检索结果-南通市图书馆

Phosphorylation of alphaB-crystallin in epiretinal membrane of human proliferative diabetic retinopathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2016年第8期9卷 1100-1105页

作者： Yoko Dong Zhenyu Dong Satoru Kase Ryo Ando Junichi Fukuhara Satoshi Kinoshita Saori Inafuku Yoshiaki Tagawa Erdal Tan Ishizuka wataru saito Miyuki Murata Atsuhiro Kanda Kousuke Noda Susumu Ishida Laboratory of Ocular Cell Biology and Visual Science Department of Ophthalmology Hokkaido University Graduate School of Medicine

AIMTo examine phosphorylation of alphaB-crystallin (p-αBC), a vascular endothelial growth factor (VEGF) chaperone, and immunohistochemically investigate relationship between p-αBC, VEGF and phosphorylated p38-mitogen-activated protein kinase (p-p38 MAPK) in the epiretinal membrane of human proliferative diabetic retinopathy (PDR).METHODSEleven epiretinal membranes of PDR surgically excised were included in this study. Two normal retinas were also collected from enucleation tissues due to choroidal melanoma. Paraformaldehyde-fixed, paraffin-embedded tissue sections were processed for immunohistochemistry with anti-p-αBC, VEGF, CD31, and p-p38 MAPK *** for p-αBC was observed in all of the epiretinal membranes examined, where phosphorylation on serine (Ser) 59 showed strongest immunoreactivity in over 70% of the membranes. The immunolocalization of p-αBC was detected in the CD31-positive endothelial cells, and co-localized with VEGF and p-p38 MAPK in PDR membranes. Immunoreactivity for p-αBC, however, was undetectable in endothelial cells of the normal retinas, where p-p38 MAPK immunoreactivity was less marked than PDR *** of αBC, in particular, phosphorylation on Ser59 by p-p38 MAPK may play a potential role as a molecular chaperon for VEGF in the pathogenesis of epiretinal membranes in PDR.

关键词： phosphorylated alphaB-crystallin vascular endothelial growth factor neovascularization proliferative diabetic retinopathy

Natural Convection Melting in a Rectangular Heat Storage Tank of Carbon Nanotube Dispersed Latent Heat Storage Material

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第3期33卷 847-855页

作者： Shin-ichi MORITA Tomoya saito Kazunori TAKAI Yasutaka HAYAMIZU Naoto HARUKI Division of Mechanical and Electrical Engineering Kitami Institute of Technology165 Koen-choKitami-shiHokkaido090-8507Japan National Institute of Technology Yonago College4448 Hikona-cyoYonago-shiTottori683-8502Japan Okayama Prefectural University 111 KubokiSoja-shiOkayama719-1197Japan

A dispersion system fluid can convect even if the dispersoid is a solid ***,heat exchange performance can be improved while maintaining fluidity using a material with high thermal conductivity as the *** study presents the melting performance evaluation results of a latent heat storage material with a carbon nanotube(CNT)dispersion system with high thermal conductivity,which enhances the thermal conductivity of the latent heat storage material and does not limit free *** the thermal conductivity and enhancing the melting convection of the heat storage material result in increased latent heat storage *** this study,the thermal conductivity of the latent heat storage material was successfully increased by dispersing CNTs in the *** 0.1%(in mass)of multi-wall CNT(MWCNT)was dispersed in a paraffin-based latent heat storage material,the shear stress increased by 1.5 times at a shear rate of 500 s^(-1),while taking into account the potential effects of convective ***,a latent heat storage experiment was conducted in a rectangular heat storage tank using the CNT dispersion composition ratio as a parameter.A rectangular vessel with a heated vertical surface was used for the latent heat storage *** melting speed was determined by comparing the amount of latent heat stored in a CNT-dispersed latent heat storage material and a single-phase latent heat storage material *** experimental results show that the time required for the latent heat storage material to completely melt in the heat storage tank was the shortest for the single-phase latent heat storage material ***,the fastest melting progress was observed for the sample with 0.02%(in mass)MWCNT content in the melting rate range of up to approximately 40%in the *** results indicate that this phenomenon is caused by the difference in the melting rates in the upper part of the *** generated data are useful for det

关键词： latent heat storage phase change carbon nano tube free convection heat transfer

维普期刊数据库

Assessment of corrected time-step method for nominal ionospheric gradient calculation: A comparative analysis with spatial approaches

在线全文

学校读者我要写书评

暂无评论

Earth and Planetary Physics 2024年第4期8卷 641-649页

作者： Slamet Supriadi Prayitno Abadi Susumu saito Harry Bangkit Dwiko Unggul Prabowo Adi Purwono Ginaldi Ari Nugroho Research Center for Smart Mechatronics National Research and Innovation Agency(BRIN)BandungIndonesia Research Center for Climate and Atmosphere BRINBandungIndonesia School of Electrical Engineering Telkom UniversityKab.BandungIndonesia Electronic Navigation Research Institute National Institute of MaritimePort and Aviation TechnologyTokyoJapan Research Center for Space BRINBandungIndonesia

The effect of ionospheric delay on the ground-based augmentation system under normal conditions can be mitigated by determining the value of the nominal ionospheric gradient(σvig).The nominal ionospheric gradient is generally obtained from Continuously Operating Reference Stations data by using the spatial single-difference method(mixed-pair,station-pair,or satellite-pair)or the temporal single-difference method(time-step).The time-step method uses only a single receiver,but it still contains ionospheric temporal *** introduce a corrected time-step method using a fixed-ionospheric pierce point from the geostationary equatorial orbit satellite and test it through simulations based on the global ionospheric *** also investigate the effect of satellite paths on the corrected time-step method in the region of the equator,which tends to be in a more north–south direction and to have less coverage for the east–west ionospheric *** study also addresses the limitations of temporal variation correction coverage and recommends using only the correction from *** processes are developed under simulations because observational data are still difficult to *** findings demonstrate that the corrected time-step method yieldsσvig values consistent with other approaches.

关键词： ground-based augmentation system nominal ionospheric gradient time-step correction global ionospheric model

维普期刊数据库

Hyperacute experimental model of rat lung transplantation using a coronary shunt cannula

在线全文

学校读者我要写书评

暂无评论

World Journal of Transplantation 2024年第2期14卷 155-161页

作者： Munehisa Takata Yusuke Tanaka Daisuke saito Shuhei Yoshida Isao Matsumoto Department of Thoracic Surgery Kanazawa UniversityKanazawa 920-8641IshikawaJapan

BACKGROUND Lung transplantation is a well-established treatment of end-stage lung disease.A rodent model is an inexpensive way to collect biological data from a living model after lung ***,mastering the surgical technique takes time owing to the small organ *** To conduct rat lung transplantation using a shunt cannula(SC)or modified cannula(MC)and assess their *** Rat lung transplantation was performed in 11 animals in the SC group and 12 in the MC *** devised a method of rat lung transplantation using a coronary SC for coronary artery bypass surgery as an anastomosis of pulmonary arteri-ovenous vessels and *** same surgeon performed all surgical proce-dures in the donor and recipient rats without using a magnifying *** success rate of lung transplantation,operating time,and PaO2 values were com-pared after 2-h reperfusion after *** Ten and 12 lungs were successfully transplanted in the SC and MC groups,*** the SC group,one animal had cardiac arrest within 1 h after reperfusion owing to bleeding during pulmonary vein *** opera-ting time for the removal of the heart-lung block from the donor and preparation of the left lung graft was 26.8±2.3 and 25.7±1.3 min in the SC and MC groups,respectively(P=0.21).The time required for left lung transplantation in the recipients was 37.5±2.8 min and 35.9±1.4 min in the SC and MC groups,respectively(P=0.12).PaO2 values at 2 h after reperfusion were 456.2±25.5 and INTRODUCTION Lung transplantation is a well-established treatment of end-stage lung *** immune and non-immune mech-anisms in lung transplantation are highly complex,and post-transplant complications such as infections and primary and chronic lung allograft dysfunction must be reduced to improve ***,there is a need for immunological and pathophysiological analyses using animal lung transplantation *** rat lung transplantation model was f

关键词： Lung transplantation Rat Shunt cannula Modified cannula Reperfusion

Evaluating mechanism of banana pseudo-stem retting using seawater:A cost-effective surface pre-treatment approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Bioresources and Bioproducts 2024年第3期9卷 322-335页

作者： Prince Hotor Ahmed H.Hassanin Osbert Akatwijuka Mohamed A.H.Gepreel Mitsuo Yamamoto Yukie saito Ahmed Abdel-Mawgood Egypt-Japan University of Science and Technology Biotechnology ProgramAlexandria GovernorateNew Borg Al Arab 21934Egypt Alexandria University Department of Textile EngineeringAlexandria GovernorateBab Sharqi 5424041Egypt Egypt-Japan University of Science and Technology Material Science and EngineeringAlexandria GovernorateNew Borg Al Arab 21934Egypt Graduate School of Agricultural and Life Sciences The University of TokyoBunkyo-KuTokyo 113-8657Japan

Retting has been employed to extract natural fibers from agricultural wastes as a biological and cost-effective approach for *** its global abundance,banana pseudo-stem is a promising agro-waste for lignocellulosic fiber *** this study,fibers were extracted from the pseudo-stems after being pre-treated under four conditions using seawater at room temperature for up to 35 d Bacterial isolation from the fresh seawater sample and screening for ligninolytic ability were *** load as well as laccase and manganese peroxidase enzyme activity profile assay during the retting duration were *** transform infrared(FT-IR)and X-day diffraction(XRD)analyses were also examined for both pre-treated and untreated extracted *** results shows that six out of the eight bacterial isolates had the ability to degrade *** treatments(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)recorded the highest viable bacterial load of 9.24×102 and 4.46×102 CFU,respectively,on the 14th day of the retting ***,the highest laccase and manganese peroxidase enzymes activity was recorded for(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)treatments in the second to the third *** FT-IR spectra of the pre-treated fibers revealed relative reductions in peaks attributed to polysaccharides and other amorphous substances for all retting *** XRD diffractogram revealed that the crystallinity index(CI)of pre-treated fibers increased in all seawater retting treatment ***,the CI for fibers pre-treated under enzymatic conditions were enhanced even after five *** analysis for selected bacterial isolates showed homology to sequences of Bacillus velezensis,Shewanella sp.L8–5,and Citrobacter amalonaticus and Bacillus subtilis j8 *** these findings,it was suggested that physical,biological,and chemical actions were collectively involved in the seawater retting process of banana ps

关键词： Seawater retting Banana pseudo-stem Natural fiber Enzyme activity Colony forming unit

Ultrasound-guided peripheral nerve blocks for anterior cutaneous nerve entrapment syndrome after robot-assisted gastrectomy: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第8期16卷 2719-2723页

作者： Yukiko saito Hirohisa Takeuchi Joho Tokumine Ryuji Sawada Kunitaro Watanabe Tomoko Yorozu Department of Anesthesiology Kyorin University School of MedicineTokyo 181-8611Japan Department of Surgery Kyorin University School of MedicineTokyo 181-8611Japan

BACKGROUND Anterior cutaneous nerve entrapment syndrome(ACNES)is a condition mani-festing with pain caused by strangulation of the anterior cutaneous branch of the lower intercostal *** case report aims to provide new insight into the selection of peripheral nerve blocks for the ACNES *** SUMMARY A 66-year-old woman manifested ACNES after a robot-assisted distal *** ultrasound-guided rectal sheath block was effective for pain triggered by the port ***,the sudden severe pain,which radiated laterally from the previous site,remained.A transversus abdominis plane block was performed for the remaining pain and effectively relieved *** In this case,the trocar port was inserted between the rectus and transverse abdominis *** intercostal nerves might have been entrapped on both sides of the rectus and transversus abdominis ***,rectus sheath and transverse abdominis plane blocks were required to achieve complete pain *** the best of our knowledge,this is the first report on use of a combination of rectus sheath and transverse abdominis plane blocks for pain relief in ACNES.

关键词： Anterior cutaneous nerve entrapment syndrome Rectus sheath block Trans-verse abdominal plane block Hydrodissection Robot-assisted gastrectomy Case report

Exploiting open source omics data to advance pancreas research

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pancreatology 2024年第1期7卷 21-27页

作者： Gayathri Swaminathan Toshie saito Sohail Z.Husain Division of Gastroenterology Hepatology and NutritionDepartment of PediatricsStanford University School of MedicineStanfordCA

The"omics"revolution has transformed the biomedical research landscape by equipping scientists with the ability to interrogate complex biological phenomenon and disease processes at an unprecedented *** volume of"big"data generated by the different omics studies such as genomics,transcriptomics,proteomics,and metabolomics has led to the concurrent development of computational tools to enable in silico analysis and aid data *** the intensive resources and high costs required to generate and analyze big data,there has been centralized,collaborative efforts to make the data and analysis tools freely available as"Open Source,"to benefit the wider research *** research studies have contributed to this"big data rush"and have additionally benefitted from utilizing the open source data as evidenced by the increasing number of new research findings and publications that stem from such *** this review,we briefly introduce the evolution of open source omics data,data types,the"FAIR"guiding principles for data management and reuse,and centralized platforms that enable free and fair data accessibility,availability,and provide tools for omics data *** illustrate,through the case study of our own experience in mining pancreatitis omics data,the power of repurposing open source data to answer translationally relevant questions in pancreas research.

关键词： Gene expression Omics Open source data Pancreatitis

维普期刊数据库

Transformed gastric mucosa-associated lymphoid tissue lymphoma originating in the colon and developing metachronously after Helicobacter pylori eradication:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第10期16卷 4281-4288页

作者： Makoto saito Zen-Ichi Tanei Masumi Tsuda Toma Suzuki Emi Yokoyama Minoru Kanaya Koh Izumiyama Akio Mori Masanobu Morioka Takeshi Kondo Blood Disorders Center Aiiku HospitalSapporo 064-0804HokkaidoJapan Department of Cancer Pathology Faculty of MedicineHokkaido UniversitySapporo 060-8638HokkaidoJapan

BACKGROUND Helicobacter pylori(***)eradication treatment for primary gastric mucosaassociated lymphoid tissue(MALT)lymphoma has already been ***,t(11;18)(q21;q21)/API2-MALT1 translocation-positive lesions are a type of primary gastric MALT lymphoma in which a response to eradication treatment is difficult to *** addition,trisomy 18 may be associated with diffuse large B-cell lymphoma(DLBCL)transformation of gastric MALT *** SUMMARY A 66-year-old man was diagnosed with MALT lymphoma in the ascending colon by colonoscopy and *** years later,esophagogastroduodenoscopy revealed chronic atrophic gastritis that was positive for ***,and eradication treatment was *** years and nine months later(at the age of 70),a new ulcerative lesion suggestive of MALT lymphoma appeared in the gastric body,and six months later,a similar lesion was also found in the *** year later(4 years and 3 months after *** eradication),at the age of 72,the lesion in the gastric body had become deeper and had propagated.A biopsy revealed a pathological diagnosis of *** MALT lymphoma lesions in the ascending colon and DLBCL lesions in the stomach were positive for the t(11;18)(q21;q21)/API2-MALT1 translocation,and trisomy 18q21 was also *** 6 courses of R-CHOP(rituximab,cyclophosphamide,doxorubicin,vincristine and prednisone)chemotherapy,all of the above lesions disappeared[complete remission(CR)],and CR has been maintained for more than 3 *** addition,both the colonic and gastric lesions were proven to have the same *** Because the patient had a MALT1 translocation with trisomy 18q21,it was thought that this gastric MALT lymphoma developed independently of *** infection and progressed.

关键词： Gastric mucosa-associated lymphoid tissue lymphoma Transform Diffuse large B-cell lymphoma Colonic mucosa-associated lymphoid tissue lymphoma Helicobacter pylori eradication MALT1 translocation Case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于离子液体的深度除湿技术及应用探索

工程热物理学报 2024年第10期 2958-2964页

作者：曹博文殷勇高 Giannetti Niccolo saito Kiyoshi 东南大学能源与环境学院低碳型建筑环境设备与系统节能教育部工程研究中心早稻田大学基础科学与工程研究生院早稻田大学早稻田高等研究所早稻田大学应用力学和航空航天工程系

液体深度除湿是实现低湿度行业低碳转型的一种有效途径。目前，具有深度除湿潜力(极低蒸气压、非结晶和无腐蚀)的离子液体是传统盐溶液的理想替代。本研究搭建了离子液体深度除湿实验平台，并分析了不同运行工况下的除湿性能。结果表明... 详细信息

液体深度除湿是实现低湿度行业低碳转型的一种有效途径。目前，具有深度除湿潜力(极低蒸气压、非结晶和无腐蚀)的离子液体是传统盐溶液的理想替代。本研究搭建了离子液体深度除湿实验平台，并分析了不同运行工况下的除湿性能。结果表明：降膜/鼓泡吸收方式均能实现较高的深度除湿效果，最低出风含湿量可降至2.0 g/kg(da)以下。同时，对于进口含湿量为3.3 g/kg(da)的低湿工况，降膜装置的除湿效率仅为40%左右。然而，鼓泡装置的除湿效率可达到81%，有效开发了离子液体的深度除湿潜力。此外，总结了两种吸收方式的先进性与适用性，为离子液体深度除湿技术的应用提供指导。

关键词：深度除湿离子液体除湿性能实验研究