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海南岛富文金银多金属矿床成矿流体演化:来自流体包裹体和H-O同位素证据

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地球化学 2024年第4期53卷 564-576页

作者：赵朝霞许德如官军单强陈根文陈晓清黄沁怡王智琳中国科学院广州地球化学研究所矿物学与成矿学重点实验室广东广州510640 中国科学院深地科学卓越创新中心广东广州510640 中国科学院大学北京100049 东华理工大学核资源与环境国家重点实验室江西南昌330013 海南省海洋地质资源与环境重点实验室海南省地质调查院海南海口570206 中南大学地球科学与信息物理学院有色金属成矿预测与地质环境监测教育部重点实验室湖南长沙410083

富文金银多金属矿床位于海南岛雷鸣盆地,为中型高硫化物含金石英脉型金矿床。主要金属矿物有自然金、银金矿、黄铁矿、毒砂、闪锌矿、方铅矿及少量黄铜矿;非金属矿物主要为石英、碳酸盐矿物。金的赋存状态主要以含金矿物形式出现,分布... 详细信息

富文金银多金属矿床位于海南岛雷鸣盆地,为中型高硫化物含金石英脉型金矿床。主要金属矿物有自然金、银金矿、黄铁矿、毒砂、闪锌矿、方铅矿及少量黄铜矿;非金属矿物主要为石英、碳酸盐矿物。金的赋存状态主要以含金矿物形式出现,分布于石英、黄铁矿、毒砂裂隙和被包裹在闪锌矿中。该矿床成矿过程可分为早、中、晚3个阶段,其中,中阶段为主成矿阶段,金主要在中阶段沉淀。早阶段流体包裹体为纯CO_(2)型、富CO_(2)型和少量富液相水溶液包裹体,中阶段为纯CO_(2)型、富CO_(2)型、富液相水溶液型和含子矿物多相包裹体,晚阶段为富液相水溶液包裹体。从早阶段到晚阶段,包裹体均一温度峰值分别为320~330℃、205~225℃和130~140℃,盐度峰值分别为3.50%~5.00%NaCl_(eqv)、2.80%~3.50%NaCl_(eqv)和2.25%~3.00%NaCl_(eqv),指示成矿流体以中温、低盐度为特征。包裹体激光拉曼光谱分析表明,富文矿床的流体包裹体成分以H_(2)O为主,富含CO_(2),并含有少量硫化物。主成矿阶段石英中流体包裹体的δD值为−53.9‰~−45.4‰,δ^(18)OH_(2)O值为1.5‰~7.5‰,反映成矿流体具有岩浆水和大气降水两种来源。进一步利用纯CO_(2)包裹体和纯H_(2)O包裹体等容线相交法,估算主成矿阶段的成矿温度为245~315℃,成矿压力为64~130 MPa。综合研究表明,富文矿床是与侵入岩有关的高硫化物金银多金属矿床,其主成矿阶段发生的流体沸腾和不混溶是金沉淀的主要机制。

关键词：流体包裹体 H-O同位素捕获压力激光拉曼富文金银多金属矿床

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糖尿病足发病风险预测模型的系统评价

中国全科医学 2024年第3期27卷 357-363,380页

作者：林令君郭俊王俊伟高杨陈惠盈万永丽天津医科大学朱宪彝纪念医院天津市内分泌研究所国家卫健委激素与发育重点实验室代谢性疾病重点实验室天津市300134

背景糖尿病足是糖尿病患者常见并发症,多数患者病情重,疾病进展快。性能良好的糖尿病足发病风险预测模型可以帮助医务人员识别高危患者,尽早采取干预措施。目的系统评价糖尿病足发病风险预测模型,为模型的构建和优化提供参考。方法检索P... 详细信息

背景糖尿病足是糖尿病患者常见并发症,多数患者病情重,疾病进展快。性能良好的糖尿病足发病风险预测模型可以帮助医务人员识别高危患者,尽早采取干预措施。目的系统评价糖尿病足发病风险预测模型,为模型的构建和优化提供参考。方法检索PubMed、Cochrane Library、Embase、Web of Science、中国知网及万方数据知识服务平台发表的关于糖尿病足风险预测模型的相关文献,检索期限为建库至2023-05-15。由研究者独立筛选文献,并提取文献数据,使用预测模型研究的偏倚风险评估工具(PROBAST)对模型进行质量评价。使用Stata 17.0软件对模型中预测因子进行Meta分析。结果共纳入13篇文献,包含13个模型,其中12个模型的曲线下面积(AUC)>0.7。7个模型进行了模型校准,8个模型进行了验证。PROBAST评估结果显示,纳入的13篇文献中有1篇为低偏倚风险,其余12篇均为高偏倚风险;模型适用性方面,1篇为低适用性。Meta分析结果显示,年龄(OR=1.13,95%CI=1.04~1.24)、糖化血红蛋白(OR=1.56,95%CI=1.26~1.94)、足溃疡史(OR=5.93,95%CI=2.85~12.37)、足截肢史(OR=7.79,95%CI=2.74~22.17)、单丝试验敏感性减弱(OR=1.59,95%CI=1.42~1.78)、足真菌感染(OR=6.14,95%CI=1.71~22.04)、肾病(OR=2.09,95%CI=1.65~2.65)是糖尿病足发病风险的影响因素(P<0.05)。结论糖尿病足风险预测模型仍存在不足,未来风险预测模型的建立可重点关注年龄、糖化血红蛋白水平、足溃疡史、足截肢史、单丝试验敏感性、足真菌感染、肾病等预测因子。

关键词：糖尿病足足溃疡危险性评估预测模型系统评价

Trophic mode and organics metabolic characteristic of fungal community in swine manure composting

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Frontiers of Environmental Science & Engineering 2019年第6期13卷 137-146页

作者： Jing Peng Ke wang Xiangbo Yin xiaoqing Yin Mengfei Du Yingzhi gao Philip Antwi Nanqi Ren Aijie wang School of Environment Harbin Institute of TechnologyHarbin 150090China Architectural Design and Research institute of HIT Harbin Institute of TechnologyHarbin 150090China School of Resources and Environmental Engineering Jiangxi University of Science and TechnologyGanzhou 341000China

The succession of fungal community,trophic mode and metabolic characteristics were evaluated in 60 days composting of swine manure by high-throughput sequencing,FUNGuild and Biolog method,*** result showed that the ftingal community diversity reached to the highest level(76 OTUs)in the thermophilic phase of composting,then sustained decline to 15 OTUs after *** were 10 fungal function groups in the raw swine ***-saprotroph fungi reached to 15.91%on Day-10but disappeared on *** saprotroph-undefined saprotroph fungi grown from 0.19%to 52.39%during the *** ftmgal community had more functional groups but the lower substrate degradation rates in the thermophilic *** fungal communities on Day-0 and Day-60 had the highest degradation rates of amino acids and polymers,*** analysis showed that ORP(49.6%),VS/Ash(45.3%)and moisture(39.2%)were the main influence factors on the succession of fungal community in the swine manure composting process.

关键词： Fungus FUNGuild Biolog Trophic mode Composting Oxidation reduction potential

一株肺炎克雷伯菌的分离鉴定及生物学特性分析

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微生物学通报 2024年第7期51卷 2586-2598页

作者：王帅刘根涂文姬曾成鲁红林信爱国高洪李珂云南农业大学动物医学院云南昆明650201 云南省畜牧兽医科学院养禽与禽病研究所云南昆明650224 云南省野生动植物救护繁育中心云南昆明650224 昆明市濒危动植物收容拯救中心云南昆明650224

【背景】肺炎克雷伯菌是一种人兽共患机会致病菌,可引起多种动物感染且防治难度大。【目的】调查某犀牛驯养场病原菌存在情况。【方法】对随机采集到的6份犀牛粪便进行细菌分离鉴定、耐药情况及相关耐药基因、毒力基因筛查、小鼠致病性... 详细信息

【背景】肺炎克雷伯菌是一种人兽共患机会致病菌,可引起多种动物感染且防治难度大。【目的】调查某犀牛驯养场病原菌存在情况。【方法】对随机采集到的6份犀牛粪便进行细菌分离鉴定、耐药情况及相关耐药基因、毒力基因筛查、小鼠致病性试验。【结果】分离到一株肺炎克雷伯菌,分离率为16.67%。分离株对强力霉素、多黏菌素B、杆菌肽等6种抗生素耐药,且携带有五大类共6种耐药基因。检出kfuBC、fimH、ureA、uge、wabG和wcaG这6种毒力基因。在致病性试验中接种浓度为1×10^(10)CFU/m L时小鼠死亡率高达80%,死亡小鼠肝脏、肺脏和小肠组织有不同程度的病变。【结论】该犀牛驯养场分离到的肺炎克雷伯菌耐药情况严重,耐药基因与耐药表型的复合率低,耐药机制复杂;毒力基因携带情况与致病性试验结果较符合,研究数据可为驯养场防治该菌的潜在感染提供参考。

关键词：肺炎克雷伯菌分离鉴定生物学特性耐药机制

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旋翼巡飞末敏弹动态命中误差仿真研究

弹箭与制导学报 2024年第4期44卷 18-25页

作者：华耀栋王欣胡志鹏贾子琪高昌昊沈阳理工大学装备工程学院辽宁沈阳110159 西安现代控制技术研究所陕西西安710065

针对旋翼巡飞末敏弹末制导段的命中精度受探测系统误差和姿态扰动共同影响的问题,分析了影响EFP毁伤元散布精度的动态特性,建立基于导引系统探测误差、弹体空间姿态扰动、毁伤元牵连运动偏差和系统时延的动态命中点模型,并引入末制导段... 详细信息

针对旋翼巡飞末敏弹末制导段的命中精度受探测系统误差和姿态扰动共同影响的问题,分析了影响EFP毁伤元散布精度的动态特性,建立基于导引系统探测误差、弹体空间姿态扰动、毁伤元牵连运动偏差和系统时延的动态命中点模型,并引入末制导段的弹目交会轨迹与摆动姿态修正,从而在充分利用弹体姿态信息的情况下,利用实验飞行数据,分析各因素对弹着点的影响。仿真和分析结果表明:在一定随机干扰下,巡飞弹弹体姿态扰动和交会轨迹偏差是影响命中精度的主要因素,得出了满足打击典型装甲目标命中率的姿态角控制要求,为巡飞末敏弹的制导律和轨迹预测控制研究提供了理论依据。

关键词：旋翼巡飞末敏弹 EFP毁伤元命中点仿真弹目交会

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Preoperative ultrasound combined with routine blood tests in predicting the malignant risk of pancreatic cystic neoplasms

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Cancer Biology & Medicine 2022年第10期19卷 1503-1516页

作者： Xiuchao wang Junjin wang Xi Wei Lihui Zhao Bo Ni Zekun Li Chuntao gao Song gao Tiansuo Zhao Jian wang Weidong Ma Xiao Hu Jihui Hao Department of Pancreatic Cancer Tianjin Medical University Cancer Institute&HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin’s Clinical Research Center for CancerTianjin 300060China Department of Diagnostic and Therapeutic Ultrasonography Tianjin Medical University Cancer Institute&HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin’s Clinical Research Center for CancerTianjin 300060China Department of Hepatobiliary and Pancreatic Surgery The Affiliated Hospital of Qingdao UniversityQingdao 266000China

Objective:Accurate preoperative identification of benign or malignant pancreatic cystic neoplasms(PCN)may help clinicians make better intervention choices and will be essential for individualized ***:Preoperative ultrasound and laboratory examination findings,and demographic characteristics were collected from *** logistic regression was used to identify independent risk factors associated with malignant PCN,which were then included in the nomogram and validated with an external *** Net Reclassification Index(NRI)and Integrated Discrimination Improvement(IDI)were calculated to evaluate the improvement in the predictive power of the new model with respect to that of a combined imaging and tumor marker prediction ***:Malignant PCN were found in 83(40.7%)and 33(38.7%)of the model and validation cohorts,*** analysis identified age,tumor location,imaging of tumor boundary,blood type,mean hemoglobin concentration,neutrophil-tolymphocyte ratio,carbohydrate antigen 19-9,and carcinoembryonic antigen as independent risk factors for malignant *** calibration curve indicated that the predictions based on the nomogram were in excellent agreement with the actual observations.A nomogram score cutoff of 192.5 classified patients as having low *** risk of malignant *** model achieved good C-statistics of 0.929(95%CI 0.890–0.968,P<0.05)and 0.951(95%CI 0.903–0.998,P<0.05)in predicting malignancy in the development and validation cohorts,***=0.268;IDI=0.271(P<0.001 for improvement).The DCA curve indicated that our model yielded greater clinical benefits than the comparator ***:The nomogram showed excellent performance in predicting malignant PCN and may help surgeons select patients for detailed examination and *** nomogram is freely available at https://***/DynNomapp/.

关键词： Pancreatic cystic neoplasms malignancy prediction nomogram ultrasound blood routine

Machining Deformation prediction of Thin-Walled Part Based on Finite Element analysis

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Journal of Harbin institute of Technology(New Series) 2015年第4期22卷 47-54页

作者： Hongxiang wang Yabin Tang Zhanshan Liu Shi gao School of Mechanical Electrical Engineering Harbin Institute of Technology Jiangnan institute of Computing Technology

For the problems of machining distortion and the low accepted product during milling process of aluminum alloy thin-walled part,this paper starts from the analysis of initial stress state in material preparation process,the change process of residual stress within aluminum alloy pre-stretching plate is researched,and the distribution law of residual stress is indirectly obtained by delamination measurement methods,so the effect of internal residual stress on machining distortion is considered before finite element simulation. Considering the coupling effects of residual stress,dynamic milling force and clamping force on machining distortion,a threedimensional dynamic finite element simulation model is established,and the whole cutting process is simulated from the blank material to finished product,a novel prediction method is proposed,which can availably predict the machining distortion accurately. The machining distortion state of the thin-walled part is achieved at different processing steps,the machining distortion of the thin-walled part is detected with three coordinate measuring machine tools,show that the simulation results are in good agreement with experimental data.

关键词： thin-walled part machining deformation residual stress aluminum alloy finite element simulation

煤矿导水裂隙带影响因素敏感性及高度预测研究

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中国矿业 2024年第10期33卷 193-201页

作者：李晓斌李全生李金松刘小庆李井峰方杰张勇王路军张传玖北京低碳清洁能源研究院煤炭开采水资源保护与利用全国重点实验室北京102209 国家能源投资集团有限责任公司北京100011 煤炭科学研究总院有限公司北京100013 国家能源神东煤炭集团有限责任公司技术研究院陕西榆林719315

研究导水裂隙带高度是含水层修复和地表生态保护的重要基础,明确其影响因素的敏感性排序,有利于抓住主要矛盾,安全高效地实现矿井水预防。本文采用现场实测、数值模拟和数学统计方法,分析了导水裂隙带高度与岩层硬度、工作面长度、采高... 详细信息

研究导水裂隙带高度是含水层修复和地表生态保护的重要基础,明确其影响因素的敏感性排序,有利于抓住主要矛盾,安全高效地实现矿井水预防。本文采用现场实测、数值模拟和数学统计方法,分析了导水裂隙带高度与岩层硬度、工作面长度、采高和埋深的内在联系,得到了导水裂隙带高度计算公式,并在现场得到应用。通过研究可知:导水裂隙带高度在硬岩中传导更快,而软岩可以抑制导水裂隙带高度。软岩与硬岩组合(下软上硬)导水裂隙带高度大于硬岩与软岩组合(下硬上软)导水裂隙带高度。开采方法会影响导水裂隙带高度,综放开采导水裂隙带高度大于厚煤层分层开采、单一薄煤层开采、单一中厚煤层开采。各因素影响导水裂隙带高度的程度为:采高>硬岩岩性比例系数>采深>工作面长度。与“三下”规程经验公式相比,利用多因素拟合公式可以较好地实现乌兰木伦煤矿12403工作面导水裂隙带高度预测,误差仅为−2.54%,研究成果为地下水资源保护和水害治理提供指导依据。

关键词：岩性组合多因素分析导水裂隙带高度敏感性预测公式

Characteristics of Late-Quaternary Activity and Seismic Risk of the Northeastern Section of the Longmenshan Fault Zone

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Acta Geologica Sinica(English Edition) 2013年第6期87卷 1674-1689页

作者： wang Mingming ZHOU Bengang YANG Xiaoping XIE Chao gao Xianglin Key Laboratory of Active Tectonics and Volcano Institute of Geology CEA Sichuan Seistech Corporation Ltd. Key Laboratory of Earthquake prediction Institute of Earthquake Science CEA institute of Geology CEA

Following the 2008 Wenchuan M8 earthquake,the seismic risk of the northeastern section of the Longmenshan fault zone and the adjacent Hanzhong basin has become an issue that receives much *** is facing,however,the problem of a lack of sufficient data because of little previous work in these *** northeastern section of the Longmenshan fault zone includes three major faults：the Qingchuan fault,Chaba-Lin＇ansi fault,and Liangshan south margin fault,with the Hanzhong basin at the northern *** paper presents investigations of the geometry,motion nature,and activity ages of these three faults,and reveals that they are strike slip with normal faulting,with latest activity in the Late *** implies that this section of the Longmenshan fault zone has been in an extensional setting,probably associated with the influence of the Hanzhong *** analysis of the tectonic relationship between the Longmenshan fault zone and the Hanzhong basin,this work verifies that the Qingchuan fault played an important role in the evolution of the Hanzhong basin,and further studies the evolution model of this ***,with consideration of the tectonic setting of the Longmenshan fault zone and the Hanzhong basin as well as seismicity of surrounding areas,this work suggests that this region has no tectonic conditions for great earthquakes and only potential strong events in the future.

关键词： Seismic risk northeastern Longmenshan fault zone Hanzhong basin Late-Quaternary activity