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ArF浸没式光刻胶用抗水涂层研究进展

涂料工业 2024年第4期54卷 74-81页

作者：郑祥飞徐亮陈侃刘敬成张家龙陈韦帆瑞红(苏州)电子化学品股份有限公司江苏苏州215124 江南大学化学与材料工程学院江苏无锡214122 中石化(上海)石油化工研究院有限公司上海201208

氟化氩(ArF)浸没式光刻需在光刻胶表面形成抗水涂层,阻挡光刻胶和水之间组分交换。抗水涂层对光刻胶的分辨率、工艺窗口、低缺陷要求起着重要作用,平衡抗水涂层的疏水性和碱溶性是设计聚合物结构的重点和难点。分析了形成抗水涂层的方... 详细信息

氟化氩(ArF)浸没式光刻需在光刻胶表面形成抗水涂层,阻挡光刻胶和水之间组分交换。抗水涂层对光刻胶的分辨率、工艺窗口、低缺陷要求起着重要作用,平衡抗水涂层的疏水性和碱溶性是设计聚合物结构的重点和难点。分析了形成抗水涂层的方法和成膜机理,对比了不同方法的优缺点,根据聚合物所含官能团及其碱溶性,对抗水涂层聚合物进行了分类总结,重点阐述抗水涂层聚合物的结构和性能要求,尤其关注了聚合物侧链的位阻效应和氢键作用对涂层的疏水性影响。最后对抗水涂层的应用和发展进行了展望。

关键词： ArF浸没式光刻抗水涂层疏水和碱溶性聚合物结构

The Design of Lens Imaging System byMeans of Fractional Fourier Transform

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Chinese Journal of Lasers 2002年第2期11卷 27-32页

作者： chen Jiannong XU Qiang (Department of Physics, Yantai Teachers’ University, Yantai 264025, China)D.R.Selviah(Department of Electronic and Electrical Engineering, University College London, Torrington Place, London wc1E 7JE, UK) Department of Physics Yantai Teachers' University Yantai 264025 Department of Electronic and Electrical Engineering University College London Torrington Place 英国 London WC1E 7JE

The relation between the 2nd fractional Fourier transform and the imaging process of an optical system is discussed. By changing the coordinate scales of the input plane in respect to the magnification of the optical imaging system, the fractional Fourier transform can be a powerful tool in designing specific imaging system. The Gaussian imaging formula of single lens is obtained by using the tool. Finally the procedures are generalized for designing a double-lens imaging system through an example.

关键词： lens imaging system fractional Fourier transform Gaussian imaging formula

揭示下一代高通量测序在传染病诊断中的潜力:挑战与前景

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Science Bulletin 2024年第11期69卷 1586-1589页

作者：陈宏斌詹明华刘思 Francois Balloux 王辉 Department of Clinical Laboratory Peking University People’s HospitalBeijing 100044China UCL Genetics Institute University College LondonLondon WC1E 6BTUK

Pathogen identification for infectious disease diagnosis is crucial and can be achieved through direct isolation of microbes or indirect detection based on the host immune system. Clinical metagenomic next-generation sequencing(mNGS) is an emerging technology that comprehensively analyzes genetic material(DNA and RNA) from both microbes and the host. It does not rely on prior knowledge of a pathogen's genome. This article reviews the clinical utility of mNGS in diagnosing infectious diseases and current technical difficulties.

关键词：传染病诊断 diagnosis Clinical

甘油三酯葡萄糖指数联合不同肥胖指标与糖尿病前期人群10年新发缺血性脑卒中的相关性

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海军军医大学学报 2024年第9期45卷 1113-1119页

作者：缪莹汪宇晏丕军白雪陈攀万沁西南医科大学附属医院内分泌与代谢内科泸州646000 泸州市人民医院心内科泸州646000

目的通过队列研究分析甘油三酯葡萄糖指数(TyG)联合不同肥胖指标与四川省泸州地区糖尿病前期人群10年新发缺血性脑卒中(IS)的相关性。方法选择2011年参与泸州地区流行病学调查并且符合糖尿病前期诊断的普通居民2551例,分别按基线TyG-腰... 详细信息

目的通过队列研究分析甘油三酯葡萄糖指数(TyG)联合不同肥胖指标与四川省泸州地区糖尿病前期人群10年新发缺血性脑卒中(IS)的相关性。方法选择2011年参与泸州地区流行病学调查并且符合糖尿病前期诊断的普通居民2551例,分别按基线TyG-腰围(wc)、TyG-腰围身高比(WtHR)、TyG-BMI、TyG-腰臀比(WHR)的四分位数分为第1、第2、第3、第4四分位组(Q1、Q2、Q3、Q4组),观察各组10年新发IS情况。通过多因素logistic回归分析探索TyG-wc、TyG-WtHR、TyG-WHR与新发IS的关系。结果纳入研究的2551例糖尿病前期个体在非干预性随访至第10年时,因各种原因死亡123例,死亡率为4.8%;新发IS 142例,发生率为5.6%;新发糖尿病224例,其中22例同时新发IS,占新发糖尿病患者的9.8%。按照TyG-wc、TyG-WtHR四分位数分组,糖尿病前期人群10年新发IS的发生率均为Q4组>Q3组>Q2组>Q1组,差异有统计学意义(P0.05);按照TyG-WHR四分位数分组,新发IS的发生率为Q3组>Q4组>Q2组>Q1组,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,无论在未调整任何变量的情况下还是调整多因素后,TyG-WtHR均与糖尿病前期人群新发IS相关。结论TyG-WtHR是糖尿病前期人群发生IS的危险因素,加强对高TyG-WtHR的糖尿病前期人群的分级管理或可降低IS的发生风险。

关键词：甘油三酯葡萄糖指数腰围身高比缺血性脑卒中糖尿病前期

Engineering Analysis of Strong Motion Data from Recent Earthquakes in Sichuan, China

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工程科学与技术 2018年第3期50卷 112-124页

作者： HUANG chen GALASSO Carmine Department of Civil Environmental and Geomatic Engineering University College London (UCL) London WC1E 6BT UK

Recent earthquakes in the Sichuan Province have contributed to significantly expand the existing ground-motion database for China with new,high-quality ground-motion *** study investigated the compatibility of ground-motion prediction equations(GMPEs)established by the NGA-West2 project in the US and local GMPEs for China,with respect to magnitude scaling,distance scaling,and site scaling implied by recent Chinese strong-motion *** NGA-West2 GMPEs for shallow crustal earthquakes in tectonically active regions are considerably more sophisticated than widely used previous models,particularly in *** a mixed-effects procedure,the study evaluated event terms(inter-event residuals)and intra-event residuals of Chinese data relative to the NGA-West2 *** scaling was investigated by examining trends of intra-event residuals with source-to-site *** with respect to site conditions was investigated by examining trends of intra-event residuals with soil *** study also investigated other engineering characteristics of Chinese strong ground *** particular,the records were analyzed for evidence of pulse-like forward-directivity *** elastic median response spectra of the selected stations were compared to code-mandated design spectra for various mean return *** showed that international and local GMPEs can be applied for seismic hazard analysis in Sichuan with minor modification of the regression coefficients related to the source-to-site distance and soil ***,the Chinese data attenuated faster than implied by the considered GMPEs and the differences were statistically significant in some ***-source,pulse-like ground motions were identified at two recording stations for the 2008 Wenchuan earthquake,possibly implying rupture *** median recorded spectra were consistent with the code-based spectra in terms of amplitude and *** new ground-motion data can be used to deve

关键词： ground motion prediction equations NGA-West2 project code-based spectrum pulse-like ground motions

IN718激光熔覆Co-wc/Cu复合涂层组织与摩擦学性能研究

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摩擦学学报（中英文） 2024年第6期44卷 741-751页

作者：陈国栋刘秀波刘庆帅周安张世宏中南林业科技大学材料表界面科学与技术湖南省重点实验室湖南长沙410004 安徽工业大学先进金属材料绿色制备与表面技术教育部重点实验室安徽马鞍山243002

为提高IN718高温合金运动部件在极端环境中的服役寿命,采用激光熔覆在其表面制备了Co (S1)、Co-5%wc-5%Cu (S2)和Co-5%wc-15%Cu (S3)(质量分数)这3种耐磨减摩复合涂层,系统分析了复合涂层的显微硬度以及室温(RT)和600℃环境中的摩擦学性... 详细信息

为提高IN718高温合金运动部件在极端环境中的服役寿命,采用激光熔覆在其表面制备了Co (S1)、Co-5%wc-5%Cu (S2)和Co-5%wc-15%Cu (S3)(质量分数)这3种耐磨减摩复合涂层,系统分析了复合涂层的显微硬度以及室温(RT)和600℃环境中的摩擦学性能.结果表明:溶解的wc重新凝固析出碳化物,起到第二相强化的作用,未溶解的wc边缘析出针状物与Co基基体稳固结合.在室温下Cu可以充当固体润滑剂(Cu膜),在600℃下由CuO氧化膜以及Cu膜起减摩作用. 3种涂层的显微硬度均是基体(268.89HV0.5)的1.7倍以上,分别是478.69HV0.5、481.73HV0.5和458.51HV0.5.摩擦学性能明显优于基体,其中S2涂层在室温和600℃环境下均拥有优异的耐磨性,分别提高84.4%和64.9%,减摩效果最好的是S2涂层(RT)和S3涂层(600℃),分别提高26.9%和26.7%.室温下3种复合涂层的磨损行为由氧化和疲劳磨损主导,600℃时由氧化和黏着磨损主导.

关键词： IN718合金复合涂层激光熔覆摩擦学性能高温

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Tamoxifen对真皮成纤维细胞种植胶原网格的抑制效应

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中华整形外科杂志 2002年第3期18卷 160-162页

作者：胡大海朱雄翔徐明达陈璧 Margaret AH George wc 第四军医大学西京医院烧伤科英国牛津大学丘吉尔医院创面愈合研究所

目的　探索Tamoxifen用于治疗皮肤瘢痕挛缩的可能性。方法　将人真皮成纤维细胞种植于Ⅰ型胶原构成的胶原网格内培养 ,加入 1～ 5 0 μmol L的Tamoxifen ,测定网格收缩率 ;采用MTT染色法原位观察网格内的细胞形态及活力变化。结果　Tamo... 详细信息

目的　探索Tamoxifen用于治疗皮肤瘢痕挛缩的可能性。方法　将人真皮成纤维细胞种植于Ⅰ型胶原构成的胶原网格内培养 ,加入 1～ 5 0 μmol L的Tamoxifen ,测定网格收缩率 ;采用MTT染色法原位观察网格内的细胞形态及活力变化。结果　Tamoxifen对胶原网格收缩具有抑制效应 ,其浓度低于 5 μmol L时对网格收缩无影响 ,高于 30 μmol L时网格收缩被不可逆性完全抑制 ,处于 10～ 2 0 μmol L时对网格收缩作用呈现剂量及时间依赖性抑制。MTT染色后观察显示网格收缩变化与处于三维培养的细胞突起伸展状态相关 ;Tamoxifen并不直接导致网格内的细胞死亡 ,而是通过抑制细胞功能发挥作用。结论　Tamoxifen可对真皮成纤维细胞体外模拟的瘢痕挛缩产生抑制效应。

关键词： Tamoxifen 成纤维细胞 T型胶原三维培养瘢痕

Novel confinement combustion method of nanosized wc/C for efficient electrocatalytic oxygen reduction

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International Journal of Minerals,Metallurgy and Materials 2022年第8期29卷 1627-1634页

作者： Pengqi chen Yunxiao Tai Huan Wu Yufei Gao Jiayu chen Jigui cheng School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China National-Local Joint Engineering Research Centre of Nonferrous Metals and Processing Technology Hefei University of TechnologyHefei 230009China AECC Commercial Aircraft Engine Co. Ltd.Shanghai 200241China Research Centre for Powder Metallurgy Engineering and Technology of Anhui Province Hefei 230009China

Nanosized tungsten carbide(wc)/carbon(C)catalyst was synthesized via a novel ultra-rapid confinement combustion synthesis *** amount of activated carbon(AC)plays an important role in the morphology and structure,controlling both the precursor and final *** wc particles synthesized inside the pores of the AC had been 10-20 nm because of the confinement of the pore structure and the large specific surface area of *** used for oxygen reduction performance,the half-wave potential was−0.24 V,and the electron transfer number was 3.45,indicating the main reaction process was the transfer of four *** detailed electrocatalytic performance and underlying mechanism were investigated in this *** study provides a novel approach for the design of catalysts with new compositions and new structures,which are significant for promoting the commercialization of fuel cells.

关键词： confinement combustion synthesis tungsten carbide activated carbon electrochemical catalysis oxygen reduction reaction

BI-GreenNet:Learning Green’s Functions by Boundary Integral Network

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Communications in Mathematics and Statistics 2023年第1期11卷 103-129页

作者： Guochang Lin Fukai chen Pipi Hu Xiang chen Junqing chen Jun Wang Zuoqiang Shi Yau Mathematical Sciences Center Tsinghua UniversityBeijing 100084People’s Republic of China Department of Mathematical Sciences Tsinghua UniversityBeijing 100084People’s Republic of China Yanqi Lake Beijing Institute of Mathematical Sciences and Applications Beijing 101408People’s Republic of China Noah’s Ark Lab HuaweiNo.3 Xinxi RoadBeijing 100085People’s Republic of China University College London London WC1E 6EAUK

Green’s function plays a significant role in both theoretical analysis and numerical computing of partial differential equations(PDEs).However,in most cases,Green’s function is difficult to *** troubles arise in the following ***,compared with the original PDE,the dimension of Green’s function is doubled,making it impossible to be handled by traditional mesh-based ***,Green’s function usually contains singularities which increase in the difficulty to get a good ***,the computational domain may be very complex or even *** override these problems,we develop a new framework for computing Green’s function leveraging the fundamental solution,boundary integral method and neural networkswith reasonably high accuracy in this *** focus on Green’s function of Poisson and Helmholtz equations in bounded domains,unbounded *** also consider Poisson equation and Helmholtz equations in domains with *** numerical experiments illustrate the efficiency and accuracy of our method for solving Green’s *** addition,Green’s function provides the operator from the source term and boundary condition to *** applyGreen’s function to solve PDEs with different sources,and obtain reasonably high-precision solutions,which shows the good generalization ability of our ***,the requirements for explicit fundamental solutions to remove the singularity of Green’s function hinder the application of our method in more complex PDEs,such as variable coefficient equations,which will be investigated in our future work.

关键词： Green’s function Partial differential equation Boundary integral Neural network