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Sedimentary Characterization of the Upper Paleozoic Coal-Bearing Tight Sand Strata, Daniudi Gas Field, Ordos Basin, China

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Journal of Earth Science 2016年第5期27卷 823-834页

作者： wei du Zaixing Jiang Qing Li Ying Zhang Petroleum Exploration and Production Research Institute of SINOPEC Beijing 100083 China College of Energy China University of Geosciences Beijing 100083 China Research Institute of Petroleum Exploration and Development Petro China Beijing 100083 China

The coal-bearing strata of the Upper Paleozoic（from the Taiyuan Formation to the lower member of the Shanxi Formation） are the most important units that have high gas production in the Daniudi gas field, which is a typical tight-sandstone reservoir with high heterogeneity in the Ordos Basin, China. Based on an integrated investigation of well logs, cores, SEM and 3-D seismic data, we delineated the sedimentary facies of the coal-bearing strata and divided the succession into sequenced stratigraphic units of different depositional systems. A sedimentary hiatus was documented for the first time in the study area and forms the sequence boundary between the Lower Pennsylvanian Carboniferous Taiyuan Formation（Ct1） and the Upper Pennsylvanian Carboniferous Taiyuan Formation（Ct2）. The coal-bearing strata in Ct1 are indicative of a barrier coastal deposition system. Tidal channels are identified by their fine-grained, cross-stratified character. The sands in the tidal channels are well sorted, and the quartz content is above 95%. The coalbed located beside the sandstone is thought to be a lagoon. Gas-bearing, coarse-grained sandstone in the coal-bearing strata spanning from the Ct2 to the lower members of the Shanxi Formation（P1s） is interpreted as a fluvial-dominated braided delta that is divided into four third-order sequences. The coal-bearing strata are composed of sandstone, mudstone and coalbed from base to top in each sequence. Braided-river deposits form the lowstand system tract（LST） within each sequence. A shelf and lake depositional environment containing dark gray mudstone forms the transgressive systems tract（TST）. The highstand systems tract（HST） deposits form the swamp coalbed in each sequence.

关键词： sedimentary characterization depositional system Ordos Basin highstand systemtract.

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冷却液物性参数对柴油机缸盖冷却性能的影响

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车用发动机 2024年第1期 28-36页

作者：向红林杜巍北京理工大学机械与车辆学院北京100081

为探索发动机冷却液各物性参数对发动机冷却性能的影响规律,针对某大功率柴油发动机气缸盖,在通过台架试验验证仿真计算的准确性和可靠性的基础上,利用数值模拟、相关性分析和回归分析确定了冷却液密度、比热容、导热系数和沸点对气缸... 详细信息

为探索发动机冷却液各物性参数对发动机冷却性能的影响规律,针对某大功率柴油发动机气缸盖,在通过台架试验验证仿真计算的准确性和可靠性的基础上,利用数值模拟、相关性分析和回归分析确定了冷却液密度、比热容、导热系数和沸点对气缸盖水套表面最高温度、火力面最高温度、冷却液进出水口温差和缸盖内气体体积的影响规律、影响显著程度及拟合关系式,同时对比了50%体积浓度乙二醇水溶液和水的冷却效果。结果表明:水套表面最高温度、火力面最高温度均与密度、比热容、导热系数成正相关,与沸点成负相关,前者受沸点和导热系数影响较大,后者受沸点影响较大;进出水口温差与密度、比热容、沸点成负相关,与导热系数成正相关,且其受比热容影响较大;气体体积与4个物性参数均成负相关,其受比热容和沸点影响最大。由回归分析得出了水套表面最高温度、火力面最高温度、进出水口温差和气体体积关系式,各关系式误差分别在1%,0.5%,10%和30%以内。另外,在同等条件下,水的冷却效果比50%体积浓度的乙二醇水溶液的冷却效果好。

关键词：冷却液物性参数气缸盖冷却性能相关性分析回归分析

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Spatial and Temporal Distributions and Sources of Anthropogenic NMVOCs in the Atmosphere of China:A Review

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Advances in Atmospheric Sciences 2021年第7期38卷 1085-1100页

作者： Fanglin WANG wei du Shaojun LV Zhijian DING Gehui WANG Key Lab of Geographic Information Science of the Ministry of Education School of Geographic SciencesEast China Normal UniversityShanghai 200241China Institute of Eco-Chongming Shanghai 200062China

As the key precursors of O_(3),anthropogenic non-methane volatile organic compounds(NMVOCs)have been studied intensively.This paper performed a meta-analysis on the spatial and temporal variations of NMVOCs,their roles in photochemical reactions,and their sources in China,based on published research.The results showed that both nonmethane hydrocarbons(NMHCs)and oxygenated VOCs(OVOCs)in China have higher mixing ratios in the eastern developed cities compared to those in the central and western areas.Alkanes are the most abundant NMHCs species in all reported sites while formaldehyde is the most abundant among the OVOCs.OVOCs have the highest mixing ratios in summer and the lowest in winter,which is opposite to NMHCs.Among all NMVOCs,the top eight species account for 50%−70%of the total ozone formation potential(OFP)with different compositions and contributions in different areas.In devolved regions,OFP-NMHCs are the highest in winter while OFP-OVOCs are the highest in summer.Based on positive matrix factorization(PMF)analysis,vehicle exhaust,industrial emissions,and solvent usage in China are the main sources for NMHCs.However,the emission trend analysis showed that solvent usage and industrial emissions will exceed vehicle exhaust and become the two major sources of NMVOCs in near future.Based on the meta-analysis conducted in this work,we believe that the spatio-temporal variations and oxidation mechanisms of atmospheric OVOCs,as well as generating a higher spatial resolution of emission inventories of NMVOCs represent an area for future studies on NMVOCs in China.

关键词： NMVOCs spatial-temporal distribution photochemical activity source analysis

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X-Paste improves wound healing in diabetes via NF-E2-related factor/HO-1 signaling pathway

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World Journal of Diabetes 2024年第6期15卷 1299-1316页

作者： Ming-wei du Xin-Lin Zhu Dong-Xing Zhang Xian-Zhen Chen Li-Hua Yang Jin-Zhou Xiao Wen-Jie Fang Xiao-Chun Xue wei-Hua Pan Wan-Qing Liao Tao Yang Institute of Cardiovascular Disease Shanghai Key Laboratory of Traditional Chinese Clinical MedicineShanghai University of Traditional Chinese MedicineShanghai 200120China Department of Dermatology Shanghai Key Laboratory of Molecular Medical MycologySecond Affiliated Hospital of Naval Medical UniversityShanghai 200003China Department of Dermatology Dongshan HospitalMeizhou 514000Guangdong ProvinceChina Department of Dermatology Central Hospital Affiliated to Shandong First Medical UniversityJinan 250000Shandong ProvinceChina Department of Emergency Naval Hospital of Eastern TheaterZhoushan 316000Zhejiang ProvinceChina Department of Pharmacy 905th Hospital of People’s Liberation Army of China(PLA)NavyShanghai 200052China

BACKGROUND Diabetic foot ulcers(DFU),as severe complications of diabetes mellitus(DM),significantly compromise patient health and carry risks of amputation and mortality.AIM To offer new insights into the occurrence and development of DFU,focusing on the therapeutic mechanisms of X-Paste(XP)of wound healing in diabetic mice.METHODS Employing traditional Chinese medicine ointment preparation methods,XP combines various medicinal ingredients.High-performance liquid chromatography(HPLC)identified XP’s main components.Using streptozotocin(STZ)-induced diabetic,we aimed to investigate whether XP participated in the process of diabetic wound healing.RNA-sequencing analyzed gene expression differences between XP-treated and control groups.Molecular docking clarified XP’s treatment mechanisms for diabetic wound healing.Human umbilical vein endothelial cells(HUVECs)were used to investigate the effects of Andrographolide(Andro)on cell viability,reactive oxygen species generation,apoptosis,proliferation,and metastasis in vitro following exposure to high glucose(HG),while NF-E2-related factor-2(Nrf2)knockdown elucidated Andro’s molecular mechanisms.RESULTS XP notably enhanced wound healing in mice,expediting the healing process.RNA-sequencing revealed Nrf2 upregulation in DM tissues following XP treatment.HPLC identified 21 primary XP components,with Andro exhibiting strong Nrf2 binding.Andro mitigated HG-induced HUVECs proliferation,metastasis,angiogenic injury,and inflammation inhibition.Andro alleviates HG-induced HUVECs damage through Nrf2/HO-1 pathway activation,with Nrf2 knockdown reducing Andro’s proliferative and endothelial protective effects.CONCLUSION XP significantly promotes wound healing in STZ-induced diabetic models.As XP’s key component,Andro activates the Nrf2/HO-1 signaling pathway,enhancing cell proliferation,tubule formation,and inflammation reduction.

关键词： Words:Diabetes mellitus Wound healing NF-E2-related factor-2/HO-1 signaling pathway Andrographolide

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基于多时间尺度协同的大规模原油调度进化算法

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计算机应用 2024年第5期44卷 1355-1363页

作者：张莞婷杜文莉堵威能源化工过程智能制造教育部重点实验室(华东理工大学) 上海200237

针对原油调度过程存在的资源规模庞大、约束条件复杂、多时间尺度决策衔接困难等问题,提出一种基于多时间尺度协同的进化算法(MTCEA)。首先,根据炼油企业的规模结构和实际需求,建立了一种大规模多时间尺度原油调度优化模型,该模型由面... 详细信息

针对原油调度过程存在的资源规模庞大、约束条件复杂、多时间尺度决策衔接困难等问题,提出一种基于多时间尺度协同的进化算法(MTCEA)。首先,根据炼油企业的规模结构和实际需求,建立了一种大规模多时间尺度原油调度优化模型,该模型由面向资源的中长期调度模型和面向操作的短期调度模型构成,通过引入原油资源动态分组策略,实现原油资源的合理配置,以满足不同的调度规模、多时间尺度的特征和精细化生产的要求;其次,为促进不同时间尺度调度决策的融合衔接,设计基于多时间尺度协同的进化算法,并针对不同时间尺度调度模型中的连续决策变量构造子问题进行求解,以实现不同时间尺度调度决策之间的协同优化;最后,在3个实际工业案例进行了算法性能验证。结果表明,与3种具有代表性的大规模进化优化算法(即竞争性粒子群优化算法(CSO)、基于多轨迹搜索的自适应差分进化算法(SaDE-MMTS)和基于混合模型的进化策略(MMES))以及3种高性能混合整数非线性规划(MINLP)数学求解器(即ANTIGONE(Algorithms for coNTinuous/Integer Global Optimization of Nonlinear Equations)、SCIP(Solving Constraint Integer Programs)和SHOT(Supporting Hyperplane Optimization Toolkit))相比,MTCEA的求解最优性指标和稳定性指标分别提高了30%和25%以上。这些显著的性能提升验证了MTCEA在大规模多时间尺度原油调度决策中的实际应用价值和优势。

关键词：进化算法大规模优化协同优化原油调度多时间尺度

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Exploring the mechanism of action of herb pair Pinellia Ternata-Magnolia Officinalis in the treatment of liver cancer based on network pharmacology and molecular docking

Pharmacology Discovery

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Pharmacology Discovery 2024年第1期4卷 51-65页

作者： Zi-wei du Meng-wei Xu Rui Peng Min Fang Yan Liu Guang-Shuai Zhang Si Yan Li-Na Yang Shuang-Lin Qin School of Pharmacy Xianning Medical CollegeHubei University of Science and TechnologyXianning 437100China Hubei Engineering Research Center of Traditional Chinese Medicine of South Hubei Province Xianning Medical CollegeHubei University of Science and TechnologyXianning 437100China Department of Pharmacy Zhangzhou Affiliated Hospital of Fujian Medical UniversityZhangzhou 363000China

Background:Explore the anti-tumor mechanism of herb pair Pinellia ternate-Magnolia officinalis(BX-HP)in liver cancer through network pharmacology using molecular docking methods.Method:The active ingredients and corresponding targets of the herb pair Pinellia ternate-Magnolia officinalis were obtained from the HERB database.The relevant targets for liver cancer were obtained from GeneCards,DisGeNET,TTD,and Drugbank databases.Obtain common targets between herb pair Pinellia ternate-Magnolia officinalis and liver cancer through the Bioinformatics platform,establish a PPI network diagram using STRING software,and perform GO functional enrichment and KEGG pathway enrichment analysis on the DAVID platform.AutoDockTools 1.5.7 software and molecular dynamics simulation analysis are used to evaluate the binding of components to target proteins.HERB database,SwissTargetPrediction database,SwissADME database,UniProt database,GeneCards database,TTD database,DRUGBANK database,DisGeNET database,String,DAVID.Bioinformatics platform,PDB database,PubChem and TCMSP database.Result:A total of 22 active ingredients with a Probability>0.1 targets in Magnolia officinalis were screened,26 active ingredients with a Probability>0.1 targets in Pinellia ternata,ten vital active ingredients,corresponding to 979 and 803 targets with a Probability>0.1 targets,2536 liver cancer-related targets,and 279 targets in the herb pair Pinellia ternata-Magnolia officinalis.The GO functional enrichment analysis resulted in 1297 entries,namely 971 biological process entries,118 cell localization entries,and 208 molecular function entries.Three signaling pathways were annotated through the KEGG pathway.Based on molecular docking,ten vital active ingredients and five target proteins were validated to exhibit an excellent binding affinity.The above data indicates that combining the herb pair Pinellia ternata-Magnolia officinalis may treat liver cancer through specific targets and signaling pathways.Conclusion:Herb pair Pinellia ternata-Magnolia officinalis

关键词： liver cancer herb pair Pinellia ternata-Magnolia officinalis target prediction network pharmacology molecular docking mechanism

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STUDY ON THE DYNAMIC BEHAVIOR OF AXIALLY MOVING RECTANGULAR PLATES PARTIALLY SUBMERSED IN FLUID

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Acta Mechanica Solida Sinica 2015年第6期28卷 706-721页

作者： Yanqing Wang wei du Xiaobo Huang Senwen Xue Institute of Applied Mechanics Northeastern University

The natural frequencies, complex modes and critical speeds of an axially moving rectangular plate, which is partially immersed in a fluid and subjected to a pretension, are investigated. The effects of free surface waves, compressibility and viscidity of the fluid are neglected in the analysis. The subsection functions are used to describe the discontinuous characteristics of the system due to partial immersion. The classical thin plate theory is adopted to formulate the equations of motion of a vibrating plate. The velocity potential and Bernoulli＇s equation are used to describe the fluid pressure acting on the moving plate. The effect of fluid on the vibrations of the plate may be equivalent to the added mass on the plate. The effects of distance ratio, moving speed, immersed-depth ratio, boundary conditions, stiffness ratio and aspect ratio of the plate as well as the fluid-plate density ratios on the free vibrations of the moving plate-fluid system are investigated.

关键词： partially immersed axially moving rectangular plates fluid-structure interaction free vibration

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无人自主系统跨域协同作战试验初探

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火力与指挥控制 2024年第5期49卷 191-195,201页

作者：杜伟廖学军于浩航天工程大学研究生院北京101416 中国白城兵器试验中心吉林白城137001 航天工程大学航天保障系北京102206

随着战争形态由信息化向智能化转变,利用无人自主系统在多维空间实现跨域协同效能聚合成为联合作战的重要发展方向,无人自主系统跨域协同作战试验是适应战争形态发展需要应运而生的新型作战试验组织形式。梳理了无人自主系统跨域协同作... 详细信息

随着战争形态由信息化向智能化转变,利用无人自主系统在多维空间实现跨域协同效能聚合成为联合作战的重要发展方向,无人自主系统跨域协同作战试验是适应战争形态发展需要应运而生的新型作战试验组织形式。梳理了无人自主系统跨域协同作战试验鉴定的发展动态,分析了试验特点规律和试验能力需求。基于系统工程方法,从时间维、逻辑维和知识维构建了无人自主系统跨域协同作战试验系统工程的三维结构模型,为系统化、程序化、规范化开展作战试验提供参考借鉴。

关键词：无人自主系统跨域协同作战试验系统工程

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Numerical study of liquid coverage in a gas-liquid-solid packed bed

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Particuology 2015年第6期13卷 90-99页

作者： wei du Lifeng Zhang Sha Lv Panpan Lu Jian xu weisheng wei State Key Laboratory of Heavy Oil Processing China University of Petroleum Beijing 102249 China The Key Laboratory of Catalysis China National Petroleum Corp. China University of Petroleum Beijing 102249 China Department of Chemical and Biological Engineering University of Saskatchewan Saskatoon SK Canada

In this work, computational fluid dynamics （CFD） simulations using the volume-of-fluid （VOF） model were employed to investigate the effects of liquid properties, liquid and gas flow rates, and wettability of particles on liquid maldistribution at the microscopic level in a fixed bed reactor. The simulation results show that the number of wetted particles decreases with increasing gas velocity, consequently leading to lower liquid-solid contact areas. The radial liquid distribution is greatly enhanced by increasing the liquid flow rate, whereas the time for the liquid to pass through the whole bed is decreased, as expected. Based on simulation results, it was found that the liquid-solid contact area can be increased by using liquids of high viscosities and more wettable particles. However, the flow-through time increases with increasing liquid viscosity. An increase in the gas density showed a minimal impact on the liquid flow- through time, and the liquid density does not impact the radial liquid distribution or the liquid flow time within a range of liquid densities typically encountered in the petrochemical industry.

关键词： CFD VOF Liquid-solid contact area Radial liquid distribution Fixed bed

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四级低反力度压气机初步设计及流动分析

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工程热物理学报 2024年第6期45卷 1696-1702页

作者：罗樵罗磊杜巍王松涛周逊哈尔滨工业大学能源科学与工程学院哈尔滨150001

本文将两种单级低反力度压气机的设计思想应用于多级低反力度压气机设计,初步设计了一台四级低反力度高负荷压气机。在一维设计中初步确定四级低反力度压气机的各级参数,使用三维数值模拟计算对一维设计结果进行评估,同时对四级低反力... 详细信息

本文将两种单级低反力度压气机的设计思想应用于多级低反力度压气机设计,初步设计了一台四级低反力度高负荷压气机。在一维设计中初步确定四级低反力度压气机的各级参数,使用三维数值模拟计算对一维设计结果进行评估,同时对四级低反力度压气机三维数值模拟结果的整体性能和内部流动进行初步分析。结果显示,四级总压比能达到6以上,设计点附近效率不低于88%,末级静子中的流动分离也在可控制的范围内。

关键词：低反力度压气机附面层抽吸三维数值模拟

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