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STABIliTY CHARACTERISTICS OF LAMINAR BOUNDARY LAYERS OVER COMPliANT WALLS

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Acta Mechanica Sinica 1989年第2期5卷 109-117页

作者： li wanping Zhou Heng (Tianjin University) 1. Tianjin University Tianjin China

The stability characteristics of laminar boundary layers over compliant walls was studied by the linear *** the previous authors,the coupled motion of the fluid and solid was required to sat- isfy the continuity conditions of both the velocity and stress at the *** of calculations show that as the speed ratio or density ratio exceeds a certain threshold value,the two types of unstable waves will no longer be distinguishable,and the tangential component of the disturbance stress is no longer negligi- *** the neglect of it,as the previous authors did,is unjustified.

关键词： stability boundary layer compliant wall

Novel Soft Magnetic Co-Based Ternary Co-Er-B Bulk Metallic Glasses

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Acta Metallurgica Sinica(English Letters) 2024年第9期37卷 1633-1642页

作者： Jie Lu Yanhui li Shuang Ma wanping li Feng Bao Zhengwang Zhu Qiaoshi Zeng Haifeng Zhang Man Yao Wei Zhang Key Laboratory of Materials Modification By Laser Ionand Electron Beams(Ministry of Education)School of Materials Science and EngineeringDalian University of TechnologyDalian116024China School of Metallurgy Northeastern UniversityShenyang110819China Center for High Pressure Science and Technology Advanced Research(HPSTAR) PudongShanghai201203China

In this work,a series of Co-based ternary Co-Er-B bulk metallic glasses(BMGs)with excellent soft magnetic properties and high strength were developed,and the local atomic structure of a typical Co_(71.5)Er_(3.5)B_(25) metallic glass was studied through in situ high-energy synchrotron X-ray diffraction and ab initio molecular dynamics *** results reveal that the BMG samples can be obtained in a composition region of Co_(68.5-71.5)Er_(3.5-4)B_(25-27.5) by a conventional copper-mold casting *** Co-Er-B metallic glasses possess stronger atomic bond strengths and denser local atomic packing structure composed of a higher fraction of icosahedral-like clusters but fewer deformed body-centered cubic and crystal-like polyhedrons,and they exhibit slower atomic diffusion behaviors during solidification,as compared to Co-Y-B *** enhancement in structural stability and the retardation of atomic-ordered diffusion lead to the better glass-forming ability of the Co-Er-B *** smaller magnetic anisotropy energy in the Co-Er-B metallic glasses results in a lower coercivity of less than 1.3 A/*** Co-Er-B BMGs exhibit high-yield strength of 3560-3969 MPa along with distinct plasticity of around 0.50%.

关键词： Co-based bulk metallic glass Glass-forming ability Soft magnetic property Ab initio molecular dynamics simulation Local atomic structure

Metabolic and molecular analysis of nonuniform anthocyanin pigmentation in tomato fruit under high light

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Horticulture Research 2019年第1期6卷 1065-1085页

作者： Yanjie Zhang Yan li wanping li Zongli Hu Xiaohui Yu Yun Tu Min Zhang Jinyong Huang Guoping Chen Bioengineering College Chongqing University400030 ChongqingPeople’s Republic of China School of Agricultural Sciences Zhengzhou University450001 ZhengzhouPeople’s Republic of China

Pigment intensity and patterns are important factors that determine the nutritional and market values of tomato *** acropetal manner of light-dependent anthocyanin accumulation with the highest levels at the stem end of the fruit makes Pro35S:BrTT8 tomato plants an ideal system for investigating the effects of light intensity on anthocyanin *** transcript analyses indicate that anthocyanin pigmentation in Pro35S:BrTT8 plants under high light might be coordinately regulated by the exogenous protein BrTT8 and endogenous proteins SlAN2 and ***,yeast two-hybrid assays showed that BrTT8 could interact efficiently with SlAN2,SlMYBL2,and ***,the physical interaction between BrTT8 and SlAN2 was validated by *** overexpression of SlAN2 and BrTT8 activated significant anthocyanin biosynthesis in infiltrated tobacco *** addition,the ability of SlMYBL2 to suppress anthocyanin accumulation was also demonstrated in infiltrated tobacco ***,these results prove that tissue-specific assemblage of the heterogeneous MYB-bHLH-WD40 complex consisting of SlAN2,BrTT8 and SlAN11 triggers nonuniform anthocyanin accumulation in tomato fruit under high ***,it is proposed that a negative-feedback loop fulfilled by SlMYBL2 also participates in the regulation of anthocyanin production.

关键词： light anthocyanin analysis

The Effect of Near-Wall Vortices on Wall Shear Stress in Turbulent Boundary Layers

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Engineering（科研） 2010年第3期2卷 190-196页

作者： Shuangxi Guo wanping li 不详

The objective of the present study is to explore the relation between the near-wall vortices and the shear stress on the wall in two-dimensional channel flows. A direct numerical simulation of an incompressible two-dimensional turbulent channel flow is performed with spectral method and the results are used to examine the relation between wall shear stress and near-wall vortices. The two-point correlation results indicate that the wall shear stress is associated with the vortices near the wall and the maximum correlation-value location of the near-wall vortices is obtained. The analysis of the instantaneous diagrams of fluctuation velocity vectors provides a further expression for the above conclusions. The results of this research provide a useful supplement for the control of turbulent boundary layers.

关键词： Spectral Methods Two-Dimensional Turbulence Wall Shear Stress Two-Point Correlation

Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

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Acta Pharmaceutica Sinica B 2019年第2期9卷 203-219页

作者： Xu Wu Wei Hu Lan Lu Yueshui Zhao Yejiang Zhou Zhangang Xiao lin Zhang Hanyu Zhang Xiaobing li wanping li Shengpeng Wang Chi Hin Cho Jing Shen Mingxing li Laboratory of Molecular Pharmacology Department of Pharmacology School of Pharmacy Southwest Medical University Department of Gastroenterology Shenzhen Hospital Southern Medical University Sichuan Industrial Institute of Antibiotics Chengdu University Department of Gastrointestinal Surgery The Affiliated Hospital of Southwest Medical University Department of Anaesthesia and Intensive Care The Chinese University of Hong Kong State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical Sciences University of Macao

Tumor cells along with a small proportion of cancer stem cells exist in a stromal microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells and extracellular *** epidemiological and clinical studies strongly support that vitamin D supplementation is associated with reduced cancer risk and favorable prognosis. Experimental results suggest that vitamin D not only suppresses cancer cells, but also regulates tumor microenvironment to facilitate tumor repression. In this review, we have outlined the current knowledge on epidemiological studies and clinical trials of vitamin D. Notably, wesummarized and discussed the anticancer action of vitamin D in cancer cells, cancer stem cells and stroma cells in tumor microenvironment, providing a better understanding of the role of vitamin D in cancer. We presently re-propose vitamin D to be a novel and economical anticancer agent.

关键词： Vitamin D 1α,25-Dihydroxyvitamin D3 Tumor microenvironment Cancer stem cell Tumor-infiltrating lymphocyte Tumor-derived endothelial cell Cancer-associated fibroblast

Research on One-shot Drilling of CFRP/2A12 Laminated Structure

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纤维复合材料 2020年第3期37卷 9-13页

作者： li wanping WANG Kexin BAO Yongjie Dalian University of Technology School of Mechanical Engineering DalianLiaoning 116024 Dalian Maritime University Marine Engineering College DalianLiaoning 116026

CFRP/2A12 laminated structure due to the large difference in the properties of the material,very easy to produce defects when making holes,affecting the quality of the workpiece,and thus the connection performance of the two *** root cause of the poor quality of CFRP/2A12 laminated structure is the difference in material removal mechanism and the complexity of tool processing ***,this paper analyzes the effects of different process parameters on the pore-forming quality of the laminated material through experiments,reveals the change law of cutting force of the CFRP/2A12 laminated structure,and determines the optimal process *** results show:The axial force generated by the drill when it enters half of CFRP is the largest,which is much larger than the axial force generated when drilling 2A12 aluminum alloy plate,and the thickness of the laminated metal plate is great for *** hole formation sequence of the laminated structure has a significant effect on the cutting *** axial force when the laminated sequence is CFRP/2A12 is smaller than when the laminated sequence is 2A12/CFRP.

关键词： CFRP/2A12 laminated structure the pore-forming quality process parameters

Identification of host proteins that interact with African swine fever virus pE301R

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Engineering Microbiology 2024年第2期4卷 33-43页

作者： Menghan Shi Niu Zhou Mengchen Xiu Xiangzhi li Fen Shan Wu Chen wanping li Cheng-Ming Chiang Xiaodong Wu Youming Zhang Aiying li Jingjing Cao State Key Laboratory of Microbial Technology Microbial Technology InstituteShandong UniversityQingdao 266237China Guangzhou Zoo Guangzhou 510075China Wildlife Microbiology Laboratory Guangzhou Wildlife Research CenterGuangzhou 510075China Shandong Provincial Key Laboratory of Animal Cell and Developmental Biology School of Life SciencesAdvanced Medical Research InstituteShandong UniversityQingdaoChina Simmons Comprehensive Cancer Center University of Texas Southwestern Medical CenterDallasTX 75390USA Department of Biochemistry University of Texas Southwestern Medical CenterDallasTX 75390USA Department of Pharmacology University of Texas Southwestern Medical CenterDallasTX 75390USA China Animal Health and Epidemiology Center Qingdao 266032China

African swine fever virus(ASFV)infection poses enormous threats and challenges to the global pig industry;however,no effective vaccine is available against ASFV,attributing to the huge viral genome(approximately189 kb)and numerous encoding products(>150 genes)due to the limited understanding on the molecular mechanisms of viral *** the host-factor/viral-protein interaction network will reveal new targets for developing novel antiviral *** proteomic analysis,we identified 255 cellular proteins that interact with the ASFV-encoded pE301R protein when transiently expressed in HEK293T *** ontology(GO)annotation,Kyoto Encyclopedia of Genes and Genomes(KEGG)database enrichment,and protein-protein interaction(PPI)network analyses revealed that pE301R-interacting host proteins are potentially involved in various biological processes,including protein translation and folding,response to stimulation,and mitochondrial transmembrane *** interactions of two putative cellular proteins(apoptosis inducing factor mitochondria associated 1(AIFM1)and vimentin(VIM))with pE301R-apoptosis inducing factor have been verified by *** study revealed the inhibitory role of pE301R in interferon(IFN)induction that involves VIM sequestration by pE301R,identified interactions between ASFV pE301R and cellular proteins,and predicted the potential function of pE301R and its associated biological processes,providing valuable information to enhance our understanding of viral protein function,pathogenesis,and potential candidates for the prevention and control of ASFV infection.

关键词： African swine fever virus pE301R protein Protein-protein interaction network GO and KEGG analysis Interferon

粒子图像测速互相关中亚像素位移定位的改进方法

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计算机辅助设计与图形学学报 2011年第11期23卷 1896-1901页

作者：陈波李万平华中科技大学土木工程与力学学院武汉430074

通过分析粒子图像测速技术中互相关算法位移偏小的原因和误差变化规律,提出一种误差补偿修正的方法.首先计算出2个分别大于和小于真实亚像素位移的相关值平面,再对这2个相关值平面进行加权平均,通过分析误差变化规律得到加权系数;再由... 详细信息

通过分析粒子图像测速技术中互相关算法位移偏小的原因和误差变化规律,提出一种误差补偿修正的方法.首先计算出2个分别大于和小于真实亚像素位移的相关值平面,再对这2个相关值平面进行加权平均,通过分析误差变化规律得到加权系数;再由三点高斯插值计算加权平均后的相关值平面,得到较为精确的亚像素位移.在模拟均匀流场、Oseen涡流场以及标准射流场下进行实验的结果表明,该方法不但能提高均匀流场的计算精度,也能提高具有较大速度梯度流场的精度,具有较好的适用性.

关键词：粒子图像测速互相关修正算法偏移误差

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壁湍流相干结构尺度及边界层内的SL标度律

力学学报 2007年第1期39卷 23-36页

作者：赵伟李万平华中科技大学土木工程与力学学院武汉430074

利用高分辨率、高帧率PIV系统对湍流边界层中相干结构的多种空间尺度和边界层内SL标度律在不同尺度下的具体表达形式进行了实验研究．实验在两个动量损失厚度雷诺数(Reθ=628．5和Reθ=1032．9)下测量平板湍流边界层中缓冲层、对数区和... 详细信息

利用高分辨率、高帧率PIV系统对湍流边界层中相干结构的多种空间尺度和边界层内SL标度律在不同尺度下的具体表达形式进行了实验研究．实验在两个动量损失厚度雷诺数(Reθ=628．5和Reθ=1032．9)下测量平板湍流边界层中缓冲层、对数区和外区的二维瞬时速度场．应用小波分析以及传统的统计学方法,在垂直于平板和平行于平板的平面内考察平板湍流边界层中存在的相干结构的流向和展向尺度,并与已知的相干结构尺度实验结果进行了对比分析．利用在动量损失厚度雷诺数628．5下测得的数据,对多种脉动结构(脉动速度结构等)的空间关系及其标度律进行了研究．第2项工作直接利用湍流边界层空间速度分布,对多种流场尺度结构内部的She-Leveque(简称SL)标度律及自相似律进行了验证．结果表明,各单一流场尺度结构内部,流向脉动速度u’、法向脉动速度v’及脉动涡分量dv’／dx的统计结构量均存在明显的标度律,标度指数的形式与自相似律和SL标度律均非常吻合,只是常数随流场尺度的不同而不同,且呈现一定的规律性．但对于结构量的五阶矩随距离l的研究表明,自相似律和SL标度律成立的范围并不完全一致,同时标度律成立的范围大小与流场尺度有明显关系．

关键词：平板湍流边界层相干结构流向及展向尺度 PIV 标度律