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Efficacy of Ciji Hua'ai Baosheng formula on the expressions of vascular endothelial growth factor,kinase insert domain-containing receptor and basic fibroblast growth factor in mouse models of H22 hepatocellular carcinoma

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Journal of Traditional Chinese Medicine 2017年第1期37卷 88-95页

作者： Zhao Xinyue Xi Shengyan wang yanhui Xu Yangxinzi Pollock Galia Su Yu Cheng Yao Loy Guanjie Liu Pei Department of Traditional Chinese Medicine Medical College of Xiamen University Cancer Research Center of Xiamen University Xiamen 361102China Department of Internal Medicine John Buhler Research CentreUniversity of ManitobaWinnipeg FI3E 3P4Canada

OBJECTIVE: To investigate the efficacy of Ciji Hua'ai Baosheng formula(CHBF) on microvessel density(MVD) and vascular endothelial growth factor(VEGF), kinase insert domain-containing receptor(KDR) and basic fibroblast growth factor(b FGF) expression in serum and tumor tissue of mice receiving chemotherapy for the treatment of H22 hepatocellular ***: Sixty Kunming mice were injected subcutaneously with H22 hepatoma carcinoma cell suspensions into the right anterior armpit. Seven days later, all transplanted tumor were formed and the mice were intraperitoneally injected 200 mg/kg cytoxan(CTX) to establish the models of tumor-bearing mouse chemotherapy, then they were randomly divided into model group, continuing CTX chemotherapy group(CTX group), and three CHBF(117, 58.5 and 29.25 g/kg) groups. After ten days of treatments, histology was observed, contents of VEGF, KDR and b FGF in serum and tumor tissue were measured by enzyme-linked immunosorbent assay(ELISA), VEGF and b FGF protein expression and MVD tagged by CD34 were detected by ***: MVD in CHBF(117, 58.5 g/kg) and CTX groups was significantly lower than that in model group(P < 0.01); expressions of VEGF, KDR and b FGF in serum and tumor tissue in CHBF(117 g/kg)group were less than those in model group(P <0.05; P < 0.01); the expressions of MVD, VEGF and b FGF in tumor tissue of CHBF(117 g/kg) groupwere also less than those in CTX group(P < 0.05;P < 0.01).CONCLUSION: CHBF can effectively reduce the expression of VEGF, KDR and b FGF in serum and tumor tissue, and decrease MVD and delay tumor progression.

关键词： Drug therapy Angiogenesis inhibitors Vascular endothelial growth factors Receptors vascular endothelial growth factor Basic fibroblast growth factor 2 Ciji Hua’ai Baosheng formula

Changing Forestry Policy by Integrating Water Aspects into Forest/Vegetation Restoration in Dryland Areas in China

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Bulletin of the Chinese Academy of Sciences 2012年第1期26卷 59-67页

作者： wang yanhui Mike Bonell Karl-Heinz Feger YU Pengtao XIONG Wei XU Lihong Research Institute of Forest Ecology Environment and Protection Chinese Academy of Forestry Beijing 100091 China The UNESCO IHP-HELP Centre University of Dundee Dundee DD1 4HN UK Faculty of Forestry Geo- and Hydrosciences Dresden Water Center Dresden University of Technology 01735 Tharandt Germany

Restoration forestry （forest rehabilitation） or re-vegetation is one effective measure to solve environmental problems, notably soil erosion. It may be further stimulated by the Clean Development Mechanism for carbon sequestration. However, there is an intensive and on-going debate about the adverse effects arising from afforestation in dryland areas, such as soil drying up which may cause further damage to the success of forest restoration, and the water yield reduction from watershed which may harm the regional development. On other hand, some preliminary studies showed a possibility that these adverse effects may be diminished more or less by properly designing the system structure and spatial distribution of forest/vegetation in a watershed. However, it is urgent to develop an evidence-based and sustainable new forestry policy for harmonizing forest-water interrelation. As a leading country in afforestation, China is beginning to develop a more trans-disciplinary and cross-sectoral forestry policy for harmonizing forestry development with water management. The main points of the changing new forestry policy should include：（1） Establishing a regional development strategy focusing on harmonized forest-water relations; （2） Taking forest-water interactions as an important part of evaluation; （3） Reducing the ＇eco-water＇ quota of forests through technical advancement; （4） Developing and extending water-adaptive forest management practices; （S） Strengthening forest ecohydrological research and decision support ability.

关键词： forest restoration dryland areas water resources integrated management forestry policy China

基于改进FP-Growth算法的CRHX型动车组牵引系统关联失效模型研究

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铁道学报 2016年第9期38卷 72-80页

作者：王艳辉王淑君李曼林帅北京交通大学轨道交通控制与安全国家重点实验室北京100044 北京交通大学交通运输学院北京100044 北京交通大学北京市城市交通信息智能感知与服务工程技术研究中心北京100044

基于CRHX型动车组牵引系统运营过程中的故障数据,分析故障数据的特征,研究设备之间的关联失效关系。依托课题组前期对故障信息特征词提取的研究,本文结合故障信息特征词的特点优化经典的关联规则挖掘算法,提出改进的FP-Growth算法,并进... 详细信息

基于CRHX型动车组牵引系统运营过程中的故障数据,分析故障数据的特征,研究设备之间的关联失效关系。依托课题组前期对故障信息特征词提取的研究,本文结合故障信息特征词的特点优化经典的关联规则挖掘算法,提出改进的FP-Growth算法,并进行算法性能测试,结果表明该算法准确高效;基于改进的FPGrowth算法分析设备的故障信息特征词,挖掘设备关联失效规则,建立设备的关联失效模型。最后,以CRHX型动车组牵引系统为例进行研究,验证了改进FP-Growth算法的有效性和实用性。

关键词：故障信息改进FP-Growth算法关联规则关联失效模型

从《堂邑元寿二年要具簿》解析秦汉徭役制度的几个概念——事、算与事算

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古代文明 2021年第1期15卷 81-90,M0005页

作者：王彦辉东北师范大学历史文化学院吉林长春130024

事、算与事算的含义,在出土的计类文书中基本相同。事的本义是役使,从役使的客体论即事于国,服事于某种义务。算作为计征赋税的一个计算单位,可以算人,也可以算物,依算征收的人头税称赋钱、算钱,民间或称“算赋”。事算即服事于“算”... 详细信息

事、算与事算的含义,在出土的计类文书中基本相同。事的本义是役使,从役使的客体论即事于国,服事于某种义务。算作为计征赋税的一个计算单位,可以算人,也可以算物,依算征收的人头税称赋钱、算钱,民间或称“算赋”。事算即服事于“算”的义务,在县、乡统计赋钱的年度计簿中指的是算钱。《堂邑元寿二年要具簿》应是为上计准备的各种统计数据的底本或草案,其中的“定事口”指的是符合缴纳口钱和算钱的口数,也表示在事口中实际缴纳口钱的口数;“凡筭”指符合缴纳算钱的口数,包括复算和事算人口;“定事筭”即实际缴纳算钱的口数。走马楼吴简“嘉禾四年小武陵乡吏民人名妻子年纪簿”的户计简是为征收“更口筭钱”而编制的最基础账簿,其中,“凡口〇事〇筭〇事〇”的书写格式在口径上与《堂邑元寿二年要具簿》是统一的,但在时态上属于未完成时,“口〇事〇”的“事”指的是应当缴纳口钱(大口钱和小口钱)和算钱的口数,“筭〇事〇”的“事”即“事筭”,指的是应当缴纳算钱的口数。

关键词：事算事算

Coatings for Automotive Truck Production: Demands and Features for Productivity, the Elimination of Casting Defects, Cleanliness and the Environment

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Coatings for Automotive Truck Production: Demands and Featur...

2019中国铸造活动周

作者： Reinhard St?tzel yanhui wang Shengyin Liu Dongshen Yan ASK Chemicals GmbH FAW Foundry Group No.2 foundry plant FAW Foundry Group No.1 foundry plant

Capability and casting quality are the focus of enterprises casting truck components due to the great demand for good and high-quality castings. Having new concepts that can quickly match customer key performance indicators(KPIs) is crucial, e.g. by using sustainable solutions through optimization of the casting process, particularly by using core/mold coatings. Increased demand, for thin-walled castings, for example, the use of advanced alloys, and changes in sand quality, are also causing the technical demands on the applied coating technology to rise, making the use of high-grade coatings unavoidable. The VDA 19(ISO 16232) guideline stipulates a very clear requirement for automotive series castings. The residues in the components are supposed to be limited in order to prolong the maintenance intervals for motor vehicles. Residues in the cavities of engine blocks cause the filters to clog early and are detrimental to the longer maintenance intervals required. The peel-off MIRATEC coating, which has already been tested successfully in practical application, has proven to be an excellent solution to satisfy these ever-rising demands of the OEMs regarding casting cleanliness, defect-free castings and lower casting wall thicknesses. These coatings are rheologically tailored in such a way that even core packages with very complex geometries can be coated in a single step causing fewer flaws and giving higher dimensional accuracy instead of coating several cores separately and assembling them afterwards. Lost-foam casting is a casting technology, which provides designers with the maximum degree of freedom. However, these techniques require high-tech performance coatings to achieve a stable, reproducible casting in a fixed and very narrow range of quality. We have shown that these high-performance coatings enable foundries to produce more complex castings for trucks in a less complicated and more efficient way, which means a competitive advantage for these foundries. Las

关键词： Automotive Truck Coating Productivity Casting defects Environment

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高职学生核心素养框架建构及培养路径

职业技术教育 2017年第19期38卷 35-40页

作者：王艳辉河南大学教育科学学院

随着经济全球化的发展,为培养出适应21世纪需要的技术技能型人才,高职院校必须要构建核心素养框架,基于国外的核心素养研究成果和我国高职教育的人才培养目标,高职学生应该具备工匠精神、技术应用能力、实践创新能力、终身学习能力、信... 详细信息

随着经济全球化的发展,为培养出适应21世纪需要的技术技能型人才,高职院校必须要构建核心素养框架,基于国外的核心素养研究成果和我国高职教育的人才培养目标,高职学生应该具备工匠精神、技术应用能力、实践创新能力、终身学习能力、信息获取能力、人际关系与团队合作能力、外语能力、职业规划发展能力等八大核心素养。政府、学校和学生必须通力合作,从人才培养目标、学业质量评价标准、课程、教学、教师、学风、个人意识等方面综合入手,全面推动高职学生核心素养的培养。

关键词：高职学生核心素养框架人才培养目标培养路径

微重力条件下初始液氢温度对低温推进剂贮箱气枕压力的影响

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空间科学学报 2020年第3期40卷 394-400页

作者：王妍卉周炳红中国科学院大学北京100049 中国科学院国家空间科学中心北京100190

自生增压液氢推进剂贮箱在轨滑行阶段将长期(数百秒)处于微重力环境下,其贮箱压力受多种因素影响.液氢低温推进剂接近饱和温度时,因传热等影响而极易产生相变,从而影响贮箱压力.通过建立贮箱三维CFD模型,研究了不同初始液氢推进剂温度... 详细信息

自生增压液氢推进剂贮箱在轨滑行阶段将长期(数百秒)处于微重力环境下,其贮箱压力受多种因素影响.液氢低温推进剂接近饱和温度时,因传热等影响而极易产生相变,从而影响贮箱压力.通过建立贮箱三维CFD模型,研究了不同初始液氢推进剂温度对于贮箱压力和温度变化等的影响.计算结果表明,气液界面附近推进剂温度与当前气体压力下饱和温度之差(过冷度)越大,压力下降速率越大.随着气体压力下降,气枕温度降低,压力下降速率也逐渐减小,压力变化曲线趋于平缓.在初始液体推进剂温度低于平衡温度的情况下,初始液体推进剂温度越高,平衡压力越高.

关键词：微重力推进剂贮箱液氢相变气枕压力

Attention Points of Research and Education in TCMP across Taiwan Strait and Recommendations for Future Research and Development of TCM in China Mainland Especially Fujian and Taiwan

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Chinese Medicine 2013年第2期4卷 41-51页

作者： Shengyan Xi yanhui wang Yaochen Chuang Linchao Qian Xiaoyan Qian Pengcheng Li Dawei Lu Center of General Education Central Taiwan University of Science and Technology Taichung Taiwan Department of Traditional Chinese Medicine of Medical College Xiamen University Xiamen China

Objective: China mainland and Taiwan are separated by the Taiwan Strait, but their land edges are close to each other, blood relationship is very compact, and the origin is profound, the communication of Traditional Chinese Medicine (TCM) between China mainland especially Fujian and Taiwan district is more and more frequent. From the actuality and situation of traditional Chinese medicine and pharmacy (TCMP), the objective of this study was to briefly expound the points to which attention should be attached urgently in education, research and development of TCM between China mainland especially between Fujian and Taiwan, and be provide with several resolving threads and recommenddations to aim directly at the attention points, and wish it can offer some assistance to the development and generalization of the cross-Strait TCMP. Methods: The China Statistical Yearbook of Chinese Medicine (1987-2010), the Yearbook of Public Health of Taiwan (2009), the full-text data base of China National Knowledge Infrastructure (CNKI) (1993-2009), provides information on research and education in TCMP acrossTaiwan Straitin the last 10 years. The methods of analysis and comparison are applied in this study to show the TCMP situation betweenTaiwanandChinamainland. Result: Due to the differences in history, district, policy and legislation, the TCMP’s industry and trade, education, research and exploitation, standard and so on, have lots of differences betweenTaiwanandChinamainland, and many barriers are produced in the communication and cooperation of cross-Strait TCM and pharmacy. Conclusion: China mainland especially Fujian and Taiwan have the fierce intention to carry out thorough investigation in many territories of TCMP. The prospects and development space of communication and cooperation of cross-Strait TCMP are quite broad.

关键词： Traditional Chinese Medicine and Pharmacy (TCMP) Traditional Chinese Drug Traditional Chinese Medicine (TCM) Chinese Herbal Medicine Research and Development (R&D) China Mainland Fujian and Taiwan District Recommendation

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城市轨道交通车站客流模态与控制策略

东南大学学报（自然科学版） 2015年第6期45卷 1203-1208页

作者：李曼王艳辉贾利民北京交通大学轨道交通控制与安全国家重点实验室北京100044 北京交通大学交通运输学院北京100044

分析城市轨道交通车站系统内部设施客流的流动关系,建立车站内部设施客流演化模型,从系统行为的角度构建城市轨道交通车站客流状态模态集,从而刻画车站客流群体行为演化机理.基于系统动力学给出了客流模态的定义,利用车站系统的站厅客... 详细信息

分析城市轨道交通车站系统内部设施客流的流动关系,建立车站内部设施客流演化模型,从系统行为的角度构建城市轨道交通车站客流状态模态集,从而刻画车站客流群体行为演化机理.基于系统动力学给出了客流模态的定义,利用车站系统的站厅客流、站台客流、中间设施拥挤度等关键变量,分析设施客流之间的非线性作用关系,建立车站内部设施客流演化数学模型.给出模型的解析解,分析并推导了平衡点的存在性和达到稳定的条件,同时给出了相对应模态的物理特征.以北京某典型地铁站为例,根据某工作日的进出站客流量以及满载率的变化情况,利用M atlab软件对模型求解并进行数值模拟,从而得到不同参数下车站客流随时间的变化曲线,并在此基础上给出了车站客流控制策略.

关键词：城市轨道交通客流演化客流模态系统动力学