检索结果-南通市图书馆

World Journal of Emergency Medicine 2023年第4期14卷 273-279页

作者： Jiafa Lu Xin Wang Linghao Chen Xuedong Sun Rui Li wanjing zhong Yajing Fu Le Yang Weixiang Liu Wei Han Emergency Department of Shenzhen University General Hospital Shenzhen 518055China Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhen 518055China School of Biomedical Engineering Health Science CenterShenzhen UniversityShenzhen 518060China Tianjin University Tianjin 300072China

BACKGROUND:Rapid on-site triage is critical after mass-casualty incidents(MCIs)and other mass injury *** aerial vehicles(UAVs)have been used in MCIs to search and rescue wounded individuals,but they mainly depend on the UAV operator’s *** used UAVs and artificial intelligence(AI)to provide a new technique for the triage of MCIs and more efficient solutions for emergency ***:This was a preliminary experimental *** developed an intelligent triage system based on two AI algorithms,namely OpenPose and *** were recruited to simulate the MCI scene and triage,combined with UAV and Fifth Generation(5G)Mobile Communication Technology real-time transmission technique,to achieve triage in the simulated MCI ***:Seven postures were designed and recognized to achieve brief but meaningful triage in *** volunteers participated in the MCI simulation *** results of simulation scenarios showed that the proposed method was feasible in tasks of triage for ***:The proposed technique may provide an alternative technique for the triage of MCIs and is an innovative method in emergency rescue.

关键词： Mass-casualty incidents Emergency medical service Unmanned aerial vehicle Fifth Generation Mobile Communication Technology Artificial intelligence

Hybrid liposome-erythrocyte drug delivery system for tumor therapy with enhanced targeting and blood circulation

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2023年第1期10卷 1021-1032页

作者： Kehui Zhu Yingcan Xu Rui zhong wanjing Li Hong Wang Yee Shan Wong Subramanian Venkatraman Jiaxin Liu Ye Cao Institute of Blood Transfusion Chinese Academy of Medical Sciences&Peking Union Medical CollegeChengduChina Biomedical Engineering School of EngineeringTemasek PolytechnicSingaporeSingapore School of Materials Science and Engineering National University of SingaporeSingaporeSingapore

Liposome,a widely used drug delivery system(DDS),still shows several disadvantages such as dominant clearance by liver and poor target organ *** overcome the drawbacks of liposomes,we developed a novel red blood cell(RBC)-liposome combined DDS to modulate the tumor accumulation and extend the blood circulation life of the existing liposomal ***,RBCs,an ideal natural carrier DDS,were utilized to carry liposomes and avoid them undergo the fast clearance in the *** this study,liposomes could either absorbed onto RBCs’surface or fuse with RBCs’membrane by merely altering the interaction time at 37℃,while the interaction between liposome and RBCs would not affect RBCs’*** the in vivo antitumor therapeutic efficacy study,1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)liposomes attached onto RBCs’surfaces exhibited lung targeting effect(via RBC-hitchhiking approach)and reduced clearance in the liver,while DPPC liposomes fused with RBCs had prolong blood circulation up to 48 h and no enrichment in any ***,20 mol%of DPPC liposomes were replaced with pH-sensitive phospholipid 1,2-dioleoyl-Sn-glycero-3-phosphoethanolamine(DOPE)as it could respond to the low pH tumor microenvironment and then accumulate in the *** DOPE attached/fusion RBCs showed partial enrichment in lung and about 5-8%tumor accumulation,which were significantly higher than(about 0.7%)the conventional liposomal ***,RBC-liposome composite DDS is able to improve the liposomal tumor accumulation and blood circulation and shows the clinical application promises of using autologous RBCs for antitumor therapy.

关键词： liposomes erythrocyte RBC-hitchhiking blood circulation target delivery

Defects and asymmetries in the visual pathway of non-human primates with natural strabismus and amblyopia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2023年第1期44卷 153-168页

作者： Feng Liu zhong-Hao Wang wanjing Huang Ying Xu Xuan Sang Ruifeng Liu Zhou-Yue Li Ya-Lan Bi Lei Tang Jing-Yi Peng Jia-Ru Wei Zhi-Chao Miao Jian-Hua Yan Sheng Liu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-Sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhouGuangdong 510060China Guangdong-Hongkong-Macao Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong 510632China European Molecular Biology Laboratory European Bioinformatics Institute(EMBL-EBI)Wellcome Genome CampusCambridge CB101SDUK Translational Research Institute of Brain and Brain-Like Intelligence and Department of Anesthesiology Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200081China Guangdong Province Key Laboratory of Brain Function and Disease GuangzhouGuangdong 510080China

Strabismus and amblyopia are common ophthalmologic developmental diseases caused by abnormal visual experiences. However, the underlying pathogenesis and visual defects are still not fully understood. Most studies have used experimental interference to establish diseaseassociated animal models, while ignoring the natural pathophysiological mechanisms. This study was designed to investigate whether natural strabismus and amblyopia are associated with abnormal neurological defects. We screened one natural strabismic monkey(Macaca fascicularis) and one natural amblyopic monkey from hundreds of monkeys, and retrospectively analyzed one human strabismus case. Neuroimaging, behavioral,neurophysiological, neurostructural, and genovariation features were systematically evaluated using magnetic resonance imaging(MRI), behavioral tasks, flash visual evoked potentials(FVEP),electroretinogram(ERG), optical coherence tomography(OCT), and whole-genome sequencing(WGS), respectively. Results showed that the strabismic patient and natural strabismic and amblyopic monkeys exhibited similar abnormal asymmetries in brain structure, i.e., ipsilateral impaired right hemisphere. Visual behavior, visual function, retinal structure, and fundus of the monkeys were impaired. Aberrant asymmetry in binocular visual function and structure between the strabismic and amblyopic monkeys was closely related, with greater impairment of the left visual *** similar known mutant genes for strabismus and amblyopia were also identified. In conclusion,natural strabismus and amblyopia are accompanied by abnormal asymmetries of the visual system,especially visual neurophysiological and neurostructural defects. Our results suggest that future therapeutic and mechanistic studies should consider defects and asymmetries throughout the entire visual system.

关键词： Non-human primates Natural disease models Strabismic patients Strabismus Amblyopia

Stable error-free single channel 160-Gb/s OTDM 100-km transmission via high-precision dispersion management

在线全文

学校读者我要写书评

暂无评论

Chinese Optics Letters 2010年第8期8卷 741-744页

作者：贾楠李唐军钟康平王目光陈明卢丹彭万敬池剑锋 Key Lab of All Optical Networks and Advanced Communication Network of EMC Beijing Jiaotong University Institute of Lightwave Technology Beijing Jiaotong University

A single channel with a 160-Gb/s optical time-division-multiplexing （OTDM） transmission over 100 km is fabricated. With the help of 500-GHz optical sampling oscilloscopes, the fiber length is adjusted to the order of 10 m, which corresponds to the accuracy of 0.4 ps for the dispersion compensation. The dispersion map is optimized for the 100-km transmission link. A completely error-free transmission with the power penalty of 3.6 dB is achieved for 2 h without using forward error correction.

关键词： OTDM link Stable error-free single channel 160-Gb/s OTDM 100-km transmission via high-precision dispersion management DCF free than high

面向多类型交通冲突的道路条件及交通状况影响评估

在线全文

学校读者我要写书评

暂无评论

交通信息与安全 2023年第6期41卷 114-123页

作者：钟昊马万经王玲同济大学道路与交通工程教育部重点实验室上海201804

交通冲突为交通事故发生前的潜在状态。探究静态路段属性和动态交通流特性等宏观特征对于交通冲突的影响至关重要,但现有研究主要关注2辆车之间的危险状态,对于涉及多个交通主体的冲突缺乏重视。为有效提取包括单一冲突和连锁冲突在内... 详细信息

交通冲突为交通事故发生前的潜在状态。探究静态路段属性和动态交通流特性等宏观特征对于交通冲突的影响至关重要,但现有研究主要关注2辆车之间的危险状态,对于涉及多个交通主体的冲突缺乏重视。为有效提取包括单一冲突和连锁冲突在内的多类型交通冲突,基于无人机采集的车辆轨迹数据首先识别车辆对之间的单一冲突,另通过关联匹配辨识连锁冲突,并基于聚类将连锁冲突划分为纵向风险下降模式、纵向风险增加模式和横纵向高风险持续模式。构建巢式Logit模型探究宏观交通属性及路段条件对多类型单一冲突和连锁冲突的影响,结果表明合流区和基本路段为单一冲突的高发区域,而分流区和交织区为连锁冲突高发区域,尤其会导致横纵向高风险持续模式的发生,但车道数的增加有助于减少严重连锁冲突的发生。此外,主线交通密度增大,连锁冲突发生概率增加;匝道与主线的流量比增大时,连锁冲突更易发生,其中纵向风险增加模式对交通流量最为敏感。将各类型冲突发生的交通流条件与宏观基本图结合分析,表明各类型交通冲突的发生次数存在峰值,且路段上交通冲突发生最多的临界密度要高于同一路段宏观基本图的临界密度。研究结论有助于理解多车连锁冲突发生的宏观原因,有效阻断其演化为连锁碰撞。

关键词：交通安全多类型交通冲突冲突影响因素巢式Logit模型路段属性交通流特征

含醛基聚合物的“活性”/可控自由基聚合研究进展

在线全文

学校读者我要写书评

暂无评论

材料导报 2010年第15期24卷 64-68页

作者：肖乃玉翟万京钟乐白卫东赵晓娟仲恺农业工程学院轻工食品学院广州510225

主要综述了利用原子转移自由基聚合(ATRP)和"活性"/可控RAFT自由基聚合合成结构明确的、分子量大小和分布可控的含醛基聚合物,以及所得聚合物与蛋白质、酶、药物等生物分子通过Schiff碱连接形成的生物分子-聚合物缀合物的最新研究;同时... 详细信息

主要综述了利用原子转移自由基聚合(ATRP)和"活性"/可控RAFT自由基聚合合成结构明确的、分子量大小和分布可控的含醛基聚合物,以及所得聚合物与蛋白质、酶、药物等生物分子通过Schiff碱连接形成的生物分子-聚合物缀合物的最新研究;同时也简单介绍了由"活性"/可控自由基聚合所得的两亲性醛基聚合物纳米胶束的形成,并展望了含醛基聚合物今后可能的发展方向。

关键词：含醛基聚合物原子转移自由基聚合 RAFT聚合生物分子-聚合物缀合物

丁香/香茅精油复合涂膜对百香果采后保鲜的研究

在线全文

学校读者我要写书评

暂无评论

食品与发酵工业 2023年第4期49卷 59-67页

作者：李结瑶罗文翰肖更生翟万京仲芸芸张雪琴徐意芳蓝碧锋肖乃玉仲恺农业工程学院包装工程系广东广州510225 广东省岭南特色食品科学与技术重点实验室广东广州510225 广东省普通高校中央厨房岭南特色食品绿色制造工程技术开发中心广东广州510225 广州辐锐高能技术有限公司广东广州511458

该文主要探究植物源保鲜剂丁香/香茅精油的添加,对壳聚糖(chitosan,CTS)/乙烯共聚物(ethylene copolymer,ECP)乳液复合膜包装性能的影响以及在常温贮藏过程中对百香果的保鲜效果。该研究分别用0.25%(体积分数)的丁香精油、香茅精油以及... 详细信息

该文主要探究植物源保鲜剂丁香/香茅精油的添加,对壳聚糖(chitosan,CTS)/乙烯共聚物(ethylene copolymer,ECP)乳液复合膜包装性能的影响以及在常温贮藏过程中对百香果的保鲜效果。该研究分别用0.25%(体积分数)的丁香精油、香茅精油以及两者按不同比例混合精油作为天然抗菌剂与CTS/ECP乳状液复配,同时以CTS/ECP乳状液及空白组为对照,测定其对百香果失重率、呼吸强度、维生素C含量、可溶性固形物含量、可滴定酸含量等的影响,并对货架期内商品外观变化的情况进行评价。为进一步探究精油复合薄膜的保鲜过程,对保鲜效果最优的复合薄膜进行力学性能、透气透湿性能、扫描电镜形貌分析。结果表明,丁香/香茅精油的添加可有效改善薄膜的力学性能、透气透湿性能;保鲜实验中,不同组分的精油与CTS/ECP复合涂膜处理均能有效减少百香果果实水分、维生素C等成分的损失,降低失重率,延缓百香果的腐烂,延长货架期2~3 d。综合各种理化指标的评价,当丁香与香茅精油体积比为3∶2时,保鲜效果最佳。

关键词：丁香香茅复合涂膜百香果保鲜

专本结合校校协同包装工程人才培养模式的探索

在线全文

学校读者我要写书评

暂无评论

科教文汇 2014年第18期 68-69页

作者：肖乃玉李彭丘苑新钟乐翟万京仲恺农业工程学院轻工食品学院广东广州510225 中山火炬职业技术学院广东中山528436

本文通过对包装行业以及人才需求现状的分析,探讨开展专本结合培养模式的必要性,提出专本结合人才培养模式的具体实施方案和保障制度。本文的探索为我国高校人才培养模式的改革提供新思路。

关键词：专本结合协同培养包装工程

在线全文

学校读者我要写书评

暂无评论

5种藁本属近缘药用植物花粉的形态特征

东北林业大学学报 2024年第11期52卷 56-63页

作者：徐皖菁张超吴宇陶珊毛常清钟明志徐正君彭芳四川农业大学水稻研究所成都611130 四川省农业科学院经济作物研究所

为了探究5种藁本属近缘药用植物(川芎、西芎、辽藁本、藁本、丽江藁本)花粉的亲缘关系,利用扫描电子显微镜对5种藁本属近缘种花粉的形态大小、表面纹饰等进行观测,并统计其形态学参数。同时,对5种藁本属近缘药用植物的花粉性状进行相关... 详细信息

为了探究5种藁本属近缘药用植物(川芎、西芎、辽藁本、藁本、丽江藁本)花粉的亲缘关系,利用扫描电子显微镜对5种藁本属近缘种花粉的形态大小、表面纹饰等进行观测,并统计其形态学参数。同时,对5种藁本属近缘药用植物的花粉性状进行相关性分析、主成分分析、系统聚类分析。结果表明:5种藁本属花粉的形状相似,均为超长球形,有3个萌发孔沟,而5种藁本属花粉在极面观、赤道面观、外壁纹饰、萌发孔沟的形态上均存在差异。5种藁本属花粉的极轴长为26.34~41.20μm、赤道轴长为10.40~15.83μm、极赤比为2.36~2.76、外壁弧形宽度为5.36~9.24μm、外壁弧形高度为3.31~4.47μm、极面弧形弯曲率为0.47~0.61、极面直径为8.22~14.13μm、赤道面直径为18.52~28.51μm,其中川芎花粉极面弧形弯曲率指标为中度变异。在比较花粉形态时发现,川芎、西芎畸形比例较高,多数花粉出现明显皱缩、扭曲。由主成分分析可知,影响藁本属近缘种花粉分类的主要形态指标为赤道轴长、极赤比、极面弧形弯曲率;对5种藁本属花粉进行聚类分析发现,当欧氏距离为20时,共分为两种类群,其中川芎与辽藁本更接近,西芎与藁本更接近。

关键词：藁本属花粉形态孢粉学

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

嵌入式单点自适应信号控制系统软件设计

交通与计算机 2008年第5期26卷 127-130页

作者：姚佼时柏营马万经钟章建同济大学上海200092 长沙理工大学长沙410076

将嵌入式技术应用于单点信号控制系统中,不仅可以实现信号控制机对配时方案的自适应优化,还可以通过远程控制中心对路口控制状态进行监控,为后续将其嵌入到先进的城市交通控制系统中奠定坚实的基础。文中在分析嵌入式单点自适应控制系... 详细信息

将嵌入式技术应用于单点信号控制系统中,不仅可以实现信号控制机对配时方案的自适应优化,还可以通过远程控制中心对路口控制状态进行监控,为后续将其嵌入到先进的城市交通控制系统中奠定坚实的基础。文中在分析嵌入式单点自适应控制系统总体构架的基础上,基于嵌入式Linux开发平台,着重于对嵌入式控制单元中自适应控制优化算法的流程设计,以及控制中心监控终端软件的实现,并对系统的后续开发升级进行了展望。

关键词：嵌入式单点自适应信号控制机监控终端