检索结果-南通市图书馆

Remodeling tumor Immune microenvironment by Using Polymer-Lipid-manganese Dioxide Nanoparticles with Radiation therapy to Boost Immune Response of Castration-Resistant Prostate Cancer

引用

Research 2024年第3期2023卷 83-96页

作者： Abdulm.t.aleb E.Zetrini HoYin Lip Azhar Z.Abbasi Ibrahim Alradwan taksim Ahmed Chunsheng He Jeffrey t.Henderson Andrew m.Rauth Xiao Yu Wu Advanced Pharmaceutics and Drug Delivery Laboratory Leslie Dan Faculty of PharmacyUniversity of TorontoM5S 3M2TorontoONCanada. Departments of medical Biophysics and Radiation Oncology University of TorontoM5G 1L7TorontoONCanada.

Despite substantial progress in the treatment of castration-resistant prostate cancer (CRPC), including radiation therapy and immunotherapy alone or in combination, the response to treatment remains poor due to the hypoxic and immunosuppressive nature of the tumor microenvironment. Herein, we exploited the bioreactivity of novel polymer–lipid manganese dioxide nanoparticles (PLmDs) to remodel the tumor immune microenvironment (tImE) by increasing the local oxygen levels and extracellular pH and enhancing radiation-induced immunogenic cell death. this study demonstrated that PLmD treatment sensitized hypoxic human and murine CRPC cells to radiation, significantly increasing radiation-induced DNA double-strand breaks and ultim.t.ly cell death, which enhanced the secretion of damage-associated molecular patterns, attributable to the induction of autophagy and endoplasmic reticulum stress. Reoxygenation via PLmDs also polarized hypoxic murine RAW264.7 macrophages toward the m1 phenotype, enhancing tumor necrosis factor alpha release, and thus reducing the viability of murine CRPC tRAmP-C2 cells. In a syngeneic tRAmP-C2 tumor model, intravenous injection of PLmDs suppressed, while radiation alone enhanced recruitment of regulatory t cells and myeloid-derived suppressor cells. Pretreatment with PLmDs followed by radiation down-regulated programmed death-ligand 1 and prom.t.d the infiltration of antitumor CD8+ t cells and m1 macrophages to tumor sites. taken together, tImE modulation by PLmDs plus radiation profoundly delayed tumor growth and prolonged median survival compared with radiation alone. these results suggest that PLmDs plus radiation is a promising treatment modality for improving therapeutic efficacy in radioresistant and immunosuppressive solid tumors.

关键词： RAW264.7 alone treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In situ tEm investigation of electron irradiation and aging-induced high-density nanoprecipitates in an mg-10Gd-3Y-1Zn-0.5Zr alloy

引用

Journal of magnesium and Alloys 2024年第5期12卷 1841-1853页

作者： m.Lv H.L.Ge Q.Q.Jin X.H.Shao Y.t.Zhou B.Zhang X.L.ma Shenyang National Laboratory for m.t.rials Science Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China School of m.t.rials Science and Engineering University of Science and Technology of ChinaShenyang 110016China m.t.rials Science and Engineering Research Center Guangxi University of Science and TechnologyLiuzhou 545006China

In-situ electron irradiation and aging are applied to introduce high-density precipitates in an mg-10Gd-3Y-1Zn-0.5Zr(GWZ1031K,wt.%)alloy to improve the *** results show that the hardness of the mg alloy after irradiation for 10 h and aging for 9 h at 250℃ is 1.64 GPa,which is approxim.t.ly 64% higher than that of the samples before being *** is mainly attributed to γ'precipitates on the basal plane after irradiation and the high-density nanoscale β'precipitates on the prism.t.c plane after aging,which should be closely related to the irradiation-induced homogenous *** latter plays a key role in precipitation *** result paves a way to improve the mechanical properties of m.t.llic m.t.rials by tailoring the precipitation through irradiation and aging.

关键词： mg alloy Electron beam irradiation Hardening Precipitates In-situ tEm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features:Case studies on two Brazilian urban centers

引用

Infectious Disease modelling 2024年第1期9卷 142-157页

作者： Ana t.C.Silva Rejane C.Dorn Lívia R.tomás Leonardo B.L.Santos Lacita m.Skalinski Suani t.R.Pinho Departamento de Física Universidade Estadual de Feira de SantanaAv.Transnordestinas/n.Novo HorizonteFeira de Santana44036-900BABrazil Instituto de Física Universidade Federal da BahiaRua Barão de Jeremoabo s/nCampus Universitário de OndinaSalvador40170-115BABrazil Centro Nacional de monitoramento e Alertas de Desastres Naturais(CEmADEN) Estrada Dr.Altino Bondensan500São Josédos Campos12247-016SPBrazil Universidade Estadual de Santa Cruz Campus Soane Nazaréde AndradeRodovia Jorge AmadoKm 16SalobrinhoIlhéus45662-900BABrazil Instituto de Saúde Coletiva Universidade Federal da BahiaR.Basílio da Gamas/n-CanelaSalvador40110-140BABrazil Instituto Nacional de Ciência e tecnologia-Sistemas Complexos Virtual InstitutionBrazil

the study of the propagation of infectious diseases in urban centers finds a close connection with their population's social characteristics and *** work performs a spatial analysis of dengue cases in urban centers based on the basic reproduction numbers,R0,and incidence by planning areas(PAs),as well as their correlations with the Human Development Index(HDI)and the number of *** analyzed dengue epidemics in 2002 at two Brazilian urban centers,Belo Horizonte(BH)and Rio de Janeiro(RJ),using PAs as spatial *** results reveal heterogeneous spatial scenarios for both cities,with very weak correlations between R0 and both the number of trips and the HDI;in BH,the values of R0 show a less spatial heterogeneous pattern than in *** BH,there are moderate correlations between incidence and both the number of trips and the HDI;meanwhile,they weakly correlate for ***,the absence of strong correlations between the considered measures indicates that the transmission process should be treated considering the city as a whole.

关键词： Dengue m.t.em.t.cal mode lBasic reproduction number Urban mobility Urban indices

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of Lorentz forces on forced-convection nanofluid flow over a stretched surface

引用

Particuology 2016年第3期14卷 108-113页

作者： mohsen Sheikholeslami m.t. mustafa Davood Domiri Ganji Department of mechanical Engineering Babol University of Technology Babol Islamic Republic oflran Department of m.t.em.t.cs Statistics and Physics Qatar University Doha 2713 Qatar

magnetic nanofiuid hydrothermal analysis over a plate is studied that includes consideration of thermal radiation. the Runge-Kutta （RK4） m.t.od is utilized to get solution of ODEs which are obtained from similarity solution. In considering the impacts of Brownian m.t.on, we applied Koo-Kleinstreuer-Li cor- relation to simulate the properties of CuO-water. the influence is discussed of important param.t.rs such as the temperature index, magnetic, radiation, and velocity ratio param.t.rs and volume fraction of nanoparticle on hydrothermal behavior. Results illustrate that the coefficient of skin friction enhances with enhancing magnetic param.t.r while reduces with enhancing velocity ratio param.t.r. Also the Nusselt number was found to directly depend on the velocity ratio and temperature index param.t.rs but has an inverse dependence on the magnetic and radiation param.t.rs.

关键词： Nanofluid Brownian m.t.on thermal radiation magnetohydrodynamic Stretching sheet

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Low crude protein formulation with supplemental amino acids for its impacts on intestinal health and growth performance of growing-finishing pigs

引用

Journal of Animal Science and Biotechnology 2024年第4期15卷 1590-1606页

作者： marcos Elias Duarte Wanpuech Parnsen Shihai Zhang marvio L.t.Abreu Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

Background Low crude protein(CP)formulations with supplemental amino acids(AA)are used to enhance intestinal health,reduce costs,minimize environmental impact,and maintain growth performance of ***,extensive reduction of dietary CP can compromise growth performance due to lim.t.d synthesis of non-essential AA and lim.t.d availability of bioactive compounds from protein supplements even when AA requirements are ***,implementing a low CP formulation can increase the net energy(NE)content in feeds causing excessive fat *** supplementation of functional AA,coupled with low CP formulation could further enhance intestinal health and glucose m.t.bolism,improving nitrogen utilization,and growth *** experiments were conducted to evaluate the effects of low CP formulations with supplemental AA on the intestinal health and growth performance of growing-finishing *** In Exp.1,90 pigs(19.7±1.1 kg,45 barrows and 45 gilts)were assigned to 3 treatments:CON(18.0%CP,supplementing Lys,m.t.and thr),LCP(16.0%CP,supplementing Lys,m.t.thr,trp,and Val),and LCPt(16.1%CP,LCP+0.05%SID trp).In Exp.2,72 pigs(34.2±4.2 kg BW)were assigned to 3 treatments:CON(17.7%CP,meeting the requirements of Lys,m.t.thr,and trp);LCP(15.0%CP,meeting Lys,thr,trp,m.t.Val,Ile,and Phe);and VLCP(12.8%CP,meeting Lys,thr,trp,m.t.Val,Ile,Phe,His,and Leu).In Exp.3,72 pigs(54.1±5.9 kg BW)were assigned to 3 treatments and fed experimental diets for 3 phases(grower 2,finishing 1,and finishing 2).treatments were CON(18.0%,13.8%,12.7%CP for 3 phases;meeting Lys,m.t.thr,and trp);LCP(13.5%,11.4%,10.4%CP for 3 phases;meeting Lys,thr,trp,m.t.Val,Ile,and Phe);and LCPG(14.1%,12.8%,11.1%CP for 3 phases;LCP+Glu to m.t.h SID Glu with CON).All diets had 2.6 mcal/kg *** In Exp.1,overall,the growth performance did not differ among *** LCPt increased(Pthe duodenum and *** LCP and LCPt increased(Pt-1,4F2hc,and B0At exp

关键词： Amino acids Growing-finishing pigs Growth performance Intestinal health Low crude protein formulation Net energy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent Advances in Catalytic Carbonylation Reactions in Alternative Reaction media

引用

Chinese Journal of Chemistry 2024年第4期42卷 406-429页

作者： Csaba Árvai László t.mika Department of Chemical and Environmental Process Engineering Faculty of Chemical Technology and BiotechnologyBudapest University of Technology and EconomicsMűegyetem rkp.3H-1111 BudapestHungary

Since the discovery of the hydroformylation(oxo-synthesis or Roelen reaction)and the Reppe-reaction,the transition m.t.l-catalyzed carbonylation reactions,providing versatile,facile,and even atom-economic m.t.ods for the selective incorporation of C=O functionality to various skeletons,have gained tremendous importance in synthetic organic chemistry from laboratories to industrial *** carbonylation of carbon-carbon multiple bonds,arom.t.c halides,triflates,etc.,in the presence of various nucleophiles has led the way to produce aldehydes,carboxylic acids,esters,amides,etc.,in the fine chemical ***,these protocols usually proceed in conventional,fossil-based,and usually toxic reaction ***,several attem.t. have been directed to developing efficient carbonylation m.t.ods in alternative,less harmful,non-fossil-based and even in renewable reaction *** this review,we overview the recent applications of alternative solvents such as water,biomass-based alcohols,γ-valerolactone(GVL),2-m.t.yltetrahydrofuran(2-m.t.F),ionic liquids(ILs),deep eutectic solvents(DES),alkyl levulinates,limonene,α-pinene,and dim.t.yl carbonate as well as fluorous media to improve efficiency,safety and environmentally benign nature of carbonylation protocols.

关键词： Carbonylation Catalysis Solvents Green chemistry Carbon monoxide transition m.t.ls Homogeneous catalysis Palladium

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ground-based and additional science support for SmILE

引用

Earth and Planetary Physics 2024年第1期8卷 275-298页

作者： J.A.Carter m.Dunlop C.Forsyth K.Oksavik E.Donovon A.Kavanagh S.E.milan t.Sergienko R.C.Fear D.G.Sibeck m.Connors t.Yeoman X.tan m.G.G.t.taylor K.mcWilliams J.Gjerloev R.Barnes D.D.Billet G.Chisham A.Dimmock m.P.Freeman D.-S.Han m.D.Hartinger S.-Y.W.Hsieh Z.-J.Hu m.K.James L.Juusola K.Kauristie E.A.Kronberg m.Lester J.manuel J.m.t.ka I.mcCrea Y.miyoshi J.Rae L.Ren F.Sigernes E.Spanswick K.Sterne A.Steuwer t.Sun m.-t.Walach B.Walsh C.Wang J.weygand J.Wild J.Yan J.Zhang Q.-H.Zhang Planetary Sciences Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Rutherford Appleton Laboratory Space Science Technology Facilities CouncilOxfordshireUK School of Space and Environment Beihang UniversityBeijing 100191China Key Laboratory of Space Environment monitoring and Inform.t.on Processing Ministry of Industry and Information TechnologyBeijing 100017China Department of Space and Clim.t. Physics UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK Birkeland Centre for Space Science Department of Physics and Technology.University of BergenBergenNorway Department of Physics and Astronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 British Antarctic Survey CambridgeUK Swedish Institute of Space Physics KirunaSweden west Highfield Campus University of SouthamptonUniversity RoadSO171BJUK Goddard Space Flight Center NASAGreenbeltMarylandUSA Athabasca University AthabascaCanada EStEC European Space AgencyNetherlands University of Saskatchewan SaskatoonCanada the Johns Hopkins University Applied Physics Laboratory LaurelMarylandUSA Swedish Institude of Space Physics UppsalaSE 75121Sweden tongji University Shanghai 200092China Center for Space Plasma Physics Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Polar Research Institute of China Shanghai 200136China Finnish m.t.orological Institute(FmI) Finland Department of Earth and Environmental Sciences(Geophysics) Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Canadian Space Agency MontrealCanada GFZ German Research Centre for Geosciences PotsdamGermany Nagoya University Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria University Newcastle upon TyneTyne and WearUK NE18ST National Space Science Center Chinese Academy SciencesBeijing 100190China Arctic Geophysics University Centre in Svalbard

the joint European Space Agency and Chinese Academy of Sciences Solar wind magnetosphere Ionosphere Link Explorer(SmILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere *** these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SmILE ***,we describe current community efforts to prepare for SmILE,and the benefits and context various experiments that have explicitly expressed support for SmILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these *** include constructing an online SmILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft *** anticipate growing interest and community engagement with the SmILE mission,and we welcome novel ideas and insights from.t.e solar-terrestrial community.

关键词： magnetosphere ionosphere magnetosphere-ionosphere coupling ground-based experimentation SmILE conjunctions missions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epidemiology of work-related hand and wrist injuries in a referral center: A descriptive study

引用

World Journal of Orthopedics 2024年第7期15卷 650-659页

作者： Angélica m Rodríguez Ginna P tocanchón Jessica t Villalba Luis m Pombo Aníbal A teherán Gabriel Camero-Ramos Karen P Ayala Gerhard m Acero Research Center Fundación Universitaria Juan N.CorpasBogotá111321Colombia Red Cross Cruz Roja Colombiana-Seccional Cundinamarca BogotáBogotá111221Colombia Vigilancia Epidemiológica Instituto Nacional de SaludBogotá111321Colombia

BACKGROUND Occupational hand and wrist injuries(OHWIs)account for 25%of work-related accidents in low-and middle-income *** Colombia,more than 500000 occupational accidents occurred in 2021,and although the rate declined to less than 5%in 2020 and 2021,at least one in four accidents involved a hand or wrist *** to describe the OHWIs in workers seen at the emergency room at a second-level hospital in *** An observational study was performed using data from workers who experienced OHWIs and attended a second-level hospital,between June,2020 and may,*** overall frequency of OHWIs,as well as their distribution by sociodemo-graphic,clinical,and occupational variables,are ***,association patterns between sex,anatomical area(fingers,hand,wrist),and type of job were analyzed by correspondence analysis(CA).RESULtS there were 2.101 workers treated for occupational accidents,423(20.3%)were cases of OHWIs,which mainly affected men(93.9%)with a median age of 31 years and who worked mainly in mining(75.9%).OHWIs were more common in the right upper extrem.t.(55.3%)and comprised different types of injuries,such as contusion(42.1%),laceration(27.9%),fracture(18.7%),and crush injury(15.6%).they primarily affected the phalanges(95.2%),especially those of the first finger(25.7%).the CAs showed associations between the injured anatomical area and the worker’s job that differed in men and women(explained variance>90%).CONCLUSION One out of five workers who suffered occupational accidents in Cundinamarca,Columbia had an OHWI,affecting mainly males employed in *** occupational profile is likely to lead to prolonged rehabilitation,and permanent functional *** results might be useful for adjusting preventive measures in cluster risk groups.

关键词： Accidents Occupational Epidemiology Hand injuries Wrist injuries Occupational health

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

modelling the development of biological structures displaying longitudinal geom.t.ies in vitro:culturing pluripotent stem cells on plasma-treated,growth factor-coupled polycaprolactone fibres

引用

Engineered Regeneration 2024年第1期5卷 124-138页

作者： Badwi B.Boumelhem Stuart t.Fraser Syamak Farajikhah Rachel A.Shparberg michael B.morris marcela m.m.Bilek Anyu Zhang Behnam Akhavan Simon Fleming maryanne Large School of Physics Faculty of ScienceUniversity of SydneyAustralia Sydney Nano Institute University of SydneyAustralia School of Chemical and Biomolecular Engineering University of SydneyAustralia School of medical Sciences Faculty of Medicine and HealthUniversity of SydneyAustralia School of Biomedical Engineering Faculty of EngineeringUniversity of SydneyAustralia School of Engineering University of NewcastleCallaghanNSW 2308Australia Hunter medical Research Institute(HmRI) Precision Medicine ProgramNew Lambton Heights NSW 2305Australia

many biological structures such as nerves,blood and lymphatic vessels,and muscle fibres exhibit longitudinal ge-om.t.ies with distinct cell types extending along both the length and width of internal linear *** these three-dimensional structures in vitro is challenging:the best-defined stem-cell differentiation systems are mono-layer cultures or organoids using pluripotent stem *** stem cells can differentiate into functionally m.t.re cells depending on the signals received,holding great promise for regenerative ***,the integration of in vitro differentiated cell types into diseased tissue remains a *** scaffolds can bridge this gap if the appropriate signalling systems are incorporated into the ***,we have taken a biomimicry approach to generate longitudinal structures in *** this approach,mouse embryonic stem cells are directed to differentiate to specific cell types on the surface of polycaprolactone(PCL)fibres treated by plasma-immersion ion implantation and to which with lineage-specifying molecules have been covalently *** demonstrate the simplicity and utility of our m.t.od for efficiently generating high yields of the following cell types from.t.ese pluripotent stem cells:neurons,vascular endothelial cells,osteoclasts,adipocytes,and cells of the erythroid,myeloid,and lymphoid *** arranged plasma-treated scaffolds with differentiated cell types could ultim.t.ly serve as a means for the repair or treatment of diseased or damaged tissue.

关键词： Pluripotent stem cells Lineage comm.t.ent Growth factors Biom.t.rial engineering Plasma-immersion ion implantation Covalent biomolecule attachment Polycaprolactone

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

the secondary injury cascade after spinal cord injury:an analysis of local cytokine/chemokine regulation

引用

Neural Regeneration Research 2024年第6期19卷 1308-1317页

作者： Daniel J.Hellenbrand Charles m.Quinn Zachariah J.Piper Ryan t.Elder Raveena R.mishra taylor L.marti Phoebe m.Omuro Rylie m.Roddick Jae Sung Lee William L.murphy Amgad S.Hanna Department of Neurosurgery University of Wisconsin-Madison School of Medicine and Public HealthMadisonWIUSA Department of Biomedical Engineering University of Wisconsin-MadisonMadisonWIUSA Department of Orthopedics and Rehabilitation University of Wisconsin-MadisonMadisonWIUSA Department of m.t.rials Science and Engineering University of Wisconsin-MadisonMadisonWIUSA Forward BIO Institute University of Wisconsin-MadisonMadisonWIUSA

After spinal cord injury,there is an extensive infiltration of immune cells,which exacerbates the injury and leads to further neural ***,a major aim of current research involves targeting the immune response as a treatment for spinal cord *** much research has been performed analyzing the complex inflamm.t.ry process following spinal cord injury,there remain major discrepancies within previous literature regarding the timeline of local cytokine *** objectives of this study were to establish an overview of the timeline of cytokine regulation for 2 weeks after spinal cord injury,identify sexual dimorphisms in terms of cytokine levels,and determine local cytokines that significantly change based on the severity of spinal cord *** were inflicted with either a mild contusion,moderate contusion,severe contusion,or complete transection,7 mm of spinal cord centered on the injury was harvested at varying times post-injury,and tissue homogenates were analyzed with a Cytokine/Chemokine 27-Plex *** demonstrated pro-inflamm.t.ry cytokines including tumor necrosis factorα,interleukin-1β,and interleukin-6 were all upregulated after spinal cord injury,but returned to uninjured levels within approxim.t.ly 24 hours post-injury,while chemokines including monocyte chemoattractant protein-1 remained upregulated for days *** contrast,several anti-inflamm.t.ry cytokines and growth factors including interleukin-10 and vascular endothelial growth factor were downregulated by 7 days *** spinal cord injury,tissue inhibitor of m.t.lloproteinase-1,which specifically affects astrocytes involved in glial scar development,increased more than all other cytokines tested,reaching 26.9-fold higher than uninjured *** a mild injury,11 cytokines demonstrated sexual dimorphisms;however,after a severe contusion only leptin levels were different between female and male *** conclusion,pro-inflamm.t.ry cytokines in

关键词： astrocytes chemokines cytokines inflamm.t.on macrophages microglia secondary damage spinal cord injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：