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RESEARCH ON PLM MULTIDIMENSIONAL DATA MODEL

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RESEARCH ON PLM MULTIDIMENSIONAL DATA MODEL

Oxygen vacancies enriched Ir/WOx catalysts for the directly chem-catalytic conversion of cellulose to ethanol

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： wang Zhen*, wang lifeng, rui Yuxiang, li congxin (IEEE member) *Teaching Administration Office, Shanghai Institute of Technology, Shanghai 200235, China National Die &Mould CAD Engineering Research Centre, Shanghai Jiaotong University, Shanghai 200030, China

In today’s challenging global market, companies areembracing PLM (Product lifecycle Management) as animportant information strategy to achieve their business goalsof T (time), Q (quality), C (cost), S

关键词： PLM multidimensional data model tealizationframework.

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Tungsten 2025年第1期7卷 88-99页

作者： Yu-Jing Weng Zhao-Ying Ding Ying-Chao li Yuan-Feng Wu Yuan-Yang Xu rui Chen Xiao-Lei Zhao Hai-Yong wang Da-Lei Zhang Yu-Long Zhang Henan Key Laboratory of Coal Green Conversion and International Joint Laboratory of Coal Clean Utilization College of Chemistry and Chemical Engineering Henan Polytechnic University Key Laboratory of Renewable Energy Guangzhou Institute of Energy Conversion Chinese Academy of Sciences liaoning Institute of Energy Technology

Tungsten and its oxides are highly versatile catalysts with unique properties that hold great promise for a wide array of applications,including biological pathways and chemical *** chemo-catalysis of cellulose to ethanol presents a promising avenue for ethanol synthesis with the potential for enhanced efficiency compared to conventional methods,offering a sustainable and carbon-neutral alternative to existing petrochemical and biological ***,Ir/WOxcatalysts enriched with oxygen vacancies were meticulously prepared and demonstrated remarkable catalytic performance in converting cellulose to ethanol directly in the presence of tungstic *** catalyst achieved a high ethanol yield of 66.5%under optimal reaction conditions,approaching the theoretical yield limit of traditional ethanol *** results revealed the presence of oxygen defects,Bronsted/Lewis acidity,and Ir nanoclusters on the catalyst surface,working synergistically to facilitate the cascade catalysis of cellulose hydrolysis,sugar retro-aldol condensation reaction,and C2 intermediate hydrodeoxygenation to *** situ Fourier transform infrared spectrometer analysis confirmed the catalyst's ability to enhance the adsorption and activation of ethylene glycol for ethanol *** manipulating subtle structural features,this study offers a fresh perspective on tungsten group catalyst design and underscores the importance of synergistic effects among catalytic sites for the efficient production of ethanol from cellulose.

关键词： Cellulosic ethanol Chem-catalysis Hydrogenolysis Retro-aldol condensation Tungsten

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying wang Yan Sun lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith rui li Nai-Kui liu Xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-Jian Tang Yuan-Ming Pan Wei li rui-Qiong Ma Jian-liu wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

基于应急疏散的滨海地下交通枢纽空间精细化分区研究

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灾害学 2025年第1期40卷 227-234页

作者：瞿扬李彦潼张赫王睿天津大学建筑学院天津300072

暴雨和洪涝对滨海城市的地下空间构成严重威胁,应急疏散效率在受灾场景中至关重要。研究表明空间分区能有效提高疏散效率。目前传统分区方法依赖单一的最短路径方法,无法兼顾安全与高效。该文基于安全性评估提出了一种精细化分区方法。... 详细信息

暴雨和洪涝对滨海城市的地下空间构成严重威胁,应急疏散效率在受灾场景中至关重要。研究表明空间分区能有效提高疏散效率。目前传统分区方法依赖单一的最短路径方法,无法兼顾安全与高效。该文基于安全性评估提出了一种精细化分区方法。首先以应急疏散为目的,对地下空间按功能划分;其次考虑到灾害风险性、人员聚集性和设施高效性三个维度的影响因素,并构建安全性分区评价体系;最后综合上述因素,构建精细化分区划定体系。文章以深圳红树湾地铁站为案例,验证了新方法在保障疏散安全的同时,提升了疏散效率,为地下交通枢纽的防灾规划提供了理论支持。

关键词：地下交通枢纽空间应急疏散安全性分区精细化分区

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基于系统动力学的应急物资协同储备模型研究

灾害学 2025年第1期40卷 153-159页

作者：王剑伟凌大荣李德李睿赵爽陆军勤务学院重庆401311

该文探讨了在应急物资保障过程中,如何有效解决初期末端物资供应不足和后期物资库存过剩的问题。通过分析应急物资保障过程中的相关因素,运用先分解后耦合的系统工程法构建了应急物资协同储备系统动力学模型。以中国西南地区某省为例,... 详细信息

该文探讨了在应急物资保障过程中,如何有效解决初期末端物资供应不足和后期物资库存过剩的问题。通过分析应急物资保障过程中的相关因素,运用先分解后耦合的系统工程法构建了应急物资协同储备系统动力学模型。以中国西南地区某省为例,模拟应对较大规模地震灾害的情况,利用Vemsin PLE软件对模型进行分析,得到优化方案。研究表明:①加大末端物资储备量,尤其是交通不便地区,能有效应对前期物资需求;②通过调整末端与上级的期望物资使用天数,可大幅减少物资总库存量,提高经济性;③降低物资总库存量能减小库存波动幅度,增强物资供应链路的稳定性。通过上述分析,为优化应急物资储备模式提供了参考,有助于提升应急管理的效率和效果。

关键词：系统动力学应急物资协同储备模拟仿真

Experimental and numerical investigation of the influence of roughness and turbulence on LUT airfoil performance

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Acta Mechanica Sinica 2019年第6期35卷 1178-1190页

作者： Shoutu li Ye li congxin Yang Xiaobo Zheng Qing wang Yin wang Deshun li Wenrui Hu School of Energy and Power Engineering Lanzhou University of TechnologyLanzhou 730050China Gansu Provincial Technology Centre for Wind Turbines Lanzhou 730050China Key Laboratory of Fluid Machinery and Systems Lanzhou 730050China Lab of Multiple Function Towing Tank School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Ocean Engineering School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Hydrodynamics(Ministry of Education) Shanghai Jiao Tong UniversityShanghai 200240China Institute of Mechanics Chinese Academy of SciencesBeijing 100080China

Vertical-axis wind turbines(VAWTs)have been widely used in urban environments,which contain dust and experience strong ***,airfoils for VAWTs in urban environments have received considerably less research attention than those for horizontal-axis wind turbines(HAWTs).In this study,the sensitivity of a new VAWT airfoil developed at the Lanzhou University of Technology(LUT)to roughness was investigated via a wind tunnel *** results show that the LUT airfoil is less sensitive to roughness at a roughness height of<0.35 ***,the drag bucket of the LUT airfoil decreases with increasing roughness ***,the loads on the LUT airfoil during dynamic stall were studied at different turbulence intensities using a numerical method at a tip-speed ratio of *** the stall,the turbulence intensity did not considerably affect the normal or tangential force coefficients of the LUT ***,after the stall,the normal force coefficient varied obviously at low turbulence ***,as the turbulence intensity increased,the normal and tangential force coefficients decreased rapidly,particularly in the downwind region of the VAWT.

关键词： Airfoil Dynamic load Roughness Vertical-axis wind turbines(VAWTs) Wind tunnel experiment

Verification and validation of detonation modeling

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Defence Technology（防务技术） 2019年第3期15卷 398-408页

作者： Xiao liang rui-li wang Institute of Applied Physics and Computational Mathematics Beijing 100094 China College of Mathematics and Information Science Shandong University of Science and Technology Qingdao 266590 China

The mathematical model used to describe the detonation multi-physics phenomenon is usually given by highly coupled nonlinear partial differential equations. Numerical simulation and the computer aided engineering (CAE) technique has become the third pillar of detonation research, along with theory and experiment, due to the detonation phenomenon is difficult to explain by the theoretical analysis, and the cost required to accredit the reliability of detonation products is very high, even some physical experiments of detonation are impossible. The numerical simulation technique can solve these complex problems in the real situation repeatedly and reduce the design cost and time stunningly. But the reliability of numerical simulation software and the serviceability of the computational result seriously hinders the extension, application and the self-restoration of the simulation software, restricts its independently innovational ability. This article deals with the physical modeling, numerical simulation, and software development of detonation in a unified way. Verification and validation and uncertainty quantification (V&V&UQ) is an important approach in ensuring the credibility of the modeling and simulation of detonation. V&V of detonation is based on our independently developed detonation multiphysics software-LAD2D. We propose the verification method based on mathematical theory and program function as well as availability of its program execution. Validation is executed by comparing with the experiment data. At last, we propose the future prospect of numerical simulation software and the CAE technique, and we also pay attention to the research direction of V&V&UQ.

关键词： Verification and validation Detonation Equation of state Detonation diffraction Reaction rate law

The role of hydrostatic pressure on the metal corrosion in simulated deep-sea environments—a review

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Journal of Materials Science & Technology 2022年第17期112卷 230-238页

作者： rui liu li liu Fuhui wang Shenyang National Laboratory for Materials Science Northeastern UniversityNO.3-11 Wenhua RoadShenyang 110819China

This paper reviewed the corrosion behavior of metals in simulated deep-water environments and briefly discussed the effect of hydrostatic pressure on the different corrosion types for the active and the passive alloys.A consensus on the corrosion mechanism is that hydrostatic pressure accelerates the dissolution kinetics,changes the chemical compositions of the product layer or passive films,and promotes the adsorption of Cl^(-)on the metal *** addition,a newly-developed mechanism that hydrostatic pressure facilitates the dissolution process by thinning the electric double layer was reviewed,the synergistic effect of hydrostatic pressure and tensile stress on the stress corrosion cracking was discussed,and the modified coating with chemical bonding interface to prolong the service life in this environment was introduced.

关键词： Corrosion Hydrostatic pressure Deep-sea environments