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Observability of parameter space for charged Higgs boson in its bosonic decays in two Higgs doublet model Type-1

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Chinese Physics C 2024年第2期48卷 57-65页

作者： Ijaz Ahmed waqas ahmad M.S.Amjad Jamil Muhammad Federal Urdu University of Arts Science and TechnologyIslamabad Pakistan Riphah International University Sector I-14Hajj ComplexIslamabad Pakistan National University of Technology Islamabad Pakistan Sang-Ho College and Department of PhysicsKonkuk UniversitySeoul 05029South Korea

This study explores the possibility of discovering H±through its bosonic decays,i.e.,H±→W±φ(whereφ=h or A),within the Type-I two Higgs doublet model(2HDM).The main objective is to demonstrate the available parameter space after applying recent experimental and theoretical exclusion *** suggest that mH±=150 GeV is the most probable mass for the H±→W±φdecay channel in pp collisions at s1/2=8,13,and 14 *** also report on the application of a modern machine learning approach to a multivariate technique for heavy charged Higgs production in association with a single top quark through weak interaction to demonstrate its observability in comparison with the most relevant Standard Model backgrounds using the neural networks of boosted decision Tree(BDT),likelihood(LH),and multilayer perceptron(MLP).

关键词： charged Higgs MSSM LHC

Oxidative desulfurization of dibenzothiophene over Fe promoted Co–Mo/Al_2O_3 and Ni–Mo/Al_2O_3 catalysts using hydrogen peroxide and formic acid as oxidants

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Chinese Journal of Chemical Engineering 2018年第3期26卷 593-600页

作者： Yaseen Muhammad Ayesha Shoukat Ata Ur Rahman Haroon Ur Rashid waqas ahmad Institute of Chemical Sciences University ofPeshawar Khyber Pakhtunkhwa Pakistan School of Chemistry and Chemical Engineering Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology Guangxi University Guangxi 530004 China Department of Chemistry 5arhad University of Science and Information Technology Peshawar Pakistan

This work reports the enhancing effect of a highly cost effective and efficient metal, Fe, incorporation to Co or Ni based Mo/Al2O3 catalysts in the oxidative desulfurization （ODS） of dibenzothiophene （DBT） using H2O2 and formic acid as oxidants. The influence of operating parameters i.e. reaction time, catalyst dose, reaction temperature and oxidant amount on oxidation process was investigated. Results revealed that 99% DBT conversion was achieved at 60℃ and 150 min reaction time over Fe-Ni-Mo/Al2O3. Fe tremendously enhanced the ODS activity of Co or Ni based Mo/Al2O3 catalysts following the activity order：Fe-Ni-Mo/Al2O3 〉 Fe-Co-Mo/Al2O3 〉 Ni-Mo/Al2O3 〉 Co-Mo/Al2O3, while H2O2 exhibited higher oxidation activity than formic acid over all catalyst systems. Insight about the surface morphology and textural properties of fresh and spent catalysts were achieved using scanning electron microscopy （SEM）, X-ray diffraction （XRD）, energy dispersive X-ray （EDX） analysis, Atomic Absorption Spectroscopy （AAS） and BET surface area analysis, which helped in the interpretation of experimental data. The present study can be deemed as an effective approach on industrial level for ODS of fuel oils crediting to its high efficiency, low process/catalyst cost, safety and mild operating condition.

关键词： Oxidative desulfurization Fuel oil Dibenzothiophene Fe promoted (Co/Ni)-Mo/Al2O3 catalyst XRD

Carbon Monoxide Modulates Auxin Transport and Nitric Oxide Signaling in Plants under Iron Deficiency Stress

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Phyton-International Journal of Experimental Botany 2024年第1期93卷 45-61页

作者： Kaiyue Hong Yasmina Radani waqas ahmad Ping Li Yuming Luo Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake Jiangsu Collaborative Innovation Center of Regional Modern Agriculture and Environmental ProtectionHuaiyin Normal UniversityHuaian223300China School of Life Sciences Nanjing Forestry UniversityNanjing210037China School of Life Sciences Shanghai UniversityShanghai200444China

Carbon monoxide(CO)and nitric oxide(NO)are signal molecules that enhance plant adaptation to environmental *** is an essential phytohormone for plant growth and *** and NO play crucial roles in modulating the plant’s response to iron *** deficiency leads to an increase in the activity of heme oxygenase(HO)and the subsequent generation of ***,it alters the polar subcellular distribution of Pin-Formed 1(PIN1)proteins,resulting in enhanced auxin *** alteration,in turn,leads to an increase in NO ***,iron deficiency enhances the activity of ferric chelate reductase(FCR),as well as the expression of the Fer-like iron deficiency-induced transcription factor 1(FIT)and the ferric reduction oxidase 2(FRO2)genes in plant *** of the long hypocotyl 1(HY1)gene,which encodes heme oxygenase,or the CO donor treatment resulted in enhanced basipetal auxin transport,higher FCR activity,and the expression of FIT and FRO2 genes under Fe ***,a potential mechanism is proposed:CO and NO interact with auxin to address iron deficiency *** alters auxin transport,enhancing its accumulation in roots and up-regulating key iron-related genes like FRO2 and *** auxin levels affect NO signaling,leading to greater sensitivity in root *** interplay promotes FCR activity,which is crucial for iron ***,these molecules enhance iron uptake and root growth,revealing a novel aspect of plant physiology in adapting to environmental stress.

关键词： Carbon monoxide nitric oxide auxin iron deficiency signal molecule plants

An Optimal Dispatch Strategy for Distributed Microgrids Using PSO

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CSEE Journal of Power and Energy Systems 2020年第3期6卷 724-734页

作者： Muhammad Yousif Qian Ai Yang Gao waqas ahmad Wattoo Ziqing Jiang Ran Hao Key Laboratory of Control of Power Transmission and Conversion(SJTU) Ministry of EducationShanghai 200240China Department of Electrical and Computer Engineering COMSATS University Islamabad(CUI)Sahiwal campusPunjab 57000Pakistan

Grid structures are rapidly evolving in view of contemporary energy policies which ensure the addition of more renewable sources to reduce the carbon *** to a centralized approach,low voltage grids(decentralized and distributed)are promising approaches to integrating nondispatchable renewable energy sources(RESs).Installing local micro level power generation sources such as fuel cells,microturbines,and energy storage systems are a recent trend which helps in the intermittent effects of RESs and makes microgrids less dependable on the main *** to the increasing variety of distributed generation sources having diverse characteristics,power dispatch scheduling of distributed microgrids is becoming challenging.A dispatch scheduling solution from an operator’s point of view is presented by the *** core objective of this study is to minimize the carbon emissions and the cost of each ***,it is observed that sales and purchases from the main grid are ***,transmission losses are also decreased.

关键词： Energy management system microgrid multimicrogrid power dispatch PSO Power scheduling strategy

Rabies virus co-localizes with early(Rab5) and late(Rab7) endosomal proteins in neuronal and SH-SY5Y cells

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Virologica Sinica 2017年第3期32卷 207-215页

作者： waqas ahmad Yingying Li Yidi Guo Xinyu Wang Ming Duan Zhenhong Guan Zengshan Liu Maolin Zhang Key Laboratory of Zoonosis Research Ministry of Education Institute of Zoonosis College of Veterinary Medicine Jilin University Section of Epidemiology and Public Health College of Veterinary and Animal Sciences

Rabies virus(RABV) is a highly neurotropic virus that follows clathrin-mediated endocytosis and p H-dependent pathway for trafficking and invasion into endothelial cells. Early(Rab5, EEA1) and late(Rab7, LAMP1) endosomal proteins play critical roles in endosomal sorting, maturity and targeting various molecular cargoes, but their precise functions in the early stage of RABV neuronal infection remain elusive. In this study, the relationship between enigmatic entry of RABV with these endosomal proteins into neuronal and SH-SY5 Y cells was ***, TCID_(50) titers, electron microscopy and western blotting were carried out to determine the molecular interaction of the nucleoprotein(N) of RABV with early or late endosomal proteins in these cell lines. The expression of N was also determined by down-regulating Rab5 and Rab7 in both cell lines through RNA interference. The results were indicative that N proficiently colocalized with Rab5/EEA1 and Rab7/LAMP1 in both cell lines at 24 and 48 h post-infection, while N titers significantly decreased in early infection of RABV. Down-regulation of Rab5 and Rab7 did not inhibit N expression, but it prevented productive infection via blocking the normal trafficking of RABV in a low pH environment. Ultrathin sections of cells studied by electron microscope also verified the close association of RABV with Rab5 and Rab7 in neurons. From the data it was concluded that primary entry of RABV strongly correlates with the kinetics of Rab-proteins present on early and late vesicles, which provides helpful clues to explain the early events of RABV in nerve cells.

关键词： Rab5 Rab7 rabies virus(RABV) endosomes colocalization

Desulphurization of Transportation Fuels by Per-Formic Acid Oxidant Using MoOx Loaded on ZSM-5 Catalyst

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Journal of Power and Energy Engineering 2017年第12期5卷 87-99页

作者： waqas ahmad Imtiaz ahmad Institute of Chemical Sciences University of Peshawar Peshawar Pakistan

Desulphurization of model and real oil samples was investigated using performic acid as oxidant assisted by air as co-oxidant. The catalysts used were Mo-oxide supported on ZSM-5 zeolite, which was synthesized in the laboratory and characterized by FT-IR, XRD, SEM and SSA analysis. In case of model oil, the optimum condition determined for complete oxidation of all the model compounds including thiophene, DBT and 4,6-DMDBT were;60?C, 60 min, ambient pressure and air flow rate of 100 mL/min. The oxidation reactivity decreased from 4,6-DMDBT to DBT and thiophene, which was found to follow pseudo first order kinetics. The real oil sample used in the study included untreated naphtha (NP), light gas oil (LGO), heavy gas oil (HGO) and Athabasca bitumen (Bit.). In case of NP and LGO the sulfur removal of above 78% was attained whereas in case of HGO and Bit. samples about 60% of desulfurization was achieved.

关键词： Molybdenum Oxide NH4-ZSM-5 Oxidative Desulphurization Air Oxidation Performic Acid Model Sulfur Compounds Wet-Impregnation

Wnt signaling pathway inhibitor promotes mesenchymal stem cells differentiation into cardiac progenitor cells in vitro and improves cardiomyopathy in vivo

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World Journal of Stem Cells 2023年第8期15卷 821-841页

作者： Rabbia Muneer Rida-e-Maria Qazi Abiha Fatima waqas ahmad Asmat Salim Luciana Dini Irfan Khan Dr.Panjwani Center for Molecular Medicine and Drug Research International Center for Chemical and Biological SciencesUniversity of KarachiKarachi 75270SindhPakistan Department of Biology and Biotechnologies Charles Darwin Sapienza University of RomeRome 00185Italy

BACKGROUND Cardiovascular diseases particularly myocardial infarction(MI)are the leading cause of mortality and morbidity around the *** cardiac tissue possesses very limited regeneration potential,therefore use of a potent small molecule,inhibitor Wnt production-4(IWP-4)for stem cell differentiation into cardiomyocytes could be a promising approach for cardiac *** pathway inhibitors may help stem cells in their fate determination towards cardiomyogenic lineage and provide better homing and survival of cells in *** stem cells(MSCs)derived from the human umbilical cord have the potential to regenerate cardiac tissue,as they are easy to isolate and possess multilineage differentiation ***-4 may promote the differentiation of MSCs into the cardiac *** To evaluate the cardiac differentiation ability of IWP-4 and its subsequent in vivo *** Umbilical cord tissue of human origin was utilized to isolate the MSCs which were characterized by their morphology,immunophenotyping of surface markers specific to MSCs,as well as by tri-lineage differentiation *** analysis was performed to identify the optimal concentration of *** were treated with 5μM IWP-4 at two different time *** of MSCs into cardiomyocytes was evaluated at DNA and protein *** MI ratmodel was ***-4 treated as well as untreated MSCs were implanted in the MI model,then the cardiac function was analyzed via *** were labeled with 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate(DiI)dye for tracking,while the regeneration of infarcted myocardium was examined by histology and *** MSCs were isolated and *** analysis showed that IWP-4 was non-cytotoxic at 5μM *** specific gene and protein expression analyses exhibited more remarkable results in fourteen days treated group that was eventually sel

关键词： Myocardial infarction Inhibitor Wnt production-4 Differentiation Mesenchymal stem cells Wnt pathway Cardiac function

Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model

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World Journal of Stem Cells 2022年第8期14卷 633-657页

作者： Rida-e-Maria Qazi Irfan Khan Kanwal Haneef Tuba Shakil Malick Nadia Naeem waqas ahmad Asmat Salim Sadia Mohsin Stem Cell Laboratory Dr.Panjwani Center for Molecular Medicine and Drug ResearchICCBSUniversity of KarachiKarachi 75270SindhPakistan Dr.Zafar H.Zaidi Center for Proteomics University of KarachiKarachi 75270SindhPakistan Dow Research Institute of Biotechnology and Biomedical Sciences(DRIBBS) Dow University of Health and SciencesOjha CampusKarachi 74200SindhPakistan Cardiovascular Research Center Lewis Katz School of MedicineTemple UniversityPhiladelphiaPA 19140United States

BACKGROUND Cardiovascular diseases are the major cause of mortality *** of the damaged myocardium remains a challenge due to mechanical constraints and limited healing ability of the adult heart *** tissue engineering using biomaterial scaffolds combined with stem cells and bioactive molecules could be a highly promising approach for cardiac *** of biomaterials can provide suitable microenvironment to the cells and can solve cell engraftment problems associated with cell transplantation *** stem cells(MSCs)are potential candidates in cardiac tissue engineering because of their multilineage differentiation potential and ease of *** of DNA methyl transferase inhibitor,such as zebularine,in combination with three-dimensional(3D)scaffold can promote efficient MSC differentiation into cardiac lineage,as epigenetic modifications play a fundamental role in determining cell fate and lineage specific gene *** To investigate the role of collagen scaffold and zebularine in the differentiation of rat bone marrow(BM)-MSCs and their subsequent in vivo *** MSCs were isolated from rat BM and characterized morphologically,immunophenotypically and by multilineage differentiation *** were seeded in collagen scaffold and treated with 3μmol/L zebularine in three different *** analysis was done and cardiac differentiation was analyzed at the gene and protein *** and untreated MSC-seeded scaffolds were transplanted in the rat myocardial infarction(MI)model and cardiac function was assessed by *** tracking was performed by DiI dye labeling,while regeneration and neovascularization were evaluated by histological and immunohistochemical analysis,*** MSCs were successfully isolated and seeded in collagen *** analysis revealed that zebularine was not cytotoxic in any of the treatment *** differentiation analysis

关键词： Mesenchymal stem cells Myocardial infarction Cardiac tissue engineering Demethylating agent Collagen scaffold Zebularine

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高质量的2μm高重频谐波锁模激光器

高质量的2μm高重频谐波锁模激光器

作者： waqas ahmad 电子科技大学

学位级别：硕士

2μm被动锁模光纤激光器因在光通信、医药学、中红外、激光雷达等领域的具有广泛的应用前景,已经成为了近些年来激光领域广大科研工作者的研究热点。本文分别从理论和实验上研究了2μm掺铥光纤激光器中的基频锁模和高重频谐波锁模孤子... 详细信息

2μm被动锁模光纤激光器因在光通信、医药学、中红外、激光雷达等领域的具有广泛的应用前景,已经成为了近些年来激光领域广大科研工作者的研究热点。本文分别从理论和实验上研究了2μm掺铥光纤激光器中的基频锁模和高重频谐波锁模孤子脉冲产生方法,相关研究工作可分为如下三个部分:（1）基于非线性薛定谔方程,我们建立了基于非线性偏振旋转的2微米被动锁模掺铥光纤激光器的数值模型。通过分步傅里叶法求解,我们研究了基频孤子随泵浦功率的演化情况,优化了掺铥光纤和普通单模光纤SMF28e的长度,结果表明当掺铥光纤长度5 m,普通单模光纤SMF28e为31 m时可获得脉冲能量最大基频孤子。（2）我们搭建了基于非线性偏振旋转的基频锁模掺铥光纤激光器,谐振腔总长度为36 m,腔内净色散为-2.9 ps。当泵浦功率为1.232 W时,可获得稳定的基频锁模孤子,其脉冲重复频率为5.8 MHz,与腔长相匹配,孤子光谱中心波长和半高全宽分别为1992.7 nm和2.02 nm,实验测得的脉冲宽度为2.2 ps,最大输出功率为10 mW,脉冲能量为1.72 nJ。为了提升基频孤子的脉冲重复频率并实现锁模自启动,我们采用了NPR锁模技术与真实可饱和吸收体相结合的混合锁模结构掺铥光纤激光器,获得了脉冲宽度为1.4 ps,重复频率22.81 MHz的自启动锁模脉冲。光谱的中心波长和半高全宽分别为1983.2 nm和3.42 nm。（3）在上述非线性偏转锁模腔中,引入一段长为20 m的色散补偿光纤,可将基频锁模光纤激光器转变为谐波锁模掺铥光纤激光器。色散补偿光纤用于改变腔内净色散降低孤子分裂阈值,并产生被动谐波锁模脉冲。稳定的基频锁模脉冲在泵浦功率750 mW率先产生,继续增加泵浦功率,开始高阶谐波锁模脉冲出现。在适合功率3.2 W泵浦下,可获得超模抑制比为19 dB的最大重复频率14.5 GHz的谐波锁模脉冲,这是目前在2微米波段锁模脉冲重复频率最高的光纤激光器。所获的脉冲宽度和光谱波长分别为1.3 ps和1982.3 nm。

关键词：孤子高重频谐波锁模色散管理