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肺移植术后原发性移植物失功患者行体外膜肺氧合支持下俯卧位通气的护理

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中华急危重症护理杂志 2024年第1期5卷 40-43页

作者：冯世萍王海翔王大鹏浦敏华南京医科大学附属无锡人民医院心肺ICU 无锡市214023

总结8例肺移植术后重度原发性移植物失功患者行体外膜肺氧合支持下俯卧位通气治疗的护理经验。针对该组患者液体控制、气道维护、俯卧位通气、肺康复等问题,采取精准化液体管理、加强肺水肿期间气道管理、基于患者安全的综合措施、早期... 详细信息

总结8例肺移植术后重度原发性移植物失功患者行体外膜肺氧合支持下俯卧位通气治疗的护理经验。针对该组患者液体控制、气道维护、俯卧位通气、肺康复等问题,采取精准化液体管理、加强肺水肿期间气道管理、基于患者安全的综合措施、早期肺康复训练等护理措施。7例患者顺利转入移植病房,1例因多脏器功能衰竭死亡。

关键词：肺移植原发性移植物功能障碍体外膜氧合作用俯卧位危重病护理

Efficacy and safety of Huzhang Granule,a compound Chinese herbal medicine,for acute gouty arthritis:A double-blind,randomized controlled trial

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Journal of Integrative Medicine 2024年第3期22卷 270-278页

作者： Hao wang Si-ting Chen Xiao-jie Ding Le Kuai Liang Hua Xin Li Yi-fei wang Ming Zhang Bin Li Rui-ping wang Mi Zhou Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Institute of Dermatology Shanghai Academy of Traditional Chinese MedicineShanghai 201203China Department of Dermatology the Affiliated Hospital of Jiangxi University of Chinese MedicineNanchang 330000Jiangxi ProvinceChina Shanghai Skin Disease Hospital School of MedicineTongji UniversityShanghai 200443China Institute of Dermatology School of MedicineTongji UniversityShanghai 200443China

Background:Acute gouty arthritis(AGA)is an inflammatory joint disease with a high *** medical interventions,including nonsteroidal anti-inflammatory drugs,colchicine and glucocorticoids,can have serious adverse *** Granule(HZG),a compound Chinese herbal medicine,has been used to treat AGA for more than 30 years with satisfactory effects and no significant adverse ***,the efficacy and safety of HZG in AGA patients remains ***:The present investigation was designed to examine the efficacy and safety profile of HZG in managing AGA ***,setting,participants and interventions:The current study was conducted as a noninferiority,randomized controlled clinical trial on 180 eligible enrolled *** were randomly assigned into the HZG and etoricoxib *** were administered for 5 d,during which the HZG group received HZG and placebo etoricoxib,while the etoricoxib group received etoricoxib and placebo HZG in the same ratio(1:1).Main outcome measures:The primary outcome was pain experienced by the patient in the gout-afflicted joint from days 2 to 5 of the treatment *** pain level was measured via a visual analogue scale,ranging from 0 mm to 100 *** secondary outcomes comprised joint tenderness and swelling,reduction of inflammatory biomarkers,and the patient’s and investigator’s global evaluations of therapeutic ***:The mean reduction in pain was-51.22 mm(95%confidence interval[CI],[-53.42,-49.03]mm)for the HZG and-52.00 mm(95%CI,[-54.06,-49.94]mm)for the etoricoxib *** mean difference between the two groups was 0.78 mm(95%CI,[-2.25,3.81]mm).All additional efficacy endpoints,covering decreased inflammation and pain relief,yielded compelling proof of *** in the HZG group exhibited a comparatively lower rate of adverse events compared to those in the etoricoxib group(4.44%vs 13.33%;P≤0.05).Conclusion:HZG and etoricoxib groups demons

关键词： Acute gouty arthritis Huzhang Granule Randomized controlled trial Blind

深海采矿装备布放回收过程中脐带缆动力学响应特性研究

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矿冶工程 2024年第1期44卷 12-15,20页

作者：王伟陈时平张明双志吴卓长沙矿冶研究院有限责任公司深海矿产资源开发利用技术国家重点实验室湖南长沙410012

基于时域耦合分析法,建立了母船-深海采矿装备-脐带缆三维非线性水动力学模型,并对布放及回收过程中脐带缆的水动力响应特性进行了数值计算与分析。结果表明,4级海况时,深海采矿装备(水中重10 t)可以在速度0.8 m/s条件下安全布放和回收... 详细信息

基于时域耦合分析法,建立了母船-深海采矿装备-脐带缆三维非线性水动力学模型,并对布放及回收过程中脐带缆的水动力响应特性进行了数值计算与分析。结果表明,4级海况时,深海采矿装备(水中重10 t)可以在速度0.8 m/s条件下安全布放和回收;在波浪和海流共同作用下,深海采矿装备在布放开始阶段和回收结束阶段都有强烈的振荡和摆幅,可安装防摇止荡装置来降低振荡和摆动。

关键词：深海采矿装备深海采矿系统布放回收脐带缆动力学响应

Kinematic deformation and intensity assessment of the 2021 Maduo M_(S)7.4 earthquake in Qinghai revealed by high-frequency GNSS

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Geodesy and Geodynamics 2024年第3期15卷 230-240页

作者： Yu Li Yuebing wang Lijiang Zhao Hongbo Shi Pingping wang Institute of Geophysics China Earthquake AdministrationBeijing 100081China china Earthquake Networks Center China Earthquake AdministrationBeijing 100045China Qinghai Institute of Geological Surveying and Mapping Geographic Information Qinghai 810001China beijing Sixents Technology Co. Ltd.Beijing 100094China

Rapid acquisition of the kinematic deformation field and seismic intensity distribution of large earthquakes is crucial for postseismic emergency rescue,disaster assessment,and future seismic risk *** advancement of GNSS observation and data processing makes it play an important role in this field,especially the high-frequency *** used the differential positioning method to calculate the 1 HZ GNSS data from 98 sites within 1000 km of the M_(S)7.4 Maduo earthquake *** kinematic deformation field and the distribution of the seismic intensity by using the peak ground velocity derived from displacement waveforms were *** results show that:1)Horizontal coseismic response deformation levels ranging from 25 mm to 301 mm can be observed within a 1000 km radius from the *** response deformation on the east and west sides shows bilateral asymmetry,which markedly differs from the symmetry presented by surface rupture.2)The seismic intensity obtained through high-frequency GNSS and field investigations exhibits good consistency of the scope and orientation in the high seismic intensity area,although the former is generally slightly smaller than the latter.3)There may exist obstacles on the eastern side of the seismogenic *** Maduo earthquake induced a certain tectonic stress loading effect on the western Kunlun Pass-Jiangcuo fault(KPJF)and Maqin-Maqu segment,resulting in higher seismic risk in the future.

关键词： Maduo earthquake High-frequency GNSS Kinematic deformation Seismic intensity

猕猴桃溃疡病病原菌MLVA分型引物的筛选及验证

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果树学报 2024年第6期41卷 1188-1198页

作者：姚令王海黄露安星宇陈文王莉爽薛原吴石平贵州省农业科学院植物保护研究所·农业农村部喀斯特山区作物基因资源与种质创新重点实验室贵阳550006 贵州省农业科学院农业科技信息研究所贵阳550006 贵州省烟草公司安顺市公司贵州安顺561000

【目的】筛选出一组可精准快速地对丁香假单胞菌猕猴桃致病变种(Pseudomonas syringae ***,Psa)进行分型的引物组合。【方法】针对前期文献已报道的34对引物,采用PCR技术验证该34对引物对中国Psa菌株的扩增效率及准确性;利用模拟PCR获... 详细信息

【目的】筛选出一组可精准快速地对丁香假单胞菌猕猴桃致病变种(Pseudomonas syringae ***,Psa)进行分型的引物组合。【方法】针对前期文献已报道的34对引物,采用PCR技术验证该34对引物对中国Psa菌株的扩增效率及准确性;利用模拟PCR获取菌株串联重复(TR)数;以辛普森指数(Simpson’s index,SI)作为筛选引物组合的标准,基于R软件平台,筛选最优引物组合。【结果】34对引物对中国Psa扩增效果均良好,其中TR14与TR11II、TR19与Psa-01引物序列相同;TR8与Psa-08、TR39II与Psa-10、GM-1834与TR10I、GM-1553与TR64II、TR19Psa-01与TR19II扩增同一TR;Psa-09扩增产物串联重复单元长度不唯一,TR2II扩增产物侧翼变异较大,不能通过电泳确定串联重复数;最终确定SI值与全部引物组合相同的最低引物数量为9对,使用该9对引物的组合可将Psa已知的5种生物型准确分开。【结论】TR23/Psa-04、Psa-03、Psa-05、Psa-06、TR10IGM-1834、TR30I、TR1II、Psa-10TR39II、TR64IIGM-1553等9对引物可代表当前文献报道的34对引物,进行Psa分型研究,探索猕猴桃溃疡病的传播和流行规律,为病害防控策略的制定提供科学依据。

关键词：丁香假单胞菌猕猴桃致病变种多位点串联重复序列分析群体遗传结构引物筛选

EVOLUTIONAL FEATURES OF INTERANNUAL LOW-FREQUENCY OSCILLATIONS AND THEIR RELATION TO THE OCCURRENCE OF EL NINO

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Acta meteorologica Sinica 1989年第3期3卷 352-365页

作者：陈隆勋阎敬华王谷 Academy of meteorological Science State Meteorological Administration Beijing

A simplified data set with 8°×8° grid system in a region of 32°S--32°N from 1951 to 1979 for the elements of sea surface temperature (SST), zonal wind at sea level (U), sea level pressure (SLP) and total cloud amount (CA) is made from the COADS. The oscillation components with periods of 2 years (QBO), 3.5 years (SO) and 5.5 years (FYO) in interannual low-frequency oscillations have been studied by using the methods of extended EOF (EEOF) and lag correlation analysis with the oscillational components of SST in the equator of eastern Pacific as the reference element. In our paper, the relationship between oscilla- tion components and occurrence of El Nino is also investigated.

关键词： QBO EVOLUTIONAL FEATURES OF INTERANNUAL LOW-FREQUENCY OSCILLATIONS AND THEIR RELATION TO THE OCCURRENCE OF EL NINO SSTA Nino EL

An inulin-type fructan CP-A from Codonopsis pilosula attenuates experimental colitis in mice by promoting autophagy-mediated inactivation of NLRP3 inflammasome

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Chinese Journal of Natural Medicines 2024年第3期22卷 249-264页

作者： ZHOU Jiangtao wang Jun wang Jiajing LI Deyun HOU Jing LI Jiankuan BAI Yun’e GAO Jianping School of Pharmaceutical Science Shanxi Medical UniversityJinzhong 030600China

Inulin-type fructan CP-A,a predominant polysaccharide in Codonopsis pilosula,demonstrates regulatory effects on immune activity and *** efficacy of CP-A in treating ulcerative colitis(UC)is,however,not *** study employed an in vitro lipopolysaccharide(LPS)-induced colonic epithelial cell model(NCM460)and an in vivo dextran sulfate sodium(DSS)-induced colitis mouse model to explore CP-A’s protective effects against experimental colitis and its underlying *** monitored the clinical symptoms in mice using various parameters:body weight,disease activity index(DAI),colon length,spleen weight,and histopathological ***,molecular markers were assessed through enzyme-linked immunosorbent assay(ELISA),quantitative real-time polymerase chain reaction(qRT-PCR),immunofluorescence(IF),immunohistochemistry(IHC),and Western blotting *** showed that CP-A significantly reduced reactive oxygen species(ROS),tumor necrosis factor-alpha(TNF-α),and interleukins(IL-6,IL-1β,IL-18)in LPS-induced cells while increasing IL-4 and IL-10 levels and enhancing the expression of Claudin-1,ZO-1,and occludin proteins in NCM460 ***,in vivo findings revealed that CPA administration markedly improved DAI,reduced colon shortening,and decreased the production of myeloperoxidase(MPO),malondialdehyde(MDA),ROS,IL-1β,IL-18,and NOD-like receptor protein 3(NLRP3)inflammasome-associated genes/proteins in UC ***-A treatment also elevated glutathione(GSH)and superoxide dismutase(SOD)levels,stimulated autophagy(LC3B,P62,Beclin-1,and ATG5),and reinforced Claudin-1 and ZO-1 expression,thereby aiding in intestinal epithelial barrier repair in colitis ***,the inhibition of autophagy via chloroquine(CQ)diminished CP-A’s protective impact against colitis in *** findings elucidate that CP-A’s therapeutic effect on experimental colitis possibly involves mitigating intestinal inflammation through autophagymediated N

关键词： Inulin-type fructan CP-A Codonopsis pilosula Ulcerative colitis NLRP3 inflammasome Autophagy

A fusion algorithm for remote sensing images based on nonsubsampled pyramids and bidimensional empirical decomposition

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Science china(Technological Sciences) 2010年第S1期53卷 196-204页

作者： ZHANG XiaoDong 1,wang WenBo 2,wang DiFeng 3 & ZHANG Yu 4 1 state Key Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,Wuhan 430079,china 2 College of Sciences,Wuhan University of Science and Technology,Wuhan 430065,china 3state Key Laboratory of Satellite Ocean Environment Dynamics,Second Institute of Oceanography,state Oceanic administration,Hangzhou 310012,china 4 Spatial Information Technology Application Research Institute,Changjiang River Scientific Research Institute,Wuhan 430010,china Wuhan Univ State Key Lab Informat Engn Surveying Mapping & R Wuhan 430079 Peoples R China Wuhan Univ Sci & Technol Coll Sci Wuhan 430065 Peoples R China state Ocean Adm Inst Oceanog 2 State Key Lab Satellite Ocean Environm Dynam Hangzhou 310012 Zhejiang Peoples R China Changjiang River Sci Res Inst Spatial Informat Technol Applicat Res Inst Wuhan 430010 Peoples R China

In order to improve the quality of remote sensing image fusion,a new method combining nonsubsampled Laplacian pyramid (NLP)and bidimensional empirical mode decomposition(BEMD)is ***,the high resolution panchromatic image (PAN)is decomposed using NLP until the approximate component and the low resolution multispectral image(MS)contain features with a similar ***,the approximation component and the MS are decomposed by BEMD,resulting in a number of bidimensional intrinsic mode functions(BIMF)and a residue *** instantaneous frequency is computed in 4 directions of the *** the positive or negative coefficients in the corresponding position,a weighted algorithm is designed for fusing the high frequency details using the instantaneous frequency and the coefficient absolute value of the BIMFs as fusion *** fused image is then obtained through inverse BEMD and *** results have illustrated the advantage of this method over the IHS,DWT andà-Trous wavelet in both spectral and spatial detail qualities.

关键词： bidimensional empirical mode decomposition nonsubsampled pyramid instantaneous frequency remote sensing image fusion

Dynamic recrystallization during hot torsion of Al-4Mg alloy

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Journal of University of Science and Technology beijing 2003年第2期10卷 45-48页

作者： Junpin Lin, Yanli wang, Zhi Lin, and Guoliang Chenstate Key Laboratory of Advanced Metal Materials, University of Science and Technology beijing, beijing 100083, china Lab. of Adv. Metal Mat. Univ. of Sci. and Technol. Beijing Beijing 100083 China

Binary Al-4Mg alloy have been deformed by hot torsion at 300-500 deg C andstrain rates of 0.006-1.587 s^(-1) to a true strain of 5.5. The specimens were annealed in vacuumfor 1.5 h at 500 deg C and then water quenched. The study indicates that the dynamicrecrystallization occurs during hot torsion of Al-4Mg alloy in a certain range of Z parameter(Zener-Hollmon Parameter), i.e. 19.3 <= lnZ <=24.8. Increasing the strain rate at higher deformationtemperature or reducing the strain rate at lower deformation temperature accelerates the occurrenceof dynamic recrystallization in the alloy.

关键词： Al-4Mg alloy dynamic recrystallization hot torsion