peking Union Medical College HospitalBeijing 100730China Department of Neonatology Children's Hospital Capital Institute of PediatricsBeijing 100020China Department of Pediatrics Beijing Luhe Hospital.Capital Medical UniversityBeijing 101149China Department of Pediatrics Beijing Fri

Background:Delivery room resuscitation assists preterm infants,especially extremely preterm infants(EPI)and extremely low birth weight infants(ELBWI),in breathing support,while it potentially exerts a negative impact on the lungs and outcomes of preterm *** study aimed to assess delivery room resuscitation and discharge outcomes of EPI and ELBWI in ***:The clinical data of EPI(gestational age[GA]weight[BW]mary outcomes were delivery room resuscitation and risk factors for delivery room intubation(DRI).The secondary outcomes were survival rates,incidence of bronchopulmonary dysplasia(BPD),and risk factors for ***:A cohort of 952 preterm infants were *** incidence of DRI,chest compressions,and administration of epinephrine was 55.9%(532/952),12.5%(119/952),and 7.0%(67/952),*** analysis revealed that the risk factors for DRI were GAmale(OR,1.603;95% CI,1.061–2.424),DRI(OR,2.094;95% CI,1.328–3.303),respiratory distress syndrome exposed to≥2 doses of pulmonary surfactants(PS;OR,2.700;95%CI,1.679–4.343),and mechanical ventilation≥7 days(OR,4.358;95% CI,2.777–6.837).However,a larger BW(OR,0.998;95% CI,0.996–0.999),antenatal steroid(OR,0.577;95%CI,0.379–0.880),and PS use in the delivery room(OR,0.273;95%CI,0.160–0.467)were preventive factors for BPD(all Plivery room resuscitation and management of respiratory complications are imperative during early management of the health of EPI and

关键词： Extremely preterm Extremely low birth weight infants Delivery room resuscitation Survival rate BPD Risk factors

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Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China:focus on the safety

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Infectious Diseases of Poverty 2021年第2期10卷 75-76页

作者： Jing-Tao Gao juan Du Gui-hui Wu Yi Pei Meng-Qiu Gao Leonardo martinez lin Fan wei Chen li xie Yu Chen hua Wang Long Jin Guo-Bao li Pei-Lan Zong Yu Xiong Qian-Hong Wu Ming-Wu li Xiao-Feng yan yan-fang Miao Qing-Shan cai Xin-Jie li Da-Peng Bai Shu-jun Geng Guo-li yang Pei-junTang Yi Zeng Xiao-Hong Chen Tong-Xia li Cui cai Yun Zhou ma Zhuo Jian-Yun Wang Wen-Long Guan lin Xu Ji-Chan Shi wei Shu li-li Cheng FeiTeng Yu-Jia Ning Shi-Heng xie Yu-Xian Sun li-Jie zhang Yu-Hong liu Clinical Center on TB Beijing Chest HospitalCapital Medical University/Beijing Tuberculosis and Thoracic Tum or Research InstituteNo 9Beiguan StreetTongzhou DistrictBeijing 101149Peopled Republic of China 不详

Background:World Health Organization recommends countries introducing new drug and short treatment regimen for drug resistant tuberculosis(DR-TB)should develop and implement a system for active pharmacovigilance that allows for detection,reporting and management of adverse *** aim of the study is to evaluate the frequency and severity of adverse events(AEs)of bedaquiline-containing regimen in a cohort of Chinese patients with multidrug-resistant(MDR)/extensively drug-resistant(XDR)-TB based on active drug safety monitoring(aDSM)system of New Drug Introduction and Protection Program(NDIP).

关键词： Tuberculosis Multidrug-resistant Bedaquiline Safety Surveillance program China

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基于个体化机器学习的原发性免疫性血小板减少症危重出血预测模型:一项全国前瞻性队列研究

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Science Bulletin 2023年第18期68卷 2106-2114,M0004页

作者： Zhuo-Yu An Ye-jun Wu Yu Hou Heng Mei wei-Xia Nong Wen-Qian li hu Zhou Ru Feng Jian-Ping Shen jun Peng Hai Zhou Yi liu Yong-Ping Song lin-hua yang Mei-Yun fang Jian-Yong li Yun-Feng Cheng Peng liu Ya-Jing Xu Zhao Wang Yi Luo Zhen cai hui liu Jing-Wen Wang juan li Xi zhang Zi-Min Sun Xiao-Yu Zhu Xin Wang Rong Fu liang huang Shao-Yuan Wang Tong-hua yang li-Ping Su liang-Ming ma xie-Qun Chen Dai-Hong liu Hong-Xia Yao Jia Feng Hong-Yu zhang Ming Jiang Ze-Ping Zhou Wen-Sheng Wang Xu-liang Shen yangjin Baima Yue-Ying li Qian-Fei Wang Qiu-Sha huang Hai-Xia Fu Xiao-Lu Zhu Yun He Qian Jiang Hao Jiang Jin Lu Xiang-Yu Zhao Ying-jun Chang Tao Wu Yao-Zhu Pan lin Qiu Da Gao A-Rong Jin wei li Su-jun Gao Lei zhang Ming Hou Xiao-jun huang Xiao-hui zhang on behalf of the National Cooperative ITP Working Group Peking University People’s Hospital Peking University Institute of HematologyBeijing 100044China Collaborative Innovation Center of Hematology Peking UniversityBeijing 100044China Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation Beijing 100044China National Clinical Research Center for Hematologic Disease Beijing 100044China Department of Hematology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250014China Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Department of Hematology First Affiliated HospitalSchool of MedicineShihezi UniversityShihezi 832002China Department of Hematology Qinghai Provincial People’s HospitalXining 810007China Henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou UniversityHenan Institute of HematologyZhengzhou 450008China Department of Hematology Beijing HospitalBeijing 100044China Department of Hematology Zhejiang Provincial Hospital of Traditional Chinese MedicineHangzhou 310006China Department of Hematology Senior Department of Hematologythe Fifth Medical Center of PLA General HospitalBeijing 100044China Department of Hematology the Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of Hematology Affiliated Zhongshan Hospital of Dalian UniversityDalian 116001China Department of Hematology The First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital)Nanjing 210029China Department of Hematology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Hematology Xiangya HospitalCentral South UniversityChangsha 410008China Department of Hematology Beijing Friendship HospitalCapital Medical UniversityBeijing 100044China Institute of Hematology the First Affiliated HospitalZhejiang UniversityHangzhou 310058China Department of Hematology Beijing Tongren HospitalBeijing 100005China Department of Hematology The First Affiliated HospitalSun Yat-sen UniversityGuang

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者... 详细信息

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者致命出血事件的预测模型。本研究首次采用国际血栓与止血学会新提出的ITP致命出血标准,利用大样本数据开发了首个基于机器学习的在线应用,用于预测ITP患者的致命出血.研究中,我们使用中国各地大型多中心数据进行开发,并对全国39家医疗中心进行为期一年的外部测试,得到了较好的训练、验证和测试数据集预测能力该基于新算法的便捷网络工具能够快速识别ITP患者的出血风险,辅助临床决策,有望未来降低不良事件的发生。

关键词： Critical bleeding Severe bleeding Immune thrombocytopenia machine learning Prediction model

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Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen yan-Fen Chai Xiao-hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-wei Cheng Bang-Han Ding yang Deng Jie Fu Bang-Jiang fang mai-Ying Fan li Gui Ping Gong wei Guo Shu-Bin Guo liang huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-cai Ji Hong-Xu Jin Xin-jun Jiang Wang-Xiang Jiang Jia-liang liu Xiao-Ran liu Zhi liu Chuan-Zhu Lv Feng Lu Tan-Shi li Xin li Yong li Shang-Lun li Shuang-Ming li Xiao-Gang li Bao-jun li Pei-Wu li Chun-Sheng li Zhi-jun li Chang-Luo li Xiang-Min li Yin-Ping li Zong-jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian Luo Xiao-Xing liao Jian-Bo Lei Tao ma Yu ma Yue-Feng ma Qing-Bian ma lin-Hao ma jun-Qi ma Shi-Nan Nie Jie-Miao Ou-yang Peng Peng Qiao Pei Shu-Ming Pan Guo-Zhong Qing li-Jie Qin Wu-Ying Qiao Fei Shao wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-juan Sha Gui-Lan Tao Guo-Gang Tian Ying-Ping Tian Jian-Guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao Wang Xin Wang Peng Wang Zhong Wang Tong Wang Ri-Xing Wang Yi-Xin Wang Xiao-Dan Wang ling Wu wei wei hua Xiang Feng Xu jun Xu Jie Xu Miao-Rong xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi li-Shan yang Shi-Jiao yan Jin-Jian Yao Shou-Chun yan Xue-Zhong Yu Xian-Zhi Ye Xian-liang yan Fu-Bing Zhou Rong-Bin Zhou Ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu hua-Dong Zhu Ji-Hong Zhu Hong zhang mao zhang hua zhang Na zhang Guo-Qiang zhang Guo-Xiu zhang Jin-Song zhang Wen-Wu zhang Wen-Zhong zhang Jian-Feng zhang Yi-Min Zhu jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao yan Zhao Min Zhao Bin Zhao Xiao-Dong Zhao Xiao-Jing Zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

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Feasibility and physics potential of detecting ^(8)B solar neutrinos at junO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano max Buesken mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao cai Xiao cai yanke cai Zhiyan cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can fang Jian fang marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani maxim Gonchar Guanghua Gong hui Gong Oleg Gorchakov Yuri Gornushkin marco Grassi Christian Grewing maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han yan Yerevan Physics Institute YerevanArmenia Universitélibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(junO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of junO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of junO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),junO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,junO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino junO

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert maarten Boonekamp marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua cai Wenyong cai Wujun cai Yijian cai Yizhou cai Yuchen cai Haiying cai huacheng cai Lorenzo Calibbi junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen hua-Xing Chen huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhu&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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