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FY-3 Meteorological Satellites and the Applications

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空间科学学报 2014年第5期34卷 703-709页

作者： tang yunqiu zhang jiashen wang jingsong National Satellite Meteorological Center/National Center for Space Weather China Meteorological Administration

FY-3 is the second generation polar-orbiting meteorological satellite of China. The first satellite named FY-3A of this series was launched on 27 May 2008. The first operational satellite named FY-3C of this series was launched on 23 September, 2013. The new generation satellites are to provide three-dimensional, quantitative, multi-spectral global remote sensing data under all weather conditions, which will greatly help the operational numerical weather prediction, global climate change research, climate diagnostics and prediction, and natural disaster monitoring. They will also provide help for many other fields such as agriculture, forestry, oceanography and hydrology. With the above-mentioned capability, the FY-3 satellites can make valuable contributions to improving weather forecasts, global natural-disaster and environmental monitoring.

关键词： FY-3 satellites Polar-orbiting satellite Remote sense

Observations from Fengyun Satellites

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空间科学学报 2016年第5期36卷 762-770页

作者： tang yunqiu LI Yingying zhang jiashen wang jingsong National Satellite Meteorological Center/National Center for Space Weather China Meteorological Administration Department of Integrated Observations China Meteorological Administration

Fengyun(FY) Satellite has a polar-orbiting series and a geostationary *** to now,7 polar-orbiting(FY-1A/B/C/D and FY-3A/B/C) and 7 geostationary(FY-2A/B/C/D/E/F/G)satellites were *** data has been being intensively applied not only to meteorological monitoring and prediction but also to many other fields regarding ecology,environment,disaster and so on.

关键词：卫星数据观测值监测预报气象灾害

A digital open-loop Doppler processing prototype for deep-space navigation

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Science China(Physics,Mechanics & Astronomy) 2009年第12期52卷 1849-1857页

作者： JIAN NianChuan SHANG Kun zhang SuJun wang MingYuan SHI Xian PING jingsong YAN JianGuo tang GeShi LIU JunZe QIU Shi FUNG Lai-Wo zhang Hua wang Zhen GOU Wei Shanghai Astronomical Observatory of Chinese Academy of Sciences Shanghai 200030China Graduate University of Chinese Academy of Sciences Beijing 100049China Beijing Aerospace Command and Control Center Beijing 100094China Urumqi Astronomical Station of National Astronomical Observatories CASUrumqi 830011China State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhan 430070China

A prototype based on digital radio technology with associated open-loop Doppler signal processing techniques has been developed to measure a spacecraft's line-of-sight velocity. The prototype was tested in China's Chang'E-1 lunar mission relying on S-band telemetry signals transmitted by the sat-ellite,with results showing that the residuals had a RMS value of ～3 mm/s (1σ ) using 1-sec integration,which is consistent with the Chinese conventional USB (Unified S-Band) tracking system. Such preci-sion is mainly limited by the short-term stability of the atomic (e.g. rubidium) clock at the uplink ground station. It can also be improved with proper calibration to remove some effects of the transmission media (such as solar plasma,troposphere and ionosphere),and a longer integration time (e.g. down to 0.56 mm/s at 34 seconds) allowed by the spacecraft dynamics. The tracking accuracy can also be in-creased with differential methods that may effectively remove most of the long-term drifts and some of the short-term uncertainties of the uplink atomic clock,thereby further reducing the residuals to the 1 mm/s level. Our experimental tracking data have been used in orbit determination for Chang'E-1,while other applications (such as the upcoming YH-1 Mars orbiter) based on open-loop Doppler tracking will be initiated in the future. Successful application of the prototype to the Chang'E-1 mission in 2008 is believed to have great significance for China's future deep space exploration.

关键词： open-loop Doppler differential Doppler deep space navigation Chang’E-1

The inhibitory effect of triterpenoids of Ganoderma lucidum on prostate cancer and the mechanism of inhibition

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The inhibitory effect of triterpenoids of Ganoderma lucidum ...

Consensus on the application of negative pressure wound therapy of diabetic foot wounds

中国菌物学会2015年学术年会

作者： zhang jingsong zhang Hui JIA Wei wang Wenhai Yang Yan tang Qingjiu tang Chuanhong Liu Yanfang Zhou Shuai FENG Na Hua Fan Institute of Edible Fungi Shanghai Academy of Agricultural Sciences

The fruiting body of Ganoderma lucidum（GL） has been used as a folk medicine in the oriental country for a long time. For the past few years, the triterpenes extract from GL has been identified as an important active ingredient which possessing anti-cancer activities and many other pharmacological activities. More than 160 kinds of triterpenes had been separated form GL. However, the study and application of triterpenes were limited by the low content and hard obtainment. In order to found some methods to solve these problems, we make some efforts in our study. Firstly, supercritical CO2 extraction（SFE-CO2）was applied for extract triterpenes from the fruiting body of GL, and then anti-prostate cancer activity was used as an tracking means for separation and purification of triterpenes from GL. After that, we also had studied the mechanism of anti-prostate cancer activity of active ingredients. Single parameter and orthogonal tests were used to determine the optimal conditions for extracting triterpenes from the fruiting body of GL using SFE-CO2. Highest extraction rates were achieved when the fruiting bodies of GL were pulverized to 10 mesh particle size, an entrainer（ethanol） concentration of 95%, 35 Mpa extraction pressure, 40 ℃, 2.5 h extraction time, a carbon dioxide flow rate of 35 g/min, and an entrainer: The fruiting body of GL weight ratio of 6:1（mL :g）. Under these conditions, the yield of crude extract was 2.42 g and the triterpene content of the crude extract was 40.5%, giving a triterpene yield of 0.98%. Crude extract and triterpene yields obtained using SFE-CO2 were lower compared with levels obtained using ethanol extraction but the former extracts contained a higher percentage and a greater number of triterpenes. The comparison on bioactivities of two sorts of extracts from the fruit body of GL obtained from SFE-CO2 and ethanol extraction separately was investigated antitumor effect in vitro. The inhibition rate of supercritical CO2 fluid extracts（SFE-

关键词： Ganoderma lucidum Supercritical CO2 extraction Separation and purification Anti-prostated cancer Androgen

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Burns & Trauma 2021年第1期9卷 421-432页

作者： Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu tang Aiping wang Guangyi wang Jiangning wang Xin wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi zhang Shichu Xiao Zhaofan Xia Burn Institute of PLA Department of BurnsThe First Affiliated Hospital of Naval Medical UniversityNo.168 Changhai RoadYangpu DistrictShanghai200433China Fujian Burn Institute Fujian Medical University Union HospitalNo.29 Xinquan RoadGulou DistrictFuzhou350001China Department of Burns&Wound Care Center Second Affiliated Hospital of Zhejiang UniversityCollege of MedicineNo.88 Jiefang RoadShangcheng DistrictHangzhou310009China No.3 Department of Burns and Plastic Surgery and Wound Healing Center The Fourth Medical Center of Chinese PLA General HospitalNo 51 Fucheng RoadHaidian DistrictBeijing100048China Foot and Ankle Surgery Department Guangzhou Zhenggu Orthopedic HospitalNo.449 Dongfeng Middle RoadYuexiu DistrictGuangzhou510031China Department of Burns and Cutaneous Surgery The First Affiliated Hospital of Air Force Medical UniversityNo.127 West Changle RoadXincheng DistrictXi’an710032China Wound Healing Department PLA Strategic Support Force Characteristic Medical CenterNo.9 Anxiang North LaneChaoyang DistrictBeijing100101China Department of Peripheral Vascular Beijing University of Chinese MedicineDongzhimen HospitalHai Yun Cang on the 5thDongcheng DistrictBeijing100700China Department of Orthopedics Zhejiang University School of MedicineSir Run Run Shaw HospitalNo.3 East Qinchun RoadShangcheng DistrictHangzhou310016China Department of Burns The Fifth Hospital of HarbinNo.27 Jiankang RoadXiangfang District150030HarbinChina Institute of Burn Research State Key Laboratory of TraumaBurn and Combined InjurySouthwest HospitalThird Military Medical UniversityGaotanyan Street no.29Shapingba DistrictChongqing400038China Department of Burn Shanghai Jiaotong UniversitySchool of Medicine Affiliated Ruijin HospitalNo.197 Ruijin Road(No.2)Huangpu DistrictShanghai200025China Department of Burn Surgery the Third People’s Hospital of WuxiNo.585 North Xingyuan RoadWuxi214043China Innovation Center for Wound Rpair Diabetic Foot Care CenterDepartment of Endoc

Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been *** foot has become one of the main health-related killers due to its high disability and mortality *** pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its ***,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment *** 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound *** on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic *** consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot.

关键词： Vacuum sealing drainage Vacuum-assisted closure Vacuum-assisted therapy Negative pressure wound therapy Topical negative pressure therapy Suction wound closure therapy Diabetic foot Diabetic ulcer Diabetic wound

Research progress of polysaccharides from Medicinal Fungi

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Research progress of polysaccharides from Medicinal Fungi

pH对灵芝液态发酵代谢物及抗氧化活性的影响

中国菌物学会2018年学术年会

作者： jingsong zhang Hua Fan Yan Yang Qingjiu tang Yanfang Liu Wei Jia Wenhan wang Chuanhong tang Di Wu Shuai Zhou Jie Feng Haining Zhuang National Research Center of Edible Fungi Biotechnology and Engineering

The medicinal Fungi had played an important role in traditional Chinese medicine and have been used to treat different diseases in China for a long time. In recent years, many studies have been undertaken worldwide,and have ascertained that components of the mushroom possessed various therapeutic functions including immunomodulating activity, antitumor, antidiabetes and hepatoprotective ability and so on. It was found that many bioactivities of medicinal Fungi are relative with the polysaccharide. The study was focused on chemical structure and bioactivity of polysaccharides from 7 different important medicinal fungi, Ganoderma lucidum,Ganoderma sinense, Hericium erinaceus, Pleurotus eryngii,Coprinus comatus,Phellinus igniarius,Tremella aurantialba,Flammulina velutiper. 22 homogeneous polysaccharides were purified from hot water and alkali extracts of the fruiting body or spores using a series of chromatographic steps. Their chemical structures were elucidated by sugar analysis, methylation analysis and NMR. These polysaccharides was classified toβ-glucan,α-glucan, Fucogalactan, Fucoglucogalactan, Galactoglucan, acidic polysaccharides. Conformation of a 1,3/1,6-glucan from G. lucidum was studied by HPSEC-MALLS-RI system and Laser light scattering method;it was found conformation of the glucan is triple helix in solution. The bioactivity of these polysaccharides were found to induce macrophage activation and B or T cell activation, stimulate the proliferation of lymphocytes,stimulate the secretion of cytokines and immunoglobulins of lymphocytes and inhibit the Sarcoma S180 tumor growth. A sulfated polysaccharide deritive of Ganoderma lucidum, GLPss58, was found to possess the anti-inflammatory properties by inhibited the L-selectin – s Tyr/sLeX binding of lymphocytes. Our research results indicated that the structure and bioactivity of polysaccharides from medicinal fungi was diversity, it is difficult to obtain the clear structure-functional relationship of polysacc

关键词： Medicinal mushroom glucan bioactivity

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菌物学报 2023年第2期42卷 570-583页

作者：唐晨旻张劲松刘艳芳唐业王鹏冯杰上海海洋大学食品学院上海201306 上海市农业科学院食用菌研究所、国家食用菌工程技术研究中心、农业农村部南方食用菌资源利用重点实验室上海201403 江苏神华药业有限公司、江苏省药用真菌生物工程技术研究中心江苏淮安211600

已有研究报道灵芝栽培生长的最适pH在中性偏酸环境,在碱性范围的生长及代谢情况鲜见报道。本研究主要探究广泛pH对灵芝液态发酵代谢物及其抗氧化活性的影响。采用摇瓶液态培养后分析代谢物中灵芝三萜、胞内外多糖、菌丝体蛋白及抗氧化... 详细信息

已有研究报道灵芝栽培生长的最适pH在中性偏酸环境,在碱性范围的生长及代谢情况鲜见报道。本研究主要探究广泛pH对灵芝液态发酵代谢物及其抗氧化活性的影响。采用摇瓶液态培养后分析代谢物中灵芝三萜、胞内外多糖、菌丝体蛋白及抗氧化活性等指标,系统比较灵芝菌丝体在pH值2–11的生长和代谢情况。研究结果表明,灵芝菌丝体生长、合成灵芝三萜、胞内多糖、30E胞外多糖、菌丝体蛋白和菌丝体水解氨基酸的最适pH值分别为10、3、2、7、2和2。对应结果分别为17.13g/L、33.86mg/g、72.73mg/g、7.86g/L、71.42mg/g和107.10mg/g。比对照分别提高28.5%、77.3%、22.4%、96.5%、97.1%和70.8%。胞内多糖组分1和组分2最高分子量均在初始pH4,分别为1.016×10^(8)g/mol和9.280×10^(4)g/mol,胞外多糖组分1最高分子量在初始pH10,为4.946×10^(6)g/mol;对菌丝体的总抗氧化能力、1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基清除能力、羟自由基清除能力分析结果表明最佳的初始pH分别为3、7、9。本研究为液态发酵方式下灵芝生长及其代谢物定向调控发酵的工艺优化提供参考依据,同时发现灵芝菌丝体中优质蛋白及抗氧化活性可在功能性食品和化妆品领域推广应用。

关键词：灵芝 pH值液态发酵代谢物菌丝体蛋白抗氧化

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分光光度法测定灵芝三萜含量的干扰因素探讨

菌物学报 2022年第10期41卷 1716-1725页

作者：程池露汪旵王金艳唐传红张劲松冯娜唐庆九上海市农业科学院食用菌研究所农业部南方食用菌资源利用重点实验室国家食用菌工程技术研究中心国家食用菌加工技术研发分中心上海市农业遗传育种重点开放实验室上海201403 上海海洋大学食品学院上海201306 华东理工大学化工学院制药工程与过程化学教育部工程研究中心上海市新药设计重点实验室上海200237

根据药典方法,以齐墩果酸为对照品,对灵芝中含有的三萜、甾醇和脂肪酸3种类型化合物进行分光光度法测定,并对影响三萜含量测定的因素进行分析。结果表明灵芝中的甾醇和脂肪酸类化合物会干扰所有的测定结果,尤其影响灵芝孢子中三萜含量... 详细信息

根据药典方法,以齐墩果酸为对照品,对灵芝中含有的三萜、甾醇和脂肪酸3种类型化合物进行分光光度法测定,并对影响三萜含量测定的因素进行分析。结果表明灵芝中的甾醇和脂肪酸类化合物会干扰所有的测定结果,尤其影响灵芝孢子中三萜含量的测定。灵芝子实体中三萜化合物的结构特征,造成了其测定值远远低于真实值。因此,分光光度法不适用于测定灵芝子实体、菌丝体和孢子及其相关产品中的三萜含量。

关键词：分光光度法三萜甾醇脂肪酸

HPLC-ELSD测定灵芝孢子粉及产品中游离脂肪酸的含量

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菌物学报 2023年第9期42卷 1993-2000页

作者：孙泽东张劲松周靖王晨光王金艳唐庆九上海市农业科学院食用菌研究所农业农村部南方食用菌资源利用重点实验室国家食用菌工程技术研究中心上海市农业遗传育种重点实验室上海201403 上海海洋大学食品学院上海201306 上海百信生物科技有限公司上海201403

为准确测定灵芝孢子粉产品的酸价,阐明影响酸价的关键因素,本试验建立了高效液相色谱-蒸发光散射检测器(high performance liquid chromatography-evaporative light scattering detector,HPLC-ELSD)分析方法测定孢子油中游离脂肪酸的... 详细信息

为准确测定灵芝孢子粉产品的酸价,阐明影响酸价的关键因素,本试验建立了高效液相色谱-蒸发光散射检测器(high performance liquid chromatography-evaporative light scattering detector,HPLC-ELSD)分析方法测定孢子油中游离脂肪酸的含量。通过优化色谱条件,建立了亚油酸、棕榈酸和油酸的HPLC的定量测定方法。该方法精密度、重复性和稳定性好,可用于灵芝孢子粉、孢子油及其相关产品中亚油酸、棕榈酸和油酸成分的定量测定。与国标化学法测定的结果比较,两种方法的匹配度较好,HPLC-ELSD法灵敏度高,可以测定不同脂肪酸的含量。通过比较分析发现,贮存时间对破壁灵芝孢子粉脂肪酸影响最大,同时产地和采收时间也影响酸价的大小。对8种不同品牌市售灵芝孢子油产品的脂肪酸含量测定,发现脂肪酸含量相差较大,其中含量最高的为(99.81±10.21)mg/g,最低的为(1.90±0.12)mg/g。因此新建立的HPLC-ELSD法可精确定量灵芝孢子粉中游离脂肪酸,为市场上灵芝孢子类产品的质量控制提供科学依据。

关键词：灵芝孢子粉高效液相色谱-蒸发光散射检测器(HPLC-ELSD) 脂肪酸酸价