检索结果-南通市图书馆

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang Li Li‑jiao Wang Xiang‑Biao Qiu Jing‑Wen Li wei Xu Tao Li Ze‑Bin Lin Chang‑Jun Ning Yong‑Hao Chen Rui‑Rui Fan Kang Sun Jing‑Yu Tang Rong Zhang Han‑Tao Jing Bo Mei Qi An Hao‑Fan Bai jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping Chen Zhen Chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑wei Hu Han‑Xiong huang wei‑hua jia Hao‑Yu jiang wei jiang Zhi‑Jie jiang Zheng‑Yao Jin Ling Kang Bo Li Chao Li Gong Li jia‑Wen Li Xiao Li Yang Li Jie Liu Rong Liu Shu‑Bin Liu Guang‑Yuan Luan Bin‑Bin Qi Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan Sheng‑Da Tang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑wei Wen Xiao‑Guang Wu Xuan Wu Li‑Kun Xie Yi‑wei Yang Han Yi Yong‑Ji Yu Guo‑Hui Zhang Lin‑Hao Zhang Mo‑Han Zhang Qi‑wei Zhang Xian‑Peng Zhang Yu‑Liang Zhang Yue Zhang Zhi‑Yong Zhang Mao‑Yuan Zhao Lu‑Ping Zhou Zhi‑Hao Zhou Ke‑Jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang Yong-Hao Chen Jing-Yu Tang Rui-Rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-wei Yang Rong Liu Han Yi Yang Li Zhen Yang Qi An Hao-Fan Bai jiang-Bo Bai Jie Bao Ping Cao Qi-Ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-wei Hu Han-Xiong huang wei-hua jia Hao-yu jiang wei jiang Zhi-jie jiang Ling Kang Bo Li Chao Li jia-Wen Li Xiao Li Jie Liu Shu-Bin Liu Guang-Yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin Tan Li-jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Mo-Han Zhang Qi-wei Zhang Xian-Peng Zhang Yu-Liang Zhang Yue Zhang Zhi-Yong Zhang Mao-Yuan Zhao Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

A comprehensive genomic characterization of esophageal squamous cell carcinoma: from prognostic analysis to in vivo assay

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2016年第9期35卷 435-437页

作者： Yuan-Bin Chen wei-hua jia Sun Yat?sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine

Background: Esophageal squamous cell carcinoma(ESCC) is a leading cause of cancer death worldwide and is char?acterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Addition?ally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus, there is an urgent need to find efficient therapy targets. Previous ESCC high?throughput genomic studies have lacked intensive survival analysis, particularly for copy number variation(CNV) and the genes *** body: In the study "Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis" recently published in the American Journal of Human Genetics, we comprehensively analyzed the effects of CNVs, mutations, and relative gene expression on patient outcomes. To validate our findings for our 67 sequencing samples, we collected a 321?patient retrospective cohort with detailed 5?year follow?up information and carried out univariate and multivariate survival analyses. In addition, the biological functions of the survival predictors in ESCC were investigated both in vitro and in ***: We found the independent ESCC survival predictors and potential therapy targets. Nevertheless, the effects of numerous low?frequency mutations need to be explored using larger sample sequencing. Overall, con?structing multi?gene prognostic signatures will remain a great challenge in the future.

关键词：鳞状细胞癌基因组特征基因组学体内分析食管癌预后基因突变预测因子

Cumulative scores based on plasma D-dimer and serum albumin levels predict survival in esophageal squamous cell carcinoma patients treated with transthoracic esophagectomy

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2016年第3期35卷 133-141页

作者： De-Qing Liu Fang-Fang Li wei-hua jia State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer Center Department of Radiation Oncology Chongqing Cancer Institute

Background:Recently,studies have shown that plasma D-dimer and serum albumin are prognostic markers for esophageal *** purpose of this study was to evaluate a novel prognostic scoring system—DA score(combination of preoperative plasma D-dimer and serum albumin levels)—and analyze the association between survival of patients with esophageal squamous cell carcinoma(ESCC) and their Glasgow prognostic ***:In this retrospective study,preoperative biochemical markers and clinicopathologic factors in 260 ESCC patients treated with transthoracic esophagectomy were *** to receiver operating characteristic analysis,the cutoff values of D-dimer and albumin were defined as 0.5 μg/mL and 43.8 g/L,*** with high D-dimer levels(>0.5 μg/mL) and low albumin levels(<43.8 g/L) were assigned a score of 2,those with only one of the two abnormalities were assigned a score of 1,and those with neither of the two abnormalities were assigned a score of ***:ESCC patients with a DA score of 0,l,and 2 numbered 55,116,and 89,*** analysis showed that patients with a DA score of 2 had lower overall survival(OS) rates than those with DA scores of 1 and 0(37.1%vs.52.6%and 76.4%,P < 0.001);similar findings were observed for disease-free survival(DFS) rates(32.6%vs.44.8%and67.3%,P < 0.001).In addition,the predictive value of the DA score was also significant in patients with stages l-IIA and stages IIB-IV *** Cox regression analyses indicated that hazard ratios(HRs) for predicting OS of patients with DA scores 1 and 2 were 2.25 {P — 0.010) and 3.14(P< 0.001),respectively,compared with those with a DA score of 0,and HRs for predicting DFS of patients with DA scores of 1 and 2 were 1.86(P = 0.023) and 2.68(P < 0.001),respectively,compared with those with a DA scores of ***:Our study suggests that preoperative DA scores are notably associated with postoperative survival of ESCC patients.

关键词： DA score, Esophageal squamous cell carcinoma, Survival, Prognostic factors, Transthoracicesophagectomy

Centrifugation: an important pre-analytic procedure that influences plasma microRNA quantification during blood processing

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2013年第12期32卷 667-672页

作者： Xiao-Hui Zheng Cui Cui Xin-Xi Zhou Yi-Xin Zeng wei-hua jia State Key Laboratory of Oncology in South China Bank of Tumor Resource Sun Yat-sen University Cancer Center

Circulating microRNAs are robustly present in plasma or serum and have become a research focus as biomarkers for tumor diagnosis and *** is a necessary procedure for obtaining highquality blood ***,we investigated one-step and two-step centrifugations,two centrifugal methods routinely used in microRNA study,to explore their effects on plasma microRNA *** microRNAs obtained from one-step and two-step centrifugations were quantified by microarray and TaqMan-based real-time quantitative polymerase chain reaction(Q-PCR).Dynamic light scattering was performed to explore the difference underlying the two centrifugal *** results from the microarray containing 1,347 microRNAs showed that the signal detection rate was greatly decreased in the plasma sample prepared by two-step *** importantly,the microRNAs missing in this plasma sample could be recovered and detected in the precipitate generated from the second *** with the results from microarray,a marked decrease of three representative microRNAs in twostep centrifugal plasma was validated by *** to the size distribution of all nanoparticles in plasma,there were fewer nanoparticles with size>1,000 nm in two-step centrifugal *** experiments directly demonstrated that different centrifugation methods produced distinct quantities of plasma ***,exosomes or protein complexes containing microRNAs may be involved in large nanoparticle formation and may be precipitated after two-step *** results remind us that sample processing methods should be first considered in conducting research.

关键词： microRNA 离心分离血浆定量分析血液预分析小分子RNA 微小RNA

GWAS signals across the HLA regions:revealing a clue for common etiology underlying infectious tumors and other immunity diseases

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2011年第4期30卷 226-230页

作者： Yin Yao Shugar Ying Wang wei-hua jia Yi-Xin Zeng Unit of Statistical Genomics Intramural Research Program National Institute of Mental Health National Institute of Health Bethesda Maryland 20892 USA Department of Psychiatry and Behavioral Sciences the Johns Hopkins University School of Medicine Baltimore Maryland 21287 USA State Key Laboratory ot Oncology in South China Guangzhou Guangdong 510060 P. R. China Department of Experimental Research Sun Yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China.

Increasing evidence suggests that multiple genes in the human leukocyte antigen(HLA) regions play an important role in development of cancers and immunity ***,the biological mechanisms of the HLA associations are not well *** recently conducted a survey of all genome-wide association studies(GWAS) with significant findings in the HLA regions and concluded that diseases such as cancer and immune disorders are more likely to be associated with genetic variants located in the HLA regions than other *** finding is suggestive for testing a hypothesis of a common etiology of infectious tumors and other immunity diseases.

关键词：免疫系统 HLA 传染性疾病病因肿瘤人类白细胞抗原信号

Robust reliable control for a class of time-varying uncertain impulsive systems

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University of Technology 2005年第Z1期12卷 199-202页

作者： CHENG Xin-ming GUI wei-hua GAN Zheng-jia School of Information Science and Engineering Central South University Changsha 410083 China School of Information Science and Engineering Central South University Changsha 410083 China School of Computer and Communication Changsha University of Science and Technology Changsha 410076 China

The problem of robust and reliable control design for linear uncertain impulsive systems with both timevarying norm-bounded parameter uncertainty and actuator failures was studied. The actuators are classified into two groups. One set of actuators susceptible to failures is possible to fail, the other set of actuators robust to failures is assumed never to fail. The outputs of the actuator failures are regarded as zero. The purpose is to design the state feedback controller such that, for all admissible uncertainties as well as actuator failures occurring among a prespecified subset of actuators, the plant remains asymptotically stable. A modified algebraic Riccati equation approach was developed to solve the problem addressed and a robust reliable control law was obtained. An numerical example was also offered to prove the effectiveness of the proposed method.

关键词： reliable control uncertain impulsive systems state feedback stabilization

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

寒冷地区热湿耦合下墙体热桥的模拟研究

节能 2024年第6期43卷 10-13页

作者：李会敏王海涛魏家骅李建河南工业大学土木工程学院河南郑州450001

在寒冷地区气候条件下,通过COMSOL Multiphysics模拟软件建立热湿耦合模型,对钢筋混凝土柱红砖砌体墙所形成柱墙角热桥进行模拟研究。结果表明,湿传递的作用比只有传热作用的墙体内表面温度低,在实际工况下不能忽略湿传递对建筑材料导... 详细信息

在寒冷地区气候条件下,通过COMSOL Multiphysics模拟软件建立热湿耦合模型,对钢筋混凝土柱红砖砌体墙所形成柱墙角热桥进行模拟研究。结果表明,湿传递的作用比只有传热作用的墙体内表面温度低,在实际工况下不能忽略湿传递对建筑材料导热系数的影响。由于热桥的影响使围护结构的热通量增加19.6%,热桥的影响区域为距离最不利点0.4 m左右,在相同保温板厚度时,外保温比内保温墙体内表面温度高,保温效果更好。随着保温板厚度的增加,墙体内表温度升高,墙体内表面热通量降低。为了降低冬季房间供暖能耗,可以通过对热桥外保温来解决墙体结露现象。

关键词：热湿耦合传递热桥效应露点温度热湿模拟

Potential factors associated with clinical stage of nasopharyngeal carcinoma at diagnosis: a case–control study

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2017年第10期36卷 478-487页

作者： Jun-Ting Ren Meng-Yu Li Xiao-Wen Wang Wen-Qiong Xue Ze-Fang Ren wei-hua jia School of Public Health Sun Yat-sen University 74 Zhongshan 2nd RdGuangzhou 510080 Guangdong P. R. China State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Sun Yat-sen University Cancer Center 651 Dongfeng East Rd Guangzhou 510060 GuangdongP. R. China

Background: In China, most patients with nasopharyngeal carcinoma(NPC) are diagnosed at a late stage and con?sequently have a poor prognosis. This study aimed to investigate potential factors associated with the clinical stage of NPC at ***: Data were obtained from 118 patients with early?stage NPC and 274 with late?stage NPC who were treated at Sun Yat?sen University Cancer Center between August 2014 and July 2015. Patients were individually matched by age, sex, and residence, and a conditional logistic regression model was applied to assess the associa?tions of clinical stage at diagnosis with socioeconomic status indicators, knowledge of NPC, physical examinations, patient interval, and risk factors for ***: Although knowledge of early NPC symptoms, smoking cessation, and patient interval were important fac?tors, the number of cigarettes smoked per day, motorbike ownership, and physical examination exhibited the strong?est associations with the clinical stage of NPC at diagnosis. Compared with smoking fewer than ten cigarettes a day, smoking 10–30 cigarettes [odds ratio(OR) 4.03; 95% confidence interval(CI) 1.11–14.68] or more than 30 cigarettes(OR 11.46; 95% CI 1.26–103.91) was associated with an increased risk of late diagnosis. Compared with not owning a motorbike, owning a motorbike(OR 0.38; 95% CI 0.23–0.64) was associated with early diagnosis. Subjects who under?went physical examinations were less likely to receive a late diagnosis than those who did not undergo examinations(OR 0.50; 95% CI 0.28–0.89). However, indicators of wealth were not significant ***: Initiatives to improve NPC patient prognosis should aim to promote knowledge about early symptoms and detection, health awareness, and accessibility to health facilities among all patients, regardless of socioeconomic status.

关键词： Nasopharyngeal carcinoma Stage Socioeconomic status Cancer cognition China