With the development of quantum computing technology,quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key *** paper designs a quantum trapdoor one-way function via ...
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With the development of quantum computing technology,quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key *** paper designs a quantum trapdoor one-way function via EPR pairs and quantum *** on this,a new quantum public-key cryptosystem is presented,which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext *** with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition,which is also detailed in the paper.
Multimodal sensor fusion can make full use of the advantages of various sensors,make up for the shortcomings of a single sensor,achieve information verification or information security through information redundancy,a...
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Multimodal sensor fusion can make full use of the advantages of various sensors,make up for the shortcomings of a single sensor,achieve information verification or information security through information redundancy,and improve the reliability and safety of the *** intelligence(AI),referring to the simulation of human intelligence in machines that are programmed to think and learn like humans,represents a pivotal frontier in modern scientific *** the continuous development and promotion of AI technology in Sensor 4.0 age,multimodal sensor fusion is becoming more and more intelligent and automated,and is expected to go further in the *** this context,this review article takes a comprehensive look at the recent progress on AI-enhanced multimodal sensors and their integrated devices and *** on the concept and principle of sensor technologies and AI algorithms,the theoretical underpinnings,technological breakthroughs,and pragmatic applications of AI-enhanced multimodal sensors in various fields such as robotics,healthcare,and environmental monitoring are *** a comparative study of the dual/tri-modal sensors with and without using AI technologies(especially machine learning and deep learning),AI-enhanced multimodal sensors highlight the potential of AI to improve sensor performance,data processing,and decision-making ***,the review analyzes the challenges and opportunities afforded by AI-enhanced multimodal sensors,and offers a prospective outlook on the forthcoming advancements.
Severe ground-level ozone(O_(3))pollution over major Chinese cities has become one of the most challenging problems,which have deleterious effects on human health and the sustainability of *** study explored the spati...
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Severe ground-level ozone(O_(3))pollution over major Chinese cities has become one of the most challenging problems,which have deleterious effects on human health and the sustainability of *** study explored the spatiotemporal distribution characteristics of ground-level O_(3) and its precursors based on conventional pollutant and meteorological monitoring data in Zhejiang Province from 2016 to ***,a high-performance convolutional neural network(CNN)model was established by expanding the moment and the concentration variations to general ***,the response mechanism of O_(3) to the variation with crucial influencing factors is explored by controlling variables and interpolating target *** results indicated that the annual average MDA8-90th concentrations in Zhejiang Province are higher in the northern and lower in the *** the wind direction(WD)ranges from east to southwest and the wind speed(WS)ranges between 2 and 3 m/sec,higher O_(3) concentration prone to *** different temperatures(T),the O_(3) concentration showed a trend of first increasing and subsequently decreasing with increasing NO_(2) concentration,peaks at the NO_(2) concentration around 0.02mg/m^(3).The sensitivity of NO_(2) to O_(3) formation is not easily affected by temperature,barometric pressure and dew point ***,there is a minimum IRNO_(2) at each temperature when the NO_(2) concentration is 0.03 mg/m^(3),and this minimum IRNO_(2) decreases with increasing *** study explores the response mechanism of O_(3) with the change of driving variables,which can provide a scientific foundation and methodological support for the targeted management of O_(3) pollution.
BACKGROUND Colorectal cancer(CRC)is one of the most common malignant gastrointestinal tumors worldwide,with high incidence and mortality *** To investigate the expression significance of the chromatin-remodeling prote...
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BACKGROUND Colorectal cancer(CRC)is one of the most common malignant gastrointestinal tumors worldwide,with high incidence and mortality *** To investigate the expression significance of the chromatin-remodeling protein MORC family CW-type zinc finger 4(MORC4)as a biomarker in CRC patients,and to explore its relationship with pathological features and *** A total of 143 CRC specimens and 57 adjacent tissue specimens,surgically removed from our hospital between January 2020 and January 2021,were ***4 protein expression was assessed using immunohistochemistry after paraffin *** relationship between MORC4 protein expression and clinicopathological characteristics of patients was ***-Meier survival curves were plotted to analyze the relationship between MORC4 protein expression and prognosis in CRC *** Compared with adjacent tissues,the expression rate of MORC4 protein in CRC tissues was significantly higher(P0.05).However,significant differences were found in the high expression rate of MORC4 protein in patients with different degrees of differentiation,lymph node metastasis,distant metastasis,tumor-lymph node-metastasis stage,and serum carcinoembryonic antigen levels(P<0.05).Compared with patients with low MORC4 expression,patients with high MORC4 expression had a worse prognosis(P<0.05).CONCLUSION The upregulation of MORC4 expression in CRC patients is closely related to disease severity and prognosis,suggesting its potential as an evaluation biomarker,which warrants further investigation.
In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were invest...
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In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were investigated by using a single factor variable *** surface morphologies of the shell molds produced by different temperatures of the surface(first)layer slurries were observed via electron ***,the microscopic composition of these shell molds was obtained by EDS,and the osmotic effect of the slurry on the wax patterns at different temperatures was also assessed by the PZ-200 Contact Angle *** forming reasons for the surface cracks and holes of thick and large ZTC4 titanium alloy by investment casting were *** experimental results show that the surface of the shell molds prepared by the surface layer slurry with a low temperature exhibits noticeable damage,which is mainly due to the poor coating performance and the serious expansion and contraction of wax pattern at low *** second layer shell material(SiO_(2),Al_(2)O_(3))immerses into the crack area of the surface layer,contacts and reacts with the molten titanium to form surface cracks and holes in the *** the increase of the temperature of surface layer slurry,the damage to the shell surface tends to weaken,and the composition of the shell molds'surface becomes more uniform with less *** results show that the surface layer slurry at 22℃is evenly coated on the surface of the wax patterns with appropriate thickness,and there is no surface shell mold rupture caused by sliding slurry after sand *** surface layer slurry temperature is consistent with the wax pattern temperature and the workshop temperature,so there is no damage of the surface layer shell caused by expansion and ***,the shell mold prepared by the surface layer slurry at this temperature has good integrity,isolating the contact between the low inert
The physical layer key generation technique provides an efficient method,which utilizes the natural dynamics of wireless ***,there are some extremely challenging security scenarios such as static or quasi-static envir...
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The physical layer key generation technique provides an efficient method,which utilizes the natural dynamics of wireless ***,there are some extremely challenging security scenarios such as static or quasi-static environment,which lead to the low randomness of generated ***,the coefficients of the static channel may be dropped into the guard space and discarded by the quantization approach,which causes low key generation *** tackle these issues,we propose a random coefficient-moving product based wireless key generation scheme(RCMP-WKG),where new random resources with remarkable fluctuations can be obtained by applying random coefficient and by moving product on the legitimate ***,appropriate quantization approaches are used to increase the key generation ***,the security of our proposed scheme is evaluated by analyzing different attacks and the eavesdropper’s mean square error(MSE).The simulation results reveal that the proposed scheme can achieve better performances in key capacity,key inconsistency rate(KIR)and key generation rate(KGR)compared with the prior works in static ***,the proposed scheme can deteriorate the MSE performance of the eavesdropper and improve the key generation performance of legitimate nodes by controlling the length of the moving product.
Garnet li_(7)La_(3)Zr_(2)O_(12)(LLZO)electrolytes have been recognized as a promising candidate to replace liquid/molten-state electrolytes in battery applications due to their exceptional performance,particularly Ga-...
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Garnet li_(7)La_(3)Zr_(2)O_(12)(LLZO)electrolytes have been recognized as a promising candidate to replace liquid/molten-state electrolytes in battery applications due to their exceptional performance,particularly Ga-doped LLZO(LLZGO),which exhibits high ionic ***,the limited size of the liþtransport bottleneck restricts its high-current discharging *** present study focuses on the synthesis of Ga^(3+)þand Ba^(2+)þco-doped LLZO(LLZGBO)and investigates the influence of doping contents on the morphology,crystal structure,liþtransport bottleneck size,and ionic *** particular,Ga_(0.32)Ba_(0.15)exhibits the highest ionic conductivity(6.11E-2 S cm^(-1) at 550 C)in comparison with other compositions,which can be attributed to its higher-energy morphology,larger bottleneck and unique liþtransport *** addition to Ba^(2+),Sr^(2+)þand Ca^(2+)have been co-doped with Ga3þinto LLZO,respectively,to study the effect of doping ion radius on crystal structures and the properties of *** characterization results demonstrate that the easier liþtransport and higher ionic conductivity can be obtained when the electrolyte is doped with larger-radius *** a result,the assembled thermal battery with Ga_(0.32)Ba_(0.15)-LLZO electrolyte exhibits a remarkable voltage platform of 1.81 V and a high specific capacity of 455.65 mA h g^(-1) at an elevated temperature of 525℃.The discharge specific capacity of the thermal cell at 500 mA amounts to 63%of that at 100 mA,showcasing exceptional high-current discharging *** assembled as prototypes with fourteen single cells connected in series,the thermal batteries deliver an activation time of 38 ms and a discharge time of 32 s with the current density of 100 mA cm^(-2).These findings suggest that Ga,Ba co-doped LLZO solid-state electrolytes with high ionic conductivities holds great potential for high-capacity,quick-initiating and high-current discharging thermal batteries.
Electronic circular dichroism(ECD)spectrum is an important tool for as-sessing molecular ***-al methods,like linear response time-dependent density functional theory(LR-TDDFT),predict ECD spectra well for small or med...
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Electronic circular dichroism(ECD)spectrum is an important tool for as-sessing molecular ***-al methods,like linear response time-dependent density functional theory(LR-TDDFT),predict ECD spectra well for small or medium-sized molecules,but struggle with large sys-tems due to high computational costs,making it a significant challenge to ac-curately and efficiently predict the ECD properties of complex *** the framework of the generalized energy-based fragmentation(GEBF)method for localized excited states(ESs)calculation,we propose a combination algorithm for calculating rotatory strengths of ESs in condensed phase *** algorithm estimates the rotatory strength of the total system by calculating and combin-ing the transition electric and magnetic dipole moments of *** have used the GEBF method to calculate the ECD properties of chiral drug molecule derivatives,green fluo-rescent protein,and cyclodextrin derivatives,and compared their results with traditional methods or experimental *** results show that this method can efficiently and accu-rately predict the ECD spectra of these ***,the GEBF method for ECD spectra demonstrates great potential in the chiral analysis of complex systems and chiral material design,promising to become a powerful theoretical tool in chiral chemistry.
The proteasome, an evolutionarily conserved proteolytic complex comprising the 20S core particle and 19S regulatory particles, performs both shared and distinct ***, a highly complex developmental process, relies on p...
The proteasome, an evolutionarily conserved proteolytic complex comprising the 20S core particle and 19S regulatory particles, performs both shared and distinct ***, a highly complex developmental process, relies on proteasome activity at multiple stages to regulate protein turnover. In this study, we selected the20S subunit PSMA1 and 19S regulatory subunit PSMD2 to investigate the potential functions of the proteasome in spermatogenesis. Using Psma1-EGFP and Psmd2-mCherry knock-in mouse models, we confirmed the expression of both subunits in all spermatogenic cell types,with pronounced presence in early germ cell *** further clarify their functional significance, we specifically knocked out Psma1 and Psmd2 in germ *** of either PSMA1 or PSMD2 led to disrupted spermatogenesis, characterized by the complete absence of sperm in the epididymis. Subsequent analysis indicated that loss of these proteasome components impaired meiotic initiation. Psma1 and Psmd2 knockout germ cells showed accumulation of DMRT1, a key regulator of mitosis-to-meiosis transition, leading to a reduction in STRA8 levels and consequent disruption of meiosis initiation. This study sheds light on the molecular mechanisms that govern meiotic initiation and identifies potential genes associated with male infertility.
BACKGROUND The prevalence of diabetes and its association with microcirculatory dysfunction presents a significant challenge in contemporary global *** this nexus is crucial for developing targeted therapeutic *** To ...
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BACKGROUND The prevalence of diabetes and its association with microcirculatory dysfunction presents a significant challenge in contemporary global *** this nexus is crucial for developing targeted therapeutic *** To trace the progression and delineate the current state of interdisciplinary research concerning diabetes and *** Employing a bibliometric approach,this study scrutinizes 12886 peer-reviewed publications retrieved from the PubMed and Web of Science *** focus is on elucidating the research trajectory and thematic concentrations at the confluence of diabetes and *** Research outputs have surged since 2011,with the United States,China,and the United Kingdom leading in the quantity and quality of *** analysis revealed that journals such as Diabetes Care and The New England Journal of Medicine,along with top research institutions,have significantly contributed to advancing the understanding of microvascular processes affected by *** central themes identified include inflammation,oxidative stress,and endothelial dysfunction,which are critical in mediating the microvascular complications of *** This bibliometric evaluation reveals an evolving landscape focusing on diabetes and microcirculatory *** complexity of diabetic microvascular issues encouraged multidisciplinary research strategies that are imperative for global health outcomes.
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