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Fungal assembly of L-asparaginase using solid-state fermentation:a review

BIOCELL 2020年第2期44卷 147-155页

作者： SALLY NASER wesameldin saber MOHAMMAD EL-METWALLY MAHMOUD MOUSTAFA ATTALLA EL-KOTT Life Sciences Department College of Science and Literature Mahyel AseerKing Khalid UniversityAbhaSaudi Arabia Unit of Food Bacteriology Central Laboratory of Food HygieneMinistry of HealthBranch in ZagazigSharkiaEgypt Microbial Activity Unit Department of MicrobiologySoilsWater and Environment Research InstituteAgricultural Research CenterGizaEgypt Botany and Microbiology Department Faculty of ScienceDamanhour UniversityEl-BeheraEgypt Biology Department College of ScienceKing Khalid UniversityAbha9004Saudi Arabia Botany and Microbiology Department Faculty of ScienceSouth Valley UniversityQenaEgypt Zoology Department Faculty of ScienceDamanhour UniversityEl-BeheraEgypt

Because of its antitumor therapeutic-activity,as well as its application in food industries to improve the quality,L-asparaginase has attracted considerable attention from several *** recent years,fungi have occupied advanced rank among microorganisms in the production process of the *** review is spotting the light on the advantages of fungal enzyme and its applications in the food industry and *** solid-state fermentation was discussed as the wide alternative and most accepted biosynthesis ***,some lights were also spotted to the statistical experimental design of the fermentation process,mainly on the methodology of the response surface for L-asparaginase biosynthesis by ***,the immobilization of the enzyme and the features of the widely used solid substrates for the maximization of the production process were explored.

关键词： Immobilization Statistical designs Response surface methodology Optimization

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Secondary antiviral metabolites from fungi with special reference to coronaviruses

引用

BIOCELL 2022年第8期46卷 1979-1988页

作者： MOHAMED SALEM MOHAMMAD EL-METWALLY wesameldin saber SALLY NEGM ATTALLA EL-KOTT YASSER MAZROUA ABEER MAKHLOUF MAHMOUD MOUSTAFA Department of Chemistry Faculty of Science and ArtKing Khalid UniversityMohailAssirSaudi Arabia Department of Chemistry Faculty of ScienceAl-Azhar UniversityCairoEgypt Botany and Microbiology Department Faculty of ScienceDamanhour UniversityEl-BeheraEgypt Microbial Activity Unit Department of MicrobiologySoilsWater and Environment Research InstituteAgricultural Research CenterGizaEgypt Life Sciences Department College of Science and ArtKing Khalid UniversityMohailAseerSaudi Arabia Unit of Food Bacteriology Central Laboratory of Food HygieneMinistry of HealthSharkiaEgypt Department of Biology College of ScienceKing Khalid UniversityAbhaSaudi Arabia Zoology Department Faculty of ScienceDamanhour UniversityEl-BeheraEgypt Department of Business Administration Community CollegeKing Khalid UniversityAbhaSaudi Arabia Department of Agricultural Economics Faculty of AgricultureTanta UniversityTantaEgypt Department of Botany Faculty of AgricultureMenoufia UniversitySheben El-KomMenoufiaEgypt Botany and Microbiology Department Faculty of ScienceSouth Valley UniversityQenaEgypt

Profound inspection of the life forms on the earth teaches how to be the complexity of interrelationships among the various *** of the emergence of novel viruses all the time and the inadequate of vaccines and antivirals,viral contagions are amongst the most causative diseases affecting people *** exemplify a massive source of bioactive molecules as,many fungal secondary metabolities like Oxoglyantrypine,Carneic acid F,Scedapin C,Asteltoxin E,Phomanolide,Norquinadoline A and Quinadoline B have antiviral *** review deals with how secondary metabolites of fungi can help in the war against viruses in general and especially Coronaviruses moreover several pieces of literature pointed out that many clusters of fungi in different biotopes are waiting to be exploited.

关键词： COVID-19 SARS-CoV-2 Antibiotics Virus Fungi

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